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Select item 112363241.

MATN4 as a target gene of HIF-1α promotes the proliferation and metastasis of osteosarcoma

Lu Zhang, Yujie Pan, Feng Pan, Songsong Huang, Fengyan Wang, Zhirui Zeng, Houping Chen, Xiaobin Tian

Aging (Albany NY) 2024 Jun 30; 16(12): 10462–10476. Published online 2024 Jun 17. doi: 10.18632/aging.205941

PMCID:: PMC11236324

Abstract Article PDF–1.9M

Select item 112183502.

A critical influence of HIF-1 on MMP-9 and Galectin-3 in oral lichen planus

Hala H. Hazzaa, Marwa A. M. El Shiekh, Osama Elkashty, Eman Magdy, Dalia Riad, Eman khalifa, Gasser M. Elewa, Naglaa M. Kamal

BMC Oral Health. 2024; 24: 756. Published online 2024 Jun 29. doi: 10.1186/s12903-024-04457-6

PMCID:: PMC11218350

Abstract Article PDF–1.6M

Select item 112039663.

Understanding Hypoxia-Driven Tumorigenesis: The Interplay of HIF1A, DNA Methylation, and Prolyl Hydroxylases in Head and Neck Squamous Cell Carcinoma

Julia Ostapowicz, Kamila Ostrowska, Agnieszka A. Rawłuszko-Wieczorek, Bartosz Wojtera, Sabina Koczot, Wojciech Golusiński, Wiktoria M. Suchorska

Int J Mol Sci. 2024 Jun; 25(12): 6495. Published online 2024 Jun 12. doi: 10.3390/ijms25126495

PMCID:: PMC11203966

Abstract Article PDF–10M

Select item 111848444.

Iron deficiency affects oxygen transport and activates HIF1 signaling pathway to regulate phenotypic transformation of VSMC in aortic dissection

Yuanyang Chen, Xu Li, Zhiwei Wang, Shun Yuan, Xiaoyan Shen, Xiaoping Xie, Kai Xing, Qingyi Zhu

Mol Med. 2024; 30: 90. Published online 2024 Jun 17. doi: 10.1186/s10020-024-00859-y

PMCID:: PMC11184844

Abstract Article PDF–6.9M

Select item 111642455.

Alternative splicing of CEACAM1 by Hypoxia-Inducible Factor–1α enhances tolerance to hepatic ischemia in mice and humans

Kenneth J. Dery, Hidenobu Kojima, Shoichi Kageyama, Kentaro Kadono, Hirofumi Hirao, Brian Cheng, Yuan Zhai, Douglas G. Farmer, Fady M. Kaldas, Xiaoyi Yuan, Holger K. Eltzschiasg, Jerzy W. Kupiec-Weglinski

Sci Transl Med. Author manuscript; available in PMC 2024 Jun 10.

Published in final edited form as: Sci Transl Med. 2023 Aug 2; 15(707): eadf2059. Published online 2023 Aug 2. doi: 10.1126/scitranslmed.adf2059

PMCID:: PMC11164245

Abstract Article PDF–2.9M

Select item 111598736.

Induction of hepatocyte growth factor activator gene expression under hypoxia activates the hepatocyte growth factor/c‐Met system via hypoxia inducible factor‐1 in pancreatic cancer

Yoshihiko Kitajima, Takao Ide, Takao Ohtsuka, Kohji Miyazaki

Cancer Sci. 2008 Jul; 99(7): 1341–1347. Published online 2008 Apr 16. doi: 10.1111/j.1349-7006.2008.00828.x

PMCID:: PMC11159873

Abstract Article PDF–265K

Select item 111596677.

Antisense hypoxia‐inducible factor 1α gene therapy enhances the therapeutic efficacy of doxorubicin to combat hepatocellular carcinoma

Fengjun Liu, Peijun Wang, Xian Jiang, Gang Tan, Haiquan Qiao, Hongchi Jiang, Geoffrey W. Krissansen, Xueying Sun

Cancer Sci. 2008 Oct; 99(10): 2055–2061. Published online 2008 Oct 14. doi: 10.1111/j.1349-7006.2008.00905.x

PMCID:: PMC11159667

Abstract Article PDF–417K

Select item 111596488.

Clinicopathological significance of nuclear factor‐kappa B, HIF‐1 alpha, and vascular endothelial growth factor expression in stage III colorectal cancer

Hyuk‐Chan Kwon, Sung Hyun Kim, Sung Yong Oh, Suee Lee, Kyung A Kwon, Jong Hoon Lee, Hong‐Jo Choi, Ki‐Jae Park, Hyung‐Sik Lee, Mee Sook Roh, Hyo‐Jin Kim

Cancer Sci. 2010 Jun; 101(6): 1557–1561. Published online 2010 Mar 4. doi: 10.1111/j.1349-7006.2010.01553.x

PMCID:: PMC11159648

Abstract Article PDF–290K

Select item 111361239.

The interaction of superoxide with nitric oxide destabilizes hypoxia-inducible factor-1α

B. Herr, J. Zhou, S. Dröse, B. Brüne

Cell Mol Life Sci. 2007 Dec; 64(24): 3295–3305. Published online 2007 Nov 9. doi: 10.1007/s00018-007-7371-9

PMCID:: PMC11136123

Abstract Article PDF–979K

Select item 1113146710.

Activation of hypoxia-inducible factor-1 regulates human histidine decarboxylase expression

H. J. Jeong, P. D. Moon, S. J. Kim, J. U. Seo, T. H. Kang, J. J. Kim, I. C. Kang, J. Y. Um, H. M. Kim, S. H. Hong

Cell Mol Life Sci. 2009 Apr; 66(7): 1309–1319. Published online 2009 Mar 7. doi: 10.1007/s00018-009-9001-1

PMCID:: PMC11131467

Abstract Article PDF–1.4M

Select item 1111585211.

15-Deoxy-Δ^12,14-prostaglandin-J₂ reveals a new pVHL-independent, lysosomal-dependent mechanism of HIF-1α degradation

Gemma Olmos, María I. Arenas, Raquel Bienes, María Jose Calzada, Julián Aragonés, Maria Laura Garcia-Bermejo, Manuel O. Landazuri, Javier Lucio-Cazaña

Cell Mol Life Sci. 2009 Jul; 66(13): 2167–2180. Published online 2009 May 21. doi: 10.1007/s00018-009-0039-x

PMCID:: PMC11115852

Abstract Article PDF–657K

Select item 1111562312.

Contribution of hypoxia to Alzheimer’s disease: is HIF-1α a mediator of neurodegeneration?

O. O. Ogunshola, X. Antoniou

Cell Mol Life Sci. 2009 Nov; 66(22): 3555–3563. Published online 2009 Sep 11. doi: 10.1007/s00018-009-0141-0

PMCID:: PMC11115623

Abstract Article PDF–212K

Select item 1111314413.

The HIF-1 transcription complex is essential for translational control of myeloid hematopoietic cell function by maintaining mTOR phosphorylation

Inna M. Yasinska, Bernhard F. Gibbs, Gurprit S. Lall, Vadim V. Sumbayev

Cell Mol Life Sci. 2014 Feb; 71(4): 699–710. Published online 2013 Jul 20. doi: 10.1007/s00018-013-1421-2

PMCID:: PMC11113144

Abstract Article PDF–886K

Select item 1110350214.

Activation of the hypoxia-inducible factor pathway protects against acute ischemic stroke by reprogramming central carbon metabolism

Sarah Madai, Pinar Kilic, Rolf M. Schmidt, Carlos Bas-Orth, Thomas Korff, Michael Büttner, Glynis Klinke, Gernot Poschet, Hugo H. Marti, Reiner Kunze

Theranostics. 2024; 14(7): 2856–2880. Published online 2024 Apr 29. doi: 10.7150/thno.88223

PMCID:: PMC11103502

Abstract Article PDF–3.5M

Select item 1109504615.

NER-factor DDB2 regulates HIF1α and hypoxia-response genes in HNSCC

Prashant V. Bommi, Vaibhav Chand, Nishit K. Mukhopadhyay, Pradip Raychaudhuri, Srilata Bagchi

Oncogene. Author manuscript; available in PMC 2024 May 15.

Published in final edited form as: Oncogene. 2020 Feb; 39(8): 1784–1796. Published online 2019 Nov 18. doi: 10.1038/s41388-019-1105-y

PMCID:: PMC11095046

Abstract Article PDF–1.8M

Select item 1108878416.

Thymic gene expression analysis reveals a potential link between HIF-1A and Th17/Treg imbalance in thymoma associated myasthenia gravis

İlayda Altınönder, Mustafa Kaya, Sibel P. Yentür, Arman Çakar, Hacer Durmuş, Gülçin Yegen, Berker Özkan, Yeşim Parman, Amr H. Sawalha, Guher Saruhan-Direskeneli

J Neuroinflammation. 2024; 21: 126. Published online 2024 May 11. doi: 10.1186/s12974-024-03095-7