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Select item 112511671.

MCM8 interacts with DDX5 to promote R-loop resolution

Canxin Wen, Lili Cao, Shuhan Wang, Weiwei Xu, Yongze Yu, Simin Zhao, Fan Yang, Zi-Jiang Chen, Shidou Zhao, Yajuan Yang, Yingying Qin

EMBO J. 2024 Jul; 43(14): 3044–3071. Published online 2024 Jun 10. doi: 10.1038/s44318-024-00134-0

PMCID:: PMC11251167

Abstract Article PDF–8.7M

Select item 111870622.

Structure of human DPPA3 bound to the UHRF1 PHD finger reveals its functional and structural differences from mouse DPPA3

Nao Shiraishi, Tsuyoshi Konuma, Yoshie Chiba, Sayaka Hokazono, Nao Nakamura, Md Hadiul Islam, Makoto Nakanishi, Atsuya Nishiyama, Kyohei Arita

Commun Biol. 2024; 7: 746. Published online 2024 Jun 19. doi: 10.1038/s42003-024-06434-9

PMCID:: PMC11187062

Abstract Article PDF–3.2M

Select item 109961863.

DPPA3 facilitates genome-wide DNA demethylation in mouse primordial germ cells

Keisuke Toriyama, Wan Kin Au Yeung, Azusa Inoue, Kazuki Kurimoto, Yukihiro Yabuta, Mitinori Saitou, Toshinobu Nakamura, Toru Nakano, Hiroyuki Sasaki

BMC Genomics. 2024; 25: 344. Published online 2024 Apr 5. doi: 10.1186/s12864-024-10192-7

PMCID:: PMC10996186

Abstract Article PDF–4.0M

Select item 105206374.

NLRP14 Safeguards Calcium Homeostasis via Regulating the K27 Ubiquitination of Nclx in Oocyte‐to‐Embryo Transition

Tie‐Gang Meng, Jia‐Ni Guo, Liu Zhu, Yike Yin, Feng Wang, Zhi‐Ming Han, Lei Lei, Xue‐Shan Ma, Yue Xue, Wei Yue, Xiao‐Qing Nie, Zheng‐Hui Zhao, Hong‐Yong Zhang, Si‐Min Sun, Ying‐Chun Ouyang, Yi Hou, Heide Schatten, Zhenyu Ju, Xiang‐Hong Ou, Zhen‐Bo Wang, Catherine C. L. Wong, Zhonghan Li, Qing‐Yuan Sun

Adv Sci (Weinh) 2023 Sep; 10(27): 2301940. Published online 2023 Jul 26. doi: 10.1002/advs.202301940

PMCID:: PMC10520637

Abstract Article PDF–6.6M

Select item 104261545.

FAAP100 is required for the resolution of transcription-replication conflicts in primordial germ cells

Weiwei Xu, Yajuan Yang, Yongze Yu, Canxin Wen, Simin Zhao, Lili Cao, Shidou Zhao, Yingying Qin, Zi-Jiang Chen

BMC Biol. 2023; 21: 174. Published online 2023 Aug 15. doi: 10.1186/s12915-023-01676-1

PMCID:: PMC10426154

Abstract Article PDF–6.6M

Select item 103904926.

Three-dimensional molecular architecture of mouse organogenesis

Fangfang Qu, Wenjia Li, Jian Xu, Ruifang Zhang, Jincan Ke, Xiaodie Ren, Xiaogao Meng, Lexin Qin, Jingna Zhang, Fangru Lu, Xin Zhou, Xi Luo, Zhen Zhang, Minhan Wang, Guangming Wu, Duanqing Pei, Jiekai Chen, Guizhong Cui, Shengbao Suo, Guangdun Peng

Nat Commun. 2023; 14: 4599. Published online 2023 Jul 31. doi: 10.1038/s41467-023-40155-7

PMCID:: PMC10390492

Abstract Article PDF–13M

Select item 102502057.

GCNA is a histone binding protein required for spermatogonial stem cell maintenance

Jonathan Ribeiro, Gerry P Crossan

Nucleic Acids Res. 2023 Jun 9; 51(10): 4791–4813. Published online 2023 Mar 15. doi: 10.1093/nar/gkad168

PMCID:: PMC10250205

Abstract Article PDF–10M

Select item 99713208.

DNA repair protein FANCD2 has both ubiquitination-dependent and ubiquitination-independent functions during germ cell development

Simin Zhao, Chengzi Huang, Yajuan Yang, Weiwei Xu, Yongze Yu, Canxin Wen, Lili Cao, Fei Gao, Yingying Qin, Zi-Jiang Chen, Ting Guo, Shidou Zhao

J Biol Chem. 2023 Mar; 299(3): 102905. Published online 2023 Jan 13. doi: 10.1016/j.jbc.2023.102905

PMCID:: PMC9971320

Abstract Article PDF–4.2M

Select item 97570609.

Structural basis for the unique multifaceted interaction of DPPA3 with the UHRF1 PHD finger

Keiichi Hata, Naohiro Kobayashi, Keita Sugimura, Weihua Qin, Deis Haxholli, Yoshie Chiba, Sae Yoshimi, Gosuke Hayashi, Hiroki Onoda, Takahisa Ikegami, Christopher B Mulholland, Atsuya Nishiyama, Makoto Nakanishi, Heinrich Leonhardt, Tsuyoshi Konuma, Kyohei Arita

Nucleic Acids Res. 2022 Nov 28; 50(21): 12527–12542. Published online 2022 Nov 24. doi: 10.1093/nar/gkac1082

PMCID:: PMC9757060

Abstract Article PDF–16M

Select item 953477210.

Embryo model completes gastrulation to neurulation and organogenesis

Gianluca Amadei, Charlotte E. Handford, Chengxiang Qiu, Joachim De Jonghe, Hannah Greenfeld, Martin Tran, Beth K. Martin, Dong-Yuan Chen, Alejandro Aguilera-Castrejon, Jacob H. Hanna, Michael B. Elowitz, Florian Hollfelder, Jay Shendure, David M. Glover, Magdalena Zernicka-Goetz

Nature. 2022; 610(7930): 143–153. Published online 2022 Aug 25. doi: 10.1038/s41586-022-05246-3

PMCID:: PMC9534772

Abstract Article PDF–29M

Select item 940767211.

Transcription–replication conflicts in primordial germ cells necessitate the Fanconi anemia pathway to safeguard genome stability

Yajuan Yang, Weiwei Xu, Fei Gao, Canxin Wen, Simin Zhao, Yongze Yu, Wenlin Jiao, Xin Mi, Yingying Qin, Zi-Jiang Chen, Shidou Zhao

Proc Natl Acad Sci U S A. 2022 Aug 23; 119(34): e2203208119. Published online 2022 Aug 15. doi: 10.1073/pnas.2203208119

PMCID:: PMC9407672

Abstract Article PDF–2.8M

Select item 920030712.

Deletion of Wt1 during early gonadogenesis leads to differences of sex development in male and female adult mice

Alejo Torres-Cano, Rosa Portella-Fortuny, Claudia Müller-Sánchez, Sonia Porras-Marfil, Marina Ramiro-Pareta, You-Ying Chau, Manuel Reina, Francesc X. Soriano, Ofelia M. Martínez-Estrada

PLoS Genet. 2022 Jun; 18(6): e1010240. Published online 2022 Jun 15. doi: 10.1371/journal.pgen.1010240

PMCID:: PMC9200307

Abstract Article PDF–4.3M

Select item 906611113.

Stella Regulates the Development of Female Germline Stem Cells by Modulating Chromatin Structure and DNA Methylation

Changliang Hou, Xinyan Zhao, Geng G. Tian, Ji Wu

Int J Biol Sci. 2022; 18(7): 3006–3018. Published online 2022 Apr 18. doi: 10.7150/ijbs.69240

PMCID:: PMC9066111

Abstract Article PDF–2.1M

Select item 894115414.

Single-cell transcriptomics identifies potential cells of origin of MYC rhabdoid tumors

Monika Graf, Marta Interlandi, Natalia Moreno, Dörthe Holdhof, Carolin Göbel, Viktoria Melcher, Julius Mertins, Thomas K. Albert, Dennis Kastrati, Amelie Alfert, Till Holsten, Flavia de Faria, Michael Meisterernst, Claudia Rossig, Monika Warmuth-Metz, Johannes Nowak, Gerd Meyer zu Hörste, Chloe Mayère, Serge Nef, Pascal Johann, Michael C. Frühwald, Martin Dugas, Ulrich Schüller, Kornelius Kerl

Nat Commun. 2022; 13: 1544. Published online 2022 Mar 22. doi: 10.1038/s41467-022-29152-4

PMCID:: PMC8941154

Abstract Article PDF–7.0M

Select item 828224115.

Single‐cell RNA‐Seq reveals a highly coordinated transcriptional program in mouse germ cells during primordial follicle formation

Yuanlin He, Qiuzhen Chen, Juncheng Dai, Yiqiang Cui, Chi Zhang, Xidong Wen, Jiazhao Li, Yue Xiao, Xiaoxu Peng, Mingxi Liu, Bin Shen, Jiahao Sha, Zhibin Hu, Jing Li, Wenjie Shu

Aging Cell. 2021 Jul; 20(7): e13424. Published online 2021 Jun 26. doi: 10.1111/acel.13424

PMCID:: PMC8282241

Abstract Article PDF–3.6M

Select item 790202716.

Maternal UHRF1 Is Essential for Transcription Landscapes and Repression of Repetitive Elements During the Maternal-to-Zygotic Transition

Yanqing Wu, Juan Dong, Shenglei Feng, Qiang Zhao, Peng Duan, Mengneng Xiong, Yujiao Wen, Chunyu Lv, Xiaoli Wang, Shuiqiao Yuan

Front Cell Dev Biol. 2020; 8: 610773. Published online 2021 Feb 9. doi: 10.3389/fcell.2020.610773

PMCID:: PMC7902027

Abstract Article PDF–3.9M

Select item 752668617.

Quantitative Optical Diffraction Tomography Imaging of Mouse Platelets

Tess A. Stanly, Rakesh Suman, Gulab Fatima Rani, Peter J. O’Toole, Paul M. Kaye, Ian S. Hitchcock

Front Physiol. 2020; 11: 568087. Published online 2020 Sep 16. doi: 10.3389/fphys.2020.568087

PMCID:: PMC7526686

Abstract Article PDF–1.9M

Select item 718175118.

Ptch2/Gas1 and Ptch1/Boc differentially regulate Hedgehog signalling in murine primordial germ cell migration

Yeonjoo Kim, Jiyoung Lee, Maisa Seppala, Martyn T. Cobourne, Soo-Hyun Kim

Nat Commun. 2020; 11: 1994. Published online 2020 Apr 24. doi: 10.1038/s41467-020-15897-3

Correction in:: Nat Commun. 2020; 11: 2275.

PMCID:: PMC7181751

Abstract Article PDF–5.9M

Select item 705336119.

Ozone-Induced Aryl Hydrocarbon Receptor Activation Controls Lung Inflammation via Interleukin-22 Modulation

Chloé Michaudel, Florent Bataille, Isabelle Maillet, Louis Fauconnier, Cyril Colas, Harry Sokol, Marjolène Straube, Aurélie Couturier-Maillard, Laure Dumoutier, Jacques van Snick, Valérie F. Quesniaux, Dieudonnée Togbe, Bernhard Ryffel

Front Immunol. 2020; 11: 144. Published online 2020 Feb 25. doi: 10.3389/fimmu.2020.00144

PMCID:: PMC7053361

Abstract Article PDF–2.3M

Select item 673449320.

Dppa3 is critical for Lin28a-regulated ES cells naïve–primed state conversion

Hui Sang, Dan Wang, Shuang Zhao, Jinxin Zhang, Yan Zhang, Jia Xu, Xiaoniao Chen, Yan Nie, Kaiyue Zhang, Shuaiqiang Zhang, Yuebing Wang, Na Wang, Fengxia Ma, Ling Shuai, Zongjin Li, Na Liu

J Mol Cell Biol. 2019 Jun; 11(6): 474–488. Published online 2018 Nov 27. doi: 10.1093/jmcb/mjy069

PMCID:: PMC6734493

Abstract Article PDF–1.5M

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