PMC Links for GEO Profiles (Select 21385333) - PMC

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 105245434.

An astrocyte BMAL1-BAG3 axis protects against alpha-synuclein and tau pathology

Patrick W. Sheehan, Collin J. Nadarajah, Michael F. Kanan, Jessica N. Patterson, Brenna Novotny, Jennifer H. Lawrence, Melvin W. King, Logan Brase, Casey E. Inman, Carla M. Yuede, Jiyeon Lee, Tirth K. Patel, Oscar Harari, Bruno A. Benitez, Albert A. Davis, Erik S. Musiek

Neuron. Author manuscript; available in PMC 2024 Aug 2.

Published in final edited form as: Neuron. 2023 Aug 2; 111(15): 2383–2398.e7. Published online 2023 Jun 13. doi: 10.1016/j.neuron.2023.05.006

PMCID:: PMC10524543

Abstract Article PDF–4.2M

Select item 103336815.

Pancreatic beta-cell specific BAG3 knockout results in chronic hyperinsulinemia inducing insulin resistance

Verena Damiani, Alessia Lamolinara, Ilaria Cicalini, Maria Concetta Cufaro, Francesco Del Pizzo, Federica Di Marco, Piero Del Boccio, Beatrice Dufrusine, Michael Hahne, Rossano Lattanzio, Damiana Pieragostino, Manuela Iezzi, Massimo Federici, Maria Caterina Turco, Arianna Maiorana, Carlo Dionisi-Vici, Vincenzo De Laurenzi

Mol Metab. 2023 Aug; 74: 101752. Published online 2023 Jun 10. doi: 10.1016/j.molmet.2023.101752

PMCID:: PMC10333681

Abstract Article PDF–4.9M

Select item 102539366.

Skeletal Muscle-Specific Bis Depletion Leads to Muscle Dysfunction and Early Death Accompanied by Impairment in Protein Quality Control

Soon-Young Jung, Tae-Ryong Riew, Hye Hyeon Yun, Ji Hee Lim, Ji-Won Hwang, Sung Won Jung, Hong Lim Kim, Jae-Seon Lee, Mun-Yong Lee, Jeong-Hwa Lee

Int J Mol Sci. 2023 Jun; 24(11): 9635. Published online 2023 Jun 1. doi: 10.3390/ijms24119635

PMCID:: PMC10253936

Abstract Article PDF–6.1M

Select item 101644137.

Hematopoietic Stem Cells Preferentially Traffic Misfolded Proteins to Aggresomes and Depend on Aggrephagy to Maintain Protein Homeostasis

Bernadette A. Chua, Connor J. Lennan, Mary Jean Sunshine, Daniela Dreifke, Ashu Chawla, Eric J. Bennett, Robert A.J. Signer

Cell Stem Cell. Author manuscript; available in PMC 2024 Apr 6.

Published in final edited form as: Cell Stem Cell. 2023 Apr 6; 30(4): 460–472.e6. Published online 2023 Mar 21. doi: 10.1016/j.stem.2023.02.010

PMCID:: PMC10164413

Abstract Article PDF–2.1M

Select item 96469278.

Commentary: BAG3 as a mediator of endosome function and tau clearance

Heng Lin, Carol A. Deaton, Gail V. W. Johnson

Neuroscience. Author manuscript; available in PMC 2024 May 10.

Published in final edited form as: Neuroscience. 2023 May 10; 518: 4–9. Published online 2022 May 10. doi: 10.1016/j.neuroscience.2022.05.002

PMCID:: PMC9646927

Abstract Article PDF–531K

Select item 95026899.

BAG3 Attenuates Ischemia-Induced Skeletal Muscle Necroptosis in Diabetic Experimental Peripheral Artery Disease

Arul M. Mani, Karthik Dhanabalan, Victor Lamin, Thomas Wong, Madhu V. Singh, Ayotunde O. Dokun

Int J Mol Sci. 2022 Sep; 23(18): 10715. Published online 2022 Sep 14. doi: 10.3390/ijms231810715

PMCID:: PMC9502689

Abstract Article PDF–2.5M

Select item 948193310.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 947785311.

Transcriptional dynamics of murine motor neuron maturation in vivo and in vitro

Tulsi Patel, Jennifer Hammelman, Siaresh Aziz, Sumin Jang, Michael Closser, Theodore L. Michaels, Jacob A. Blum, David K. Gifford, Hynek Wichterle

Nat Commun. 2022; 13: 5427. Published online 2022 Sep 15. doi: 10.1038/s41467-022-33022-4

PMCID:: PMC9477853

Abstract Article PDF–7.4M

Select item 933250912.

BAG3 Alleviates Atherosclerosis by Inhibiting Endothelial-to-Mesenchymal Transition via Autophagy Activation

Hongtao Diao, Kaili Wu, Dingming Lan, Dongwei Wang, Jingjing Zhao, Bingying Huang, Xiaoqi Shao, Ruonan Wang, Huiling Tan, Xinyuan Tang, Meiling Yan, Yue Zhang

Genes (Basel) 2022 Aug; 13(8): 1338. Published online 2022 Jul 26. doi: 10.3390/genes13081338

PMCID:: PMC9332509

Abstract Article PDF–7.6M

Select item 908597213.

BAG3 regulation of Rab35 mediates the Endosomal Sorting Complexes Required for Transport /endolysosome pathway and tau clearance

Heng Lin, Maoping Tang, Changyi Ji, Peter Girardi, Gregor Cvetojevic, Daniel Chen, Shon A. Koren, Gail V. W. Johnson

Biol Psychiatry. Author manuscript; available in PMC 2023 Jul 1.

Published in final edited form as: Biol Psychiatry. 2022 Jul 1; 92(1): 10–24. Published online 2021 Nov 10. doi: 10.1016/j.biopsych.2021.10.024

PMCID:: PMC9085972

Abstract Article PDF–4.3M

Select item 878315114.

An unexpected role for BAG3 in regulating PARP1 ubiquitination in oxidative stress-related endothelial damage

Naijin Zhang, Ying Zhang, Wei Miao, Chuning Shi, Zihan Chen, Boquan Wu, Yuanming Zou, Qiushi Ma, Shilong You, Saien Lu, Xinyue Huang, Jingwei Liu, Jiaqi Xu, Liu Cao, Yingxian Sun

Redox Biol. 2022 Apr; 50: 102238. Published online 2022 Jan 17. doi: 10.1016/j.redox.2022.102238

PMCID:: PMC8783151

Abstract Article PDF–9.4M

Select item 868475015.

Strain-induced mechanoresponse depends on cell contractility and BAG3-mediated autophagy

Lukas Lövenich, Georg Dreissen, Christina Hoffmann, Jens Konrad, Ronald Springer, Jörg Höhfeld, Rudolf Merkel, Bernd Hoffmann

Mol Biol Cell. 2021 Oct 1; 32(20): ar9. doi: 10.1091/mbc.E21-05-0254

PMCID:: PMC8684750

Abstract Article PDF–7.6M

Select item 819610616.

Overexpression of human BAG3^P209L in mice causes restrictive cardiomyopathy

Kenichi Kimura, Astrid Ooms, Kathrin Graf-Riesen, Maithreyan Kuppusamy, Andreas Unger, Julia Schuld, Jan Daerr, Achim Lother, Caroline Geisen, Lutz Hein, Satoru Takahashi, Guang Li, Wilhelm Röll, Wilhelm Bloch, Peter F. M. van der Ven, Wolfgang A. Linke, Sean M. Wu, Pitter F. Huesgen, Jörg Höhfeld, Dieter O. Fürst, Bernd K. Fleischmann, Michael Hesse

Nat Commun. 2021; 12: 3575. Published online 2021 Jun 11. doi: 10.1038/s41467-021-23858-7

PMCID:: PMC8196106

Abstract Article PDF–8.4M

Select item 813455117.

Cardiomyocyte contractile impairment in heart failure results from reduced BAG3-mediated sarcomeric protein turnover

Thomas G. Martin, Valerie D. Myers, Praveen Dubey, Shubham Dubey, Edith Perez, Christine S. Moravec, Monte S. Willis, Arthur M. Feldman, Jonathan A. Kirk

Nat Commun. 2021; 12: 2942. Published online 2021 May 19. doi: 10.1038/s41467-021-23272-z

PMCID:: PMC8134551

Abstract Article PDF–7.1M

Select item 797977618.

Myopathy associated LDB3 mutation causes Z-disc disassembly and protein aggregation through PKCα and TSC2-mTOR downregulation

Pankaj Pathak, Yotam Blech-Hermoni, Kalpana Subedi, Jessica Mpamugo, Charissa Obeng-Nyarko, Rachel Ohman, Ilda Molloy, Malcolm Kates, Jessica Hale, Stacey Stauffer, Shyam K. Sharan, Ami Mankodi

Commun Biol. 2021; 4: 355. Published online 2021 Mar 19. doi: 10.1038/s42003-021-01864-1

PMCID:: PMC7979776

Abstract Article PDF–5.3M

Select item 793877019.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 786624620.

An Adult Mouse Model of Dilated Cardiomyopathy Caused by Inducible Cardiac-Specific Bis Deletion

Hye Hyeon Yun, Soon Young Jung, Bong Woo Park, Ji Seung Ko, Kyunghyun Yoo, Jiyoung Yeo, Hong Lim Kim, Hun Jun Park, Ho Joong Youn, Jeong Hwa Lee

Int J Mol Sci. 2021 Feb; 22(3): 1343. Published online 2021 Jan 29. doi: 10.3390/ijms22031343

PMCID:: PMC7866246

Abstract Article PDF–2.2M

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