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Select item 115729701.

tRNA modification enzyme-dependent redox homeostasis regulates synapse formation and memory

Kimberly R. Madhwani, Shanzeh Sayied, Carlson H. Ogata, Caley A. Hogan, Jenna M. Lentini, Moushami Mallik, Jennifer L. Dumouchel, Erik Storkebaum, Dragony Fu, Kate M. O’Connor-Giles

Proc Natl Acad Sci U S A. 2024 Nov 12; 121(46): e2317864121. Published online 2024 Nov 4. doi: 10.1073/pnas.2317864121

PMCID:: PMC11572970

Abstract Article PDF–7.4M

Select item 113919672.

Anti-aging and immunomodulatory role of caffeine in Drosophila larvae

Firzan Nainu, Sartini Sartini, Muhammad A. Bahar, Asbah Asbah, Reski A. Rosa, Mukarram Mudjahid, Muhammad F. As’ad, Nadila P. Latada

Narra J. 2024 Aug; 4(2): e818. Published online 2024 Jun 28. doi: 10.52225/narra.v4i2.818

PMCID:: PMC11391967

Abstract Article PDF–368K

Select item 113450913.

Molecular Mechanisms of Drosophila Hematopoiesis

S. A. Sinenko

Acta Naturae. 2024 Apr-Jun; 16(2): 4–21. doi: 10.32607/actanaturae.27410

PMCID:: PMC11345091

Abstract Article PDF–691K

Select item 112748214.

Pathological Defects in a Drosophila Model of Alzheimer’s Disease and Beneficial Effects of the Natural Product Lisosan G

Silvia Bongiorni, Elisabetta Catalani, Ivan Arisi, Francesca Lazzarini, Simona Del Quondam, Kashi Brunetti, Davide Cervia, Giorgio Prantera

Biomolecules. 2024 Jul; 14(7): 855. Published online 2024 Jul 15. doi: 10.3390/biom14070855

PMCID:: PMC11274821

Abstract Article PDF–2.6M

Select item 112367125.

Drosophila immune cells transport oxygen through PPO2 protein phase transition

Mingyu Shin, Eunji Chang, Daewon Lee, Nayun Kim, Bumsik Cho, Nuri Cha, Ferdinand Koranteng, Ji-Joon Song, Jiwon Shim

Nature. 2024; 631(8020): 350–359. Published online 2024 Jun 26. doi: 10.1038/s41586-024-07583-x

Correction in:: Nature. 2024; 634(8033): E2.

PMCID:: PMC11236712

Abstract Article PDF–14M

Select item 111928396.

Activation of the Keap1/Nrf2 pathway suppresses mitochondrial dysfunction, oxidative stress, and motor phenotypes in C9orf72 ALS/FTD models

Wing Hei Au, Leonor Miller-Fleming, Alvaro Sanchez-Martinez, James AK Lee, Madeleine J Twyning, Hiran A Prag, Laura Raik, Scott P Allen, Pamela J Shaw, Laura Ferraiuolo, Heather Mortiboys, Alexander J Whitworth

Life Sci Alliance. 2024 Sep; 7(9): e202402853. Published online 2024 Jun 21. doi: 10.26508/lsa.202402853

PMCID:: PMC11192839

Abstract Article PDF–3.3M

Select item 111254077.

Curcumin-mediated alleviation of dextran-induced leaky gut in Drosophila melanogaster

Mufliha Khaerani, Rizkya Chaeratunnisa, Annisa Salsabila, Asbah Asbah, Rangga M. Asri, Akiko Shiratsuchi, Firzan Nainu

Narra J. 2024 Apr; 4(1): e743. Published online 2024 Apr 22. doi: 10.52225/narra.v4i1.743

PMCID:: PMC11125407

Abstract Article PDF–704K

Select item 111110758.

Destructive effects of UVC radiation on Drosophila melanogaster: Mortality, fertility, mutations, and molecular mechanisms

Mohamed Lotfy, Aalaa Khattab, Mohammed Shata, Ahmad Alhasbani, Abdulla Almesmari, Saeed Alsaeedi, Saeed Alyassi, Biduth Kundu

PLoS One. 2024; 19(5): e0303115. Published online 2024 May 22. doi: 10.1371/journal.pone.0303115

PMCID:: PMC11111075

Abstract Article PDF–1.3M

Select item 110798759.

Evaluating the Impact of Vitamin D₃ on NF-κB and JAK/STAT Signaling Pathways in Drosophila melanogaster

Widya Hardiyanti, Yulia Yusrini Djabir, Dewita Fatiah, Muhammad Rasul Pratama, Tenri Zulfa Ayu Dwi Putri, Rizkya Chaeratunnisa, Nadila Pratiwi Latada, Mukarram Mudjahid, Rangga Meidianto Asri, Firzan Nainu

ACS Omega. 2024 May 7; 9(18): 20135–20141. Published online 2024 Apr 25. doi: 10.1021/acsomega.4c00134

PMCID:: PMC11079875

Abstract Article PDF–1.8M

Select item 1103542610.

Dietary cysteine and methionine promote peroxisome elevation and fat loss by induction of CG33474 expression in Drosophila adipose tissue

Meng Liu, Li He

Cell Mol Life Sci. 2024 Dec; 81(1): 190. Published online 2024 Apr 22. doi: 10.1007/s00018-024-05226-y

PMCID:: PMC11035426

Abstract Article PDF–5.8M

Select item 1093595411.

Mitochondrial perturbation in immune cells enhances cell-mediated innate immunity in Drosophila

Laura Vesala, Yuliya Basikhina, Tea Tuomela, Anssi Nurminen, Emilia Siukola, Pedro F. Vale, Tiina S. Salminen

BMC Biol. 2024; 22: 60. Published online 2024 Mar 13. doi: 10.1186/s12915-024-01858-5

PMCID:: PMC10935954

Abstract Article PDF–2.4M

Select item 1089197512.

Exposure to the Natural Compound Climacostol Induces Cell Damage and Oxidative Stress in the Fruit Fly Drosophila melanogaster

Elisabetta Catalani, Kashi Brunetti, Simona Del Quondam, Silvia Bongiorni, Simona Picchietti, Anna Maria Fausto, Gabriele Lupidi, Enrico Marcantoni, Cristiana Perrotta, Gabriele Achille, Federico Buonanno, Claudio Ortenzi, Davide Cervia

Toxics. 2024 Feb; 12(2): 102. Published online 2024 Jan 24. doi: 10.3390/toxics12020102

PMCID:: PMC10891975

Abstract Article PDF–6.2M

Select item 1085680913.

Betulinic Acid Increases the Lifespan of Drosophila melanogaster via Sir2 and FoxO Activation

Hye-Yeon Lee, Kyung-Jin Min

Nutrients. 2024 Feb; 16(3): 441. Published online 2024 Feb 1. doi: 10.3390/nu16030441

PMCID:: PMC10856809

Abstract Article PDF–2.3M

Select item 1056344814.

N‐acetyl‐l‐tyrosine is an intrinsic triggering factor of mitohormesis in stressed animals

Takashi Matsumura, Outa Uryu, Fumikazu Matsuhisa, Keiji Tajiri, Hitoshi Matsumoto, Yoichi Hayakawa

EMBO Rep. 2020 May 6; 21(5): e49211. Published online 2020 Mar 2. doi: 10.15252/embr.201949211

PMCID:: PMC10563448

Abstract Article PDF–2.4M

Select item 1055747615.

Isoforms of the transcriptional cofactor SIN3 differentially regulate genes necessary for energy metabolism and cell survival

Anindita Mitra, Linh Vo, Imad Soukar, Ashlesha Chaubal, Miriam L. Greenberg, Lori A. Pile

Biochim Biophys Acta Mol Cell Res. Author manuscript; available in PMC 2023 Oct 6.

Published in final edited form as: Biochim Biophys Acta Mol Cell Res. 2022 Oct; 1869(10): 119322. Published online 2022 Jul 9. doi: 10.1016/j.bbamcr.2022.119322

PMCID:: PMC10557476

Abstract Article PDF–1.9M

Select item 1052644516.

Assessing Curcumin Uptake and Clearance and Their Influence on Superoxide Dismutase Activity in Drosophila melanogaster

Tammy R. Hoffman, Sarah A. Emsley, Jenna C. Douglas, Kaela R. Reed, Abigail R. Esquivel, Marc J. Koyack, Brie E. Paddock, Patrick Videau

BioTech (Basel) 2023 Sep; 12(3): 58. Published online 2023 Sep 8. doi: 10.3390/biotech12030058

PMCID:: PMC10526445

Abstract Article PDF–1.4M

Select item 1047412617.

Nacα protects the larval fat body from cell death by maintaining cellular proteostasis in Drosophila

Takayuki Yamada, Yuto Yoshinari, Masayuki Tobo, Okiko Habara, Takashi Nishimura

Nat Commun. 2023; 14: 5328. Published online 2023 Sep 1. doi: 10.1038/s41467-023-41103-1

PMCID:: PMC10474126

Abstract Article PDF–13M

Select item 1040769918.

5-Aminolevulinic acid bypasses mitochondrial complex I deficiency and corrects physiological dysfunctions in Drosophila

Naoko Nozawa, Marie Noguchi, Kanako Shinno, Taro Saito, Akiko Asada, Takuya Ishii, Kiwamu Takahashi, Masahiro Ishizuka, Kanae Ando

Hum Mol Genet. 2023 Aug 15; 32(16): 2611–2622. Published online 2023 Jun 26. doi: 10.1093/hmg/ddad092

PMCID:: PMC10407699

Abstract Article PDF–1.8M

Select item 1034858819.

Yeast NDI1 reconfigures neuronal metabolism and prevents the unfolded protein response in mitochondrial complex I deficiency

Lucy Granat, Debbra Y. Knorr, Daniel C. Ranson, Emma L. Hamer, Ram Prosad Chakrabarty, Francesca Mattedi, Laura Fort-Aznar, Frank Hirth, Sean T. Sweeney, Alessio Vagnoni, Navdeep S. Chandel, Joseph M. Bateman

PLoS Genet. 2023 Jul; 19(7): e1010793. Published online 2023 Jul 3. doi: 10.1371/journal.pgen.1010793