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Items: 1 to 20 of 45

1.
Proximity Labeling Reveals Spatial Regulation of the Anaphase-Promoting Complex/Cyclosome by a Microtubule Adaptor
Xiaofu Cao, Adnan Shami Shah, Ethan J. Sanford, Marcus B. Smolka, Jeremy M. Baskin
ACS Chem Biol. Author manuscript; available in PMC 2023 Sep 16.
Published in final edited form as: ACS Chem Biol. 2022 Sep 16; 17(9): 2605–2618. Published online 2022 Aug 11. doi: 10.1021/acschembio.2c00527
PMCID:
PMC9933862
AbstractArticlePDF–2.5M
2.
Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration
Tara E. Tracy, Jesus Madero-Pérez, Danielle L. Swaney, Timothy S. Chang, Michelle Moritz, Csaba Konrad, Michael E. Ward, Erica Stevenson, Ruth Hüttenhain, Grant Kauwe, Maria Mercedes, Lauren Sweetland-Martin, Xu Chen, Sue-Ann Mok, Man Ying Wong, Maria Telpoukhovskaia, Sang-Won Min, Chao Wang, Peter Dongmin Sohn, Jordie Martin, Yungui Zhou, Wenjie Luo, John Q. Trojanowski, Virginia M.Y. Lee, Shiaoching Gong, Giovanni Manfredi, Giovanni Coppola, Nevan J. Krogan, Daniel H. Geschwind, Li Gan
Cell. Author manuscript; available in PMC 2022 Feb 19.
Published in final edited form as: Cell. 2022 Feb 17; 185(4): 712–728.e14. Published online 2022 Jan 20. doi: 10.1016/j.cell.2021.12.041
PMCID:
PMC8857049
AbstractArticlePDF–3.6M
3.
Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry
Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang
Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118
PMCID:
PMC8364181
AbstractArticlePDF–3.0M
4.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
5.
The X-linked intellectual disability gene product and E3 ubiquitin ligase KLHL15 degrades doublecortin proteins to constrain neuronal dendritogenesis
Jianing Song, Ronald A. Merrill, Andrew Y. Usachev, Stefan Strack
J Biol Chem. 2021 Jan-Jun; 296: 100082. Published online 2020 Nov 21. doi: 10.1074/jbc.RA120.016210
PMCID:
PMC7948412
AbstractArticlePDF–3.8M
6.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger
Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001
PMCID:
PMC7427327
AbstractArticle
7.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
8.
Doublecortin undergo nucleocytoplasmic transport via the RanGTPase signaling to promote glioma progression
Abiola Abdulrahman Ayanlaja, Guanquan Ji, Jie Wang, Yue Gao, Bo Cheng, Kouminin Kanwore, Lin Zhang, Ye Xiong, Piniel Alphayo Kambey, Dianshuai Gao
Cell Commun Signal. 2020; 18: 24. Published online 2020 Feb 12. doi: 10.1186/s12964-019-0485-5
PMCID:
PMC7017634
AbstractArticlePDF–6.3M
9.
A New Activity of Doublecortin in Recognition of the Phospho-FIGQY Tyrosine in the Cytoplasmic Domain of Neurofascin
Krishnakumar Kizhatil, Yi-Xin Wu, Anindita Sen, Vann Bennett
J Neurosci. 2002 Sep 15; 22(18): 7948–7958. doi: 10.1523/JNEUROSCI.22-18-07948.2002
PMCID:
PMC6758080
AbstractArticlePDF–2.1M
10.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations
Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu
Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3
PMCID:
PMC6742646
AbstractArticlePDF–1.2M
11.
A dominant dendrite phenotype caused by the disease-associated G253D mutation in doublecortin (DCX) is not due to its endocytosis defect
Chan Choo Yap, Laura Digilio, Kamil Kruczek, Matylda Roszkowska, Xiao-qin Fu, Judy S. Liu, Bettina Winckler
J Biol Chem. 2018 Dec 7; 293(49): 18890–18902. Published online 2018 Oct 5. doi: 10.1074/jbc.RA118.004462
PMCID:
PMC6295730
AbstractArticlePDF–3.7M
12.
rec-YnH enables simultaneous many-by-many detection of direct protein–protein and protein–RNA interactions
Jae-Seong Yang, Mireia Garriga-Canut, Nele Link, Carlo Carolis, Katrina Broadbent, Violeta Beltran-Sastre, Luis Serrano, Sebastian P. Maurer
Nat Commun. 2018; 9: 3747. Published online 2018 Sep 14. doi: 10.1038/s41467-018-06128-x
PMCID:
PMC6138660
AbstractArticlePDF–1.9M
13.
Evidence for reduced neurogenesis in the aging human hippocampus despite stable stem cell markers
Kathryn J. Mathews, Katherine M. Allen, Danny Boerrigter, Helen Ball, Cynthia Shannon Weickert, Kay L. Double
Aging Cell. 2017 Oct; 16(5): 1195–1199. Published online 2017 Aug 1. doi: 10.1111/acel.12641
PMCID:
PMC5595679
AbstractArticlePDF–662K
14.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
15.
Dynamic microtubule association of Doublecortin X (DCX) is regulated by its C-terminus
Maryam Moslehi, Dominic C. H. Ng, Marie A. Bogoyevitch
Sci Rep. 2017; 7: 5245. Published online 2017 Jul 12. doi: 10.1038/s41598-017-05340-x
PMCID:
PMC5507856
AbstractArticlePDF–7.3M
16.
Doublecortin is excluded from growing microtubule ends and recognizes the GDP-microtubule lattice
Andreas Ettinger, Jeffrey van Haren, Susana A. Ribeiro, Torsten Wittmann
Curr Biol. Author manuscript; available in PMC 2017 Jun 20.
Published in final edited form as: Curr Biol. 2016 Jun 20; 26(12): 1549–1555. Published online 2016 May 26. doi: 10.1016/j.cub.2016.04.020
PMCID:
PMC5023073
AbstractArticlePDF–2.9M
17.
Crystal Structures of the Human Doublecortin C- and N-terminal Domains in Complex with Specific Antibodies
Dominique Burger, Martine Stihle, Ashwani Sharma, Paola Di Lello, Jörg Benz, Brigitte D'Arcy, Maja Debulpaep, David Fry, Walter Huber, Thomas Kremer, Toon Laeremans, Hugues Matile, Alfred Ross, Arne C. Rufer, Guillaume Schoch, Michel O. Steinmetz, Jan Steyaert, Markus G. Rudolph, Ralf Thoma, Armin Ruf
J Biol Chem. 2016 Jul 29; 291(31): 16292–16306. Published online 2016 May 10. doi: 10.1074/jbc.M116.726547
PMCID:
PMC4965577
AbstractArticlePDF–3.8M
18.
hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes
Philippe Lamesch, Ning Li, Stuart Milstein, Changyu Fan, Tong Hao, Gabor Szabo, Zhenjun Hu, Kavitha Venkatesan, Graeme Bethel, Paul Martin, Jane Rogers, Stephanie Lawlor, Stuart McLaren, Amélie Dricot, Heather Borick, Michael E. Cusick, Jean Vandenhaute, Ian Dunham, David E. Hill, Marc Vidal
Genomics. 2007 Mar; 89(3): 307–315. doi: 10.1016/j.ygeno.2006.11.012
PMCID:
PMC4647941
AbstractArticle
19.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
20.
Mechanisms of HIV-1 Tat Neurotoxicity via CDK5 Translocation and Hyper-Activation: Role in HIV-Associated Neurocognitive Disorders
Jerel Adam Fields, Wilmar Dumaop, Leslie Crews, Anthony Adame, Brian Spencer, Jeff Metcalf, Johnny He, Edward Rockenstein, Eliezer Masliah
Curr HIV Res. Author manuscript; available in PMC 2016 Jan 1.
Published in final edited form as: Curr HIV Res. 2015; 13(1): 43–54. doi: 10.2174/1570162x13666150311164201
PMCID:
PMC4455959
AbstractArticlePDF–1.3M

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