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Items: 1 to 20 of 500

1.
A MyD88/IL-1R axis regulates PD-1 expression on tumor-associated macrophages and sustains their immunosuppressive function in melanoma
Sarang Tartey, Geoffrey Neale, Peter Vogel, R.K. Subbarao Malireddi, Thirumala-Devi Kanneganti
Cancer Res. Author manuscript; available in PMC 2024 Dec 13.
Published in final edited form as: Cancer Res. 2021 May 1; 81(9): 2358–2372. Published online 2021 Feb 22. doi: 10.1158/0008-5472.CAN-20-3510
PMCID:
PMC11645125
AbstractArticlePDF–3.4M
2.
Opposing tumor-cell-intrinsic and -extrinsic roles of the IRF1 transcription factor in antitumor immunity
Prabhat K. Purbey, Joowon Seo, Manash K. Paul, Keisuke S. Iwamoto, Allison E. Daly, An-Chieh Feng, Ameya S. Champhekar, Justin Langerman, Katie M. Campbell, Dörthe Schaue, William H. McBride, Steven M. Dubinett, Antoni Ribas, Stephen T. Smale, Philip O. Scumpia
Cell Rep. Author manuscript; available in PMC 2024 Aug 9.
Published in final edited form as: Cell Rep. 2024 Jun 25; 43(6): 114289. Published online 2024 Jun 2. doi: 10.1016/j.celrep.2024.114289
PMCID:
PMC11315447
AbstractArticlePDF–3.3M
3.
The AHR repressor limits expression of antimicrobial genes but not AHR-dependent genes in intestinal eosinophils
Heike Weighardt, Michael Shapiro, Michelle Mayer, Irmgard Förster, Brigitta Stockinger, Nicola Laura Diny
J Leukoc Biol. 2024 Aug; 116(2): 369–378. Published online 2024 May 3. doi: 10.1093/jleuko/qiae105
PMCID:
PMC11271977
AbstractArticlePDF–1.1M
4.
Statin prevents cancer development in chronic inflammation by blocking interleukin 33 expression
Jong Ho Park, Mahsa Mortaja, Heehwa G. Son, Xutu Zhao, Lauren M. Sloat, Marjan Azin, Jun Wang, Michael R. Collier, Krishna S. Tummala, Anna Mandinova, Nabeel Bardeesy, Yevgeniy R. Semenov, Mari Mino-Kenudson, Shadmehr Demehri
Nat Commun. 2024; 15: 4099. Published online 2024 May 30. doi: 10.1038/s41467-024-48441-8
PMCID:
PMC11139893
AbstractArticlePDF–2.6M
5.
ZBP1 and TRIF trigger lethal necroptosis in mice lacking caspase-8 and TNFR1
Margaret Solon, Nianfeng Ge, Shannon Hambro, Susan Haller, Jian Jiang, Miriam Baca, Jessica Preston, Allie Maltzman, Katherine E. Wickliffe, Yuxin Liang, Rohit Reja, Dorothee Nickles, Kim Newton, Joshua D. Webster
Cell Death Differ. 2024 May; 31(5): 672–682. Published online 2024 Mar 28. doi: 10.1038/s41418-024-01286-6
PMCID:
PMC11093969
AbstractArticlePDF–5.5M
6.
TRIF-IFN-I pathway in Helicobacter-induced gastric cancer in an accelerated murine disease model and patient biopsies
Prerna Bali, Ivonne Lozano-Pope, Jonathan Hernandez, Monica V. Estrada, Maripat Corr, Michael A. Turner, Michael Bouvet, Christopher Benner, Marygorret Obonyo
iScience. 2024 Apr 19; 27(4): 109457. Published online 2024 Mar 8. doi: 10.1016/j.isci.2024.109457
PMCID:
PMC10981133
AbstractArticlePDF–6.4M
7.
Early cellular mechanisms of type I interferon-driven susceptibility to tuberculosis
Dmitri I. Kotov, Ophelia V. Lee, Stefan A. Fattinger, Charlotte A. Langner, Jaresley V. Guillen, Joshua M. Peters, Andres Moon, Eileen M. Burd, Kristen C. Witt, Daniel B. Stetson, David L. Jaye, Bryan D. Bryson, Russell E. Vance
Cell. Author manuscript; available in PMC 2023 Dec 30.
Published in final edited form as: Cell. 2023 Dec 7; 186(25): 5536–5553.e22. Published online 2023 Nov 28. doi: 10.1016/j.cell.2023.11.002
PMCID:
PMC10757650
AbstractArticlePDF–3.3M
8.
Genetic and immune determinants of E. coli liver abscess formation
Karthik Hullahalli, Katherine G. Dailey, Yuko Hasegawa, Encarnacion Torres, Masataka Suzuki, Hailong Zhang, David W. Threadgill, Victor M. Navarro, Matthew K. Waldor
Proc Natl Acad Sci U S A. 2023 Dec 19; 120(51): e2310053120. Published online 2023 Dec 14. doi: 10.1073/pnas.2310053120
PMCID:
PMC10743367
AbstractArticlePDF–4.4M
9.
TLR4 Is a Negative Regulator in Noninfectious Lung Inflammation
Hang Zhao, Shaw-Wei Leu, Liyun Shi, Rejmon Dedaj, Gaofeng Zhao, Hari G. Garg, Lianjun Shen, Egil Lien, Katherine A. Fitzgerald, Aviva Shiedlin, Huahao Shen, Deborah A. Quinn, Charles A. Hales
J Immunol. Author manuscript; available in PMC 2023 Dec 21.
Published in final edited form as: J Immunol. 2010 May 1; 184(9): 5308–5314. Published online 2010 Mar 31. doi: 10.4049/jimmunol.1000009
PMCID:
PMC10733842
AbstractArticlePDF–1.3M
10.
Akkermansia muciniphila induces slow extramedullary hematopoiesis via cooperative IL‐1R/TLR signals
Yuxin Wang, Tatsuya Morishima, Maiko Sezaki, Ryo Sato, Gaku Nakato, Shinji Fukuda, Kouji Kobiyama, Ken J Ishii, Yuhua Li, Hitoshi Takizawa
EMBO Rep. 2023 Dec; 24(12): e57485. Published online 2023 Oct 23. doi: 10.15252/embr.202357485
PMCID:
PMC10702838
AbstractArticlePDF–4.4M
11.
Ethanol Induces Neuroinflammation in a Chronic Plus Binge Mouse Model of Alcohol Use Disorder via TLR4 and MyD88-Dependent Signaling
Kalee N. Holloway, James C. Douglas, Tonya M. Rafferty, Cynthia J. M. Kane, Paul D. Drew
Cells. 2023 Aug; 12(16): 2109. Published online 2023 Aug 21. doi: 10.3390/cells12162109
PMCID:
PMC10453365
AbstractArticlePDF–2.2M
12.
MAVS signaling is required for preventing persistent chikungunya heart infection and chronic vascular tissue inflammation
Maria G. Noval, Sophie N. Spector, Eric Bartnicki, Franco Izzo, Navneet Narula, Stephen T. Yeung, Payal Damani-Yokota, M. Zahidunnabi Dewan, Valeria Mezzano, Bruno A. Rodriguez-Rodriguez, Cynthia Loomis, Kamal M. Khanna, Kenneth A. Stapleford
Nat Commun. 2023; 14: 4668. Published online 2023 Aug 3. doi: 10.1038/s41467-023-40047-w
PMCID:
PMC10400619
AbstractArticlePDF–5.1M
13.
Activation of regulatory dendritic cells by Mertk coincides with a temporal wave of apoptosis in neonatal lungs
Aaron Silva–Sanchez, Selene Meza–Perez, Mingyong Liu, Sara L Stone, Leopoldo Flores–Romo, Eric Ubil, Frances E. Lund, Alexander F. Rosenberg, Troy D. Randall
Sci Immunol. Author manuscript; available in PMC 2023 Dec 23.
Published in final edited form as: Sci Immunol. 2023 Jun 23; 8(84): eadc9081. Published online 2023 Jun 16. doi: 10.1126/sciimmunol.adc9081
PMCID:
PMC10351240
AbstractArticlePDF–1.7M
14.
A tissue injury sensing and repair pathway distinct from host pathogen defense
Siqi Liu, Yun Ha Hur, Xin Cai, Qian Cong, Yihao Yang, Chiwei Xu, Angelina M. Bilate, Kevin Andrew Uy Gonzales, S. Martina Parigi, Christopher J. Cowley, Brian Hurwitz, Ji-Dung Luo, Tiffany Tseng, Shiri Gur-Cohen, Megan Sribour, Tatiana Omelchenko, John Levorse, Hilda Amalia Pasolli, Craig B. Thompson, Daniel Mucida, Elaine Fuchs
Cell. Author manuscript; available in PMC 2023 Jul 5.
Published in final edited form as: Cell. 2023 May 11; 186(10): 2127–2143.e22. Published online 2023 Apr 24. doi: 10.1016/j.cell.2023.03.031
PMCID:
PMC10321318
AbstractArticlePDF–2.7M
15.
Alpha synuclein, the culprit in Parkinson disease, is required for normal immune function
Md Masud Alam, Yang De, Xiao-Qing Li, Jia Liu, Timothy Carrel Back, Anna Trivett, Baktiar Karim, Denise Barbut, Michael Zasloff, Joost J. Oppenheim
Cell Rep. Author manuscript; available in PMC 2023 Jun 12.
Published in final edited form as: Cell Rep. 2022 Jan 11; 38(2): 110090. doi: 10.1016/j.celrep.2021.110090
PMCID:
PMC10258816
AbstractArticlePDF–1.6M
16.
Innate and adaptive immunity to transfused allogenic red blood cells in mice requires MyD88
Arielle Soldatenko, Laura R. Hoyt, Lan Xu, Samuele Calabro, Steven M. Lewis, Antonia E. Gallman, Krystalyn E. Hudson, Sean R. Stowell, Chance J. Luckey, James C. Zimring, Dong Liu, Manjula Santhanakrishnan, Jeanne E. Hendrickson, Stephanie C. Eisenbarth
J Immunol. Author manuscript; available in PMC 2023 Apr 17.
Published in final edited form as: J Immunol. 2022 Feb 15; 208(4): 991–997. Published online 2022 Jan 17. doi: 10.4049/jimmunol.2100784
PMCID:
PMC10107373
AbstractArticlePDF–1.6M
17.
A p53-TLR3 axis ameliorates pulmonary hypertension by inducing BMPR2 via IRF3
Aneel R. Bhagwani, Mehboob Ali, Bryce Piper, Mingjun Liu, Jaylen Hudson, Neil Kelly, Srimathi Bogamuwa, Hu Yang, James D. Londino, Joseph S. Bednash, Daniela Farkas, Rama K. Mallampalli, Mark R. Nicolls, John J. Ryan, A.A. Roger Thompson, Stephen Y. Chan, Delphine Gomez, Elena A. Goncharova, Laszlo Farkas
iScience. 2023 Feb 17; 26(2): 105935. Published online 2023 Jan 5. doi: 10.1016/j.isci.2023.105935
PMCID:
PMC9852960
AbstractArticlePDF–6.8M
18.
MyD88-dependent signaling drives toll-like receptor-induced trained immunity in macrophages
Allison M. Owen, Liming Luan, Katherine R. Burelbach, Margaret A. McBride, Cody L. Stothers, Olivia A. Boykin, Kalkena Sivanesam, Jessica F. Schaedel, Tazeen K. Patil, Jingbin Wang, Antonio Hernandez, Naeem K. Patil, Edward R. Sherwood, Julia K. Bohannon
Front Immunol. 2022; 13: 1044662. Published online 2022 Nov 11. doi: 10.3389/fimmu.2022.1044662
PMCID:
PMC9692127
AbstractArticlePDF–17M
19.
Bacterial polyphosphates induce CXCL4 and synergize with complement anaphylatoxin C5a in lung injury
Julian Roewe, Sarah Walachowski, Arjun Sharma, Kayleigh A. Berthiaume, Christoph Reinhardt, Markus Bosmann
Front Immunol. 2022; 13: 980733. Published online 2022 Nov 3. doi: 10.3389/fimmu.2022.980733
PMCID:
PMC9669059
AbstractArticlePDF–6.6M
20.
The Th1/Tfh-like biased responses elicited by the rASP-1 innate adjuvant are dependent on TRIF and Type I IFN receptor pathways
Parakkal Jovvian George, Radu Marches, Djamel Nehar-Belaid, Jacques Banchereau, Sara Lustigman
Front Immunol. 2022; 13: 961094. Published online 2022 Sep 2. doi: 10.3389/fimmu.2022.961094
PMCID:
PMC9478378
AbstractArticlePDF–2.6M

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