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Items: 1 to 20 of 31

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Diet-induced induction of hepatic serine/threonine kinase STK38 triggers proinflammation and hepatic lipid accumulation
Priya Rawat, Shilpa Thakur, Surbhi Dogra, Kajal Jaswal, Budheswar Dehury, Prosenjit Mondal
J Biol Chem. 2023 May; 299(5): 104678. Published online 2023 Apr 5. doi: 10.1016/j.jbc.2023.104678
PMCID:
PMC10193238
AbstractArticlePDF–2.9M
3.
Loss of NDR1/2 kinases impairs endomembrane trafficking and autophagy leading to neurodegeneration
Flavia Roşianu, Simeon R Mihaylov, Noreen Eder, Antonie Martiniuc, Suzanne Claxton, Helen R Flynn, Shamsinar Jalal, Marie-Charlotte Domart, Lucy Collinson, Mark Skehel, Ambrosius P Snijders, Matthias Krause, Sharon A Tooze, Sila K Ultanir
Life Sci Alliance. 2023 Feb; 6(2): e202201712. Published online 2022 Nov 29. doi: 10.26508/lsa.202201712
PMCID:
PMC9711861
AbstractArticlePDF–10M
4.
Molecular Mechanism of Biofilm Locator Protein Kinase Dbf2p-related kinase 1 in Regulating Innate Immune Response to Interleukin 17-induced Viral Pneumonia
Haifeng Wang, Lina Bu, Fang Shu, Yun Bai, Feixiao Xue, Shanshan Shi, Daqing Sun
Bioengineered. 2021; 12(2): 10335–10344. Published online 2021 Dec 6. doi: 10.1080/21655979.2021.1996316
PMCID:
PMC8809916
AbstractArticlePDF–943K
5.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
6.
Ndr kinases regulate retinal interneuron proliferation and homeostasis
Hélène Léger, Evelyn Santana, N. Adrian Leu, Eliot T. Smith, William A. Beltran, Gustavo D. Aguirre, Francis C. Luca
Sci Rep. 2018; 8: 12544. Published online 2018 Aug 22. doi: 10.1038/s41598-018-30492-9
PMCID:
PMC6105603
AbstractArticlePDF–2.8M
7.
Downregulated NDR1 protein kinase inhibits innate immune response by initiating an miR146a-STAT1 feedback loop
Zhiyong Liu, Qiang Qin, Cheng Wu, Hui Li, Jia’nan Shou, Yuting Yang, Meidi Gu, Chunmei Ma, Wenlong Lin, Yan Zou, Yuanyuan Zhang, Feng Ma, Jihong Sun, Xiaojian Wang
Nat Commun. 2018; 9: 2789. Published online 2018 Jul 17. doi: 10.1038/s41467-018-05176-7
PMCID:
PMC6050289
AbstractArticlePDF–1.6M
8.
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang
Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626
PMCID:
PMC5381226
AbstractArticlePDF–1.4M
9.
NDR1 protein kinase promotes IL‐17‐ and TNF‐α‐mediated inflammation by competitively binding TRAF3
Chunmei Ma, Wenlong Lin, Zhiyong Liu, Wei Tang, Rahul Gautam, Hui Li, Youcun Qian, He Huang, Xiaojian Wang
EMBO Rep. 2017 Apr; 18(4): 586–602. Published online 2017 Feb 20. doi: 10.15252/embr.201642140
PMCID:
PMC5376972
AbstractArticlePDF–6.1M
10.
Stk38 Modulates Rbm24 Protein Stability to Regulate Sarcomere Assembly in Cardiomyocytes
Jing Liu, Xu Kong, Lee Yew Mun, Zhang Meng Kai, Guo Li Yan, Yu Lin, Teck Kwang Lim, Qingsong Lin, Xiu Qin Xu
Sci Rep. 2017; 7: 44870. Published online 2017 Mar 21. doi: 10.1038/srep44870
Correction in:
Sci Rep. 2017; 7: 46854.
PMCID:
PMC5359592
AbstractArticlePDF–2.0M
11.
The Interleukin-2-mTORc1 Axis Defines the Reciprocal Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells
John P. Ray, Matthew M. Staron, Justin A. Shyer, Ping-Chih Ho, Heather D. Marshall, Simon M. Gray, Brian J. Laidlaw, Koichi Araki, Rafi Ahmed, Susan M. Kaech, Joe Craft
Immunity. Author manuscript; available in PMC 2016 Oct 20.
Published in final edited form as: Immunity. 2015 Oct 20; 43(4): 690–702. Published online 2015 Sep 22. doi: 10.1016/j.immuni.2015.08.017
PMCID:
PMC4618086
AbstractArticlePDF–2.2M
12.
Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin
Xiaolai Zhou, Lirong Sun, Francisco Bastos de Oliveira, Xiaoyang Qi, William J. Brown, Marcus B. Smolka, Ying Sun, Fenghua Hu
J Cell Biol. 2015 Sep 14; 210(6): 991–1002. doi: 10.1083/jcb.201502029
PMCID:
PMC4576858
AbstractArticlePDF–3.0M
13.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
14.
Hdac6 regulates Tip60-p400 function in stem cells
Poshen B Chen, Jui-Hung Hung, Taylor L Hickman, Andrew H Coles, James F Carey, Zhiping Weng, Feixia Chu, Thomas G Fazzio
eLife. 2013; 2: e01557. Published online 2013 Dec 3. doi: 10.7554/eLife.01557
PMCID:
PMC3843111
AbstractArticlePDF–5.7M
15.
Identification of a Novel Link between the Protein Kinase NDR1 and TGFβ Signaling in Epithelial Cells
Isabelle Pot, Shachi Patel, Lili Deng, Amrita Singh Chandhoke, Chi Zhang, Azad Bonni, Shirin Bonni
PLoS One. 2013; 8(6): e67178. Published online 2013 Jun 26. doi: 10.1371/journal.pone.0067178
PMCID:
PMC3694053
AbstractArticlePDF–1.4M
16.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
17.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
18.
MICAL-1 Is a Negative Regulator of MST-NDR Kinase Signaling and Apoptosis
Yeping Zhou, Youri Adolfs, W. W. M. Pim Pijnappel, Stephen J. Fuller, Roel C. Van der Schors, Ka Wan Li, Peter H. Sugden, August B. Smit, Alexander Hergovich, R. Jeroen Pasterkamp
Mol Cell Biol. 2011 Sep; 31(17): 3603–3615. doi: 10.1128/MCB.01389-10
PMCID:
PMC3165550
AbstractArticlePDF–2.1M
19.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
20.
Systematic Characterization of Human Protein Complexes Identifies Chromosome Segregation Proteins
James R.A. Hutchins, Yusuke Toyoda, Björn Hegemann, Ina Poser, Jean-Karim Hériché, Martina M. Sykora, Martina Augsburg, Otto Hudecz, Bettina A. Buschhorn, Jutta Bulkescher, Christian Conrad, David Comartin, Alexander Schleiffer, Mihail Sarov, Andrei Pozniakovsky, Mikolaj Michal Slabicki, Siegfried Schloissnig, Ines Steinmacher, Marit Leuschner, Andrea Ssykor, Steffen Lawo, Laurence Pelletier, Holger Stark, Kim Nasmyth, Jan Ellenberg, Richard Durbin, Frank Buchholz, Karl Mechtler, Anthony A. Hyman, Jan-Michael Peters
Science. Author manuscript; available in PMC 2010 Nov 22.
Published in final edited form as: Science. 2010 Apr 30; 328(5978): 593–599. Published online 2010 Apr 1. doi: 10.1126/science.1181348
PMCID:
PMC2989461
AbstractArticlePDF–2.2M

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