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Items: 1 to 20 of 42

1.
GLS2 is a tumor suppressor and a regulator of ferroptosis in hepatocellular carcinoma
Sawako Suzuki, Divya Venkatesh, Hiroaki Kanda, Akitoshi Nakayama, Hiroyuki Hosokawa, Eunyoung Lee, Takashi Miki, Brent R. Stockwell, Koutaro Yokote, Tomoaki Tanaka, Carol Prives
Cancer Res. Author manuscript; available in PMC 2024 Apr 29.
Published in final edited form as: Cancer Res. 2022 Sep 16; 82(18): 3209–3222. doi: 10.1158/0008-5472.CAN-21-3914
PMCID:
PMC11057045
AbstractArticlePDF–2.6M
2.
Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context
Marcel Morgenstern, Christian D. Peikert, Philipp Lübbert, Ida Suppanz, Cinzia Klemm, Oliver Alka, Conny Steiert, Nataliia Naumenko, Alexander Schendzielorz, Laura Melchionda, Wignand W.D. Mühlhäuser, Bettina Knapp, Jakob D. Busch, Sebastian B. Stiller, Stefan Dannenmaier, Caroline Lindau, Mariya Licheva, Christopher Eickhorst, Riccardo Galbusera, Ralf M. Zerbes, Michael T. Ryan, Claudine Kraft, Vera Kozjak-Pavlovic, Friedel Drepper, Sven Dennerlein, Silke Oeljeklaus, Nikolaus Pfanner, Nils Wiedemann, Bettina Warscheid
Cell Metab. 2021 Dec 7; 33(12): 2464–2483.e18. doi: 10.1016/j.cmet.2021.11.001
PMCID:
PMC8664129
AbstractArticle
3.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
4.
Structure and activation mechanism of the human liver-type glutaminase GLS2
Igor M. Ferreira, José Edwin N. Quesñay, Alliny CS. Bastos, Camila T. Rodrigues, Melanie Vollmar, Tobias Krojer, Claire Strain-Damerell, Nicola A. Burgess-Brown, Frank von Delft, Wyatt W. Yue, Sandra MG. Dias, Andre LB. Ambrosio
Biochimie. 2021 Jun; 185: 96–104. doi: 10.1016/j.biochi.2021.03.009
PMCID:
PMC8130709
AbstractArticlePDF–1.8M
5.
Glutaminase isoforms expression switches microRNA levels and oxidative status in glioblastoma cells
Juan de los Santos-Jiménez, José A. Campos-Sandoval, Clara Márquez-Torres, Nieves Urbano-Polo, David Brøndegaard, Mercedes Martín-Rufián, Carolina Lobo, Ana Peñalver, María C. Gómez-García, Janet Martín-Campos, Carolina Cardona, Laura Castilla, Felipe da Costa Souza, Tzuling Cheng, Juan A. Segura, Francisco J. Alonso, Rui Curi, Alison Colquhoun, Ralph J. DeBerardinis, Javier Márquez, José M. Matés
J Biomed Sci. 2021; 28: 14. Published online 2021 Feb 20. doi: 10.1186/s12929-021-00712-y
PMCID:
PMC7897386
AbstractArticlePDF–3.1M
6.
Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex
Marissa M. Minor, F. Blaine Hollinger, Adrienne L. McNees, Sung Yun Jung, Antrix Jain, Joseph M. Hyser, Karl-Dimiter Bissig, Betty L. Slagle
Cells. 2020 Apr; 9(4): 834. Published online 2020 Mar 30. doi: 10.3390/cells9040834
PMCID:
PMC7226812
AbstractArticlePDF–2.3M
7.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
8.
Nuclear Translocation of Glutaminase GLS2 in Human Cancer Cells Associates with Proliferation Arrest and Differentiation
Amada R. López de la Oliva, José A. Campos-Sandoval, María C. Gómez-García, Carolina Cardona, Mercedes Martín-Rufián, Fernando J. Sialana, Laura Castilla, Narkhyun Bae, Carolina Lobo, Ana Peñalver, Marina García-Frutos, David Carro, Victoria Enrique, José C. Paz, Raghavendra G. Mirmira, Antonia Gutiérrez, Francisco J. Alonso, Juan A. Segura, José M. Matés, Gert Lubec, Javier Márquez
Sci Rep. 2020; 10: 2259. Published online 2020 Feb 10. doi: 10.1038/s41598-020-58264-4
Correction in:
Sci Rep. 2021; 11: 249.
PMCID:
PMC7010782
AbstractArticlePDF–4.4M
9.
Liver-Type Glutaminase GLS2 Is a Druggable Metabolic Node in Luminal-Subtype Breast Cancer
Michael J. Lukey, Ahmad A. Cluntun, William P. Katt, Miao-chong J. Lin, Joseph E. Druso, Sekar Ramachandran, Jon W. Erickson, Henry H. Le, Zhihan-Emily Wang, Bryant Blank, Kai Su Greene, Richard A. Cerione
Cell Rep. Author manuscript; available in PMC 2020 Jan 2.
Published in final edited form as: Cell Rep. 2019 Oct 1; 29(1): 76–88.e7. doi: 10.1016/j.celrep.2019.08.076
PMCID:
PMC6939472
AbstractArticlePDF–2.5M
10.
Human genetic variation in GLS2 is associated with development of complicated Staphylococcus aureus bacteremia
William K. Scott, Felix Mba Medie, Felicia Ruffin, Batu K. Sharma-Kuinkel, Derek D. Cyr, Shengru Guo, Derek M. Dykxhoorn, Robert L. Skov, Niels E. Bruun, Anders Dahl, Christian J. Lerche, Andreas Petersen, Anders Rhod Larsen, Trine Kiilerich Lauridsen, Helle Krogh Johansen, Henrik Ullum, Erik Sørensen, Christian Hassager, Henning Bundgaard, Henrik C. Schønheyder, Christian Torp-Pedersen, Louise Bruun Østergaard, Magnus Arpi, Flemming Rosenvinge, Lise T. Erikstrup, Mahtab Chehri, Peter Søgaard, Paal S. Andersen, Vance G. Fowler, Jr.
PLoS Genet. 2018 Oct; 14(10): e1007667. Published online 2018 Oct 5. doi: 10.1371/journal.pgen.1007667
PMCID:
PMC6192642
AbstractArticlePDF–936K
11.
High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy
Samuel A. Hasson, Lesley A. Kane, Koji Yamano, Chiu-Hui Huang, Danielle A. Sliter, Eugen Buehler, Chunxin Wang, Sabrina M. Heman-Ackah, Tara Hessa, Rajarshi Guha, Scott E. Martin, Richard J. Youle
Nature. Author manuscript; available in PMC 2018 Mar 7.
Published in final edited form as: Nature. 2013 Dec 12; 504(7479): 291–295. Published online 2013 Nov 24. doi: 10.1038/nature12748
PMCID:
PMC5841086
AbstractArticlePDF–5.3M
12.
The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats
Camila Cristina Pasquali, Zeyaul Islam, Douglas Adamoski, Igor Monteze Ferreira, Ricardo Diogo Righeto, Jefferson Bettini, Rodrigo Villares Portugal, Wyatt Wai-yin Yue, Ana Gonzalez, Sandra Martha Gomes Dias, Andre Luis Berteli Ambrosio
J Biol Chem. 2017 Jul 7; 292(27): 11572–11585. Published online 2017 May 19. doi: 10.1074/jbc.M117.787291
PMCID:
PMC5500818
AbstractArticlePDF–3.6M
13.
The p53-SET Interplays Reveal A New Mode of Acetylation-dependent Regulation
Donglai Wang, Ning Kon, Gorka Lasso, Le Jiang, Wenchuan Leng, Wei-Guo Zhu, Jun Qin, Barry Honig, Wei Gu
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Oct 6; 538(7623): 118–122. Published online 2016 Sep 14. doi: 10.1038/nature19759
PMCID:
PMC5333498
AbstractArticlePDF–4.5M
14.
CFIm25 regulates glutaminase alternative terminal exon definition to modulate miR-23 function
Chioniso P. Masamha, Zheng Xia, Natoya Peart, Scott Collum, Wei Li, Eric J. Wagner, Ann-Bin Shyu
RNA. 2016 Jun; 22(6): 830–838. doi: 10.1261/rna.055939.116
PMCID:
PMC4878610
AbstractArticlePDF–270K
15.
The combination of three molecular markers can be a valuable predictive tool for the prognosis of hepatocellular carcinoma patients
Sheng-Sen Chen, Kang-Kang Yu, Qing-Xia Ling, Chong Huang, Ning Li, Jian-Ming Zheng, Su-Xia Bao, Qi Cheng, Meng-Qi Zhu, Ming-Quan Chen
Sci Rep. 2016; 6: 24582. Published online 2016 Apr 15. doi: 10.1038/srep24582
PMCID:
PMC4832332
AbstractArticlePDF–738K
16.
Glutaminase 2 is a novel negative regulator of small GTPase Rac1 and mediates p53 function in suppressing metastasis
Cen Zhang, Juan Liu, Yuhan Zhao, Xuetian Yue, Yu Zhu, Xiaolong Wang, Hao Wu, Felix Blanco, Shaohua Li, Gyan Bhanot, Bruce G Haffty, Wenwei Hu, Zhaohui Feng
eLife. 2016; 5: e10727. Published online 2016 Jan 11. doi: 10.7554/eLife.10727
PMCID:
PMC4749555
AbstractArticlePDF–4.1M
17.
Myc promotes glutaminolysis in human neuroblastoma through direct activation of glutaminase 2
Daibiao Xiao, Ping Ren, Hexiu Su, Ming Yue, Ruijuan Xiu, Yufeng Hu, Hudan Liu, Guoliang Qing
Oncotarget. 2015 Dec 1; 6(38): 40655–40666. Published online 2015 Oct 19. doi: 10.18632/oncotarget.5821
PMCID:
PMC4747359
AbstractArticlePDF–8.1M
18.
Both GLS silencing and GLS2 overexpression synergize with oxidative stress against proliferation of glioma cells
Mercedes Martín-Rufián, Renata Nascimento-Gomes, Ana Higuero, Amanda R. Crisma, José A. Campos-Sandoval, María C. Gómez-García, Carolina Cardona, Tzuling Cheng, Carolina Lobo, Juan A. Segura, Francisco J. Alonso, Monika Szeliga, Jan Albrecht, Rui Curi, Javier Márquez, Alison Colquhoun, Ralph J. DeBerardinis, José M. Matés
J Mol Med (Berl) Author manuscript; available in PMC 2015 Feb 14.
Published in final edited form as: J Mol Med (Berl). 2014 Mar; 92(3): 277–290. Published online 2013 Nov 26. doi: 10.1007/s00109-013-1105-2
PMCID:
PMC4327995
AbstractArticlePDF–1.6M
19.
An atlas of genetic influences on human blood metabolites
So-Youn Shin, Eric B. Fauman, Ann-Kristin Petersen, Jan Krumsiek, Rita Santos, Jie Huang, Matthias Arnold, Idil Erte, Vincenzo Forgetta, Tsun-Po Yang, Klaudia Walter, Cristina Menni, Lu Chen, Louella Vasquez, Ana M. Valdes, Craig L. Hyde, Vicky Wang, Daniel Ziemek, Phoebe Roberts, Li Xi, Elin Grundberg, The Multiple Tissue Human Expression Resource (MuTHER) Consortium, Melanie Waldenberger, J. Brent Richards, Robert P. Mohney, Michael V. Milburn, Sally L. John, Jeff Trimmer, Fabian J. Theis, John P. Overington, Karsten Suhre, M. Julia Brosnan, Christian Gieger, Gabi Kastenmüller, Tim D Spector, Nicole Soranzo
Nat Genet. Author manuscript; available in PMC 2014 Dec 1.
Published in final edited form as: Nat Genet. 2014 Jun; 46(6): 543–550. Published online 2014 May 11. doi: 10.1038/ng.2982
PMCID:
PMC4064254
AbstractArticlePDF–2.4M
20.
Glutaminase 2 negatively regulates the PI3K/AKT signaling and shows tumor suppression activity in human hepatocellular carcinoma
Juan Liu, Cen Zhang, Meihua Lin, Wei Zhu, Yingjian Liang, Xuehui Hong, Yuhan Zhao, Ken H. Young, Wenwei Hu, Zhaohui Feng
Oncotarget. 2014 May; 5(9): 2635–2647. Published online 2014 Mar 26. doi: 10.18632/oncotarget.1862
PMCID:
PMC4058033
AbstractArticlePDF–4.4M

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