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Select item 109359541.

Mitochondrial perturbation in immune cells enhances cell-mediated innate immunity in Drosophila

Laura Vesala, Yuliya Basikhina, Tea Tuomela, Anssi Nurminen, Emilia Siukola, Pedro F. Vale, Tiina S. Salminen

BMC Biol. 2024; 22: 60. Published online 2024 Mar 13. doi: 10.1186/s12915-024-01858-5

PMCID:: PMC10935954

Abstract Article PDF–2.4M

Select item 108162822.

The Lifespan of D. melanogaster Depends on the Function of the Gagr Gene, a Domesticated gag Gene of Drosophila LTR Retrotransposons

Yevgenia Balakireva, Maria Nikitina, Pavel Makhnovskii, Inna Kukushkina, Ilya Kuzmin, Alexander Kim, Lidia Nefedova

Insects. 2024 Jan; 15(1): 68. Published online 2024 Jan 17. doi: 10.3390/insects15010068

PMCID:: PMC10816282

Abstract Article PDF–4.1M

Select item 107325363.

An evolutionarily conserved serine protease network mediates melanization and Toll activation in Drosophila

Tisheng Shan, Yang Wang, Krishna Bhattarai, Haobo Jiang

Sci Adv. 2023 Dec 22; 9(51): eadk2756. Published online 2023 Dec 20. doi: 10.1126/sciadv.adk2756

PMCID:: PMC10732536

Abstract Article PDF–1.3M

Select item 102703514.

Damage sensing mediated by serine proteases Hayan and Persephone for Toll pathway activation in apoptosis-deficient flies

Shotaro Nakano, Soshiro Kashio, Kei Nishimura, Asuka Takeishi, Hina Kosakamoto, Fumiaki Obata, Erina Kuranaga, Takahiro Chihara, Yoshio Yamauchi, Toshiaki Isobe, Masayuki Miura

PLoS Genet. 2023 Jun; 19(6): e1010761. Published online 2023 Jun 15. doi: 10.1371/journal.pgen.1010761

PMCID:: PMC10270351

Abstract Article PDF–2.8M

Select item 100632185.

The Effect of Developmental Pleiotropy on the Evolution of Insect Immune Genes

Alissa M Williams, Thi Minh Ngo, Veronica E Figueroa, Ann T Tate

Genome Biol Evol. 2023 Mar; 15(3): evad044. Published online 2023 Mar 13. doi: 10.1093/gbe/evad044

PMCID:: PMC10063218

Abstract Article PDF–2.1M

Select item 93364666.

Drosophila Innate Immunity Involves Multiple Signaling Pathways and Coordinated Communication Between Different Tissues

Shichao Yu, Fangzhou Luo, Yongyi Xu, Yan Zhang, Li Hua Jin

Front Immunol. 2022; 13: 905370. Published online 2022 Jul 7. doi: 10.3389/fimmu.2022.905370

PMCID:: PMC9336466

Abstract Article PDF–4.4M

Select item 89446667.

Injury-induced inflammatory signaling and hematopoiesis in Drosophila

Cory J. Evans, Ting Liu, Juliet R. Girard, Utpal Banerjee

Proc Natl Acad Sci U S A. 2022 Mar 22; 119(12): e2119109119. Published online 2022 Mar 14. doi: 10.1073/pnas.2119109119

PMCID:: PMC8944666

Abstract Article PDF–2.5M

Select item 87105508.

cGMP signaling pathway that modulates NF-κB activation in innate immune responses

Hirotaka Kanoh, Shinzo Iwashita, Takayuki Kuraishi, Akira Goto, Naoyuki Fuse, Haruna Ueno, Mariko Nimura, Tomohito Oyama, Chang Tang, Ryo Watanabe, Aki Hori, Yoshiki Momiuchi, Hiroki Ishikawa, Hiroaki Suzuki, Kumiko Nabe, Takeshi Takagaki, Masataka Fukuzaki, Li-Li Tong, Sinya Yamada, Yoshiteru Oshima, Toshiro Aigaki, Julian A.T. Dow, Shireen-Anne Davies, Shoichiro Kurata

iScience. 2021 Dec 17; 24(12): 103473. Published online 2021 Nov 18. doi: 10.1016/j.isci.2021.103473

PMCID:: PMC8710550

Abstract Article PDF–2.6M

Select item 81456499.

The Impact of Age on Response to Infection in Drosophila

Noah Sciambra, Stanislava Chtarbanova

Microorganisms. 2021 May; 9(5): 958. Published online 2021 Apr 29. doi: 10.3390/microorganisms9050958

PMCID:: PMC8145649

Abstract Article PDF–797K

Select item 808422910.

Dual proteomics of Drosophila melanogaster hemolymph infected with the heritable endosymbiont Spiroplasma poulsonii

Florent Masson, Samuel Rommelaere, Alice Marra, Fanny Schüpfer, Bruno Lemaitre

PLoS One. 2021; 16(4): e0250524. Published online 2021 Apr 29. doi: 10.1371/journal.pone.0250524

PMCID:: PMC8084229

Abstract Article PDF–1.5M

Select item 761070311.

A SuperFamily-Wide Activity Atlas of Serine Hydrolases in Drosophila Melanogaster

Kundan Kumar, Amol Mhetre, Girish S. Ratnaparkhi, Siddhesh S. Kamat

Biochemistry. Author manuscript; available in PMC 2021 Oct 27.

Published in final edited form as: Biochemistry. 2021 Apr 27; 60(16): 1312–1324. Published online 2021 Apr 7. doi: 10.1021/acs.biochem.1c00171

PMCID:: PMC7610703

Abstract Article PDF–1.7M

Select item 745831212.

Anthrax toxin component, Protective Antigen, protects insects from bacterial infections

Saleem Alameh, Gloria Bartolo, Summer O’Brien, Elizabeth A. Henderson, Leandra O. Gonzalez, Stella Hartmann, Christopher P. Klimko, Jennifer L. Shoe, Christopher K. Cote, Laurence K. Grill, Anastasia Levitin, Mikhail Martchenko Shilman

PLoS Pathog. 2020 Aug; 16(8): e1008836. Published online 2020 Aug 31. doi: 10.1371/journal.ppat.1008836

PMCID:: PMC7458312

Abstract Article PDF–3.8M

Select item 732464213.

Drosophila as a Model Organism in Host–Pathogen Interaction Studies

Salma Younes, Asma Al-Sulaiti, Elham Abdulwahab Ahmed Nasser, Hoda Najjar, Layla Kamareddine

Front Cell Infect Microbiol. 2020; 10: 214. Published online 2020 Jun 23. doi: 10.3389/fcimb.2020.00214

PMCID:: PMC7324642

Abstract Article PDF–1.2M

Select item 713225814.

Iron sequestration by transferrin 1 mediates nutritional immunity in Drosophila melanogaster

Igor Iatsenko, Alice Marra, Jean-Philippe Boquete, Jasquelin Peña, Bruno Lemaitre

Proc Natl Acad Sci U S A. 2020 Mar 31; 117(13): 7317–7325. Published online 2020 Mar 18. doi: 10.1073/pnas.1914830117

PMCID:: PMC7132258

Abstract Article PDF–1.6M

Select item 699908915.

A Receptor Guanylate Cyclase, Gyc76C, Mediates Humoral, and Cellular Responses in Distinct Ways in Drosophila Immunity

Shinzo Iwashita, Hiroaki Suzuki, Akira Goto, Tomohito Oyama, Hirotaka Kanoh, Takayuki Kuraishi, Naoyuki Fuse, Tamaki Yano, Yoshiteru Oshima, Julian A. T. Dow, Shireen-Anne Davies, Shoichiro Kurata

Front Immunol. 2020; 11: 35. Published online 2020 Jan 28. doi: 10.3389/fimmu.2020.00035