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Select item 109858381.

MAP3K1 regulates female reproductive tract development

Eiki Kimura, Maureen Mongan, Bo Xiao, Antonius Christianto, Jingjing Wang, Vinicius S. Carreira, Brad Bolon, Xiang Zhang, Katherine A. Burns, Jacek Biesiada, Mario Medvedovic, Alvaro Puga, Ying Xia

Dis Model Mech. 2024 Mar 1; 17(3): dmm050669. Published online 2024 Mar 28. doi: 10.1242/dmm.050669

PMCID:: PMC10985838

Abstract Article

Select item 109427712.

Origin, specification and differentiation of a rare supporting-like lineage in the developing mouse gonad

Chloé Mayère, Violaine Regard, Aitana Perea-Gomez, Corey Bunce, Yasmine Neirijnck, Cyril Djari, Natividad Bellido-Carreras, Pauline Sararols, Richard Reeves, Simon Greenaway, Michelle Simon, Pam Siggers, Diana Condrea, Françoise Kühne, Ivana Gantar, Furong Tang, Isabelle Stévant, Laura Batti, Norbert B. Ghyselinck, Dagmar Wilhelm, Andy Greenfield, Blanche Capel, Marie-Christine Chaboissier, Serge Nef

Sci Adv. 2022 May; 8(21): eabm0972. Published online 2022 May 25. doi: 10.1126/sciadv.abm0972

PMCID:: PMC10942771

Abstract Article PDF–6.7M

Select item 108767033.

TEA domain transcription factor 1 (TEAD1) induces cardiac fibroblasts cells remodeling through BRD4/Wnt4 pathway

Shuai Song, Xiaokai Zhang, Zihang Huang, Yongchao Zhao, Shuyang Lu, Linqi Zeng, Fengze Cai, Tongyao Wang, Zhiqiang Pei, Xinyu Weng, Wei Luo, Hao Lu, Zilun Wei, Jian Wu, Peng Yu, Li Shen, Xiaochun Zhang, Aijun Sun, Junbo Ge

Signal Transduct Target Ther. 2024; 9: 45. Published online 2024 Feb 19. doi: 10.1038/s41392-023-01732-w

PMCID:: PMC10876703

Abstract Article PDF–6.0M

Select item 108614704.

A common allele increases endometrial Wnt4 expression, with antagonistic implications for pregnancy, reproductive cancers, and endometriosis

Mihaela Pavličev, Caitlin E. McDonough-Goldstein, Andreja Moset Zupan, Lisa Muglia, Yueh-Chiang Hu, Fansheng Kong, Nagendra Monangi, Gülay Dagdas, Nina Zupančič, Jamie Maziarz, Debora Sinner, Ge Zhang, Günter Wagner, Louis Muglia

Nat Commun. 2024; 15: 1152. Published online 2024 Feb 12. doi: 10.1038/s41467-024-45338-4

PMCID:: PMC10861470

Abstract Article PDF–2.8M

Select item 107535875.

Loss of NR5A1 in mouse Sertoli cells after sex determination changes cellular identity and induces cell death by anoikis

Sirine Souali-Crespo, Diana Condrea, Nadège Vernet, Betty Féret, Muriel Klopfenstein, Erwan Grandgirard, Violaine Alunni, Marie Cerciat, Matthieu Jung, Chloé Mayere, Serge Nef, Manuel Mark, Frédéric Chalmel, Norbert B. Ghyselinck

Development. 2023 Dec 15; 150(24): dev201710. Published online 2023 Dec 11. doi: 10.1242/dev.201710

PMCID:: PMC10753587

Abstract Article

Select item 106763606.

Acetyl-CoA is a key molecule for nephron progenitor cell pool maintenance

Fabiola Diniz, Nguyen Yen Nhi Ngo, Mariel Colon-Leyva, Francesca Edgington-Giordano, Sylvia Hilliard, Kevin Zwezdaryk, Jiao Liu, Samir S. El-Dahr, Giovane G. Tortelote

Nat Commun. 2023; 14: 7733. Published online 2023 Nov 25. doi: 10.1038/s41467-023-43513-7

PMCID:: PMC10676360

Abstract Article PDF–12M

Select item 105772787.

Rhox8 homeobox gene ablation leads to rete testis abnormality and male subfertility in mice

Yeongseok Oh, Maho Kasu, Constence J Bottoms, Jenna C Douglas, Nikola Sekulovski, Kanako Hayashi, James A MacLean II

Biol Reprod. 2023 Oct; 109(4): 520–532. Published online 2023 Jul 20. doi: 10.1093/biolre/ioad077

PMCID:: PMC10577278

Abstract Article PDF–1.9M

Select item 105473008.

Crk and Crkl Are Required in the Endocardial Lineage for Heart Valve Development

Bingruo Wu, Brian Wu, Sonia Benkaci, Lijie Shi, Pengfei Lu, Taeju Park, Bernice E. Morrow, Yidong Wang, Bin Zhou

J Am Heart Assoc. 2023 Sep 19; 12(18): e029683. Published online 2023 Sep 13. doi: 10.1161/JAHA.123.029683

PMCID:: PMC10547300

Abstract Article PDF–41M

Select item 105064139.

Smarca4 deficiency induces Pttg1 oncogene upregulation and hyperproliferation of tubular and interstitial cells during kidney development

Jinshu Xu, Xianxiao Zhou, Ting Zhang, Bin Zhang, Pin-Xian Xu

Front Cell Dev Biol. 2023; 11: 1233317. Published online 2023 Sep 4. doi: 10.3389/fcell.2023.1233317

PMCID:: PMC10506413

Abstract Article PDF–7.2M

Select item 1047875410.

CHARGE syndrome-associated CHD7 acts at ISL1-regulated enhancers to modulate second heart field gene expression

Athanasia Stathopoulou, Ping Wang, Charlotte Thellier, Robert G Kelly, Deyou Zheng, Peter J Scambler

Cardiovasc Res. 2023 Aug; 119(11): 2089–2105. Published online 2023 Apr 13. doi: 10.1093/cvr/cvad059

Correction in:: Cardiovasc Res. 2024 Jan; 120(1): 120.

PMCID:: PMC10478754

Abstract Article PDF–21M

Select item 1039049211.

Three-dimensional molecular architecture of mouse organogenesis

Fangfang Qu, Wenjia Li, Jian Xu, Ruifang Zhang, Jincan Ke, Xiaodie Ren, Xiaogao Meng, Lexin Qin, Jingna Zhang, Fangru Lu, Xin Zhou, Xi Luo, Zhen Zhang, Minhan Wang, Guangming Wu, Duanqing Pei, Jiekai Chen, Guizhong Cui, Shengbao Suo, Guangdun Peng

Nat Commun. 2023; 14: 4599. Published online 2023 Jul 31. doi: 10.1038/s41467-023-40155-7

PMCID:: PMC10390492

Abstract Article PDF–13M

Select item 1029215712.

A Wnt-Bmp Feedback Circuit Controls Intertissue Signaling Dynamics in Tooth Organogenesis

Daniel J. O’Connell, Joshua W. K. Ho, Tadanori Mammoto, Annick Turbe-Doan, Joyce T. O’Connell, Psalm S. Haseley, Samuel Koo, Nobuhiro Kamiya, Donald E. Ingber, Peter J. Park, Richard L. Maas

Sci Signal. Author manuscript; available in PMC 2023 Jun 26.

Published in final edited form as: Sci Signal. 2012 Jan 10; 5(206): ra4. Published online 2012 Jan 10. doi: 10.1126/scisignal.2002414

PMCID:: PMC10292157

Abstract Article PDF–1.0M

Select item 1028175113.

SOX7 deficiency causes ventricular septal defects through its effects on endocardial-to-mesenchymal transition and the expression of Wnt4 and Bmp2

Andrés Hernández-García, Katherine E Pendleton, Sangbae Kim, Yumei Li, Bum J Kim, Hitisha P Zaveri, Valerie K Jordan, Aliska M Berry, M Cecilia Ljungberg, Rui Chen, Rainer B Lanz, Daryl A Scott

Hum Mol Genet. 2023 Jul 1; 32(13): 2152–2161. Published online 2023 Mar 31. doi: 10.1093/hmg/ddad050

PMCID:: PMC10281751

Abstract Article PDF–1.6M

Select item 1019393714.

CDYL reinforces male gonadal sex determination through epigenetically repressing Wnt4 transcription in mice

Naoki Okashita, Ryo Maeda, Makoto Tachibana

Proc Natl Acad Sci U S A. 2023 May 16; 120(20): e2221499120. Published online 2023 May 8. doi: 10.1073/pnas.2221499120

PMCID:: PMC10193937

Abstract Article PDF–1.9M

Select item 1013407315.

Graded BMP Signaling Within Intestinal Crypt Architecture Directs Self-organization of the Wnt-secreting Stem Cell Niche

Judith Kraiczy, Neil McCarthy, Ermanno Malagola, Guodong Tie, Shariq Madha, Dario Boffelli, Daniel E. Wagner, Timothy C. Wang, Ramesh A. Shivdasani

Cell Stem Cell. Author manuscript; available in PMC 2024 Apr 6.

Published in final edited form as: Cell Stem Cell. 2023 Apr 6; 30(4): 433–449.e8. doi: 10.1016/j.stem.2023.03.004

PMCID:: PMC10134073

Abstract Article PDF–5.1M

Select item 1011292316.

Loss of WNT4 in the gubernaculum causes unilateral cryptorchidism and fertility defects

Abhishek Seth, Juan C. Bournat, Olga Medina-Martinez, Armando Rivera, Joshua Moore, Hunter Flores, Jill A. Rosenfeld, Liya Hu, Carolina J. Jorgez

Development. 2022 Dec 1; 149(23): dev201093. Published online 2022 Nov 30. doi: 10.1242/dev.201093

PMCID:: PMC10112923

Abstract Article

Select item 999099017.

Functional genomics analysis identifies loss of HNF1B function as a cause of Mayer–Rokitansky–Küster–Hauser syndrome

Ella Thomson, Minh Tran, Gorjana Robevska, Katie Ayers, Jocelyn van der Bergen, Prarthna Gopalakrishnan Bhaskaran, Eric Haan, Silvia Cereghini, Alla Vash-Margita, Miranda Margetts, Alison Hensley, Quan Nguyen, Andrew Sinclair, Peter Koopman, Emanuele Pelosi

Hum Mol Genet. 2023 Mar 15; 32(6): 1032–1047. Published online 2022 Oct 25. doi: 10.1093/hmg/ddac262

PMCID:: PMC9990990

Abstract Article PDF–2.2M

Select item 984574518.

Overactive Wnt5a signaling disrupts hair follicle polarity during mouse skin development

Laura Simonson, Ethan Oldham, Hao Chang

Development. 2022 Nov 15; 149(22): dev200816. Published online 2022 Nov 16. doi: 10.1242/dev.200816

PMCID:: PMC9845745

Abstract Article

Select item 977234619.

SOX17-positive rete testis epithelium is required for Sertoli valve formation and normal spermiogenesis in the male mouse

Aya Uchida, Kenya Imaimatsu, Honoka Suzuki, Xiao Han, Hiroki Ushioda, Mami Uemura, Kasane Imura-Kishi, Ryuji Hiramatsu, Hinako M. Takase, Yoshikazu Hirate, Atsuo Ogura, Masami Kanai-Azuma, Akihiko Kudo, Yoshiakira Kanai

Nat Commun. 2022; 13: 7860. Published online 2022 Dec 21. doi: 10.1038/s41467-022-35465-1

PMCID:: PMC9772346

Abstract Article PDF–15M

Select item 970123720.

Creb5 coordinates synovial joint formation with the genesis of articular cartilage

Cheng-Hai Zhang, Yao Gao, Han-Hwa Hung, Zhu Zhuo, Alan J. Grodzinsky, Andrew B. Lassar

Nat Commun. 2022; 13: 7295. Published online 2022 Nov 26. doi: 10.1038/s41467-022-35010-0

PMCID:: PMC9701237

Abstract Article PDF–10M

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