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Items: 1 to 20 of 138

1.
Slc12a2 loss in insulin-secreting β-cells links development of overweight and metabolic dysregulation to impaired satiation control of feeding
Yakshkumar Dilipbhai Rathod, Rana Abdelgawad, Christian A. Hübner, Mauricio Di Fulvio
Am J Physiol Endocrinol Metab. 2023 Nov 1; 325(5): E581–E594. Published online 2023 Oct 11. doi: 10.1152/ajpendo.00197.2023
PMCID:
PMC10864024
AbstractArticle
2.
Identification of new ciliary signaling pathways in the brain and insights into neurological disorders
Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz
Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700
PMCID:
PMC10769350
AbstractArticlePDF–11M
3.
In vitro investigation of the effect of proinflammatory cytokines on mouse choroid plexus membrane transporters Ncbe and NKCC1
Laura Øllegaard Johnsen, Kathrine Abildskov Friis, Helle Hasager Damkier
Fluids Barriers CNS. 2023; 20: 71. Published online 2023 Oct 12. doi: 10.1186/s12987-023-00474-9
PMCID:
PMC10568836
AbstractArticlePDF–4.0M
4.
Cell-autonomous and non-cell-autonomous roles of NKCC1 in regulating neural stem cell quiescence in the hippocampal dentate gyrus
Feng Zhang, Kijun Yoon, Nam-Shik Kim, Guo-li Ming, Hongjun Song
Stem Cell Reports. 2023 Jul 11; 18(7): 1468–1481. Published online 2023 Jun 29. doi: 10.1016/j.stemcr.2023.05.021
PMCID:
PMC10362507
AbstractArticlePDF–8.5M
5.
Age-appropriate potassium clearance from perinatal cerebrospinal fluid depends on choroid plexus NKCC1
Ryann M. Fame, Huixin Xu, Aja Pragana, Maria Lehtinen
Fluids Barriers CNS. 2023; 20: 45. Published online 2023 Jun 16. doi: 10.1186/s12987-023-00438-z
PMCID:
PMC10276483
AbstractArticlePDF–2.6M
6.
ZBTB20 is essential for cochlear maturation and hearing in mice
Zhifang Xie, Xian-Hua Ma, Qiu-Fang Bai, Jie Tang, Jian-He Sun, Fei Jiang, Wei Guo, Chen-Ma Wang, Rui Yang, Yin-Chuan Wen, Fang-Yuan Wang, Yu-Xia Chen, Hai Zhang, David Z. He, Matthew W. Kelley, Shiming Yang, Weiping J. Zhang
Proc Natl Acad Sci U S A. 2023 Jun 13; 120(24): e2220867120. Published online 2023 Jun 6. doi: 10.1073/pnas.2220867120
PMCID:
PMC10268240
AbstractArticlePDF–7.7M
7.
Expression patterns of NKCC1 in neurons and non-neuronal cells during cortico-hippocampal development
Samu N Kurki, Pavel Uvarov, Alexey S Pospelov, Kalevi Trontti, Antje K Hübner, Rakenduvadhana Srinivasan, Masahiko Watanabe, Iiris Hovatta, Christian A Hübner, Kai Kaila, Mari A Virtanen
Cereb Cortex. 2023 May 15; 33(10): 5906–5923. Published online 2022 Dec 27. doi: 10.1093/cercor/bhac470
PMCID:
PMC10183754
AbstractArticlePDF–3.1M
8.
Role of NKCC1 and KCC2 during hypoxia-induced neuronal swelling in the neonatal neocortex
Yusuke Takezawa, Rachel Langton, Samuel M. Baule, Miriam Bridget Zimmerman, Stephen Baek, Joseph Glykys
Neurobiol Dis. Author manuscript; available in PMC 2023 Mar 1.
Published in final edited form as: Neurobiol Dis. 2023 Mar; 178: 106013. Published online 2023 Jan 25. doi: 10.1016/j.nbd.2023.106013
PMCID:
PMC9945323
AbstractArticlePDF–2.3M
9.
B cell–intrinsic requirement for WNK1 kinase in antibody responses in mice
Darryl A. Hayward, Lesley Vanes, Stefanie Wissmann, Sujana Sivapatham, Harald Hartweger, Joshua Biggs O’May, Leonard L. de Boer, Richard Mitter, Robert Köchl, Jens V. Stein, Victor L.J. Tybulewicz
J Exp Med. 2023 Mar 6; 220(3): e20211827. Published online 2023 Jan 20. doi: 10.1084/jem.20211827
PMCID:
PMC9872328
AbstractArticlePDF–6.8M
10.
WNK kinases sense molecular crowding and rescue cell volume via phase separation
Cary R. Boyd-Shiwarski, Daniel J. Shiwarski, Shawn E. Griffiths, Rebecca T. Beacham, Logan Norrell, Daryl E. Morrison, Jun Wang, Jacob Mann, William Tennant, Eric N. Anderson, Jonathan Franks, Michael Calderon, Kelly A. Connolly, Muhammad Umar Cheema, Claire J. Weaver, Lubika J. Nkashama, Claire C. Weckerly, Katherine E. Querry, Udai Bhan Pandey, Christopher J. Donnelly, Dandan Sun, Aylin R. Rodan, Arohan R. Subramanya
Cell. Author manuscript; available in PMC 2023 Nov 23.
Published in final edited form as: Cell. 2022 Nov 23; 185(24): 4488–4506.e20. Published online 2022 Oct 31. doi: 10.1016/j.cell.2022.09.042
PMCID:
PMC9699283
AbstractArticlePDF–3.7M
11.
SOX9 and SOX10 control fluid homeostasis in the inner ear for hearing through independent and cooperative mechanisms
Irene Y. Y. Szeto, Daniel K. H. Chu, Peikai Chen, Ka Chi Chu, Tiffany Y. K. Au, Keith K. H. Leung, Yong-Heng Huang, Sarah L. Wynn, Angel C. Y. Mak, Ying-Shing Chan, Wood Yee Chan, Ralf Jauch, Bernd Fritzsch, Mai Har Sham, Robin Lovell-Badge, Kathryn S. E. Cheah
Proc Natl Acad Sci U S A. 2022 Nov 15; 119(46): e2122121119. Published online 2022 Nov 7. doi: 10.1073/pnas.2122121119
PMCID:
PMC9674217
AbstractArticlePDF–2.7M
12.
Impaired neurogenesis alters brain biomechanics in a neuroprogenitor-based genetic subtype of congenital hydrocephalus
Phan Q. Duy, Stefan C. Weise, Claudia Marini, Xiao-Jun Li, Dan Liang, Peter J. Dahl, Shaojie Ma, Ana Spajic, Weilai Dong, Jane Juusola, Emre Kiziltug, Adam J. Kundishora, Sunil Koundal, Maysam Z. Pedram, Lucia A. Torres-Fernández, Kristian Händler, Elena De Domenico, Matthias Becker, Thomas Ulas, Stefan A. Juranek, Elisa Cuevas, Le Thi Hao, Bettina Jux, André M. M. Sousa, Fuchen Liu, Suel-Kee Kim, Mingfeng Li, Yiying Yang, Yutaka Takeo, Alvaro Duque, Carol Nelson-Williams, Yonghyun Ha, Kartiga Selvaganesan, Stephanie M. Robert, Amrita K. Singh, Garrett Allington, Charuta G. Furey, Andrew T. Timberlake, Benjamin C. Reeves, Hannah Smith, Ashley Dunbar, Tyrone DeSpenza, Jr., June Goto, Arnaud Marlier, Andres Moreno-De-Luca, Xin Yu, William E. Butler, Bob S. Carter, Evelyn M. R. Lake, R. Todd Constable, Pasko Rakic, Haifan Lin, Engin Deniz, Helene Benveniste, Nikhil S. Malvankar, Juvianee I. Estrada-Veras, Christopher A. Walsh, Seth L. Alper, Joachim L. Schultze, Katrin Paeschke, Angelika Doetzlhofer, F. Gregory Wulczyn, Sheng Chih Jin, Richard P. Lifton, Nenad Sestan, Waldemar Kolanus, Kristopher T. Kahle
Nat Neurosci. Author manuscript; available in PMC 2022 Nov 15.
Published in final edited form as: Nat Neurosci. 2022 Apr; 25(4): 458–473. Published online 2022 Apr 4. doi: 10.1038/s41593-022-01043-3
PMCID:
PMC9664907
AbstractArticlePDF–6.3M
13.
A subpopulation of agouti-related peptide neurons exciting corticotropin-releasing hormone axon terminals in median eminence led to hypothalamic-pituitary-adrenal axis activation in response to food restriction
Ruksana Yesmin, Miho Watanabe, Adya Saran Sinha, Masaru Ishibashi, Tianying Wang, Atsuo Fukuda
Front Mol Neurosci. 2022; 15: 990803. Published online 2022 Sep 29. doi: 10.3389/fnmol.2022.990803
PMCID:
PMC9557964
AbstractArticlePDF–9.2M
14.
Beta-Amyloid (Aβ1-42) Increases the Expression of NKCC1 in the Mouse Hippocampus
Patricia Lam, Chitra Vinnakota, Beatriz Calvo-Flores Guzmán, Julia Newland, Katie Peppercorn, Warren P. Tate, Henry J. Waldvogel, Richard L. M. Faull, Andrea Kwakowsky
Molecules. 2022 Apr; 27(8): 2440. Published online 2022 Apr 10. doi: 10.3390/molecules27082440
PMCID:
PMC9027496
AbstractArticlePDF–6.5M
15.
The NKCC1 ion transporter modulates microglial phenotype and inflammatory response to brain injury in a cell-autonomous manner
Krisztina Tóth, Nikolett Lénárt, Péter Berki, Rebeka Fekete, Eszter Szabadits, Balázs Pósfai, Csaba Cserép, Ahmad Alatshan, Szilvia Benkő, Dániel Kiss, Christian A. Hübner, Attila Gulyás, Kai Kaila, Zsuzsanna Környei, Ádám Dénes
PLoS Biol. 2022 Jan; 20(1): e3001526. Published online 2022 Jan 27. doi: 10.1371/journal.pbio.3001526
PMCID:
PMC8856735
AbstractArticlePDF–3.8M
16.
Constitutive activation of canonical Wnt signaling disrupts choroid plexus epithelial fate
Arpan Parichha, Varun Suresh, Mallika Chatterjee, Aditya Kshirsagar, Lihi Ben-Reuven, Tsviya Olender, M. Mark Taketo, Velena Radosevic, Mihaela Bobic-Rasonja, Sara Trnski, Michael J. Holtzman, Nataša Jovanov-Milosevic, Orly Reiner, Shubha Tole
Nat Commun. 2022; 13: 633. Published online 2022 Feb 2. doi: 10.1038/s41467-021-27602-z
PMCID:
PMC8810795
AbstractArticlePDF–21M
17.
Restoring neuronal chloride homeostasis with anti-NKCC1 gene therapy rescues cognitive deficits in a mouse model of Down syndrome
Martina Parrini, Shovan Naskar, Micol Alberti, Ilaria Colombi, Giovanni Morelli, Anna Rocchi, Marina Nanni, Federica Piccardi, Severine Charles, Giuseppe Ronzitti, Federico Mingozzi, Andrea Contestabile, Laura Cancedda
Mol Ther. 2021 Oct 6; 29(10): 3072–3092. Published online 2021 May 29. doi: 10.1016/j.ymthe.2021.05.023
PMCID:
PMC8531145
AbstractArticlePDF–3.9M
18.
Compensatory ion transport buffers daily protein rhythms to regulate osmotic balance and cellular physiology
Alessandra Stangherlin, Joseph L. Watson, David C. S. Wong, Silvia Barbiero, Aiwei Zeng, Estere Seinkmane, Sew Peak Chew, Andrew D. Beale, Edward A. Hayter, Alina Guna, Alison J. Inglis, Marrit Putker, Eline Bartolami, Stefan Matile, Nicolas Lequeux, Thomas Pons, Jason Day, Gerben van Ooijen, Rebecca M. Voorhees, David A. Bechtold, Emmanuel Derivery, Rachel S. Edgar, Peter Newham, John S. O’Neill
Nat Commun. 2021; 12: 6035. Published online 2021 Oct 15. doi: 10.1038/s41467-021-25942-4
Correction in:
Nat Commun. 2021; 12: 6988.
PMCID:
PMC8520019
AbstractArticlePDF–2.6M
19.
Oligodendrocytic Na+-K+-Cl– co-transporter 1 activity facilitates axonal conduction and restores plasticity in the adult mouse brain
Yoshihiko Yamazaki, Yoshifumi Abe, Satoshi Fujii, Kenji F. Tanaka
Nat Commun. 2021; 12: 5146. Published online 2021 Aug 26. doi: 10.1038/s41467-021-25488-5
PMCID:
PMC8390751
AbstractArticlePDF–2.9M
20.
A limited role of NKCC1 in telencephalic glutamatergic neurons for developing hippocampal network dynamics and behavior
Jürgen Graf, Chuanqiang Zhang, Stephan Lawrence Marguet, Tanja Herrmann, Tom Flossmann, Robin Hinsch, Vahid Rahmati, Madlen Guenther, Christiane Frahm, Anja Urbach, Ricardo Melo Neves, Otto W. Witte, Stefan J. Kiebel, Dirk Isbrandt, Christian A. Hübner, Knut Holthoff, Knut Kirmse
Proc Natl Acad Sci U S A. 2021 Apr 6; 118(14): e2014784118. Published online 2021 Mar 29. doi: 10.1073/pnas.2014784118
PMCID:
PMC8040628
AbstractArticlePDF–3.2M

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