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Select item 111221211.

Transcriptomic Insights into Host Metabolism and Immunity Changes after Parasitization by Leptopilina myrica

Junwei Zhang, Jieyu Shan, Wenqi Shi, Ting Feng, Yifeng Sheng, Zixuan Xu, Zhi Dong, Jianhua Huang, Jiani Chen

Insects. 2024 May; 15(5): 352. Published online 2024 May 14. doi: 10.3390/insects15050352

PMCID:: PMC11122121

Abstract Article PDF–2.4M

Select item 109570852.

A single amino acid polymorphism in natural Metchnikowin alleles of Drosophila results in systemic immunity and life history tradeoffs

Jessamyn I. Perlmutter, Joanne R. Chapman, Mason C. Wilkinson, Isaac Nevarez-Saenz, Robert L. Unckless

PLoS Genet. 2024 Mar; 20(3): e1011155. Published online 2024 Mar 11. doi: 10.1371/journal.pgen.1011155

PMCID:: PMC10957085

Abstract Article PDF–1.7M

Select item 109455083.

DNA damage signaling in Drosophila macrophages modulates systemic cytokine levels in response to oxidative stress

Fabian Hersperger, Tim Meyring, Pia Weber, Chintan Chhatbar, Gianni Monaco, Marc S Dionne, Katrin Paeschke, Marco Prinz, Olaf Groß, Anne-Kathrin Classen, Katrin Kierdorf

eLife. 2024; 12: RP86700. Published online 2024 Jan 8. doi: 10.7554/eLife.86700

PMCID:: PMC10945508

Abstract Article PDF–5.7M

Select item 109359544.

Mitochondrial perturbation in immune cells enhances cell-mediated innate immunity in Drosophila

Laura Vesala, Yuliya Basikhina, Tea Tuomela, Anssi Nurminen, Emilia Siukola, Pedro F. Vale, Tiina S. Salminen

BMC Biol. 2024; 22: 60. Published online 2024 Mar 13. doi: 10.1186/s12915-024-01858-5

PMCID:: PMC10935954

Abstract Article PDF–2.4M

Select item 107871065.

Branched‐Chain Amino Acid Accumulation Fuels the Senescence‐Associated Secretory Phenotype

Yaosi Liang, Christopher Pan, Tao Yin, Lu Wang, Xia Gao, Ergang Wang, Holly Quang, De Huang, Lianmei Tan, Kun Xiang, Yu Wang, Peter B. Alexander, Qi‐Jing Li, Tso‐Pang Yao, Zhao Zhang, Xiao‐Fan Wang

Adv Sci (Weinh) 2024 Jan; 11(2): 2303489. Published online 2023 Nov 15. doi: 10.1002/advs.202303489

PMCID:: PMC10787106

Abstract Article PDF–5.0M

Select item 107773516.

Magnetic Yeast Glucan Particles for Antibody-Free Separation of Viable Macrophages from Drosophila melanogaster

Gabriela Krejčová, Ivan Saloň, Vojtěch Klimša, Pavel Ulbrich, Ayse Beyza Aysan, Adam Bajgar, František Štěpánek

ACS Biomater Sci Eng. 2024 Jan 8; 10(1): 355–364. Published online 2023 Dec 4. doi: 10.1021/acsbiomaterials.3c01199

PMCID:: PMC10777351

Abstract Article PDF–7.3M

Select item 107499477.

Markers and mechanisms of death in Drosophila

John Tower

Front Aging. 2023; 4: 1292040. Published online 2023 Dec 12. doi: 10.3389/fragi.2023.1292040

PMCID:: PMC10749947

Abstract Article PDF–1.4M

Select item 105472118.

Neuronal expression in Drosophila of an evolutionarily conserved metallophosphodiesterase reveals pleiotropic roles in longevity and odorant response

Kriti Gupta, Sveta Chakrabarti, Vishnu Janardan, Nishita Gogia, Sanghita Banerjee, Swarna Srinivas, Deepthi Mahishi, Sandhya S. Visweswariah

PLoS Genet. 2023 Sep; 19(9): e1010962. Published online 2023 Sep 21. doi: 10.1371/journal.pgen.1010962

PMCID:: PMC10547211

Abstract Article PDF–2.9M

Select item 105372669.

Viruses in Laboratory Drosophila and Their Impact on Host Gene Expression

Oumie Kuyateh, Darren J. Obbard

Viruses. 2023 Sep; 15(9): 1849. Published online 2023 Aug 31. doi: 10.3390/v15091849

PMCID:: PMC10537266

Abstract Article PDF–3.5M

Select item 1043400410.

Mycobacterium abscessus Opsonization Allows an Escape from the Defensin Bactericidal Action in Drosophila

Hamadoun Touré, Nicolas Durand, Isabelle Guénal, Jean-Louis Herrmann, Fabienne Girard-Misguich, Sébastien Szuplewski

Microbiol Spectr. 2023 Jul-Aug; 11(4): e00777-23. Published online 2023 Jun 1. doi: 10.1128/spectrum.00777-23

PMCID:: PMC10434004

Abstract Article PDF–1.7M

Select item 1027036011.

Steroid hormone regulation of innate immunity in Drosophila melanogaster

Scott A. Keith

PLoS Genet. 2023 Jun; 19(6): e1010782. Published online 2023 Jun 15. doi: 10.1371/journal.pgen.1010782

PMCID:: PMC10270360

Abstract Article PDF–1.0M

Select item 1026415712.

Downregulation of Hsp90 and the Antimicrobial Peptide Mtk Suppresses Poly(GR)-Induced Neurotoxicity in C9ORF72-ALS/FTD

Soojin Lee, Yong-Woo Jun, Gabriel R. Linares, Brandon Butler, Yeliz Yuva-Adyemir, Jill Moore, Gopinath Krishnan, Bryan Ruiz-Juarez, Manuel Santana, Marine Pons, Neal Silverman, Zhiping Weng, Justin Ichida, Fen-Biao Gao

Neuron. Author manuscript; available in PMC 2024 May 3.

Published in final edited form as: Neuron. 2023 May 3; 111(9): 1381–1390.e6. Published online 2023 Mar 16. doi: 10.1016/j.neuron.2023.02.029

PMCID:: PMC10264157

Abstract Article PDF–1.9M

Select item 1016332413.

Antimicrobial peptides do not directly contribute to aging in Drosophila, but improve lifespan by preventing dysbiosis

Mark A. Hanson, Bruno Lemaitre

Dis Model Mech. 2023 Apr 1; 16(4): dmm049965. Published online 2023 Apr 26. doi: 10.1242/dmm.049965

PMCID:: PMC10163324

Abstract Article

Select item 1007922714.

Mycobacterium abscessus resists the innate cellular response by surviving cell lysis of infected phagocytes

Hamadoun Touré, Lee Ann Galindo, Marion Lagune, Simon Glatigny, Robert M. Waterhouse, Isabelle Guénal, Jean-Louis Herrmann, Fabienne Girard-Misguich, Sébastien Szuplewski

PLoS Pathog. 2023 Mar; 19(3): e1011257. Published online 2023 Mar 27. doi: 10.1371/journal.ppat.1011257

PMCID:: PMC10079227

Abstract Article PDF–2.1M

Select item 1006635215.

Single Cell Analysis of the Fate of Injected Oncogenic RasV12 Cells in Adult Wild Type Drosophila

Di Chen, Xiao Lan, Xiaoming Huang, Jieqing Huang, Xiaojing Zhou, Zhichao Miao, Yuting Ma, Akira Goto, Shanming Ji, Jules A. Hoffmann

J Innate Immun. 2023 Jan-Dec; 15(1): 442–467. Published online 2023 Mar 30. doi: 10.1159/000529096

PMCID:: PMC10066352

Abstract Article PDF–6.1M

Select item 1005994216.

Unraveling the Role of Antimicrobial Peptides in Insects

Sylwia Stączek, Małgorzata Cytryńska, Agnieszka Zdybicka-Barabas

Int J Mol Sci. 2023 Mar; 24(6): 5753. Published online 2023 Mar 17. doi: 10.3390/ijms24065753

PMCID:: PMC10059942

Abstract Article PDF–1.8M

Select item 1005234917.

Adult and Larval Tracheal Systems Exhibit Different Molecular Architectures in Drosophila

Judith Bossen, Ruben Prange, Jan-Philip Kühle, Sven Künzel, Xiao Niu, Jörg U. Hammel, Laura Krieger, Mirjam Knop, Birte Ehrhardt, Karin Uliczka, Susanne Krauss-Etschmann, Thomas Roeder

Int J Mol Sci. 2023 Mar; 24(6): 5628. Published online 2023 Mar 15. doi: 10.3390/ijms24065628

PMCID:: PMC10052349

Abstract Article PDF–5.6M

Select item 1005056118.

Parasitic nematode secreted phospholipase A₂ suppresses cellular and humoral immunity by targeting hemocytes in Drosophila melanogaster

Sophia C. Parks, Ogadinma K. Okakpu, Pakeeza Azizpor, Susan Nguyen, Stephanie Martinez-Beltran, Isaiah Claudio, Kyle Anesko, Anil Bhatia, Harpal S. Dhillon, Adler R. Dillman

Front Immunol. 2023; 14: 1122451. Published online 2023 Mar 15. doi: 10.3389/fimmu.2023.1122451

PMCID:: PMC10050561

Abstract Article PDF–3.6M

Select item 1004112619.

A Toll pathway effector protects Drosophila specifically from distinct toxins secreted by a fungus or a bacterium

Jianqiong Huang, Yanyan Lou, Jiyong Liu, Philippe Bulet, Chuping Cai, Kaiyu Ma, Renjie Jiao, Jules A. Hoffmann, Samuel Liégeois, Zi Li, Dominique Ferrandon

Proc Natl Acad Sci U S A. 2023 Mar 21; 120(12): e2205140120. Published online 2023 Mar 14. doi: 10.1073/pnas.2205140120