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Select item 99934571.

Signals from the TAFA4-PTEN-PU.1 axis alleviate nasal allergy by modulating the expression of FcεRI in mast cells

Caijie Zhou, Meihua Li, Yu Liu, Xinxin Wang, Shuang Zhang, Li Guan, Jingyi Hong, Wei Zhou, Gaohui Wu, Weiliang Diao, Qinmiao Huang, Pingchang Yang

Clin Exp Immunol. 2023 Jan; 211(1): 15–22. Published online 2022 Nov 11. doi: 10.1093/cei/uxac097

PMCID:: PMC9993457

Abstract Article PDF–1.7M

Select item 99075352.

FAM19A4/miR124-2 Methylation Testing and Human Papillomavirus (HPV) 16/18 Genotyping in HPV-Positive Women Under the Age of 30 Years

Frederique J Vink, Chris J L M Meijer, Albertus T Hesselink, Arno N Floore, Birgit I Lissenberg-Witte, Jesper H Bonde, Helle Pedersen, Kate Cuschieri, Ramya Bhatia, Mario Poljak, Anja Oštrbenk Valenčak, Peter Hillemanns, Wim G V Quint, Marta del Pino, Gemma G Kenter, Renske D M Steenbergen, Daniëlle A M Heideman, Maaike C G Bleeker

Clin Infect Dis. 2023 Feb 1; 76(3): e827–e834. Published online 2022 Jun 10. doi: 10.1093/cid/ciac433

PMCID:: PMC9907535

Abstract Article PDF–509K

Select item 94992923.

Full genotyping and FAM19A4/miR124-2 methylation analysis in high-risk human papillomavirus–positive samples from women over 30 years participating in cervical cancer screening in Örebro, Sweden

Malin Kaliff, Gabriella Lillsunde Larsson, Gisela Helenius, Mats G. Karlsson, Lovisa Bergengren

PLoS One. 2022; 17(9): e0274825. Published online 2022 Sep 22. doi: 10.1371/journal.pone.0274825

PMCID:: PMC9499292

Abstract Article PDF–1.0M

Select item 94625364.

Clinical Regression of High-Grade Cervical Intraepithelial Neoplasia Is Associated With Absence of FAM19A4/miR124-2 DNA Methylation (CONCERVE Study)

Wieke W. Kremer, Stèfanie Dick, Daniëlle A.M. Heideman, Renske D.M. Steenbergen, Maaike C.G. Bleeker, Harold R. Verhoeve, W. Marchien van Baal, Nienke van Trommel, Gemma G. Kenter, Chris J.L.M. Meijer, Johannes Berkhof

J Clin Oncol. 2022 Sep 10; 40(26): 3037–3046. Published online 2022 May 5. doi: 10.1200/JCO.21.02433

PMCID:: PMC9462536

Abstract Article PDF–574K

Select item 87706385.

Risk-stratification of HPV-positive women with low-grade cytology by FAM19A4/miR124-2 methylation and HPV genotyping

Stèfanie Dick, Frederique J. Vink, Daniëlle A. M. Heideman, Birgit I. Lissenberg-Witte, Chris J. L. M. Meijer, Johannes Berkhof

Br J Cancer. 2022 Feb 1; 126(2): 259–264. Published online 2021 Nov 6. doi: 10.1038/s41416-021-01614-4

PMCID:: PMC8770638

Abstract Article PDF–872K

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 77562777.

Methylation markers FAM19A4 and miR124‐2 as triage strategy for primary human papillomavirus screen positive women: A large European multicenter study

Jesper Bonde, Arno Floore, Ditte Ejegod, Frederique J. Vink, Albertus Hesselink, Peter M. van de Ven, Anja Oštrbenk Valenčak, Helle Pedersen, Saskia Doorn, Wim G. Quint, Karl Ulrich Petry, Mario Poljak, Grazyna Stanczuk, Kate Cuschieri, Silvia de Sanjosé, Maaike Bleeker, Johannes Berkhof, Chris J. L. M. Meijer, Daniëlle A. M. Heideman

Int J Cancer. 2021 Jan 15; 148(2): 396–405. Published online 2020 Oct 21. doi: 10.1002/ijc.33320

PMCID:: PMC7756277

Abstract Article PDF–772K

Select item 73839008.

FAM19A4/miR124‐2 methylation in invasive cervical cancer: A retrospective cross‐sectional worldwide study

Frederique J. Vink, Chris J.L.M. Meijer, Gary M. Clifford, Mario Poljak, Anja Oštrbenk, Karl Ulrich Petry, Beate Rothe, Jesper Bonde, Helle Pedersen, Silvia de Sanjosé, Montserrat Torres, Marta del Pino, Wim G.V. Quint, Kate Cuschieri, Elia Alcañiz Boada, Nienke E. van Trommel, Birgit I. Lissenberg‐Witte, Arno N. Floore, Albertus T. Hesselink, Renske D.M. Steenbergen, Maaike C.G. Bleeker, Daniëlle A.M. Heideman

Int J Cancer. 2020 Aug 15; 147(4): 1215–1221. Published online 2019 Sep 9. doi: 10.1002/ijc.32614

PMCID:: PMC7383900

Abstract Article PDF–915K

Select item 71318539.

Expression of p16 and HPV E4 on biopsy samples and methylation of FAM19A4 and miR124‐2 on cervical cytology samples in the classification of cervical squamous intraepithelial lesions

Annemiek Leeman, David Jenkins, Marta del Pino, Jaume Ordi, Aureli Torné, John Doorbar, Chris J. L. M. Meijer, Folkert J. van Kemenade, Wim G. V. Quint

Cancer Med. 2020 Apr; 9(7): 2454–2461. Published online 2020 Feb 5. doi: 10.1002/cam4.2855

PMCID:: PMC7131853

Abstract Article PDF–212K

Select item 679158810.

The use of molecular markers for cervical screening of women living with HIV in South Africa

Wieke W. Kremer, Marjolein van Zummeren, Erika Breytenbach, Karin L. Richter, Renske D.M. Steenbergen, Chris J.L.M. Meijer, Greta Dreyer

AIDS. 2019 Nov 1; 33(13): 2035–2042. Published online 2019 Aug 2. doi: 10.1097/QAD.0000000000002325

PMCID:: PMC6791588

Abstract Article PDF–635K

Select item 626304911.

The clinical significance of FAM19A4 methylation in high-risk HPV-positive cervical samples for the detection of cervical (pre)cancer in Chinese women

Qiaowen Bu, Sanfeng Wang, Jian Ma, Xiangcheng Zhou, Guiying Hu, Hua Deng, Xiaoli Sun, Xiaoshan Hong, Hengying Wu, Liang Zhang, Xiping Luo

BMC Cancer. 2018; 18: 1182. Published online 2018 Nov 29. doi: 10.1186/s12885-018-4877-5

PMCID:: PMC6263049

Abstract Article PDF–1.1M

Select item 553161112.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 499754213.

FAM19A4 methylation analysis in self-samples compared with cervical scrapes for detecting cervical (pre)cancer in HPV-positive women

Roosmarijn Luttmer, Lise M A De Strooper, Maaike G Dijkstra, Johannes Berkhof, Peter J F Snijders, Renske D M Steenbergen, Folkert J van Kemenade, Lawrence Rozendaal, Theo J M Helmerhorst, René H M Verheijen, W Abraham ter Harmsel, W Marchien van Baal, Peppino G C M Graziosi, Wim G V Quint, Johan W M Spruijt, Dorenda K E van Dijken, Daniëlle A M Heideman, Chris J L M Meijer

Br J Cancer. 2016 Aug 23; 115(5): 579–587. Published online 2016 Jul 14. doi: 10.1038/bjc.2016.200

PMCID:: PMC4997542

Abstract Article PDF–433K

Select item 485121714.

Validation of the FAM19A4/mir124-2 DNA methylation test for both lavage- and brush-based self-samples to detect cervical (pre)cancer in HPV-positive women

Lise M.A. De Strooper, Viola M.J. Verhoef, Johannes Berkhof, Albertus T. Hesselink, Helena M.E. de Bruin, Folkert J. van Kemenade, Remko P. Bosgraaf, Ruud L.M. Bekkers, Leon F.A.G. Massuger, Willem J.G. Melchers, Renske D.M. Steenbergen, Peter J.F. Snijders, Chris J.L.M. Meijer, Daniëlle A.M. Heideman

Gynecol Oncol. 2016 May; 141(2): 341–347. doi: 10.1016/j.ygyno.2016.02.012

PMCID:: PMC4851217

Abstract Article

Select item 457964615.

FAM19A4 is a novel cytokine ligand of formyl peptide receptor 1 (FPR1) and is able to promote the migration and phagocytosis of macrophages

Wenyan Wang, Ting Li, Xiaolin Wang, Wanxiong Yuan, Yingying Cheng, Heyu Zhang, Enquan Xu, Yingmei Zhang, Shuang Shi, Dalong Ma, Wenling Han

Cell Mol Immunol. 2015 Sep; 12(5): 615–624. Published online 2014 Aug 11. doi: 10.1038/cmi.2014.61

PMCID:: PMC4579646

Abstract Article PDF–1.9M

Select item 426658816.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Abstract Article PDF–3.1M

Select item 319082617.

Interactions of Pathological Hallmark Proteins: TUBULIN POLYMERIZATION PROMOTING PROTEIN/p25, β-AMYLOID, AND α-SYNUCLEIN

Judit Oláh, Orsolya Vincze, Dezső Virók, Dóra Simon, Zsolt Bozsó, Natália Tőkési, István Horváth, Emma Hlavanda, János Kovács, Anna Magyar, Mária Szűcs, Ferenc Orosz, Botond Penke, Judit Ovádi

J Biol Chem. 2011 Sep 30; 286(39): 34088–34100. Published online 2011 Aug 8. doi: 10.1074/jbc.M111.243907

PMCID:: PMC3190826

Abstract Article PDF–5.7M

Select item 317805918.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 289646419.

Personalized Smoking Cessation: Interactions between Nicotine Dose, Dependence and Quit-Success Genotype Score

Jed E Rose, Frédérique M Behm, Tomas Drgon, Catherine Johnson, George R Uhl

Mol Med. 2010 Jul-Aug; 16(7-8): 247–253. Published online 2010 Mar 17. doi: 10.2119/molmed.2009.00159

Correction in:: Mol Med. 2012; 18(1): 729.

PMCID:: PMC2896464

Abstract Article PDF–2.4M

Select item 135612920.

Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes

Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano

Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406

PMCID:: PMC1356129

Abstract Article PDF–438K

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