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Items: 1 to 20 of 129

1.
ERRFI1 exacerbates hepatic ischemia reperfusion injury by promoting hepatocyte apoptosis and ferroptosis in a GRB2-dependent manner
Hang Zhao, Huizi Mao
Mol Med. 2024; 30: 82. Published online 2024 Jun 11. doi: 10.1186/s10020-024-00837-4
PMCID:
PMC11167874
AbstractArticlePDF–18M
2.
GRB2 stabilizes RAD51 at reversed replication forks suppressing genomic instability and innate immunity against cancer
Zu Ye, Shengfeng Xu, Yin Shi, Xueqian Cheng, Yuan Zhang, Sunetra Roy, Sarita Namjoshi, Michael A. Longo, Todd M. Link, Katharina Schlacher, Guang Peng, Dihua Yu, Bin Wang, John A. Tainer, Zamal Ahmed
Nat Commun. 2024; 15: 2132. Published online 2024 Mar 8. doi: 10.1038/s41467-024-46283-y
PMCID:
PMC10923831
AbstractArticlePDF–3.7M
3.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
4.
Hepatocyte-specific Wtap deficiency promotes hepatocellular carcinoma by activating GRB2–ERK depending on downregulation of proteasome-related genes
Xinzhi Li, Chunhong Liu, Zhimin Zhang, Xueying Li, Zhicheng Yao, Yanbin Dong, Xin Wang, Zheng Chen
J Biol Chem. 2023 Nov; 299(11): 105301. Published online 2023 Sep 28. doi: 10.1016/j.jbc.2023.105301
PMCID:
PMC10630636
AbstractArticlePDF–2.9M
5.
FRS2-independent GRB2 interaction with FGFR2 is not required for embryonic development
James F. Clark, Philippe Soriano
Biol Open. 2023 Jul 15; 12(7): bio059942. Published online 2023 Jul 27. doi: 10.1242/bio.059942
PMCID:
PMC10399203
AbstractArticlePDF–6.3M
6.
KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility
Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao
Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5
PMCID:
PMC10307852
AbstractArticlePDF–8.8M
7.
GRB2 promotes thymocyte positive selection by facilitating THEMIS-mediated inactivation of SHP1
Seeyoung Choi, Teri Hatzihristidis, Guillaume Gaud, Avik Dutta, Jan Lee, Awadhesh Arya, Lauren M. Clubb, Daniel B. Stamos, Adrienn Markovics, Katalin Mikecz, Paul Love
J Exp Med. 2023 Jul 3; 220(7): e20221649. Published online 2023 Apr 17. doi: 10.1084/jem.20221649
PMCID:
PMC10114920
AbstractArticlePDF–4.4M
8.
Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins
Benjamin Lang, Jae-Seong Yang, Mireia Garriga-Canut, Silvia Speroni, Moritz Aschern, Maria Gili, Tobias Hoffmann, Gian Gaetano Tartaglia, Sebastian P Maurer
Nucleic Acids Res. 2021 Jul 9; 49(12): 6702–6721. Published online 2021 Jun 16. doi: 10.1093/nar/gkab490
PMCID:
PMC8266617
AbstractArticlePDF–4.0M
9.
Prenatal correction of IGF2 to rescue the growth phenotypes in mouse models of Beckwith-Wiedemann and Silver-Russell syndromes
Ji Liao, Tie-Bo Zeng, Nicholas Pierce, Diana A. Tran, Purnima Singh, Jeffrey R. Mann, Piroska E. Szabó
Cell Rep. Author manuscript; available in PMC 2021 Mar 17.
Published in final edited form as: Cell Rep. 2021 Feb 9; 34(6): 108729. doi: 10.1016/j.celrep.2021.108729
PMCID:
PMC7968144
AbstractArticlePDF–1.7M
10.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
11.
Role of long noncoding RNA MEG3/miR-378/GRB2 axis in neuronal autophagy and neurological functional impairment in ischemic stroke
Hong-Cheng Luo, Ting-Zhuang Yi, Fu-Gao Huang, Ying Wei, Xiao-Peng Luo, Qi-Sheng Luo
J Biol Chem. 2020 Oct 9; 295(41): 14125–14139. Published online 2020 Jun 29. doi: 10.1074/jbc.RA119.010946
PMCID:
PMC7549047
AbstractArticlePDF–2.5M
12.
Long noncoding RNA AC092171.4 promotes hepatocellular carcinoma progression by sponging microRNA-1271 and upregulating GRB2
Chengjun Sun, Shanzhou Huang, Yuchen Hou, Zhongqiu Li, Dongmei Xia, Lishan Zhang, Yixi Zhang, Yifeng Cai, Ziming Wang, Qi Zhou, Xiaoshun He, Linwei Wu
Aging (Albany NY) 2020 Jul 31; 12(14): 14141–14156. Published online 2020 Jul 21. doi: 10.18632/aging.103419
PMCID:
PMC7425487
AbstractArticlePDF–2.9M
13.
Quantitative interactomics in primary T cells unveils TCR signal diversification extent and dynamics
Guillaume Voisinne, Kristof Kersse, Karima Chaoui, Liaoxun Lu, Julie Chaix, Lichen Zhang, Marisa Goncalves Menoita, Laura Girard, Youcef Ounoughene, Hui Wang, Odile Burlet-Schiltz, Hervé Luche, Frédéric Fiore, Marie Malissen, Anne Gonzalez de Peredo, Yinming Liang, Romain Roncagalli, Bernard Malissen
Nat Immunol. Author manuscript; available in PMC 2020 Apr 7.
Published in final edited form as: Nat Immunol. 2019 Nov 1; 20(11): 1530–1541. Published online 2019 Oct 7. doi: 10.1038/s41590-019-0489-8
PMCID:
PMC6859066
AbstractArticlePDF–2.9M
14.
The multi-site docking protein Grb2-associated binder 1 (Gab1) enhances interleukin-6-induced MAPK-pathway activation in an SHP2-, Grb2-, and time-dependent manner
Hannes Bongartz, Karen Gille, Wiebke Hessenkemper, Katharina Mandel, Marc Lewitzky, Stephan M. Feller, Fred Schaper
Cell Commun Signal. 2019; 17: 135. Published online 2019 Oct 24. doi: 10.1186/s12964-019-0451-2
PMCID:
PMC6814103
AbstractArticlePDF–3.8M
15.
Interplay between HGAL and Grb2 proteins regulates B-cell receptor signaling
Xiaoyu Jiang, Xiaoqing Lu, Yu Zhang, Leda Lacaria, Brett J. Schuchardt, David C. Mikles, Marco Magistri, Idoia García-Ramírez, Isidro Sanchez-Garcia, Amjad Farooq, Ramiro E. Verdun, Midhat H. Abdulreda, Vincent T. Moy, Izidore S. Lossos
Blood Adv. 2019 Aug 13; 3(15): 2286–2297. Published online 2019 Jul 30. doi: 10.1182/bloodadvances.2018016162
PMCID:
PMC6693015
AbstractArticlePDF–2.3M
16.
Hepatocyte Growth Factor Regulates Migration of Olfactory Interneuron Precursors in the Rostral Migratory Stream through Met–Grb2 Coupling
Donatella Garzotto, Paolo Giacobini, Tiziana Crepaldi, Aldo Fasolo, Silvia De Marchis
J Neurosci. 2008 Jun 4; 28(23): 5901–5909. doi: 10.1523/JNEUROSCI.1083-08.2008
PMCID:
PMC6670326
AbstractArticlePDF–412K
17.
New roles for the de-ubiquitylating enzyme OTUD4 in an RNA–protein network and RNA granules
Richa Das, Lukas Schwintzer, Stanislav Vinopal, Eva Aguado Roca, Marc Sylvester, Ana-Maria Oprisoreanu, Susanne Schoch, Frank Bradke, Meike Broemer
J Cell Sci. 2019 Jun 15; 132(12): jcs229252. Published online 2019 Jun 17. doi: 10.1242/jcs.229252
PMCID:
PMC6602300
AbstractArticle
18.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
19.
USP22 controls multiple signaling pathways that are essential for vasculature formation in the mouse placenta
Evangelia Koutelou, Li Wang, Andria C. Schibler, Hsueh-Ping Chao, Xianghong Kuang, Kevin Lin, Yue Lu, Jianjun Shen, Collene R. Jeter, Andrew Salinger, Marenda Wilson, Yi Chun Chen, Boyko S. Atanassov, Dean G. Tang, Sharon Y. R. Dent
Development. 2019 Feb 15; 146(4): dev174037. Published online 2019 Feb 22. doi: 10.1242/dev.174037
PMCID:
PMC6398448
AbstractArticle
20.
ATG5 is required for B cell polarization and presentation of particulate antigens
Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros
Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327
PMCID:
PMC6333460
AbstractArticlePDF–2.7M

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