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Items: 1 to 20 of 231

1.
Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability
Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson
Cell. Author manuscript; available in PMC 2024 Oct 26.
Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008
PMCID:
PMC11209935
ArticlePDF–3.0M
2.
Interaction of DISC1 with the PTB domain of Tensin2
Salman Goudarzi, Luke J. M. Smith, Steffen Schütz, Sassan Hafizi
Cell Mol Life Sci. 2013 May; 70(9): 1663–1672. Published online 2012 Dec 12. doi: 10.1007/s00018-012-1228-6
PMCID:
PMC11113815
ArticlePDF–797K
3.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
ArticlePDF–23M
4.
CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment
Daphne J. Smits, Jordy Dekker, Rachel Schot, Brahim Tabarki, Amal Alhashem, Jeroen A. A. Demmers, Dick H. W. Dekkers, Antonio Romito, Peter J. van der Spek, Tjakko J. van Ham, Aida M. Bertoli-Avella, Grazia M. S. Mancini
Hum Genet. 2023; 142(3): 379–397. Published online 2022 Dec 20. doi: 10.1007/s00439-022-02511-3
PMCID:
PMC9950183
ArticlePDF–2.4M
5.
Conformational alteration in glycan induces phospholipase Cβ1 activation and angiogenesis
Sheng-Hung Wang, Jing-Yan Cheng, Hsiu-Hui Tsai, Tzu-Chi Lo, Jung-Tung Hung, Chun-Cheng Lin, Chien-Wei Lee, Yi-Hsuan Ho, Huan-Hsien Kuo, Alice L. Yu, John Yu
J Biomed Sci. 2022; 29: 105. Published online 2022 Dec 15. doi: 10.1186/s12929-022-00889-w
PMCID:
PMC9753400
ArticlePDF–8.8M
6.
The variants in PTPRB, TRAF3IP3, and DISC1 genes were associated with Graves’ disease in the Chinese population
Wei Li, Haidong Jiang, Xu Chen, Kevin Yang, Xindan Deng, Zheng Tang, Zhihui Hu, Xiaodan Zhang, Shihan Lin, Yuanlin Zou, Hui Wu
Medicine (Baltimore) 2022 Nov 11; 101(45): e31501. Published online 2022 Nov 11. doi: 10.1097/MD.0000000000031501
PMCID:
PMC9666212
ArticlePDF–527K
7.
MBD5 and MBD6 stabilize the BAP1 complex and promote BAP1-dependent cancer
Natsumi Tsuboyama, Aileen Patricia Szczepanski, Zibo Zhao, Lu Wang
Genome Biol. 2022; 23: 206. Published online 2022 Sep 30. doi: 10.1186/s13059-022-02776-x
PMCID:
PMC9523997
ArticlePDF–6.9M
8.
Hematopoietic transcription factor GFI1 promotes anchorage independence by sustaining ERK activity in cancer cells
Hao Wang, Zhenzhen Lin, Zhe Nian, Wei Zhang, Wenxu Liu, Fei Yan, Zengtuan Xiao, Xia Wang, Zhenfa Zhang, Zhenyi Ma, Zhe Liu
J Clin Invest. 2022 Sep 1; 132(17): e149551. Published online 2022 Sep 1. doi: 10.1172/JCI149551
PMCID:
PMC9433100
ArticlePDF–3.7M
9.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
ArticlePDF–2.5M
10.
Regulation of sensorimotor gating via Disc1/Huntingtin-mediated Bdnf transport in the cortico-striatal circuit
Hanna Jaaro-Peled, Sunil Kumar, Dalton Hughes, Akiko Sumitomo, Sun-Hong Kim, Sandra Zoubovsky, Yuki Hirota-Tsuyada, Diana Zala, Julie Bruyere, Brittany M. Katz, Beverly Huang, Rafael Flores, III, Soumya Narayan, Zhipeng Hou, Aris N. Economides, Takatoshi Hikida, William C. Wetsel, Karl Deisseroth, Susumu Mori, Nicholas J. Brandon, Motomasa Tanaka, Koko Ishizuka, Miles D. Houslay, Frédéric Saudou, Kafui Dzirasa, Akira Sawa, Toshifumi Tomoda
Mol Psychiatry. Author manuscript; available in PMC 2022 Aug 14.
Published in final edited form as: Mol Psychiatry. 2022 Mar; 27(3): 1805–1815. Published online 2022 Feb 14. doi: 10.1038/s41380-021-01389-3
PMCID:
PMC9272458
ArticlePDF–1.8M
11.
GFI1 regulates chromatin state essential in human endothelial‐to‐haematopoietic transition
Baoqiang Kang, Tian Zhang, Ke Huang, Tianyu Wang, Yuhang Li, Yuchan Mai, Jinbing Li, Shiying Dang, Zhishuai Zhang, Wenhao Huang, Junwei Wang, Minghui Gao, Yi Wang, Guangjin Pan
Cell Prolif. 2022 May; 55(5): e13244. Published online 2022 May 3. doi: 10.1111/cpr.13244
PMCID:
PMC9136496
ArticlePDF–8.4M
12.
Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling
Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser
Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151
PMCID:
PMC9105235
ArticlePDF–5.8M
13.
Combining fMRI and DISC1 gene haplotypes to understand working memory-related brain activity in schizophrenia
Maria Guardiola-Ripoll, Alejandro Sotero-Moreno, Carmen Almodóvar-Payá, Noemí Hostalet, Amalia Guerrero-Pedraza, Núria Ramiro, Jordi Ortiz-Gil, Bárbara Arias, Mercè Madre, Joan Soler-Vidal, Raymond Salvador, Peter J. McKenna, Edith Pomarol-Clotet, Mar Fatjó-Vilas
Sci Rep. 2022; 12: 7351. Published online 2022 May 5. doi: 10.1038/s41598-022-10660-8
PMCID:
PMC9072540
ArticlePDF–1.5M
14.
The involvement of Parkin-dependent mitophagy in the anti-cancer activity of Ginsenoside
Xin Sun, Yeting Hong, Yuhan Shu, Caixia Wu, Guiqin Ye, Hanxiao Chen, Hongying Zhou, Ruilan Gao, Jianbin Zhang
J Ginseng Res. 2022 Mar; 46(2): 266–274. Published online 2021 Jul 8. doi: 10.1016/j.jgr.2021.06.009
PMCID:
PMC9058836
ArticlePDF–2.9M
15.
Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis
Fenglong Jiao, Clinton Yu, Andrew Wheat, Xiaorong Wang, Scott D. Rychnovsky, Lan Huang
Anal Chem. Author manuscript; available in PMC 2022 Apr 30.
Published in final edited form as: Anal Chem. 2022 Mar 15; 94(10): 4236–4242. Published online 2022 Mar 2. doi: 10.1021/acs.analchem.1c04485
PMCID:
PMC9056026
ArticlePDF–1.0M
16.
GFI1 cooperates with IKZF1/IKAROS to activate gene expression in T-cell acute lymphoblastic leukemia
Wenxiang Sun, Jingtao Guo, David McClellan, Alexandra Poeschla, Diana Bareyan, Mattie J. Casey, Bradley R. Cairns, Dean Tantin, Michael E. Engel
Mol Cancer Res. Author manuscript; available in PMC 2022 Oct 1.
Published in final edited form as: Mol Cancer Res. 2022 Apr 1; 20(4): 501–514. doi: 10.1158/1541-7786.MCR-21-0352
PMCID:
PMC8983472
ArticlePDF–2.5M
17.
The D2R-DISC1 protein complex and associated proteins are altered in schizophrenia and normalized with antipsychotic treatment
Jijun Wang, Ping Su, Jian Yang, Lihua Xu, Aihua Yuan, Chunbo Li, Tianhong Zhang, Fang Dong, Jingjing Zhou, James Samsom, Albert H.C. Wong, Fang Liu
J Psychiatry Neurosci. 2022 Mar-Apr; 47(2): E134–E147. Published online 2022 Mar 31. doi: 10.1503/jpn.210145
PMCID:
PMC8979657
ArticlePDF–2.9M
18.
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy
Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang
Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003
PMCID:
PMC8897022
ArticlePDF–3.0M
19.
A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing
Alexandra Bergfort, Marco Preußner, Benno Kuropka, İbrahim Avşar Ilik, Tarek Hilal, Gert Weber, Christian Freund, Tuğçe Aktaş, Florian Heyd, Markus C. Wahl
Nat Commun. 2022; 13: 1132. Published online 2022 Mar 3. doi: 10.1038/s41467-022-28754-2
PMCID:
PMC8894380
ArticlePDF–5.6M
20.
Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome
Caroline Benz, Muhammad Ali, Izabella Krystkowiak, Leandro Simonetti, Ahmed Sayadi, Filip Mihalic, Johanna Kliche, Eva Andersson, Per Jemth, Norman E Davey, Ylva Ivarsson
Mol Syst Biol. 2022 Jan; 18(1): e10584. Published online 2022 Jan 19. doi: 10.15252/msb.202110584
PMCID:
PMC8769072
ArticlePDF–2.9M

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