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Select item 110688001.

Primordial germ cell DNA demethylation and development require DNA translesion synthesis

Pranay Shah, Ross Hill, Camille Dion, Stephen J. Clark, Abdulkadir Abakir, Jeroen Willems, Mark J. Arends, Juan I. Garaycoechea, Harry G. Leitch, Wolf Reik, Gerry P. Crossan

Nat Commun. 2024; 15: 3734. Published online 2024 May 3. doi: 10.1038/s41467-024-47219-2

PMCID:: PMC11068800

Abstract Article PDF–5.6M

Select item 109524832.

Dysregulation of Grainyhead‐like 3 expression causes widespread developmental defects

Zihao Deng, Tariq Butt, Benedicta D. Arhatari, Charbel Darido, Alana Auden, Dijina Swaroop, Darren D. Partridge, Katharina Haigh, Thao Nguyen, Jody J. Haigh, Marina R. Carpinelli, Stephen M. Jane

Dev Dyn. 2023 May; 252(5): 647–667. Published online 2023 Jan 19. doi: 10.1002/dvdy.565

PMCID:: PMC10952483

Abstract Article PDF–23M

Select item 109152753.

A selective defect in the glial wedge as part of the neuroepithelium disruption in hydrocephalus development in the mouse hyh model is associated with complete corpus callosum dysgenesis

Luis-Manuel Rodríguez-Pérez, Javier López-de-San-Sebastián, Isabel de Diego, Aníbal Smith, Ruth Roales-Buján, Antonio J. Jiménez, Patricia Paez-Gonzalez

Front Cell Neurosci. 2024; 18: 1330412. Published online 2024 Feb 21. doi: 10.3389/fncel.2024.1330412

PMCID:: PMC10915275

Abstract Article PDF–14M

Select item 107877914.

Loss of Mptx2 alters bacteria composition and intestinal homeostasis potentially by impairing autophagy

Weihui Yan, Shanshan Chen, Ying Wang, Yaying You, Ying Lu, Weipeng Wang, Bo Wu, Jun Du, Shicheng Peng, Wei Cai, Yongtao Xiao

Commun Biol. 2024; 7: 94. Published online 2024 Jan 13. doi: 10.1038/s42003-024-05785-7

PMCID:: PMC10787791

Abstract Article PDF–21M

Select item 106541015.

Transgenerational epigenetic effects imposed by neonicotinoid thiacloprid exposure

Ouzna Dali, Shereen D’Cruz, Louis Legoff, Mariam Diba Lahmidi, Celine Heitz, Pierre-Etienne Merret, Pierre-Yves Kernanec, Farzad Pakdel, Fatima Smagulova

Life Sci Alliance. 2024 Feb; 7(2): e202302237. Published online 2023 Nov 16. doi: 10.26508/lsa.202302237

PMCID:: PMC10654101

Abstract Article PDF–3.1M

Select item 106453996.

Insulin-Like Growth Factor-I Is Essential for Embryonic Bone Development

Yongmei Wang, Shigeki Nishida, Takeshi Sakata, Hashem Z. Elalieh, Wenhan Chang, Bernard P. Halloran, Steven B. Doty, Daniel D. Bikle

Endocrinology. Author manuscript; available in PMC 2023 Nov 14.

Published in final edited form as: Endocrinology. 2006 Oct; 147(10): 4753–4761. Published online 2006 Jul 20. doi: 10.1210/en.2006-0196

PMCID:: PMC10645399

Abstract Article PDF–2.8M

Select item 106004717.

Transcription and chromatin regulation by TAF4b during cellular quiescence of developing prospermatogonia

Megan A. Gura, Myles A. Bartholomew, Kimberly M. Abt, Soňa Relovská, Kimberly A. Seymour, Richard N. Freiman

Front Cell Dev Biol. 2023; 11: 1270408. Published online 2023 Oct 12. doi: 10.3389/fcell.2023.1270408

PMCID:: PMC10600471

Abstract Article PDF–4.4M

Select item 104928288.

Cell diversity and plasticity during atrioventricular heart valve EMTs

Jeremy Lotto, Rebecca Cullum, Sibyl Drissler, Martin Arostegui, Victoria C. Garside, Bettina M. Fuglerud, Makenna Clement-Ranney, Avinash Thakur, T. Michael Underhill, Pamela A. Hoodless

Nat Commun. 2023; 14: 5567. Published online 2023 Sep 9. doi: 10.1038/s41467-023-41279-6

PMCID:: PMC10492828

Abstract Article PDF–4.2M

Select item 104261549.

FAAP100 is required for the resolution of transcription-replication conflicts in primordial germ cells

Weiwei Xu, Yajuan Yang, Yongze Yu, Canxin Wen, Simin Zhao, Lili Cao, Shidou Zhao, Yingying Qin, Zi-Jiang Chen

BMC Biol. 2023; 21: 174. Published online 2023 Aug 15. doi: 10.1186/s12915-023-01676-1

PMCID:: PMC10426154

Abstract Article PDF–6.6M

Select item 1041654010.

Fance deficiency inhibits primordial germ cell proliferation associated with transcription–replication conflicts accumulate and DNA repair defects

Zhixian Zhou, Huan Yin, Suye Suye, Zhen Ren, Lei Yan, Liye Shi, Chun Fu

J Ovarian Res. 2023; 16: 160. Published online 2023 Aug 10. doi: 10.1186/s13048-023-01252-9

PMCID:: PMC10416540

Abstract Article PDF–15M

Select item 1040355211.

PRC1 suppresses a female gene regulatory network to ensure testicular differentiation

So Maezawa, Masashi Yukawa, Kazuteru Hasegawa, Ryo Sugiyama, Mizuho Iizuka, Mengwen Hu, Akihiko Sakashita, Miguel Vidal, Haruhiko Koseki, Artem Barski, Tony DeFalco, Satoshi H. Namekawa

Cell Death Dis. 2023 Aug; 14(8): 501. Published online 2023 Aug 4. doi: 10.1038/s41419-023-05996-6

PMCID:: PMC10403552

Abstract Article PDF–3.8M

Select item 1007976112.

SCAP contributes to embryonic angiogenesis by negatively regulating KISS-1 expression in mice

Guo Zheng, Yu Su, Li Wei, Yingcheng Yao, Yizhe Wang, Xiaoting Luo, Xing Wang, Xiong Z. Ruan, Danyang Li, Yaxi Chen

Cell Death Dis. 2023 Apr; 14(4): 249. Published online 2023 Apr 6. doi: 10.1038/s41419-023-05754-8

PMCID:: PMC10079761

Abstract Article PDF–9.1M

Select item 1002054613.

Unchanged PCNA and DNMT1 dynamics during replication in DNA ligase I-deficient cells but abnormal chromatin levels of non-replicative histone H1

Seema Khattri Bhandari, Nathaniel Wiest, Annahita Sallmyr, Ruofei Du, Laure Ferry, Pierre-Antoine Defossez, Alan E. Tomkinson

Sci Rep. 2023; 13: 4363. Published online 2023 Mar 16. doi: 10.1038/s41598-023-31367-4

PMCID:: PMC10020546

Abstract Article PDF–3.7M

Select item 997132014.

DNA repair protein FANCD2 has both ubiquitination-dependent and ubiquitination-independent functions during germ cell development

Simin Zhao, Chengzi Huang, Yajuan Yang, Weiwei Xu, Yongze Yu, Canxin Wen, Lili Cao, Fei Gao, Yingying Qin, Zi-Jiang Chen, Ting Guo, Shidou Zhao

J Biol Chem. 2023 Mar; 299(3): 102905. Published online 2023 Jan 13. doi: 10.1016/j.jbc.2023.102905

PMCID:: PMC9971320

Abstract Article PDF–4.2M

Select item 988872515.

Hepatic ribosomal protein S6 (Rps6) insufficiency results in failed bile duct development and loss of hepatocyte viability; a ribosomopathy-like phenotype that is partially p53-dependent

Sarah A. Comerford, Elizabeth A. Hinnant, Yidong Chen, Robert E. Hammer

PLoS Genet. 2023 Jan; 19(1): e1010595. Published online 2023 Jan 19. doi: 10.1371/journal.pgen.1010595

PMCID:: PMC9888725

Abstract Article PDF–6.9M

Select item 988700316.

Epigenetic control of cellular crosstalk defines gastrointestinal organ fate and function

Ryan J. Smith, Minggao Liang, Adrian Kwan Ho Loe, Theodora Yung, Ji-Eun Kim, Matthew Hudson, Michael D. Wilson, Tae-Hee Kim

Nat Commun. 2023; 14: 497. Published online 2023 Jan 30. doi: 10.1038/s41467-023-36228-2

PMCID:: PMC9887003

Abstract Article PDF–5.1M

Select item 987747517.

Mechanisms driving vestibular lamina formation and opening in the mouse

Tengyang Qiu, Abigail S. Tucker

J Anat. 2023 Feb; 242(2): 224–234. Published online 2022 Oct 1. doi: 10.1111/joa.13771

PMCID:: PMC9877475

Abstract Article PDF–12M

Select item 983366718.

DNA dioxygenases Tet2/3 regulate gene promoter accessibility and chromatin topology in lineage-specific loci to control epithelial differentiation

Guo-Dong Chen, Iqra Fatima, Qin Xu, Elena Rozhkova, Michael Y. Fessing, Andrei N. Mardaryev, Andrey A. Sharov, Guo-Liang Xu, Vladimir A. Botchkarev

Sci Adv. 2023 Jan; 9(2): eabo7605. Published online 2023 Jan 11. doi: 10.1126/sciadv.abo7605

PMCID:: PMC9833667

Abstract Article PDF–3.1M

Select item 983203219.

Mechanism of cystogenesis by Cd79a-driven, conditional mTOR activation in developing mouse nephrons

Linh Tran Nguyen Truc, Satoshi Matsuda, Akiko Takenouchi, Quynh Tran Thuy Huong, Yui Kotani, Tatsuhiko Miyazaki, Hiroaki Kanda, Katsuhiko Yoshizawa, Hiroyasu Tsukaguchi

Sci Rep. 2023; 13: 508. Published online 2023 Jan 10. doi: 10.1038/s41598-023-27766-2

PMCID:: PMC9832032

Abstract Article PDF–17M

Select item 955395120.

Neonatal ketone body elevation regulates postnatal heart development by promoting cardiomyocyte mitochondrial maturation and metabolic reprogramming

Danyang Chong, Yayun Gu, Tongyu Zhang, Yu Xu, Dandan Bu, Zhong Chen, Na Xu, Liangkui Li, Xiyu Zhu, Haiquan Wang, Yangqing Li, Feng Zheng, Dongjin Wang, Peng Li, Li Xu, Zhibin Hu, Chaojun Li

Cell Discov. 2022; 8: 106. Published online 2022 Oct 11. doi: 10.1038/s41421-022-00447-6