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Select item 108974501.

The CDK Pho85 inhibits Whi7 Start repressor to promote cell cycle entry in budding yeast

Cristina Ros-Carrero, Mihai Spiridon-Bodi, J Carlos Igual, Mercè Gomar-Alba

EMBO Rep. 2024 Feb; 25(2): 745–769. Published online 2024 Jan 17. doi: 10.1038/s44319-023-00049-7

PMCID:: PMC10897450

Abstract Article PDF–7.0M

Select item 108724772.

Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle

Michael J. O’Brien, Athar Ansari

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968

PMCID:: PMC10872477

Abstract Article PDF–1.7M

Select item 107001383.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 102977004.

The Hsp90 molecular chaperone governs client proteins by targeting intrinsically disordered regions

Janhavi A. Kolhe, Neethu L. Babu, Brian C. Freeman

Mol Cell. Author manuscript; available in PMC 2024 Jun 15.

Published in final edited form as: Mol Cell. 2023 Jun 15; 83(12): 2035–2044.e7. Published online 2023 Jun 8. doi: 10.1016/j.molcel.2023.05.021

PMCID:: PMC10297700

Abstract Article PDF–2.0M

Select item 102333685.

A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Nir Cohen, Naama Aviram, Maya Schuldiner

EMBO J. 2023 Jun; 42(11): e113385. Published online 2023 Apr 19. doi: 10.15252/embj.2022113385

PMCID:: PMC10233368

Abstract Article PDF–1.2M

Select item 99741346.

The nutrient-responsive CDK Pho85 primes the Sch9 kinase for its activation by TORC1

Marie-Anne Deprez, Marco Caligaris, Joëlle Rosseels, Riko Hatakeyama, Ruben Ghillebert, Belém Sampaio-Marques, Kaivalya Mudholkar, Elja Eskes, Els Meert, Christian Ungermann, Paula Ludovico, Sabine Rospert, Claudio De Virgilio, Joris Winderickx

PLoS Genet. 2023 Feb; 19(2): e1010641. Published online 2023 Feb 15. doi: 10.1371/journal.pgen.1010641

PMCID:: PMC9974134

Abstract Article PDF–4.7M

Select item 98363487.

A synthetic genetic array screen for interactions with the RNA helicase DED1 during cell stress in budding yeast

Sara B Carey, Hannah M List, Ashwin Siby, Paolo Guerra, Timothy A Bolger

G3 (Bethesda) 2023 Jan; 13(1): jkac296. Published online 2022 Nov 21. doi: 10.1093/g3journal/jkac296

PMCID:: PMC9836348

Abstract Article PDF–857K

Select item 95870058.

Phosphatidic Acid Mediates the Nem1-Spo7/Pah1 Phosphatase Cascade in Yeast Lipid Synthesis

Joanna M. Kwiatek, Bryan Gutierrez, Enver Cagri Izgu, Gil-Soo Han, George M. Carman

J Lipid Res. 2022 Nov; 63(11): 100282. Published online 2022 Sep 20. doi: 10.1016/j.jlr.2022.100282

PMCID:: PMC9587005

Abstract Article PDF–1.8M

Select item 93525569.

Glycogen synthase kinase homolog Rim11 regulates lipid synthesis through the phosphorylation of Pah1 phosphatidate phosphatase in yeast

Shoily Khondker, Joanna M. Kwiatek, Gil-Soo Han, George M. Carman

J Biol Chem. 2022 Aug; 298(8): 102221. Published online 2022 Jul 1. doi: 10.1016/j.jbc.2022.102221

PMCID:: PMC9352556

Abstract Article PDF–2.0M

Select item 920981110.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 793946511.

Methylated PP2A stabilizes Gcn4 to enable a methionine-induced anabolic program

Adhish S. Walvekar, Ganesh Kadamur, Sreesa Sreedharan, Ritu Gupta, Rajalakshmi Srinivasan, Sunil Laxman

J Biol Chem. 2020 Dec 25; 295(52): 18390–18405. Published online 2021 Jan 13. doi: 10.1074/jbc.RA120.014248

PMCID:: PMC7939465

Abstract Article PDF–3.0M

Select item 788696112.

Redundant targeting of Isr1 by two CDKs in mitotic cells.

Emma B. Alme, David P. Toczyski

Curr Genet. Author manuscript; available in PMC 2022 Feb 1.

Published in final edited form as: Curr Genet. 2021 Feb; 67(1): 79–83. Published online 2020 Oct 15. doi: 10.1007/s00294-020-01110-x

PMCID:: PMC7886961

Abstract Article PDF–186K

Select item 734032113.

The kinase Isr1 negatively regulates hexosamine biosynthesis in S. cerevisiae

Emma B. Alme, Erica Stevenson, Nevan J. Krogan, Danielle L. Swaney, David P. Toczyski

PLoS Genet. 2020 Jun; 16(6): e1008840. Published online 2020 Jun 24. doi: 10.1371/journal.pgen.1008840

PMCID:: PMC7340321

Abstract Article PDF–2.8M

Select item 725449214.

Pho85 and PI(4,5)P₂ regulate different lipid metabolic pathways in response to cold

Jose A. Prieto, Francisco Estruch, Isaac Córcoles-Sáez, Maurizio Del Poeta, Robert Rieger, Irene Stenzel, Francisca Randez-Gil

Biochim Biophys Acta Mol Cell Biol Lipids. Author manuscript; available in PMC 2020 May 28.

Published in final edited form as: Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Feb; 1865(2): 158557. Published online 2019 Oct 31. doi: 10.1016/j.bbalip.2019.158557

PMCID:: PMC7254492

Abstract Article PDF–2.0M

Select item 724707915.

Genetic interaction profiles of regulatory kinases differ between environmental conditions and cellular states

Siyu Sun, Anastasia Baryshnikova, Nathan Brandt, David Gresham

Mol Syst Biol. 2020 May; 16(5): e9167. Published online 2020 May 25. doi: 10.15252/msb.20199167

PMCID:: PMC7247079

Abstract Article PDF–2.9M

Select item 706580516.

Multi-kinase control of environmental stress responsive transcription

Kieran Mace, Joanna Krakowiak, Hana El-Samad, David Pincus

PLoS One. 2020; 15(3): e0230246. Published online 2020 Mar 11. doi: 10.1371/journal.pone.0230246

PMCID:: PMC7065805

Abstract Article PDF–4.4M

Select item 700308417.

Identification of the Genetic Requirements for Zinc Tolerance and Toxicity in Saccharomyces cerevisiae

Yun-ying Zhao, Chun-lei Cao, Ying-li Liu, Jing Wang, Jie Li, Shi-yun Li, Yu Deng

G3 (Bethesda) 2020 Feb; 10(2): 479–488. Published online 2019 Dec 13. doi: 10.1534/g3.119.400933

PMCID:: PMC7003084

Abstract Article PDF–2.1M

Select item 689045818.

Cyclin-dependent kinase 5 (CDK5) regulates the circadian clock

Andrea Brenna, Iwona Olejniczak, Rohit Chavan, Jürgen A Ripperger, Sonja Langmesser, Elisabetta Cameroni, Zehan Hu, Claudio De Virgilio, Jörn Dengjel, Urs Albrecht

eLife. 2019; 8: e50925. Published online 2019 Nov 5. doi: 10.7554/eLife.50925