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Items: 1 to 20 of 25

1.
Caenorhabditis elegans RIG-I-like receptor DRH-1 signals via CARDs to activate antiviral immunity in intestinal cells
Lakshmi E. Batachari, Alyssa Y. Dai, Emily R. Troemel
Proc Natl Acad Sci U S A. 2024 Jul 16; 121(29): e2402126121. Published online 2024 Jul 9. doi: 10.1073/pnas.2402126121
PMCID:
PMC11260149
AbstractArticlePDF–4.7M
2.
A dicer-related helicase opposes the age-related pathology from SKN-1 activation in ASI neurons
Chris D. Turner, Nicole L. Stuhr, Carmen M. Ramos, Bennett T. Van Camp, Sean P. Curran
Proc Natl Acad Sci U S A. 2023 Dec 26; 120(52): e2308565120. Published online 2023 Dec 19. doi: 10.1073/pnas.2308565120
PMCID:
PMC10756303
AbstractArticlePDF–2.2M
3.
The Caenorhabditis elegans ARIP-4 DNA helicase couples mitochondrial surveillance to immune, detoxification, and antiviral pathways
Kai Mao, Peter Breen, Gary Ruvkun
Proc Natl Acad Sci U S A. 2022 Dec 6; 119(49): e2215966119. Published online 2022 Nov 29. doi: 10.1073/pnas.2215966119
PMCID:
PMC9894117
AbstractArticlePDF–3.5M
4.
ER-associated RNA silencing promotes ER quality control
Sotirios Efstathiou, Franziska Ottens, Lena-Sophie Schütter, Sonia Ravanelli, Nikolaos Charmpilas, Aljona Gutschmidt, Jérémie Le Pen, Niels H. Gehring, Eric A. Miska, Jorge Bouças, Thorsten Hoppe
Nat Cell Biol. 2022; 24(12): 1714–1725. Published online 2022 Dec 5. doi: 10.1038/s41556-022-01025-4
PMCID:
PMC9729107
AbstractArticlePDF–7.1M
5.
Functional identification of microRNA-centered complexes in C. elegans
Shilpa Hebbar, Ganesh Panzade, Ajay A. Vashisht, James A. Wohlschlegel, Isana Veksler-Lublinsky, Anna Y. Zinovyeva
Sci Rep. 2022; 12: 7133. Published online 2022 May 3. doi: 10.1038/s41598-022-10771-2
PMCID:
PMC9065084
AbstractArticlePDF–2.2M
6.
The transcription factor ZIP-1 promotes resistance to intracellular infection in Caenorhabditis elegans
Vladimir Lažetić, Fengting Wu, Lianne B. Cohen, Kirthi C. Reddy, Ya-Ting Chang, Spencer S. Gang, Gira Bhabha, Emily R. Troemel
Nat Commun. 2022; 13: 17. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27621-w
PMCID:
PMC8748929
AbstractArticlePDF–2.7M
7.
Mitochondrial dysfunction induces RNA interference in C. elegans through a pathway homologous to the mammalian RIG-I antiviral response
Kai Mao, Peter Breen, Gary Ruvkun
PLoS Biol. 2020 Dec; 18(12): e3000996. Published online 2020 Dec 2. doi: 10.1371/journal.pbio.3000996
PMCID:
PMC7735679
AbstractArticlePDF–2.2M
8.
Purification and Characterization of Double-Stranded Nucleic Acid-Dependent ATPase Activities of Tagged Dicer-Related Helicase 1 and its Short Isoform in Caenorhabditis elegans
Taishi Kobayashi, Takuro Murakami, Yuu Hirose, Toshihiko Eki
Genes (Basel) 2020 Jul; 11(7): 734. Published online 2020 Jul 1. doi: 10.3390/genes11070734
PMCID:
PMC7397212
AbstractArticlePDF–2.3M
9.
The Caenorhabditis elegans RIG-I Homolog DRH-1 Mediates the Intracellular Pathogen Response upon Viral Infection
Jessica N. Sowa, Hongbing Jiang, Lakshmi Somasundaram, Eillen Tecle, Guorong Xu, David Wang, Emily R. Troemel
J Virol. 2020 Jan; 94(2): e01173-19. Prepublished online 2019 Oct 16. Published online 2020 Jan 6. doi: 10.1128/JVI.01173-19
PMCID:
PMC6955277
AbstractArticlePDF–5.2M
10.
OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes
Woojin Kim, Ryan S. Underwood, Iva Greenwald, Daniel D. Shaye
Genetics. 2018 Oct; 210(2): 445–461. Published online 2018 Aug 17. doi: 10.1534/genetics.118.301307
PMCID:
PMC6216590
AbstractArticlePDF–1.4M
11.
Terminal uridylyltransferases target RNA viruses as part of the innate immune system
Jérémie Le Pen, Hongbing Jiang, Tomás Di Domenico, Emma Kneuss, Joanna Kosałka, Christian Leung, Marcos Morgan, Christian Much, Konrad L. M. Rudolph, Anton J. Enright, Dónal O’Carroll, David Wang, Eric A. Miska
Nat Struct Mol Biol. Author manuscript; available in PMC 2019 Feb 13.
Published in final edited form as: Nat Struct Mol Biol. 2018 Sep; 25(9): 778–786. Published online 2018 Aug 13. doi: 10.1038/s41594-018-0106-9
PMCID:
PMC6130846
AbstractArticlePDF–2.0M
12.
Transgene-Assisted Genetic Screen Identifies rsd-6 and Novel Genes as Key Components of Antiviral RNA Interference in Caenorhabditis elegans
Tianyun Long, Fei Meng, Rui Lu
J Virol. 2018 Sep 1; 92(17): e00416-18. Prepublished online 2018 Jun 27. Published online 2018 Aug 16. doi: 10.1128/JVI.00416-18
PMCID:
PMC6096818
AbstractArticlePDF–2.3M
13.
The Antiviral RNA Interference Response Provides Resistance to Lethal Arbovirus Infection and Vertical Transmission in Caenorhabditis elegans
Don B. Gammon, Takao Ishidate, Lichao Li, Weifeng Gu, Neal Silverman, Craig C. Mello
Curr Biol. Author manuscript; available in PMC 2018 Mar 20.
Published in final edited form as: Curr Biol. 2017 Mar 20; 27(6): 795–806. Published online 2017 Mar 2. doi: 10.1016/j.cub.2017.02.004
PMCID:
PMC5446062
AbstractArticlePDF–1.3M
14.
Caenorhabditis elegans RIG-I Homolog Mediates Antiviral RNA Interference Downstream of Dicer-Dependent Biogenesis of Viral Small Interfering RNAs
Stephanie R. Coffman, Jinfeng Lu, Xunyang Guo, Jing Zhong, Hongshan Jiang, Gina Broitman-Maduro, Wan-Xiang Li, Rui Lu, Morris Maduro, Shou-wei Ding
mBio. 2017 Mar-Apr; 8(2): e00264-17. Published online 2017 Mar 21. doi: 10.1128/mBio.00264-17
PMCID:
PMC5362034
AbstractArticlePDF–2.7M
15.
Caenorhabditis elegans ALG-1 antimorphic mutations uncover functions for Argonaute in microRNA guide strand selection and passenger strand disposal
Anna Y. Zinovyeva, Isana Veksler-Lublinsky, Ajay A. Vashisht, James A. Wohlschlegel, Victor R. Ambros
Proc Natl Acad Sci U S A. 2015 Sep 22; 112(38): E5271–E5280. Published online 2015 Sep 8. doi: 10.1073/pnas.1506576112
PMCID:
PMC4586838
AbstractArticlePDF–1.1M
16.
A deletion polymorphism in the Caenorhabditis elegans RIG-I homolog disables viral RNA dicing and antiviral immunity
Alyson Ashe, Tony Bélicard, Jérémie Le Pen, Peter Sarkies, Lise Frézal, Nicolas J Lehrbach, Marie-Anne Félix, Eric A Miska
eLife. 2013; 2: e00994. Published online 2013 Oct 8. doi: 10.7554/eLife.00994
PMCID:
PMC3793227
AbstractArticlePDF–3.9M
17.
Homologous RIG-I–like helicase proteins direct RNAi-mediated antiviral immunity in C. elegans by distinct mechanisms
Xunyang Guo, Rui Zhang, Jeffrey Wang, Shou-Wei Ding, Rui Lu
Proc Natl Acad Sci U S A. 2013 Oct 1; 110(40): 16085–16090. Published online 2013 Sep 16. doi: 10.1073/pnas.1307453110
PMCID:
PMC3791698
AbstractArticlePDF–1.0M
18.
Tudor domain ERI-5 tethers an RNA-dependent RNA polymerase to DCR-1 to potentiate endo-RNAi
Caroline Thivierge, Neetha Makil, Mathieu Flamand, Jessica J. Vasale, Craig C. Mello, James Wohlschlegel, Darryl Conte, Jr., Thomas F. Duchaine
Nat Struct Mol Biol. Author manuscript; available in PMC 2013 Jun 17.
Published in final edited form as: Nat Struct Mol Biol. 2011 Dec 18; 19(1): 90–97. Published online 2011 Dec 18. doi: 10.1038/nsmb.2186
Correction in:
volume 20 on page 244
PMCID:
PMC3684169
AbstractArticlePDF–2.4M
19.
A LIN28-dependent structural change of pre-let-7g directly inhibits Dicer processing
Helen L. Lightfoot, Anthony Bugaut, Javier Armisen, Nicolas J. Lehrbach, Eric A. Miska, Shankar Balasubramanian
Biochemistry. Author manuscript; available in PMC 2012 May 29.
Published in final edited form as: Biochemistry. 2011 Sep 6; 50(35): 7514–7521. Published online 2011 Aug 11. doi: 10.1021/bi200851d
PMCID:
PMC3361669
AbstractArticlePDF–1.5M
20.
Piwi and piRNAs Act Upstream of an Endogenous siRNA Pathway to suppress Tc3 Transposon Mobility in the Caenorhabditis elegans germline
Partha P. Das, Marloes P. Bagijn, Leonard D. Goldstein, Julie R. Woolford, Nicolas J. Lehrbach, Alexandra Sapetschnig, Heeran R. Buhecha, Michael J. Gilchrist, Kevin L. Howe, Rory Stark, Nik Matthews, Eugene Berezikov, René F. Ketting, Simon Tavaré, Eric A. Miska
Mol Cell. Author manuscript; available in PMC 2012 May 16.
Published in final edited form as: Mol Cell. 2008 Jul 11; 31(1): 79–90. Published online 2008 Jun 19. doi: 10.1016/j.molcel.2008.06.003
PMCID:
PMC3353317
AbstractArticlePDF–2.3M

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