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Select item 112135171.

GPR124 regulates murine brain embryonic angiogenesis and BBB formation by an intracellular domain-independent mechanism

Kanako Yuki, Mario Vallon, Jie Ding, Cara C. Rada, Alan T. Tang, José G. Vilches-Moure, Aaron K. McCormick, Maria F. Henao Echeverri, Samira Alwahabi, Barbara M. Braunger, Süleyman Ergün, Mark L. Kahn, Calvin J. Kuo

Development. 2024 Jun 1; 151(11): dev202794. Published online 2024 Jun 17. doi: 10.1242/dev.202794

PMCID:: PMC11213517

Abstract Article

Select item 111159582.

Participation of the second extracellular loop of claudin-5 in paracellular tightening against ions, small and large molecules

Christian Piehl, Jörg Piontek, Jimmi Cording, Hartwig Wolburg, Ingolf E. Blasig

Cell Mol Life Sci. 2010 Jun; 67(12): 2131–2140. Published online 2010 Mar 24. doi: 10.1007/s00018-010-0332-8

PMCID:: PMC11115958

Abstract Article PDF–701K

Select item 111053303.

Tight junction proteins at the blood–brain barrier: far more than claudin-5

Philipp Berndt, Lars Winkler, Jimmi Cording, Olga Breitkreuz-Korff, André Rex, Sophie Dithmer, Valentina Rausch, Rosel Blasig, Matthias Richter, Anje Sporbert, Hartwig Wolburg, Ingolf E. Blasig, Reiner F. Haseloff

Cell Mol Life Sci. 2019 May; 76(10): 1987–2002. Published online 2019 Feb 7. doi: 10.1007/s00018-019-03030-7

PMCID:: PMC11105330

Abstract Article PDF–2.4M

Select item 108553384.

Canonical and Non-Canonical Localization of Tight Junction Proteins during Early Murine Cranial Development

Shermin Mak, Annette Hammes

Int J Mol Sci. 2024 Feb; 25(3): 1426. Published online 2024 Jan 24. doi: 10.3390/ijms25031426

PMCID:: PMC10855338

Abstract Article PDF–3.7M

Select item 107742305.

Heterogeneity of endothelial VE-PTP downstream polarization, Tie2 activation, junctional claudin-5, and permeability in the aorta and vena cava

Peter Baluk, Keisuke Shirakura, Dietmar Vestweber, Donald M. McDonald

Cell Tissue Res. 2024; 395(1): 81–103. Published online 2023 Nov 30. doi: 10.1007/s00441-023-03844-9

PMCID:: PMC10774230

Abstract Article PDF–13M

Select item 106264696.

PRELP secreted from mural cells protects the function of blood brain barrier through regulation of endothelial cell-cell integrity

Hongorzul Davaapil, Jack Hopkins, Nadia Bonnin, Vasiliki Papadaki, Alex Leung, Hirofumi Kosuge, Takumi Tashima, Makoto Nakakido, Ryohei Sekido, Kouhei Tsumoto, Mandeep S. Sagoo, Shin-Ichi Ohnuma

Front Cell Dev Biol. 2023; 11: 1147625. Published online 2023 Oct 23. doi: 10.3389/fcell.2023.1147625

PMCID:: PMC10626469

Abstract Article PDF–4.5M

Select item 103933457.

Ultrasound-guided transfection of claudin-5 improves lung endothelial barrier function in lung injury without impairing innate immunity

Rajiv Sanwal, Victoria Mintsopoulos, Mihails Ditmans, Alice Lang, Elyse Latreille, Siavash Ghaffari, Negar Khosraviani, Raffi Karshafian, Howard Leong-Poi, David M. Hwang, Laurent Brochard, Alberto Goffi, Arthur S. Slutsky, Warren L. Lee

Am J Physiol Lung Cell Mol Physiol. 2023 Aug 1; 325(2): L135–L142. Published online 2023 Jun 13. doi: 10.1152/ajplung.00107.2023

PMCID:: PMC10393345

Abstract Article

Select item 102877008.

Maternal NAT10 orchestrates oocyte meiotic cell-cycle progression and maturation in mice

Xue Jiang, Yu Cheng, Yuzhang Zhu, Caoling Xu, Qiaodan Li, Xuemei Xing, Wenqing Li, Jiaqi Zou, Lan Meng, Muhammad Azhar, Yuzhu Cao, Xianhong Tong, Weibing Qin, Xiaoli Zhu, Jianqiang Bao

Nat Commun. 2023; 14: 3729. Published online 2023 Jun 22. doi: 10.1038/s41467-023-39256-0

PMCID:: PMC10287700

Abstract Article PDF–13M

Select item 102127169.

Endothelial Arid1a deletion disrupts the balance among angiogenesis, neurogenesis and gliogenesis in the developing brain

Yuanyuan Wang, Libo Su, Wenwen Wang, Jinyue Zhao, Yanyan Wang, Sihan Li, Yan Liu, Renjie Chai, Xin Li, Zhaoqian Teng, Changmei Liu, Baoyang Hu, Fen Ji, Jianwei Jiao

Cell Prolif. 2023 May; 56(5): e13447. Published online 2023 Mar 13. doi: 10.1111/cpr.13447

PMCID:: PMC10212716

Abstract Article PDF–4.7M

Select item 1004482510.

The CLDN5 gene at the blood-brain barrier in health and disease

Yosuke Hashimoto, Chris Greene, Arnold Munnich, Matthew Campbell

Fluids Barriers CNS. 2023; 20: 22. Published online 2023 Mar 28. doi: 10.1186/s12987-023-00424-5

PMCID:: PMC10044825

Abstract Article PDF–6.7M

Select item 979482411.

Single-cell transcriptomic analysis identifies murine heart molecular features at embryonic and neonatal stages

Wei Feng, Abha Bais, Haoting He, Cassandra Rios, Shan Jiang, Juan Xu, Cindy Chang, Dennis Kostka, Guang Li

Nat Commun. 2022; 13: 7960. Published online 2022 Dec 27. doi: 10.1038/s41467-022-35691-7

PMCID:: PMC9794824

Abstract Article PDF–17M

Select item 971371612.

Maternal immune activation leads to defective brain–blood vessels and intracerebral hemorrhages in male offspring

Marco Rasile, Eliana Lauranzano, Elisa Faggiani, Margherita M Ravanelli, Federico S Colombo, Filippo Mirabella, Irene Corradini, Maria L Malosio, Antonella Borreca, Elisa Focchi, Davide Pozzi, Toni Giorgino, Isabella Barajon, Michela Matteoli

EMBO J. 2022 Dec; 41(23): e111192. Published online 2022 Oct 31. doi: 10.15252/embj.2022111192

Correction in:: EMBO J. 2023 May; 42(10): e113890.

PMCID:: PMC9713716

Abstract Article PDF–3.2M

Select item 962426213.

Endothelial loss of ETS1 impairs coronary vascular development and leads to ventricular non-compaction

Lu Wang, Lizhu Lin, Hui Qi, Ju Chen, Paul Grossfeld

Circ Res. Author manuscript; available in PMC 2023 Aug 19.

Published in final edited form as: Circ Res. 2022 Aug 19; 131(5): 371–387. Published online 2022 Jul 27. doi: 10.1161/CIRCRESAHA.121.319955

PMCID:: PMC9624262

Abstract Article PDF–4.5M

Select item 934885014.

Claudin5 protects the peripheral endothelial barrier in an organ and vessel-type-specific manner

Mark Richards, Emmanuel Nwadozi, Sagnik Pal, Pernilla Martinsson, Mika Kaakinen, Marleen Gloger, Elin Sjöberg, Katarzyna Koltowska, Christer Betsholtz, Lauri Eklund, Sofia Nordling, Lena Claesson-Welsh

eLife. 2022; 11: e78517. Published online 2022 Jul 21. doi: 10.7554/eLife.78517

PMCID:: PMC9348850

Abstract Article PDF–14M

Select item 926281515.

Vitamin D Receptor Upregulates Tight Junction Protein Claudin-5 against Colitis-Associated Tumorigenesis

Yongguo Zhang, Shari Garrett, Robert E. Carroll, Yinglin Xia, Jun Sun

Mucosal Immunol. Author manuscript; available in PMC 2022 Sep 25.

Published in final edited form as: Mucosal Immunol. 2022 Apr; 15(4): 683–697. Published online 2022 Mar 25. doi: 10.1038/s41385-022-00502-1

PMCID:: PMC9262815

Abstract Article PDF–1.4M

Select item 913745216.

Excess Neuropeptides in Lung Signal through Endothelial Cells to Impair Gas Exchange

Jinhao Xu, Le Xu, Pengfei Sui, Jiyuan Chen, Esteban A. Moya, Patrick Hume, William J. Janssen, Jason M. Duran, Patricia Thistlethwaite, Aaron Carlin, Peter Gulleman, Brandon Banaschewski, Mary Kate Goldy, Jason X.-J. Yuan, Atul Malhotra, Gloria Pryhuber, Laura Crotty-Alexander, Gail Deutsch, Lisa R. Young, Xin Sun

Dev Cell. Author manuscript; available in PMC 2023 Apr 11.

Published in final edited form as: Dev Cell. 2022 Apr 11; 57(7): 839–853.e6. Published online 2022 Mar 17. doi: 10.1016/j.devcel.2022.02.023

PMCID:: PMC9137452

Abstract Article PDF–2.9M

Select item 908523517.

Claudin-5 relieves cognitive decline in Alzheimer’s disease mice through suppression of inhibitory GABAergic neurotransmission

Ning Zhu, Meidan Wei, Linguang Yuan, Xiaodan He, Chunli Chen, Aimin Ji, Guozeng Zhang

Aging (Albany NY) 2022 Apr 30; 14(8): 3554–3568. Published online 2022 Apr 26. doi: 10.18632/aging.204029

PMCID:: PMC9085235

Abstract Article PDF–5.9M

Select item 901041518.

Microvascular stabilization via blood-brain barrier regulation prevents seizure activity

Chris Greene, Nicole Hanley, Cristina R. Reschke, Avril Reddy, Maarja A. Mäe, Ruairi Connolly, Claire Behan, Eoin O’Keeffe, Isobel Bolger, Natalie Hudson, Conor Delaney, Michael A. Farrell, Donncha F. O’Brien, Jane Cryan, Francesca M. Brett, Alan Beausang, Christer Betsholtz, David C. Henshall, Colin P. Doherty, Matthew Campbell

Nat Commun. 2022; 13: 2003. Published online 2022 Apr 14. doi: 10.1038/s41467-022-29657-y

PMCID:: PMC9010415

Abstract Article PDF–4.5M

Select item 894830419.

Loss of CLDN5 in podocytes deregulates WIF1 to activate WNT signaling and contributes to kidney disease

Hui Sun, Hui Li, Jie Yan, Xiangdong Wang, Mengyuan Xu, Mingxia Wang, Baozhen Fan, Jieying Liu, Ninghua Lin, Xin Wang, Li Li, Shengtian Zhao, Yongfeng Gong

Nat Commun. 2022; 13: 1600. Published online 2022 Mar 24. doi: 10.1038/s41467-022-29277-6

PMCID:: PMC8948304

Abstract Article PDF–11M

Select item 878256820.

Myelinating Schwann cells and Netrin-1 control intra-nervous vascularization of the developing mouse sciatic nerve

Sonia Taïb, Noël Lamandé, Sabrina Martin, Fanny Coulpier, Piotr Topilko, Isabelle Brunet

eLife. 2022; 11: e64773. Published online 2022 Jan 12. doi: 10.7554/eLife.64773

PMCID:: PMC8782568

Abstract Article PDF–12M

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