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Select item 90396791.

Overproduction of hydrogen sulfide, generated by cystathionine β-synthase, disrupts brain wave patterns and contributes to neurobehavioral dysfunction in a rat model of down syndrome

Theodora Panagaki, Laura Lozano-Montes, Lucia Janickova, Karim Zuhra, Marcell P. Szabo, Tomas Majtan, Gregor Rainer, Damien Maréchal, Yann Herault, Csaba Szabo

Redox Biol. 2022 May; 51: 102233. Published online 2022 Jan 13. doi: 10.1016/j.redox.2022.102233

PMCID:: PMC9039679

Abstract Article PDF–17M

Select item 80289692.

Upregulation of cystathione β‐synthase and p70S6K/S6 in neonatal hypoxic ischemic brain injury

Mirna Lechpammer, Yen P. Tran, Pia Wintermark, Veronica Martínez‐Cerdeño, Viswanathan V. Krishnan, Waseem Ahmed, Robert F. Berman, Frances E. Jensen, Evgeny Nudler, David Zagzag

Brain Pathol. 2017 Jul; 27(4): 449–458. Published online 2016 Aug 28. doi: 10.1111/bpa.12421

Correction in:: Brain Pathol. 2017 Nov; 27(6): 856.

PMCID:: PMC8028969

Abstract Article PDF–949K

Select item 69870943.

Hydrogen sulfide stimulates Mycobacterium tuberculosis respiration, growth and pathogenesis

Vikram Saini, Krishna C. Chinta, Vineel P. Reddy, Joel N. Glasgow, Asaf Stein, Dirk A. Lamprecht, Md. Aejazur Rahman, Jared S. Mackenzie, Barry E. Truebody, John H. Adamson, Tafara T. R. Kunota, Shannon M. Bailey, Douglas R. Moellering, Jack R. Lancaster, Jr., Adrie J. C. Steyn

Nat Commun. 2020; 11: 557. Published online 2020 Jan 28. doi: 10.1038/s41467-019-14132-y

PMCID:: PMC6987094

Abstract Article PDF–2.9M

Select item 67426464.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 59671595.

Prenatal maternal stress induces visceral hypersensitivity of adult rat offspring through activation of cystathionine-β-synthase signaling in primary sensory neurons

Hong-Jun Wang, Xue Xu, Rui-Hua Xie, Yun-Yun Rui, Ping-An Zhang, Xiao-Jue Zhu, Guang-Yin Xu

Mol Pain. 2018; 14: 1744806918777406. Published online 2018 Apr 30. doi: 10.1177/1744806918777406

PMCID:: PMC5967159

Abstract Article PDF–703K

Select item 51312766.

Inhibition of cystathionine β-synthetase suppresses sodium channel activities of dorsal root ganglion neurons of rats with lumbar disc herniation

Jun Yan, Shufen Hu, Kang Zou, Min Xu, Qianliang Wang, Xiuhua Miao, Shan Ping Yu, Guang-Yin Xu

Sci Rep. 2016; 6: 38188. Published online 2016 Dec 1. doi: 10.1038/srep38188

PMCID:: PMC5131276

Abstract Article PDF–1.2M

Select item 51177577.

Effect of endotoxemia in mice genetically deficient in cystathionine-γ-lyase, cystathionine-β-synthase or 3-mercaptopyruvate sulfurtransferase

Akbar Ahmad, Domokos Gerö, Gabor Olah, Csaba Szabo

Int J Mol Med. 2016 Dec; 38(6): 1683–1692. Published online 2016 Oct 14. doi: 10.3892/ijmm.2016.2771

PMCID:: PMC5117757

Abstract Article PDF–1.0M

Select item 50708858.

Polymorphisms of cystathionine beta-synthase gene are associated with susceptibility to sepsis

Christoph Sponholz, Marcel Kramer, Franziska Schöneweck, Uwe Menzel, Kolsoum Inanloo Rahatloo, Evangelos J Giamarellos-Bourboulis, Vassileios Papavassileiou, Korina Lymberopoulou, Maria Pavlaki, Ioannis Koutelidakis, Ioannis Perdios, André Scherag, Michael Bauer, Matthias Platzer, Klaus Huse

Eur J Hum Genet. 2016 Jul; 24(7): 1041–1048. Published online 2015 Oct 28. doi: 10.1038/ejhg.2015.231

PMCID:: PMC5070885

Abstract Article PDF–774K

Select item 49148769.

Possible selection of host folate pathway gene polymorphisms in patients with malaria from a malaria endemic region in North East India

Darshana Mirgal, Kanjaksha Ghosh, Jagadish Mahanta, Prafulla Dutta, Shrimati Shetty

Trans R Soc Trop Med Hyg. 2016 May; 110(5): 294–298. Published online 2016 May 18. doi: 10.1093/trstmh/trw026

PMCID:: PMC4914876

Abstract Article PDF–167K

Select item 459138210.

Prenatal alcohol exposure alters methyl metabolism and programs serotonin transporter and glucocorticoid receptor expression in brain

Ying Fai Ngai, Dian C. Sulistyoningrum, Ryan O'Neill, Sheila M. Innis, Joanne Weinberg, Angela M. Devlin

Am J Physiol Regul Integr Comp Physiol. 2015 Sep; 309(5): R613–R622. Published online 2015 Jul 15. doi: 10.1152/ajpregu.00075.2015

PMCID:: PMC4591382

Abstract Article

Select item 451584211.

TLR4 upregulates CBS expression through NF-κB activation in a rat model of irritable bowel syndrome with chronic visceral hypersensitivity

Bo Yuan, Wei-Hong Tang, Li-Juan Lu, Yuan Zhou, Hong-Yan Zhu, You-Lang Zhou, Hong-Hong Zhang, Chuang-Ying Hu, Guang-Yin Xu

World J Gastroenterol. 2015 Jul 28; 21(28): 8615–8628. Published online 2015 Jul 28. doi: 10.3748/wjg.v21.i28.8615

PMCID:: PMC4515842

Abstract Article PDF–2.2M

Select item 440084212.

Hyperhomocysteinemia inhibits post-injury reendothelialization in mice

Hongmei Tan, Xiaohua Jiang, Fan Yang, Zhaohui Li, Dan Liao, JoAnn Trial, Mark J. Magera, William Durante, Xiaofeng Yang, Hong Wang

Cardiovasc Res. Author manuscript; available in PMC 2015 Apr 17.

Published in final edited form as: Cardiovasc Res. 2006 Jan; 69(1): 253–262. Published online 2005 Oct 13. doi: 10.1016/j.cardiores.2005.08.016

PMCID:: PMC4400842

Abstract Article PDF–552K

Select item 439721213.

Cystathionine β-Synthase Inhibition Is a Potential Therapeutic Approach to Treatment of Ischemic Injury

Su Jing Chan, Chou Chai, Tze Wei Lim, Mie Yamamoto, Eng H Lo, Mitchell Kim Peng Lai, Peter Tsun Hon Wong

ASN Neuro. 2015 Mar-Apr; 7(2): 1759091415578711. Published online 2015 Mar 30. doi: 10.1177/1759091415578711

PMCID:: PMC4397212

Abstract Article PDF–1.5M

Select item 437448814.

Hypoxia-Inducible Factors Regulate Human and Rat Cystathionine β-Synthase Gene Expression

Naoharu Takano, Ying-Jie Peng, Ganesh K. Kumar, Weibo Luo, Hongxia Hu, Larissa A. Shimoda, Makoto Suematsu, Nanduri R. Prabhakar, Gregg L. Semenza

Biochem J. Author manuscript; available in PMC 2015 Mar 26.

Published in final edited form as: Biochem J. 2014 Mar 1; 458(2): 203–211. doi: 10.1042/BJ20131350

PMCID:: PMC4374488

Abstract Article PDF–787K

Select item 426658815.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Abstract Article PDF–3.1M

Select item 426337116.

A Massively Parallel Pipeline to Clone DNA Variants and Examine Molecular Phenotypes of Human Disease Mutations

Xiaomu Wei, Jishnu Das, Robert Fragoza, Jin Liang, Francisco M. Bastos de Oliveira, Hao Ran Lee, Xiujuan Wang, Matthew Mort, Peter D. Stenson, David N. Cooper, Steven M. Lipkin, Marcus B. Smolka, Haiyuan Yu

PLoS Genet. 2014 Dec; 10(12): e1004819. Published online 2014 Dec 11. doi: 10.1371/journal.pgen.1004819