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Select item 111139821.

Ube3a, the E3 ubiquitin ligase causing Angelman syndrome and linked to autism, regulates protein homeostasis through the proteasomal shuttle Rpn10

So Young Lee, Juanma Ramirez, Maribel Franco, Benoît Lectez, Monika Gonzalez, Rosa Barrio, Ugo Mayor

Cell Mol Life Sci. 2014 Jul; 71(14): 2747–2758. Published online 2013 Dec 1. doi: 10.1007/s00018-013-1526-7

PMCID:: PMC11113982

Abstract Article PDF–1.7M

Select item 109457072.

Comparative interactome analysis of α-arrestin families in human and Drosophila

Kyung-Tae Lee, Inez KA Pranoto, Soon-Young Kim, Hee-Joo Choi, Ngoc Bao To, Hansong Chae, Jeong-Yeon Lee, Jung-Eun Kim, Young V Kwon, Jin-Wu Nam

eLife. 2024; 12: RP88328. Published online 2024 Jan 25. doi: 10.7554/eLife.88328

PMCID:: PMC10945707

Abstract Article PDF–2.8M

Select item 107135733.

The ubiquitin thioesterase YOD1 ameliorates mutant Huntingtin induced pathology in Drosophila

Anita Farkas, Nóra Zsindely, Gábor Nagy, Levente Kovács, Péter Deák, László Bodai

Sci Rep. 2023; 13: 21951. Published online 2023 Dec 11. doi: 10.1038/s41598-023-49241-8

PMCID:: PMC10713573

Abstract Article PDF–2.9M

Select item 104448904.

The deubiquitinase Leon/USP5 interacts with Atg1/ULK1 and antagonizes autophagy

Yueh-Ling Pai, Yuchieh Jay Lin, Wen-Hsin Peng, Li-Ting Huang, He-Yen Chou, Chien-Hsiang Wang, Cheng-Ting Chien, Guang-Chao Chen

Cell Death Dis. 2023 Aug; 14(8): 540. Published online 2023 Aug 22. doi: 10.1038/s41419-023-06062-x

PMCID:: PMC10444890

Abstract Article PDF–4.9M

Select item 103988945.

The E3 ligase Poe promotes Pericentrin degradation

Brian J. Galletta, Ramya Varadarajan, Carey J. Fagerstrom, Bing Yang, Karen Plevock Haase, Katherine McJunkin, Nasser M. Rusan

Mol Biol Cell. 2023 Aug 1; 34(9): br15. Published online 2023 Aug 1. doi: 10.1091/mbc.E22-11-0534

PMCID:: PMC10398894

Abstract Article PDF–4.7M

Select item 101057366.

Next-generation large-scale binary protein interaction network for Drosophila melanogaster

Hong-Wen Tang, Kerstin Spirohn, Yanhui Hu, Tong Hao, István A. Kovács, Yue Gao, Richard Binari, Donghui Yang-Zhou, Kenneth H. Wan, Joel S. Bader, Dawit Balcha, Wenting Bian, Benjamin W. Booth, Atina G. Coté, Steffi de Rouck, Alice Desbuleux, Kah Yong Goh, Dae-Kyum Kim, Jennifer J. Knapp, Wen Xing Lee, Irma Lemmens, Cathleen Li, Mian Li, Roujia Li, Hyobin Julianne Lim, Yifang Liu, Katja Luck, Dylan Markey, Carl Pollis, Sudharshan Rangarajan, Jonathan Rodiger, Sadie Schlabach, Yun Shen, Dayag Sheykhkarimli, Bridget TeeKing, Frederick P. Roth, Jan Tavernier, Michael A. Calderwood, David E. Hill, Susan E. Celniker, Marc Vidal, Norbert Perrimon, Stephanie E. Mohr

Nat Commun. 2023; 14: 2162. Published online 2023 Apr 15. doi: 10.1038/s41467-023-37876-0

PMCID:: PMC10105736

Abstract Article PDF–3.2M

Select item 89900007.

Usp5, Usp34, and Otu1 deubiquitylases mediate DNA repair in Drosophila melanogaster

Zoltán G. Páhi, Levente Kovács, Diána Szűcs, Barbara N. Borsos, Péter Deák, Tibor Pankotai

Sci Rep. 2022; 12: 5870. Published online 2022 Apr 7. doi: 10.1038/s41598-022-09703-x

PMCID:: PMC8990000

Abstract Article PDF–1.5M

Select item 87036578.

Regulation of Hedgehog Signal Transduction by Ubiquitination and Deubiquitination

Qing Zhang, Jin Jiang

Int J Mol Sci. 2021 Dec; 22(24): 13338. Published online 2021 Dec 11. doi: 10.3390/ijms222413338

PMCID:: PMC8703657

Abstract Article PDF–1.5M

Select item 86644869.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 846882710.

Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders

Stefano Sechi, Angela Karimpour-Ghahnavieh, Anna Frappaolo, Laura Di Francesco, Roberto Piergentili, Eugenia Schininà, Pier Paolo D’Avino, Maria Grazia Giansanti

Cells. 2021 Sep; 10(9): 2336. Published online 2021 Sep 6. doi: 10.3390/cells10092336

PMCID:: PMC8468827

Abstract Article PDF–4.1M

Select item 812979311.

Drosophila USP22/nonstop polarizes the actin cytoskeleton during collective border cell migration

Hammed Badmos, Neville Cobbe, Amy Campbell, Richard Jackson, Daimark Bennett

J Cell Biol. 2021 Jul 5; 220(7): e202007005. Published online 2021 May 14. doi: 10.1083/jcb.202007005

PMCID:: PMC8129793

Abstract Article PDF–6.5M

Select item 726148312.

E3 ligase Herc4 regulates Hedgehog signalling through promoting Smoothened degradation

Weirong Jiang, Xia Yao, Zhaoliang Shan, Wenting Li, Yuxue Gao, Qing Zhang

J Mol Cell Biol. 2019 Sep; 11(9): 791–803. Published online 2019 Mar 29. doi: 10.1093/jmcb/mjz024

PMCID:: PMC7261483

Abstract Article PDF–122M

Select item 696157813.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 635187914.

Hyperactivation of Nrf2 increases stress tolerance at the cost of aging acceleration due to metabolic deregulation

Eleni N. Tsakiri, Sentiljana Gumeni, Kalliopi K. Iliaki, Dimitra Benaki, Konstantinos Vougas, Gerasimos P. Sykiotis, Vassilis G. Gorgoulis, Emmanuel Mikros, Luca Scorrano, Ioannis P. Trougakos

Aging Cell. 2019 Feb; 18(1): e12845. Published online 2018 Dec 10. doi: 10.1111/acel.12845

PMCID:: PMC6351879

Abstract Article PDF–3.3M

Select item 626279615.

Prp8 regulates oncogene-induced hyperplastic growth in Drosophila

Cecilia H. Fernández-Espartero, Alberto Rizzo, Alexander D. Fulford, Julia Falo-Sanjuan, Damien Goutte-Gattat, Paulo S. Ribeiro

Development. 2018 Nov 15; 145(22): dev162156. Published online 2018 Nov 12. doi: 10.1242/dev.162156

PMCID:: PMC6262796

Abstract Article

Select item 607860416.

Human R1441C LRRK2 regulates the synaptic vesicle proteome and phosphoproteome in a Drosophila model of Parkinson’s disease

Md Shariful Islam, Hendrik Nolte, Wright Jacob, Anna B. Ziegler, Stefanie Pütz, Yael Grosjean, Karolina Szczepanowska, Aleksandra Trifunovic, Thomas Braun, Hermann Heumann, Rolf Heumann, Bernhard Hovemann, Darren J. Moore, Marcus Krüger

Hum Mol Genet. 2016 Dec 15; 25(24): 5365–5382. Published online 2016 Oct 29. doi: 10.1093/hmg/ddw352

PMCID:: PMC6078604

Abstract Article PDF–1.9M

Select item 590993617.

Self-oligomerization regulates stability of survival motor neuron protein isoforms by sequestering an SCF^Slmb degron

Kelsey M. Gray, Kevin A. Kaifer, David Baillat, Ying Wen, Thomas R. Bonacci, Allison D. Ebert, Amanda C. Raimer, Ashlyn M. Spring, Sara ten Have, Jacqueline J. Glascock, Kushol Gupta, Gregory D. Van Duyne, Michael J. Emanuele, Angus I. Lamond, Eric J. Wagner, Christian L. Lorson, A. Gregory Matera

Mol Biol Cell. 2018 Jan 15; 29(2): 96–110. doi: 10.1091/mbc.E17-11-0627

PMCID:: PMC5909936

Abstract Article PDF–3.1M

Select item 584974018.

Drosophila Ubiquitin C-Terminal Hydrolase Knockdown Model of Parkinson’s Disease

Hiep H. Tran, Suong N. A. Dang, Thanh T. Nguyen, Anh M. Huynh, Linh. M. Dao, Kaeko Kamei, Masamitsu Yamaguchi, Thao T. P. Dang

Sci Rep. 2018; 8: 4468. Published online 2018 Mar 13. doi: 10.1038/s41598-018-22804-w

PMCID:: PMC5849740

Abstract Article PDF–7.5M

Select item 570780519.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 568900220.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

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