PMC Links for GEO Profiles (Select 21255820) - PMC

Daniel B. McClatchy, Nam-Kyung Yu, Salvador Martínez-Bartolomé, Reesha Patel, Alexander R. Pelletier, Mathieu Lavalle-Adam, Susan B. Powell, Marissa Roberto, John R. Yates

ACS Chem Neurosci. Author manuscript; available in PMC 2019 Apr 17.

Published in final edited form as: ACS Chem Neurosci. 2018 Dec 19; 9(12): 3072–3085. Published online 2018 Aug 13. doi: 10.1021/acschemneuro.8b00284

PMCID:: PMC6374210

Abstract Article PDF–1.4M

Select item 63650794.

miR-335 promotes stress granule formation to inhibit apoptosis by targeting ROCK2 in acute ischemic stroke

Wenwen Si, Shanyu Ye, Zhenxing Ren, Xin Liu, Zimei Wu, Yi Li, Jianhong Zhou, Saixia Zhang, Yiwei Li, Rudong Deng, Dongfeng Chen

Int J Mol Med. 2019 Mar; 43(3): 1452–1466. Published online 2019 Jan 22. doi: 10.3892/ijmm.2019.4073

PMCID:: PMC6365079

Abstract Article PDF–3.5M

Select item 62356745.

Neuroprotection Mediated by Upregulation of Endothelial Nitric Oxide Synthase in Rho-Associated, Coiled-Coil-Containing Kinase 2 Deficient Mice

Yukio Hiroi, Kensuke Noma, Hyung-Hwan Kim, Nikola Sladojevic, Corey E. Tabit, Yuxin Li, Guray Soydan, Salvatore Salomone, Michael A. Moskowitz, James K. Liao

Circ J. Author manuscript; available in PMC 2018 Nov 14.

Published in final edited form as: Circ J. 2018 Mar 23; 82(4): 1195–1204. Published online 2018 Jan 19. doi: 10.1253/circj.CJ-17-0732

PMCID:: PMC6235674

Abstract Article PDF–892K

Select item 54993696.

Fibroblast deletion of ROCK2 attenuates cardiac hypertrophy, fibrosis, and diastolic dysfunction

Toru Shimizu, Nikhil Narang, Phetcharat Chen, Brian Yu, Maura Knapp, Jyothi Janardanan, John Blair, James K. Liao

JCI Insight. 2017 Jul 6; 2(13): e93187. Published online 2017 Jul 6. doi: 10.1172/jci.insight.93187

PMCID:: PMC5499369

Abstract Article PDF–3.6M

Select item 54312087.

Role of differentially expressed microRNA-139-5p in the regulation of phenotypic internal anal sphincter smooth muscle tone

Jagmohan Singh, Ipsita Mohanty, Sankar Addya, Benjamin Phillips, Hwan Mee Yong, Steven S. An, Raymond B. Penn, Satish Rattan

Sci Rep. 2017; 7: 1477. Published online 2017 May 3. doi: 10.1038/s41598-017-01550-5

PMCID:: PMC5431208

Abstract Article PDF–2.7M

Select item 51453048.

Rescue treatment with a Rho-kinase inhibitor normalizes right ventricular function and reverses remodeling in juvenile rats with chronic pulmonary hypertension

Emily Z. Xu, Crystal Kantores, Julijana Ivanovska, Doreen Engelberts, Brian P. Kavanagh, Patrick J. McNamara, Robert P. Jankov

Am J Physiol Heart Circ Physiol. Author manuscript; available in PMC 2016 Dec 8.

Published in final edited form as: Am J Physiol Heart Circ Physiol. 2010 Dec; 299(6): H1854–H1864. Published online 2010 Oct 1. doi: 10.1152/ajpheart.00595.2010

PMCID:: PMC5145304

Abstract Article PDF–1.3M

Select item 47329139.

Valve endothelial cell-derived Tgfβ1 signaling promotes nuclear localization of Sox9 in interstitial cells associated with attenuated calcification

Danielle J Huk, Blair F. Austin, Tori E. Horne, Robert B. Hinton, William C. Ray, Donald D. Heistad, Joy Lincoln

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2017 Feb 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2016 Feb; 36(2): 328–338. Published online 2015 Dec 3. doi: 10.1161/ATVBAHA.115.306091

PMCID:: PMC4732913

Abstract Article PDF–2.3M

Select item 450970010.

Chronic Rho-kinase inhibition improves left ventricular contractile dysfunction in early type-1 diabetes by increasing myosin cross-bridge extension

Mark T Waddingham, Amanda J Edgley, Alberto Astolfo, Tadakatsu Inagaki, Yutaka Fujii, Cheng-Kun Du, Dong-Yun Zhan, Hirotsugu Tsuchimochi, Naoto Yagi, Darren J Kelly, Mikiyasu Shirai, James T Pearson

Cardiovasc Diabetol. 2015; 14: 92. Published online 2015 Jul 22. doi: 10.1186/s12933-015-0256-6

PMCID:: PMC4509700

Abstract Article PDF–2.1M

Select item 450889511.

ROCK1 and 2 differentially regulate actomyosin organization to drive cell and synaptic polarity

Karen A. Newell-Litwa, Mathilde Badoual, Hannelore Asmussen, Heather Patel, Leanna Whitmore, Alan Rick Horwitz

J Cell Biol. 2015 Jul 20; 210(2): 225–242. doi: 10.1083/jcb.201504046

PMCID:: PMC4508895

Abstract Article PDF–4.1M

Select item 450302012.

A modified “double-hit” induced acute lung injury model in rats and protective effects of tetramethylpyrazine on the injury via Rho/ROCK pathway

Shidi Zhao, Yong Zhang, Qianfen Chen, Shuying Dong, Gaofeng Zhang, Jia Li, Xilan Yang, Yan Li

Int J Clin Exp Pathol. 2015; 8(5): 4581–4587. Published online 2015 May 1.

PMCID:: PMC4503020

Abstract Article PDF–1.2M

Select item 437685013.

Tumor Necrosis Factor Disrupts Claudin-5 Endothelial Tight Junction Barriers in Two Distinct NF-κB-Dependent Phases

Paul R. Clark, Richard K. Kim, Jordan S. Pober, Martin S. Kluger

PLoS One. 2015; 10(3): e0120075. Published online 2015 Mar 27. doi: 10.1371/journal.pone.0120075

PMCID:: PMC4376850

Abstract Article PDF–7.3M

Select item 404792014.

ROCK2 is a major regulator of axonal degeneration, neuronal death and axonal regeneration in the CNS

J C Koch, L Tönges, E Barski, U Michel, M Bähr, P Lingor

Cell Death Dis. 2014 May; 5(5): e1225. Published online 2014 May 15. doi: 10.1038/cddis.2014.191

PMCID:: PMC4047920

Abstract Article PDF–3.2M

Select item 389648815.

Complex Regulation of PKCβ2 and PDK-1/AKT by ROCK2 in Diabetic Heart

Guorong Lin, Roger W. Brownsey, Kathleen M. MacLeod

PLoS One. 2014; 9(1): e86520. Published online 2014 Jan 20. doi: 10.1371/journal.pone.0086520

PMCID:: PMC3896488

Abstract Article PDF–4.4M

Select item 385003616.

Pharmacologic Inhibition of ROCK2 Suppresses Amyloid-β Production in an Alzheimer's Disease Mouse Model

Jeremy H. Herskowitz, Yangbo Feng, Alexa L. Mattheyses, Chadwick M. Hales, Lenora A. Higginbotham, Duc M. Duong, Thomas J. Montine, Juan C. Troncoso, Madhav Thambisetty, Nicholas T. Seyfried, Allan I. Levey, James J. Lah

J Neurosci. 2013 Dec 4; 33(49): 19086–19098. doi: 10.1523/JNEUROSCI.2508-13.2013