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Items: 1 to 20 of 22

1.
Orphan receptor GPR158 serves as a metabotropic glycine receptor: mGlyR
Thibaut Laboute, Stefano Zucca, Matthew Holcomb, Dipak N. Patil, Christina Garza, Brittany A. Wheatley, Raktim N. Roy, Stefano Forli, Kirill A. Martemyanov
Science. Author manuscript; available in PMC 2024 Mar 31.
Published in final edited form as: Science. 2023 Mar 31; 379(6639): 1352–1358. Published online 2023 Mar 30. doi: 10.1126/science.add7150
PMCID:
PMC10751545
AbstractArticlePDF–2.3M
2.
Cryo-EM structure of human GPR158 receptor coupled to the RGS7-Gβ5 signaling complex
Dipak N. Patil, Shikha Singh, Thibaut Laboute, Timothy S. Strutzenberg, Xingyu Qiu, Di Wu, Scott J. Novick, Carol V. Robinson, Patrick R. Griffin, John F. Hunt, Tina Izard, Appu K. Singh, Kirill A. Martemyanov
Science. Author manuscript; available in PMC 2023 Jan 7.
Published in final edited form as: Science. 2022 Jan 7; 375(6576): 86–91. Published online 2021 Nov 18. doi: 10.1126/science.abl4732
PMCID:
PMC8926151
AbstractArticlePDF–1.0M
3.
Structure of the class C orphan GPCR GPR158 in complex with RGS7-Gβ5
Eunyoung Jeong, Yoojoong Kim, Jihong Jeong, Yunje Cho
Nat Commun. 2021; 12: 6805. Published online 2021 Nov 23. doi: 10.1038/s41467-021-27147-1
PMCID:
PMC8611064
AbstractArticlePDF–2.7M
4.
Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry
Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang
Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118
PMCID:
PMC8364181
AbstractArticlePDF–3.0M
5.
Immunohistochemical validation of COL3A1, GPR158 and PITHD1 as prognostic biomarkers in early-stage ovarian carcinomas
Hanna Engqvist, Toshima Z. Parris, Anikó Kovács, Szilárd Nemes, Elisabeth Werner Rönnerman, Shahin De Lara, Jana Biermann, Karin Sundfeldt, Per Karlsson, Khalil Helou
BMC Cancer. 2019; 19: 928. Published online 2019 Sep 18. doi: 10.1186/s12885-019-6084-4
PMCID:
PMC6751742
AbstractArticlePDF–1.6M
6.
TNRC6 proteins modulate hepatitis C virus replication by spatially regulating the binding of miR-122/Ago2 complexes to viral RNA
You Li, Li Wang, Efraín E Rivera-Serrano, Xian Chen, Stanley M Lemon
Nucleic Acids Res. 2019 Jul 9; 47(12): 6411–6424. Published online 2019 Apr 18. doi: 10.1093/nar/gkz278
PMCID:
PMC6614814
AbstractArticlePDF–4.9M
7.
GPR158 in the Visual System: Homeostatic Role in Regulation of Intraocular Pressure
Tatsuo Itakura, Andrew Webster, Shravan K. Chintala, Yuchen Wang, Jose M. Gonzalez, Jr., J.C. Tan, Janice A. Vranka, Ted Acott, Cheryl Mae Craft, Maria E. Sibug Saber, Shinwu Jeong, W. Daniel Stamer, Kirill A. Martemyanov, M. Elizabeth Fini
J Ocul Pharmacol Ther. 2019 May 1; 35(4): 203–215. Published online 2019 May 14. doi: 10.1089/jop.2018.0135
PMCID:
PMC6533807
AbstractArticlePDF–31M
8.
The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2
Joanna R. Kovalski, Aparna Bhaduri, Ashley M. Zehnder, Poornima H. Neela, Yonglu Che, Glenn G. Wozniak, Paul A. Khavari
Mol Cell. Author manuscript; available in PMC 2020 Feb 21.
Published in final edited form as: Mol Cell. 2019 Feb 21; 73(4): 830–844.e12. Published online 2019 Jan 10. doi: 10.1016/j.molcel.2018.12.001
PMCID:
PMC6386588
AbstractArticlePDF–1.7M
9.
VIRMA mediates preferential m6A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation
Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu
Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0
PMCID:
PMC5826926
AbstractArticlePDF–2.3M
10.
Orphan receptor GPR158 controls stress-induced depression
Laurie P Sutton, Cesare Orlandi, Chenghui Song, Won Chan Oh, Brian S Muntean, Keqiang Xie, Alice Filippini, Xiangyang Xie, Rachel Satterfield, Jazmine D W Yaeger, Kenneth J Renner, Samuel M Young, Jr, Baoji Xu, Hyungbae Kwon, Kirill A Martemyanov
eLife. 2018; 7: e33273. Published online 2018 Feb 8. doi: 10.7554/eLife.33273
PMCID:
PMC5823542
AbstractArticlePDF–3.6M
11.
Gpr158 mediates osteocalcin’s regulation of cognition
Lori Khrimian, Arnaud Obri, Mariana Ramos-Brossier, Audrey Rousseaud, Stéphanie Moriceau, Anne-Sophie Nicot, Paula Mera, Stylianos Kosmidis, Theodoros Karnavas, Frederic Saudou, Xiao-Bing Gao, Franck Oury, Eric Kandel, Gerard Karsenty
J Exp Med. 2017 Oct 2; 214(10): 2859–2873. doi: 10.1084/jem.20171320
PMCID:
PMC5626410
AbstractArticlePDF–2.0M
12.
A Genome-Wide Association Study Using a Custom Genotyping Array Identifies Variants in GPR158 Associated With Reduced Energy Expenditure in American Indians
Paolo Piaggi, Ivica Masindova, Yunhua L. Muller, Josep Mercader, Gregory B. Wiessner, Peng Chen, SIGMA Type 2 Diabetes Consortium, Sayuko Kobes, Wen-Chi Hsueh, Milliejoan Mongalo, William C. Knowler, Jonathan Krakoff, Robert L. Hanson, Clifton Bogardus, Leslie J. Baier
Diabetes. 2017 Aug; 66(8): 2284–2295. Published online 2017 May 5. doi: 10.2337/db16-1565
PMCID:
PMC5521859
AbstractArticlePDF–1.4M
13.
Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing
Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown
Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114
PMCID:
PMC5495225
AbstractArticlePDF–1.3M
14.
Orphan Receptor GPR158 Is an Allosteric Modulator of RGS7 Catalytic Activity with an Essential Role in Dictating Its Expression and Localization in the Brain
Cesare Orlandi, Keqiang Xie, Ikuo Masuho, Ana Fajardo-Serrano, Rafael Lujan, Kirill A. Martemyanov
J Biol Chem. 2015 May 29; 290(22): 13622–13639. Published online 2015 Mar 19. doi: 10.1074/jbc.M115.645374
PMCID:
PMC4447942
AbstractArticlePDF–3.6M
15.
Expression and Functional Role of Orphan Receptor GPR158 in Prostate Cancer Growth and Progression
Nitin Patel, Tatsuo Itakura, Shinwu Jeong, Chun-Peng Liao, Pradip Roy-Burman, Ebrahim Zandi, Susan Groshen, Jacek Pinski, Gerhard A. Coetzee, Mitchell E. Gross, M. Elizabeth Fini
PLoS One. 2015; 10(2): e0117758. Published online 2015 Feb 18. doi: 10.1371/journal.pone.0117758
PMCID:
PMC4333349
AbstractArticlePDF–5.4M
16.
Genome Wide Association Study (GWAS) of Chagas Cardiomyopathy in Trypanosoma cruzi Seropositive Subjects
Xutao Deng, Ester C. Sabino, Edecio Cunha-Neto, Antonio L. Ribeiro, Barbara Ianni, Charles Mady, Michael P. Busch, Mark Seielstad, the REDSII Chagas study group from the NHLBI Retrovirus Epidemiology Donor Study-II (REDS-II), International Component
PLoS One. 2013; 8(11): e79629. Published online 2013 Nov 20. doi: 10.1371/journal.pone.0079629
PMCID:
PMC3854669
AbstractArticlePDF–408K
17.
GPR158, an Orphan Member of G Protein-Coupled Receptor Family C: Glucocorticoid-Stimulated Expression and Novel Nuclear Role
Nitin Patel, Tatsuo Itakura, Jose M. Gonzalez, Jr, Stephen G. Schwartz, M. Elizabeth Fini
PLoS One. 2013; 8(2): e57843. Published online 2013 Feb 25. doi: 10.1371/journal.pone.0057843
PMCID:
PMC3581496
AbstractArticlePDF–1.9M
18.
Loci Associated with N-Glycosylation of Human Immunoglobulin G Show Pleiotropy with Autoimmune Diseases and Haematological Cancers
Gordan Lauc, Jennifer E. Huffman, Maja Pučić, Lina Zgaga, Barbara Adamczyk, Ana Mužinić, Mislav Novokmet, Ozren Polašek, Olga Gornik, Jasminka Krištić, Toma Keser, Veronique Vitart, Blanca Scheijen, Hae-Won Uh, Mariam Molokhia, Alan Leslie Patrick, Paul McKeigue, Ivana Kolčić, Ivan Krešimir Lukić, Olivia Swann, Frank N. van Leeuwen, L. Renee Ruhaak, Jeanine J. Houwing-Duistermaat, P. Eline Slagboom, Marian Beekman, Anton J. M. de Craen, André M. Deelder, Qiang Zeng, Wei Wang, Nicholas D. Hastie, Ulf Gyllensten, James F. Wilson, Manfred Wuhrer, Alan F. Wright, Pauline M. Rudd, Caroline Hayward, Yurii Aulchenko, Harry Campbell, Igor Rudan
PLoS Genet. 2013 Jan; 9(1): e1003225. Published online 2013 Jan 31. doi: 10.1371/journal.pgen.1003225
PMCID:
PMC3561084
AbstractArticlePDF–1.0M
19.
Genome-Wide Association Study of Antibody Response to Smallpox Vaccine
Inna G. Ovsyannikova, Richard B. Kennedy, Megan O'Byrne, Robert M. Jacobson, V. Shane Pankratz, Gregory A. Poland
Vaccine. Author manuscript; available in PMC 2013 Jun 13.
Published in final edited form as: Vaccine. 2012 Jun 13; 30(28): 4182–4189. Published online 2012 Apr 25. doi: 10.1016/j.vaccine.2012.04.055
PMCID:
PMC3367131
AbstractArticlePDF–1.3M
20.
Personalized Smoking Cessation: Interactions between Nicotine Dose, Dependence and Quit-Success Genotype Score
Jed E Rose, Frédérique M Behm, Tomas Drgon, Catherine Johnson, George R Uhl
Mol Med. 2010 Jul-Aug; 16(7-8): 247–253. Published online 2010 Mar 17. doi: 10.2119/molmed.2009.00159
Correction in:
Mol Med. 2012; 18(1): 729.
PMCID:
PMC2896464
AbstractArticlePDF–2.4M

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