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Select item 113418181.

Multiple endocrine defects in adult-onset Sprouty1/2/4 triple knockout mice

Gisela Altés, Anna Olomí, Aida Perramon-Güell, Sara Hernández, Anna Casanovas, Aurora Pérez, Juan Miguel Díaz-Tocados, José Manuel Valdivielso, Cristina Megino, Raúl Navaridas, Xavier Matias-Guiu, Ophir D. Klein, Joaquim Egea, Xavi Dolcet, Andrée Yeramian, Mario Encinas

Sci Rep. 2024; 14: 19479. Published online 2024 Aug 22. doi: 10.1038/s41598-024-70529-w

PMCID:: PMC11341818

Abstract Article PDF–2.8M

Select item 110146572.

A BMP-controlled metabolic/epigenetic signaling cascade directs midfacial morphogenesis

Jingwen Yang, Lingxin Zhu, Haichun Pan, Hiroki Ueharu, Masako Toda, Qian Yang, Shawn A. Hallett, Lorin E. Olson, Yuji Mishina

J Clin Invest. 2024 Apr 15; 134(8): e165787. Published online 2024 Mar 11. doi: 10.1172/JCI165787

PMCID:: PMC11014657

Abstract Article PDF–16M

Select item 108865303.

Conditional Ablation of Spred1 and Spred2 in the Eye Lens Negatively Impacts Its Development and Growth

Fatima Wazin, Frank J. Lovicu

Cells. 2024 Feb; 13(4): 290. Published online 2024 Feb 6. doi: 10.3390/cells13040290

PMCID:: PMC10886530

Abstract Article PDF–14M

Select item 102363084.

Transcription factor Dmrt1 triggers the SPRY1-NF-κB pathway to maintain testicular immune homeostasis and male fertility

Meng-Fei Zhang, Shi-Cheng Wan, Wen-Bo Chen, Dong-Hui Yang, Wen-Qing Liu, Ba-Lun Li, Aili Aierken, Xiao-Min Du, Yun-Xiang Li, Wen-Ping Wu, Xin-Chun Yang, Yu-Dong Wei, Na Li, Sha Peng, Xue-Ling Li, Guang-Peng Li, Jin-Lian Hua

Zool Res. 2023 May 18; 44(3): 505–521. doi: 10.24272/j.issn.2095-8137.2022.440

PMCID:: PMC10236308

Abstract Article PDF–7.8M

Select item 102253535.

Sprouty1 has a protective role in atherogenesis and modifies the migratory and inflammatory phenotype of vascular smooth muscle cells

Xuehui Yang, Chenhao Yang, Robert E. Friesel, Lucy Liaw

Atherosclerosis. Author manuscript; available in PMC 2024 May 1.

Published in final edited form as: Atherosclerosis. 2023 May; 373: 17–28. Published online 2023 Apr 22. doi: 10.1016/j.atherosclerosis.2023.04.007

PMCID:: PMC10225353

Abstract Article PDF–2.6M

Select item 94707066.

A dominant negative mutation uncovers cooperative control of caudal Wolffian duct development by Sprouty genes

Gisela Altés, Marta Vaquero, Sara Cuesta, Carlos Anerillas, Anna Macià, Carme Espinet, Joan Ribera, Saverio Bellusci, Ophir D. Klein, Andree Yeramian, Xavi Dolcet, Joaquim Egea, Mario Encinas

Cell Mol Life Sci. 2022; 79(10): 514. Published online 2022 Sep 13. doi: 10.1007/s00018-022-04546-1

PMCID:: PMC9470706

Abstract Article PDF–4.6M

Select item 89950877.

FOXO1 represses sprouty 2 and sprouty 4 expression to promote arterial specification and vascular remodeling in the mouse yolk sac

Nanbing Li-Villarreal, Rebecca Lee Yean Wong, Monica D. Garcia, Ryan S. Udan, Ross A. Poché, Tara L. Rasmussen, Alexander M. Rhyner, Joshua D. Wythe, Mary E. Dickinson

Development. 2022 Apr 1; 149(7): dev200131. Published online 2022 Apr 1. doi: 10.1242/dev.200131

PMCID:: PMC8995087

Abstract Article

Select item 86173118.

MEK-inhibitor-mediated rescue of skeletal myopathy caused by activating Hras mutation in a Costello syndrome mouse model

William E. Tidyman, Alice F. Goodwin, Yoshiko Maeda, Ophir D. Klein, Katherine A. Rauen

Dis Model Mech. 2022 Feb 1; 15(2): dmm049166. Published online 2021 Nov 19. doi: 10.1242/dmm.049166

PMCID:: PMC8617311

Abstract Article

Select item 85658269.

Sprouty1 regulates gonadal white adipose tissue growth through a PDGFRα/β-Akt pathway

Xuehui Yang, Shivangi Pande, Robert A. Koza, Robert Friesel

Adipocyte. 2021; 10(1): 574–586. Published online 2021 Oct 29. doi: 10.1080/21623945.2021.1987634

PMCID:: PMC8565826

Abstract Article PDF–4.0M

Select item 835889310.

METTL3/N6‐methyladenosine/ miR‐21‐5p promotes obstructive renal fibrosis by regulating inflammation through SPRY1/ERK/NF‐κB pathway activation

Erpeng Liu, Lei Lv, Yonghao Zhan, Yuan Ma, Jinjin Feng, Yulin He, Yibo Wen, Yanping Zhang, Qingsong Pu, Fengping Ji, Xinghuan Yang, Jian Guo Wen

J Cell Mol Med. 2021 Aug; 25(16): 7660–7674. Published online 2021 Jun 24. doi: 10.1111/jcmm.16603

PMCID:: PMC8358893

Abstract Article PDF–3.2M

Select item 820664011.

Loss of Wiz Function Affects Methylation Pattern in Palate Development and Leads to Cleft Palate

Ivana Bukova, Katarzyna Izabela Szczerkowska, Michaela Prochazkova, Inken M. Beck, Jan Prochazka, Radislav Sedlacek

Front Cell Dev Biol. 2021; 9: 620692. Published online 2021 Jun 2. doi: 10.3389/fcell.2021.620692

PMCID:: PMC8206640

Abstract Article PDF–4.5M

Select item 781571212.

Dissection of the Fgf8 regulatory landscape by in vivo CRISPR-editing reveals extensive intra- and inter-enhancer redundancy

A. Hörnblad, S. Bastide, K. Langenfeld, F. Langa, F. Spitz

Nat Commun. 2021; 12: 439. Published online 2021 Jan 19. doi: 10.1038/s41467-020-20714-y

PMCID:: PMC7815712

Abstract Article PDF–3.4M

Select item 760895813.

Nephron Progenitor Maintenance Is Controlled through Fibroblast Growth Factors and Sprouty1 Interaction

Sung-Ho Huh, Ligyeom Ha, Hee-Seong Jang

J Am Soc Nephrol. 2020 Nov; 31(11): 2559–2572. Published online 2020 Aug 4. doi: 10.1681/ASN.2020040401

PMCID:: PMC7608958

Abstract Article

Select item 757505614.

Analysis of FGF20-regulated genes in organ of Corti progenitors by translating ribosome affinity purification

Lu M. Yang, Lisa Stout, Michael Rauchman, David M. Ornitz

Dev Dyn. Author manuscript; available in PMC 2021 Oct 1.

Published in final edited form as: Dev Dyn. 2020 Oct; 249(10): 1217–1242. Published online 2020 Jul 10. doi: 10.1002/dvdy.211

PMCID:: PMC7575056

Abstract Article PDF–4.1M

Select item 719578915.

MiR-21-5p regulates extracellular matrix degradation and angiogenesis in TMJOA by targeting Spry1

Shixing Ma, Aobo Zhang, Xiaole Li, Shizhou Zhang, Shaopeng Liu, Haoming Zhao, Shichao Wu, Lei Chen, Chuan Ma, Huaqiang Zhao

Arthritis Res Ther. 2020; 22: 99. Published online 2020 May 1. doi: 10.1186/s13075-020-2145-y

PMCID:: PMC7195789

Abstract Article PDF–13M

Select item 668370916.

Sprouty1 Controls Genitourinary Development via its N-Terminal Tyrosine

Marta Vaquero, Sara Cuesta, Carlos Anerillas, Gisela Altés, Joan Ribera, M. Albert Basson, Jonathan D. Licht, Joaquim Egea, Mario Encinas

J Am Soc Nephrol. 2019 Aug; 30(8): 1398–1411. Published online 2019 Jul 12. doi: 10.1681/ASN.2018111085

PMCID:: PMC6683709

Abstract Article

Select item 667292917.

Fibroblast Growth Factor Receptors Cooperate to Regulate Neural Progenitor Properties in the Developing Midbrain and Hindbrain

Jonna Saarimäki-Vire, Paula Peltopuro, Laura Lahti, Thorsten Naserke, Alexandra A. Blak, Daniela M. Vogt Weisenhorn, Kai Yu, David M. Ornitz, Wolfgang Wurst, Juha Partanen

J Neurosci. 2007 Aug 8; 27(32): 8581–8592. doi: 10.1523/JNEUROSCI.0192-07.2007