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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 105682472.

circ_0000018 downregulation peripherally ameliorates neuroprotection against acute ischemic stroke through the miR‑871/BCL2L11 axis

Min Jiang, Xiao-Bin Wang, Shan Jiang

Mol Med Rep. 2023 Nov; 28(5): 220. Published online 2023 Sep 28. doi: 10.3892/mmr.2023.13107

PMCID:: PMC10568247

Abstract Article PDF–1.3M

Select item 105473003.

Crk and Crkl Are Required in the Endocardial Lineage for Heart Valve Development

Bingruo Wu, Brian Wu, Sonia Benkaci, Lijie Shi, Pengfei Lu, Taeju Park, Bernice E. Morrow, Yidong Wang, Bin Zhou

J Am Heart Assoc. 2023 Sep 19; 12(18): e029683. Published online 2023 Sep 13. doi: 10.1161/JAHA.123.029683

PMCID:: PMC10547300

Abstract Article PDF–41M

Select item 100704194.

MNT suppresses T cell apoptosis via BIM and is critical for T lymphomagenesis

Hai Vu Nguyen, Cassandra J. Vandenberg, Mikara R. Robati, Ashley P. Ng, Suzanne Cory

Cell Death Differ. 2023 Apr; 30(4): 1018–1032. Published online 2023 Feb 8. doi: 10.1038/s41418-023-01119-y

PMCID:: PMC10070419

Abstract Article PDF–3.0M

Select item 99363095.

PRL2 phosphatase enhances oncogenic FLT3 signaling via dephosphorylation of the E3 ubiquitin ligase CBL at tyrosine 371

Hongxia Chen, Yunpeng Bai, Michihiro Kobayashi, Shiyu Xiao, Wenjie Cai, Sergio Barajas, Sisi Chen, Jinmin Miao, Frederick Nguele Meke, Sasidhar Vemula, James P. Ropa, James M. Croop, H. Scott Boswell, Jun Wan, Yuzhi Jia, Huiping Liu, Loretta S. Li, Jessica K. Altman, Elizabeth A. Eklund, Peng Ji, Wei Tong, Hamid Band, Danny T. Huang, Leonidas C. Platanias, Zhong-Yin Zhang, Yan Liu

Blood. 2023 Jan 19; 141(3): 244–259. Published online 2022 Oct 11. doi: 10.1182/blood.2022016580

Correction in:: Blood. 2024 Jan 25; 143(4): 376.

PMCID:: PMC9936309

Abstract Article

Select item 96842336.

Bim Deletion Reduces Functional Deficits Following Ischemic Stroke in Association with Modulation of Apoptosis and Inflammation

Jason A. Glab, Hamsa Puthalakath, Shenpeng R. Zhang, Antony Vinh, Grant R. Drummond, Christopher G. Sobey, T. Michael De Silva, Hyun Ah Kim

Neuromolecular Med. 2022; 24(4): 405–414. Published online 2022 Feb 11. doi: 10.1007/s12017-022-08703-4

PMCID:: PMC9684233

Abstract Article PDF–1.2M

Select item 95008917.

Nova1 or Bim Deficiency in Pancreatic β-Cells Does Not Alter Multiple Low-Dose Streptozotocin-Induced Diabetes and Diet-Induced Obesity in Mice

Manoja K. Brahma, Peng Xiao, Madalina Popa, Javier Negueruela, Valerie Vandenbempt, Stéphane Demine, Alessandra K. Cardozo, Esteban N. Gurzov

Nutrients. 2022 Sep; 14(18): 3866. Published online 2022 Sep 18. doi: 10.3390/nu14183866

PMCID:: PMC9500891

Abstract Article PDF–3.7M

Select item 84294728.

TRAF2 regulates T cell immunity by maintaining a Tpl2-ERK survival signaling axis in effector and memory CD8 T cells

Xiaoping Xie, Lele Zhu, Zuliang Jie, Yanchuan Li, Meidi Gu, Xiaofei Zhou, Hui Wang, Jae-Hoon Chang, Chun-Jung Ko, Xuhong Cheng, Shao-Cong Sun

Cell Mol Immunol. 2021 Sep; 18(9): 2262–2274. Published online 2020 Nov 17. doi: 10.1038/s41423-020-00583-7

PMCID:: PMC8429472

Abstract Article PDF–4.3M

Select item 82727189.

Absence of Bim sensitizes mice to experimental Trypanosoma cruzi infection

Marcela Hernández-Torres, Rogério Silva do Nascimento, Monica Cardozo Rebouças, Alexandra Cassado, Kely Catarine Matteucci, Maria Regina D’Império-Lima, José Ronnie C. Vasconcelos, Karina R. Bortoluci, José Maria Alvarez, Gustavo P. Amarante-Mendes

Cell Death Dis. 2021 Jul; 12(7): 692. Published online 2021 Jul 10. doi: 10.1038/s41419-021-03964-6

Correction in:: Cell Death Dis. 2021 Sep; 12(9): 817.

PMCID:: PMC8272718

Abstract Article PDF–1.3M

Select item 826539110.

Loss of BIM in T cells results in BCL-2 family BH3-member compensation but incomplete cell death sensitivity normalization

Lindsey M. Ludwig, Lauren E. Roach, Samuel G. Katz, James L. LaBelle

Apoptosis. Author manuscript; available in PMC 2021 Jul 8.

Published in final edited form as: Apoptosis. 2020 Apr; 25(3-4): 247–260. doi: 10.1007/s10495-020-01593-6

PMCID:: PMC8265391

Abstract Article PDF–1.6M

Select item 805863511.

RORγt limits the amount of the cytokine receptor γc through the prosurvival factor Bcl-x_L in developing thymocytes

Davinna L. Ligons, SuJin Hwang, Adam T. Waickman, Joo-Young Park, Megan A. Luckey, Jung-Hyun Park

Sci Signal. Author manuscript; available in PMC 2021 Apr 21.

Published in final edited form as: Sci Signal. 2018 Aug 28; 11(545): eaam8939. Published online 2018 Aug 28. doi: 10.1126/scisignal.aam8939

PMCID:: PMC8058635

Abstract Article PDF–1.5M

Select item 802943812.

MiR‐124 Regulates Apoptosis and Autophagy Process in MPTP Model of Parkinson's Disease by Targeting to Bim

Huiqing Wang, Yongyi Ye, Zhiyuan Zhu, Liqian Mo, Chunnan Lin, Qifu Wang, Haoyuan Wang, Xin Gong, Xiaozheng He, Guohui Lu, Fengfei Lu, Shizhong Zhang

Brain Pathol. 2016 Mar; 26(2): 167–176. Published online 2015 Jun 11. doi: 10.1111/bpa.12267

PMCID:: PMC8029438

Abstract Article PDF–576K

Select item 802656313.

Robust p53 stabilization is dispensable for its activation and tumor suppressor function

Ning Kon, Michael Churchill, Huan Li, Siddhartha Mukherjee, James J. Manfredi, Wei Gu

Cancer Res. Author manuscript; available in PMC 2021 Aug 15.

Published in final edited form as: Cancer Res. 2021 Feb 15; 81(4): 935–944. Published online 2020 Dec 15. doi: 10.1158/0008-5472.CAN-20-1804

PMCID:: PMC8026563

Abstract Article PDF–1.5M

Select item 773761614.

BCL‐XL exerts a protective role against anemia caused by radiation‐induced kidney damage

Kerstin Brinkmann, Paul Waring, Stefan P Glaser, Verena Wimmer, Denny L Cottle, Ming Shen Tham, Duong Nhu, Lachlan Whitehead, Alex RD Delbridge, Guillaume Lessene, Ian M Smyth, Marco J Herold, Gemma L Kelly, Stephanie Grabow, Andreas Strasser

EMBO J. 2020 Dec 15; 39(24): e105561. Published online 2020 Nov 25. doi: 10.15252/embj.2020105561

PMCID:: PMC7737616

Abstract Article PDF–3.8M

Select item 772839415.

Runx2 is essential for the transdifferentiation of chondrocytes into osteoblasts

Xin Qin, Qing Jiang, Kenichi Nagano, Takeshi Moriishi, Toshihiro Miyazaki, Hisato Komori, Kosei Ito, Klaus von der Mark, Chiharu Sakane, Hitomi Kaneko, Toshihisa Komori

PLoS Genet. 2020 Nov; 16(11): e1009169. Published online 2020 Nov 30. doi: 10.1371/journal.pgen.1009169