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Select item 89136281.

Deep proteomic profiling unveils arylsulfatase A as a non-alcoholic steatohepatitis inducible hepatokine and regulator of glycemic control

Magdalene K. Montgomery, Jacqueline Bayliss, Shuai Nie, William De Nardo, Stacey N. Keenan, Paula M. Miotto, Hamzeh Karimkhanloo, Cheng Huang, Ralf B. Schittenhelm, Anthony S. Don, Andrew Ryan, Nicholas A. Williamson, Geraldine J. Ooi, Wendy A. Brown, Paul R. Burton, Benjamin L. Parker, Matthew J. Watt

Nat Commun. 2022; 13: 1259. Published online 2022 Mar 10. doi: 10.1038/s41467-022-28889-2

PMCID:: PMC8913628

Abstract Article PDF–3.5M

Select item 82801122.

Substrate reduction therapy for Krabbe disease and metachromatic leukodystrophy using a novel ceramide galactosyltransferase inhibitor

Michael C. Babcock, Christina R. Mikulka, Bing Wang, Sanjay Chandriani, Sundeep Chandra, Yue Xu, Katherine Webster, Ying Feng, Hemanth R. Nelvagal, Alex Giaramita, Bryan K. Yip, Melanie Lo, Xuntian Jiang, Qi Chao, Josh C. Woloszynek, Yuqiao Shen, Shripad Bhagwat, Mark S. Sands, Brett E. Crawford

Sci Rep. 2021; 11: 14486. Published online 2021 Jul 14. doi: 10.1038/s41598-021-93601-1

PMCID:: PMC8280112

Abstract Article PDF–10M

Select item 82276103.

Accumulation of Seminolipid in Sertoli Cells Is Associated with Increased Levels of Reactive Oxygen Species and Male Subfertility: Studies in Aging Arsa Null Male Mice

Kessiri Kongmanas, Arpornrad Saewu, Wongsakorn Kiattiburut, Mark A Baker, Kym F Faull, Dylan Burger, Nongnuj Tanphaichitr

Antioxidants (Basel) 2021 Jun; 10(6): 912. Published online 2021 Jun 4. doi: 10.3390/antiox10060912

PMCID:: PMC8227610

Abstract Article PDF–5.5M

Select item 79387704.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 66741005.

Oligodendroglial Progenitor Cell Therapy Limits Central Neurological Deficits in Mice with Metachromatic Leukodystrophy

Maria I. Givogri, Francesca Galbiati, Stefania Fasano, Stefano Amadio, Laura Perani, Daniela Superchi, Pablo Morana, Ubaldo Del Carro, Sergio Marchesini, Riccardo Brambilla, Lawrence Wrabetz, Ernesto Bongarzone

J Neurosci. 2006 Mar 22; 26(12): 3109–3119. doi: 10.1523/JNEUROSCI.4366-05.2006

PMCID:: PMC6674100

Abstract Article PDF–1.9M

Select item 66731256.

Increasing Sulfatide Synthesis in Myelin-Forming Cells of Arylsulfatase A-Deficient Mice Causes Demyelination and Neurological Symptoms Reminiscent of Human Metachromatic Leukodystrophy

Hariharasubramanian Ramakrishnan, Kerstin Khalaj Hedayati, Renate Lüllmann-Rauch, Carsten Wessig, Simon Ngamli Fewou, Helena Maier, Hans-Hilmar Goebel, Volkmar Gieselmann, Matthias Eckhardt

J Neurosci. 2007 Aug 29; 27(35): 9482–9490. doi: 10.1523/JNEUROSCI.2287-07.2007

PMCID:: PMC6673125

Abstract Article PDF–26M

Select item 66722127.

Sulfatide Storage in Neurons Causes Hyperexcitability and Axonal Degeneration in a Mouse Model of Metachromatic Leukodystrophy

Matthias Eckhardt, Kerstin Khalaj Hedayati, Julika Pitsch, Renate Lüllmann-Rauch, Heinz Beck, Simon Ngamli Fewou, Volkmar Gieselmann

J Neurosci. 2007 Aug 22; 27(34): 9009–9021. doi: 10.1523/JNEUROSCI.2329-07.2007

PMCID:: PMC6672212

Abstract Article PDF–916K

Select item 48177918.

Anti-inflammatory Therapy With Simvastatin Improves Neuroinflammation and CNS Function in a Mouse Model of Metachromatic Leukodystrophy

Axel Stein, Stijn Stroobants, Volkmar Gieselmann, Rudi D'Hooge, Ulrich Matzner

Mol Ther. 2015 Jul; 23(7): 1160–1168. Prepublished online 2015 Apr 21. Published online 2015 May 12. doi: 10.1038/mt.2015.69

PMCID:: PMC4817791

Abstract Article PDF–3.4M

Select item 43737509.

Quantification of sulfatides and lysosulfatides in tissues and body fluids by liquid chromatography-tandem mass spectrometry

Mina Mirzaian, Gertjan Kramer, Ben J. H. M. Poorthuis

J Lipid Res. 2015 Apr; 56(4): 936–943. doi: 10.1194/jlr.M057232

PMCID:: PMC4373750

Abstract Article PDF–478K

Select item 435812710.

Dysfunction of Platelet-derived Growth Factor Receptor α (PDGFRα) Represses the Production of Oligodendrocytes from Arylsulfatase A-deficient Multipotential Neural Precursor Cells

Katarzyna C. Pituch, Ana L. Moyano, Aurora Lopez-Rosas, Felecia M. Marottoli, Guannan Li, Chenqi Hu, Richard van Breemen, Jan E. Månsson, Maria I. Givogri

J Biol Chem. 2015 Mar 13; 290(11): 7040–7053. Published online 2015 Jan 20. doi: 10.1074/jbc.M115.636498

PMCID:: PMC4358127

Abstract Article PDF–2.1M

Select item 353977111.

Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells

Hao Wu, Ana C. D’Alessio, Shinsuke Ito, Kai Xia, Zhibin Wang, Kairong Cui, Keji Zhao, Yi Eve Sun, Yi Zhang

Nature. Author manuscript; available in PMC 2013 Jan 8.

Published in final edited form as: Nature. 2011 May 19; 473(7347): 389–393. Published online 2011 Mar 30. doi: 10.1038/nature09934

PMCID:: PMC3539771

Abstract Article PDF–2.7M

Select item 344312812.

Brain conditioning is instrumental for successful microglia reconstitution following hematopoietic stem cell transplantation

Alessia Capotondo, Rita Milazzo, Letterio Salvatore Politi, Angelo Quattrini, Alessio Palini, Tiziana Plati, Stefania Merella, Alessandro Nonis, Clelia di Serio, Eugenio Montini, Luigi Naldini, Alessandra Biffi

Proc Natl Acad Sci U S A. 2012 Sep 11; 109(37): 15018–15023. Published online 2012 Aug 23. doi: 10.1073/pnas.1205858109

PMCID:: PMC3443128

Abstract Article PDF–1.1M

Select item 322028713.

Arylsulfatase A deficiency causes seminolipid accumulation and a lysosomal storage disorder in Sertoli cells

Hongbin Xu, Kessiri Kongmanas, Suraj Kadunganattil, Charles E. Smith, Tony Rupar, Naoko Goto-Inoue, Louis Hermo, Kym F. Faull, Nongnuj Tanphaichitr

J Lipid Res. 2011 Dec; 52(12): 2187–2197. doi: 10.1194/jlr.M019661

PMCID:: PMC3220287

Abstract Article PDF–2.0M

Select item 317805914.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 312991415.

Extracellular pyrophosphate metabolism and calcification in vascular smooth muscle

Ricardo Villa-Bellosta, Xiaonan Wang, José Luis Millán, George R. Dubyak, W. Charles O'Neill

Am J Physiol Heart Circ Physiol. 2011 Jul; 301(1): H61–H68. Published online 2011 Apr 13. doi: 10.1152/ajpheart.01020.2010

PMCID:: PMC3129914

Abstract Article

Select item 302253416.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 266658917.

Saposin B-dependent Reconstitution of Arylsulfatase A Activity in Vitro and in Cell Culture Models of Metachromatic Leukodystrophy

Ulrich Matzner, Bernadette Breiden, Günter Schwarzmann, Afshin Yaghootfam, Arvan L. Fluharty, Andrej Hasilik, Konrad Sandhoff, Volkmar Gieselmann

J Biol Chem. 2009 Apr 3; 284(14): 9372–9381. doi: 10.1074/jbc.M809457200

PMCID:: PMC2666589

Abstract Article PDF–424K

Select item 248821718.

Presence of Arylsulfatase A and Sulfogalactosylglycerolipid in Mouse Ovaries: Localization to the Corpus Luteum

Araya Anupriwan, Matthias Schenk, Kessiri Kongmanas, Rapeepun Vanichviriyakit, Daniela Costa Santos, Arman Yaghoubian, Fang Liu, Alexander Wu, Trish Berger, Kym F. Faull, Porncharn Saitongdee, Prapee Sretarugsa, Nongnuj Tanphaichitr

Endocrinology. 2008 Aug; 149(8): 3942–3951. Published online 2008 Apr 17. doi: 10.1210/en.2008-0281

PMCID:: PMC2488217

Abstract Article

Select item 141356819.

BGEM: An In Situ Hybridization Database of Gene Expression in the Embryonic and Adult Mouse Nervous System

Susan Magdaleno, Patricia Jensen, Craig L Brumwell, Anna Seal, Karen Lehman, Andrew Asbury, Tony Cheung, Tommie Cornelius, Diana M Batten, Christopher Eden, Shannon M Norland, Dennis S Rice, Nilesh Dosooye, Sundeep Shakya, Perdeep Mehta, Tom Curran

PLoS Biol. 2006 Apr; 4(4): e86. Published online 2006 Mar 28. doi: 10.1371/journal.pbio.0040086

PMCID:: PMC1413568

Article PDF–99K

Select item 136911320.

Sulphatase activities are regulated by the interaction of sulphatase-modifying factor 1 with SUMF2

Ester Zito, Alessandro Fraldi, Stefano Pepe, Ida Annunziata, Gary Kobinger, Paola Di Natale, Andrea Ballabio, Maria Pia Cosma

EMBO Rep. 2005 Jul; 6(7): 655–660. Published online 2005 Jun 17. doi: 10.1038/sj.embor.7400454

Correction in:: EMBO Rep. 2016 Dec; 17(12): 1901.

PMCID:: PMC1369113

Abstract Article PDF–182K

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