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Select item 109849541.

Identification of ASF1A and HJURP by global H3–H4 histone chaperone analysis as a prognostic two-gene model in hepatocellular carcinoma

Yongkang Liu, Shihui Liu, Rui Jing, Congcong Li, Yongqi Guo, Zhiye Cai, Pei Xi, Penggao Dai, Lintao Jia, Hongli Zhu, Xiang Zhang

Sci Rep. 2024; 14: 7666. Published online 2024 Apr 1. doi: 10.1038/s41598-024-58368-1

Correction in:: Sci Rep. 2024; 14: 20726.

PMCID:: PMC10984954

Abstract Article PDF–5.2M

Select item 105658762.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 102374223.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 97696984.

A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor

Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth

Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.

Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841

PMCID:: PMC9769698

Abstract Article PDF–2.7M

Select item 93434555.

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis

Natalie Vaughan, Nico Scholz, Catherine Lindon, Julien D. F. Licchesi

Sci Rep. 2022; 12: 13160. Published online 2022 Aug 1. doi: 10.1038/s41598-022-16965-y

PMCID:: PMC9343455

Abstract Article PDF–3.7M

Select item 91197366.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 90338777.

HJURP regulates cell proliferation and chemo-resistance via YAP1/NDRG1 transcriptional axis in triple-negative breast cancer

Misha Mao, Yunlu Jia, Yongxia Chen, Jingjing Yang, Ling Xu, Xun Zhang, Jichun Zhou, Zhaoqing Li, Cong Chen, Siwei Ju, Linbo Wang

Cell Death Dis. 2022 Apr; 13(4): 396. Published online 2022 Apr 22. doi: 10.1038/s41419-022-04833-6

PMCID:: PMC9033877

Abstract Article PDF–7.0M

Select item 87690728.

Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome

Caroline Benz, Muhammad Ali, Izabella Krystkowiak, Leandro Simonetti, Ahmed Sayadi, Filip Mihalic, Johanna Kliche, Eva Andersson, Per Jemth, Norman E Davey, Ylva Ivarsson

Mol Syst Biol. 2022 Jan; 18(1): e10584. Published online 2022 Jan 19. doi: 10.15252/msb.202110584

PMCID:: PMC8769072

Abstract Article PDF–2.9M

Select item 85664739.

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma

Tatenda Mahlokozera, Bhuvic Patel, Hao Chen, Patrick Desouza, Xuan Qu, Diane D. Mao, Daniel Hafez, Wei Yang, Rukayat Taiwo, Mounica Paturu, Afshin Salehi, Amit D. Gujar, Gavin P. Dunn, Nima Mosammaparast, Allegra A. Petti, Hiroko Yano, Albert H. Kim

Nat Commun. 2021; 12: 6321. Published online 2021 Nov 3. doi: 10.1038/s41467-021-26653-6

PMCID:: PMC8566473

Abstract Article PDF–2.7M

Select item 835296410.

Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer

Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger

Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y

PMCID:: PMC8352964

Abstract Article PDF–4.5M

Select item 818482411.

HJURP promotes proliferation in prostate cancer cells through increasing CDKN1A degradation via the GSK3β/JNK signaling pathway

Wenjie Lai, Weian Zhu, Chutian Xiao, Xiaojuan Li, Yu Wang, Yuefu Han, Jiayu Zheng, Yingqiu Li, Mingqiang Li, Xingqiao Wen

Cell Death Dis. 2021 Jun; 12(6): 583. Published online 2021 Jun 7. doi: 10.1038/s41419-021-03870-x

PMCID:: PMC8184824

Abstract Article PDF–3.7M

Select item 816503012.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 775711913.

Promiscuous Histone Mis-Assembly Is Actively Prevented by Chaperones

Haiqing Zhao, David Winogradoff, Minh Bui, Yamini Dalal, Garegin A. Papoian

J Am Chem Soc. Author manuscript; available in PMC 2020 Dec 23.

Published in final edited form as: J Am Chem Soc. 2016 Oct 12; 138(40): 13207–13218. Published online 2016 Aug 12. doi: 10.1021/jacs.6b05355

PMCID:: PMC7757119

Abstract Article PDF–2.0M

Select item 766271214.

Prognostic Relevance of HJURP Expression in Patients with Surgically Resected Colorectal Cancer

Dong Hyun Kang, Jongsoo Woo, Hyeongjoo Kim, Soo Youn Kim, Sanghee Ji, Gunn Jaygal, Tae Sung Ahn, Han Jo Kim, Hyoung Jong Kwak, Chang-Jin Kim, Moo-Jun Baek, Dongjun Jeong

Int J Mol Sci. 2020 Nov; 21(21): 7928. Published online 2020 Oct 26. doi: 10.3390/ijms21217928

PMCID:: PMC7662712

Abstract Article PDF–1.9M

Select item 741748015.

BAG5 Promotes Alpha-Synuclein Oligomer Formation and Functionally Interacts With the Autophagy Adaptor Protein p62

Erik L. Friesen, Yu Tong Zhang, Rebecca Earnshaw, Mitch L. De Snoo, Darren M. O’Hara, Victoria Agapova, Hien Chau, Sophie Ngana, Kevin S. Chen, Lorraine V. Kalia, Suneil K. Kalia

Front Cell Dev Biol. 2020; 8: 716. Published online 2020 Aug 4. doi: 10.3389/fcell.2020.00716

PMCID:: PMC7417480

Abstract Article PDF–1.8M

Select item 677813716.

The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis

Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino

Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9

PMCID:: PMC6778137

Abstract Article PDF–7.8M

Select item 676198717.

CENP-A Ubiquitylation Is Indispensable to Cell Viability

Yohei Niikura, Risa Kitagawa, Lei Fang, Katsumi Kitagawa

Dev Cell. Author manuscript; available in PMC 2020 Sep 23.

Published in final edited form as: Dev Cell. 2019 Sep 23; 50(6): 683–689.e6. doi: 10.1016/j.devcel.2019.07.015

PMCID:: PMC6761987

Abstract Article PDF–1.4M

Select item 673131918.

Mechanism of centromere recruitment of the CENP-A chaperone HJURP and its implications for centromere licensing

Dongqing Pan, Kai Walstein, Annika Take, David Bier, Nadine Kaiser, Andrea Musacchio

Nat Commun. 2019; 10: 4046. Published online 2019 Sep 6. doi: 10.1038/s41467-019-12019-6

PMCID:: PMC6731319

Abstract Article PDF–6.7M

Select item 634139019.

Holliday junction recognition protein interacts with and specifies the centromeric assembly of CENP-T

Mingrui Ding, Jiying Jiang, Fengrui Yang, Fan Zheng, Jingwen Fang, Qian Wang, Jianyu Wang, William Yao, Xu Liu, Xinjiao Gao, McKay Mullen, Ping He, Cathy Rono, Xia Ding, Jingjun Hong, Chuanhai Fu, Xing Liu, Xuebiao Yao

J Biol Chem. 2019 Jan 18; 294(3): 968–980. Published online 2018 Nov 20. doi: 10.1074/jbc.RA118.004688

PMCID:: PMC6341390

Abstract Article PDF–3.5M

Select item 620335620.

HJURP antagonizes CENP-A mislocalization driven by the H3.3 chaperones HIRA and DAXX

Jonathan Nye, David Sturgill, Rajbir Athwal, Yamini Dalal

PLoS One. 2018; 13(10): e0205948. Published online 2018 Oct 26. doi: 10.1371/journal.pone.0205948

Correction in:: PLoS One. 2018; 13(11): e0207631.

PMCID:: PMC6203356

Abstract Article PDF–2.0M

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