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Select item 116183631.

Gelsolin alleviates rheumatoid arthritis by negatively regulating NLRP3 inflammasome activation

Jiyeon Lee, Fumiyuki Sasaki, Eri Koike, Minjeong Cho, Yeongun Lee, So Hee Dho, Jina Lee, Eunji Lee, Eri Toyohara, Mika Sunakawa, Mariko Ishibashi, Huynh Hiep Hung, Saki Nishioka, Ritsuko Komine, Chiaki Okura, Masumi Shimizu, Masahito Ikawa, Akihiko Yoshimura, Rimpei Morita, Lark Kyun Kim

Cell Death Differ. 2024 Dec; 31(12): 1679–1694. Published online 2024 Aug 24. doi: 10.1038/s41418-024-01367-6

PMCID:: PMC11618363

Abstract Article PDF–6.3M

Select item 103078522.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 101758443.

A human FLII gene variant alters sarcomeric actin thin filament length and predisposes to cardiomyopathy

Yasuhide Kuwabara, Allen J. York, Suh-Chin Lin, Michelle A. Sargent, Kelly M. Grimes, James P. Pirruccello, Jeffery D. Molkentin

Proc Natl Acad Sci U S A. 2023 May 9; 120(19): e2213696120. Published online 2023 May 1. doi: 10.1073/pnas.2213696120

PMCID:: PMC10175844

Abstract Article PDF–1.3M

Select item 97906754.

PRDM16 expression and function in mammalian cochlear development

Michael Ebeid, Kathy Barnas, Hongji Zhang, Amal Yaghmour, Gabriele Noreikaite, Bryan C. Bjork

Dev Dyn. 2022 Oct; 251(10): 1666–1683. Published online 2022 May 7. doi: 10.1002/dvdy.480

PMCID:: PMC9790675

Abstract Article PDF–17M

Select item 96038605.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 94819336.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 87046987.

The Pathophysiologic Role of Gelsolin in Chronic Kidney Disease: Focus on Podocytes

Chia-Jung Yu, Dian W. Damaiyanti, Shian-Jang Yan, Chih-Hsing Wu, Ming-Jer Tang, Dar-Bin Shieh, Peter P. Liu, Ping-Yen Liu

Int J Mol Sci. 2021 Dec; 22(24): 13281. Published online 2021 Dec 10. doi: 10.3390/ijms222413281

PMCID:: PMC8704698

Abstract Article PDF–3.3M

Select item 83205298.

Secreted gelsolin inhibits DNGR-1-dependent cross-presentation and cancer immunity

Evangelos Giampazolias, Oliver Schulz, Kok Haw Jonathan Lim, Neil C. Rogers, Probir Chakravarty, Naren Srinivasan, Oliver Gordon, Ana Cardoso, Michael D. Buck, Enzo Z. Poirier, Johnathan Canton, Santiago Zelenay, Stefano Sammicheli, Natalia Moncaut, Sunita Varsani-Brown, Ian Rosewell, Caetano Reis e Sousa

Cell. 2021 Jul 22; 184(15): 4016–4031.e22. doi: 10.1016/j.cell.2021.05.021

PMCID:: PMC8320529

Abstract Article

Select item 79387709.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 780831510.

Villin-1 and Gelsolin Regulate Changes in Actin Dynamics That Affect Cell Survival Signaling Pathways and Intestinal Inflammation

Swati Roy, Amin Esmaeilniakooshkghazi, Srinivas Patnaik, Yaohong Wang, Sudeep P. George, Afzal Ahrorov, Jason K. Hou, Allan J. Herron, Hiromi Sesaki, Seema Khurana

Gastroenterology. Author manuscript; available in PMC 2021 Jan 14.

Published in final edited form as: Gastroenterology. 2018 Apr; 154(5): 1405–1420.e2. Published online 2017 Dec 21. doi: 10.1053/j.gastro.2017.12.016

PMCID:: PMC7808315

Abstract Article PDF–1.3M

Select item 741599111.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 670527112.

SRF Phosphorylation by Glycogen Synthase Kinase-3 Promotes Axon Growth in Hippocampal Neurons

Cong L. Li, Aruna Sathyamurthy, Anna Oldenborg, Dharmesh Tank, Narendrakumar Ramanan

J Neurosci. 2014 Mar 12; 34(11): 4027–4042. doi: 10.1523/JNEUROSCI.4677-12.2014

PMCID:: PMC6705271

Abstract Article PDF–4.2M

Select item 663412113.

Impact of Actin Filament Stabilization on Adult Hippocampal and Olfactory Bulb Neurogenesis

Golo Kronenberg, Karen Gertz, Tina Baldinger, Imke Kirste, Sarah Eckart, Ferah Yildirim, Shengbo Ji, Isabella Heuser, Helmut Schröck, Heide Hörtnagl, Reinhard Sohr, Pierre Chryso Djoufack, René Jüttner, Rainer Glass, Ingo Przesdzing, Jitender Kumar, Dorette Freyer, Rainer Hellweg, Helmut Kettenmann, Klaus Benno Fink, Matthias Endres

J Neurosci. 2010 Mar 3; 30(9): 3419–3431. doi: 10.1523/JNEUROSCI.4231-09.2010

PMCID:: PMC6634121

Abstract Article PDF–3.6M

Select item 659678014.

LINGO-1 Regulates Oligodendrocyte Differentiation through the Cytoplasmic Gelsolin Signaling Pathway

Zhaohui Shao, Xinhua Lee, Guanrong Huang, Guoqing Sheng, Christopher E. Henderson, Daniel Louvard, Jiho Sohn, Blake Pepinsky, Sha Mi

J Neurosci. 2017 Mar 22; 37(12): 3127–3137. doi: 10.1523/JNEUROSCI.3722-16.2017

Retraction in:: J Neurosci. 2018 Nov 14; 38(46): 10017.

PMCID:: PMC6596780

Abstract Article

Select item 655472315.

Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca²⁺/CaM) and CaM Kinase II (CaMKII) Binding Partner

Paul R. Evans, Kyle J. Gerber, Eric B. Dammer, Duc M. Duong, Devrishi Goswami, Daniel J. Lustberg, Juan Zou, Jenny J. Yang, Serena M. Dudek, Patrick R. Griffin, Nicholas T. Seyfried, John R. Hepler

J Proteome Res. Author manuscript; available in PMC 2019 Jun 7.

Published in final edited form as: J Proteome Res. 2018 Apr 6; 17(4): 1700–1711. Published online 2018 Mar 20. doi: 10.1021/acs.jproteome.8b00027

PMCID:: PMC6554723

Abstract Article PDF–2.0M

Select item 630060816.

PI3Kα-regulated gelsolin activity is a critical determinant of cardiac cytoskeletal remodeling and heart disease

Vaibhav B. Patel, Pavel Zhabyeyev, Xueyi Chen, Faqi Wang, Manish Paul, Dong Fan, Brent A. McLean, Ratnadeep Basu, Pu Zhang, Saumya Shah, John F. Dawson, W. Glen Pyle, Mousumi Hazra, Zamaneh Kassiri, Saugata Hazra, Bart Vanhaesebroeck, Christopher A. McCulloch, Gavin Y. Oudit

Nat Commun. 2018; 9: 5390. Published online 2018 Dec 19. doi: 10.1038/s41467-018-07812-8

PMCID:: PMC6300608

Abstract Article PDF–4.9M

Select item 612095617.

Plasma gelsolin promotes re-epithelialization

J. Wittmann, J. Dieckow, H. Schröder, U. Hampel, F. Garreis, C. Jacobi, A. Milczarek, K. L. Hsieh, B. Pulli, J. W. Chen, S. Hoogeboom, L. Bräuer, F. P. Paulsen, S. Schob, M. Schicht

Sci Rep. 2018; 8: 13140. Published online 2018 Sep 3. doi: 10.1038/s41598-018-31441-2

PMCID:: PMC6120956

Abstract Article PDF–5.4M

Select item 592777118.

Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy

Gian-Luca McLelland, Thomas Goiran, Wei Yi, Geneviève Dorval, Carol X Chen, Nadine D Lauinger, Andrea I Krahn, Sepideh Valimehr, Aleksandar Rakovic, Isabelle Rouiller, Thomas M Durcan, Jean-François Trempe, Edward A Fon

eLife. 2018; 7: e32866. Published online 2018 Apr 20. doi: 10.7554/eLife.32866

PMCID:: PMC5927771

Abstract Article PDF–9.1M

Select item 584616319.

An N-terminal motif unique to primate tau enables differential protein–protein interactions

Kristie Stefanoska, Alexander Volkerling, Josefine Bertz, Anne Poljak, Yazi D. Ke, Lars M. Ittner, Arne Ittner

J Biol Chem. 2018 Mar 9; 293(10): 3710–3719. Published online 2018 Jan 30. doi: 10.1074/jbc.RA118.001784

PMCID:: PMC5846163

Abstract Article PDF–1.2M

Select item 580795720.

Actin-Depolymerizing Factor and Cofilin-1 Have Unique and Overlapping Functions in Regulating Intestinal Epithelial Junctions and Mucosal Inflammation

Dongdong Wang, Nayden G. Naydenov, Alex Feygin, Somesh Baranwal, John F. Kuemmerle, Andrei I. Ivanov

Am J Pathol. 2016 Apr; 186(4): 844–858. doi: 10.1016/j.ajpath.2015.11.023

PMCID:: PMC5807957

Abstract Article

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