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Select item 102131991.

RNAseq analysis of the drug jian-yan-ling (JYL) using both in vivo and in vitro models

Xiaobo Zhang, Yunliang Zhai, Dandan Zhang, Chang Che, Yayun Zhang, Quan Li, Xue Zhang, Lingrui Zhao

Heliyon. 2023 May; 9(5): e16143. Published online 2023 May 19. doi: 10.1016/j.heliyon.2023.e16143

PMCID:: PMC10213199

Abstract Article PDF–5.2M

Select item 101655412.

Systematic analysis of YFP traps reveals common mRNA/protein discordance in neural tissues

Joshua S. Titlow, Maria Kiourlappou, Ana Palanca, Jeffrey Y. Lee, Dalia S. Gala, Darragh Ennis, Joyce J.S. Yu, Florence L. Young, David Miguel Susano Pinto, Sam Garforth, Helena S. Francis, Finn Strivens, Hugh Mulvey, Alex Dallman-Porter, Staci Thornton, Diana Arman, Marissa J. Millard, Aino I. Järvelin, Mary Kay Thompson, Martin Sargent, Ilias Kounatidis, Richard M. Parton, Stephen Taylor, Ilan Davis

J Cell Biol. 2023 Jun 5; 222(6): e202205129. Published online 2023 May 5. doi: 10.1083/jcb.202205129

PMCID:: PMC10165541

Abstract Article PDF–8.4M

Select item 101057363.

Next-generation large-scale binary protein interaction network for Drosophila melanogaster

Hong-Wen Tang, Kerstin Spirohn, Yanhui Hu, Tong Hao, István A. Kovács, Yue Gao, Richard Binari, Donghui Yang-Zhou, Kenneth H. Wan, Joel S. Bader, Dawit Balcha, Wenting Bian, Benjamin W. Booth, Atina G. Coté, Steffi de Rouck, Alice Desbuleux, Kah Yong Goh, Dae-Kyum Kim, Jennifer J. Knapp, Wen Xing Lee, Irma Lemmens, Cathleen Li, Mian Li, Roujia Li, Hyobin Julianne Lim, Yifang Liu, Katja Luck, Dylan Markey, Carl Pollis, Sudharshan Rangarajan, Jonathan Rodiger, Sadie Schlabach, Yun Shen, Dayag Sheykhkarimli, Bridget TeeKing, Frederick P. Roth, Jan Tavernier, Michael A. Calderwood, David E. Hill, Susan E. Celniker, Marc Vidal, Norbert Perrimon, Stephanie E. Mohr

Nat Commun. 2023; 14: 2162. Published online 2023 Apr 15. doi: 10.1038/s41467-023-37876-0

PMCID:: PMC10105736

Abstract Article PDF–3.2M

Select item 99589644.

Functionally Validating Evolutionary Conserved Risk Genes for Parkinson’s Disease in Drosophila melanogaster

Amalie Elton Baisgaard, Kristina Magaard Koldby, Torsten Nygård Kristensen, Mette Nyegaard, Palle Duun Rohde

Insects. 2023 Feb; 14(2): 168. Published online 2023 Feb 9. doi: 10.3390/insects14020168

PMCID:: PMC9958964

Abstract Article PDF–1.1M

Select item 92396805.

An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR-mediated homologous recombination

Oguz Kanca, Jonathan Zirin, Yanhui Hu, Burak Tepe, Debdeep Dutta, Wen-Wen Lin, Liwen Ma, Ming Ge, Zhongyuan Zuo, Lu-Ping Liu, Robert W Levis, Norbert Perrimon, Hugo J Bellen

eLife. 2022; 11: e76077. Published online 2022 Jun 20. doi: 10.7554/eLife.76077

PMCID:: PMC9239680

Abstract Article PDF–1.2M

Select item 86452076.

In vivo proximity biotin ligation identifies the interactome of Egalitarian, a Dynein cargo adaptor

Frederick C. Baker, Hannah Neiswender, Rajalakshmi Veeranan-Karmegam, Graydon B. Gonsalvez

Development. 2021 Nov 15; 148(22): dev199935. Published online 2021 Nov 18. doi: 10.1242/dev.199935

PMCID:: PMC8645207

Abstract Article

Select item 85260017.

Cp1/cathepsin L is required for autolysosomal clearance in Drosophila

Tianqi Xu, Shannon Nicolson, Jarrod J. Sandow, Sonia Dayan, Xin Jiang, Jantina A. Manning, Andrew I. Webb, Sharad Kumar, Donna Denton

Autophagy. 2021; 17(10): 2734–2749. Published online 2020 Oct 28. doi: 10.1080/15548627.2020.1838105

PMCID:: PMC8526001

Abstract Article PDF–12M

Select item 84942288.

A single-cell atlas reveals unanticipated cell type complexity in Drosophila ovaries

Maija Slaidina, Selena Gupta, Torsten U. Banisch, Ruth Lehmann

Genome Res. 2021 Oct; 31(10): 1938–1951. doi: 10.1101/gr.274340.120

PMCID:: PMC8494228

Abstract Article PDF–15M

Select item 84688279.

Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders

Stefano Sechi, Angela Karimpour-Ghahnavieh, Anna Frappaolo, Laura Di Francesco, Roberto Piergentili, Eugenia Schininà, Pier Paolo D’Avino, Maria Grazia Giansanti

Cells. 2021 Sep; 10(9): 2336. Published online 2021 Sep 6. doi: 10.3390/cells10092336

PMCID:: PMC8468827

Abstract Article PDF–4.1M

Select item 824741310.

Harnessing the paradoxical phenotypes of APOE ɛ2 and APOE ɛ4 to identify genetic modifiers in Alzheimer's disease

Young Won Kim, Ismael Al‐Ramahi, Amanda Koire, Stephen J. Wilson, Daniel M. Konecki, Samantha Mota, Shirin Soleimani, Juan Botas, Olivier Lichtarge

Alzheimers Dement. 2021 May; 17(5): 831–846. Published online 2020 Dec 7. doi: 10.1002/alz.12240

PMCID:: PMC8247413

Abstract Article PDF–1.9M

Select item 805234311.

DNase II mediates a parthanatos-like developmental cell death pathway in Drosophila primordial germ cells

Lama Tarayrah-Ibraheim, Elital Chass Maurice, Guy Hadary, Sharon Ben-Hur, Alina Kolpakova, Tslil Braun, Yoav Peleg, Keren Yacobi-Sharon, Eli Arama

Nat Commun. 2021; 12: 2285. Published online 2021 Apr 16. doi: 10.1038/s41467-021-22622-1

PMCID:: PMC8052343

Abstract Article PDF–8.8M

Select item 696157812.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 687804713.

Sex‐dependent and sex‐independent regulatory systems of size variation in natural populations

Hirokazu Okada, Ryohei Yagi, Vincent Gardeux, Bart Deplancke, Ernst Hafen

Mol Syst Biol. 2019 Nov; 15(11): e9012. Published online 2019 Nov 26. doi: 10.15252/msb.20199012

PMCID:: PMC6878047

Abstract Article PDF–2.9M

Select item 650653914.

Tissue-specific (ts)CRISPR as an efficient strategy for in vivo screening in Drosophila

Hagar Meltzer, Efrat Marom, Idan Alyagor, Oded Mayseless, Victoria Berkun, Netta Segal-Gilboa, Tamar Unger, David Luginbuhl, Oren Schuldiner

Nat Commun. 2019; 10: 2113. Published online 2019 May 8. doi: 10.1038/s41467-019-10140-0

PMCID:: PMC6506539

Abstract Article PDF–6.5M

Select item 582397415.

The Circulating Protease Persephone Is an Immune Sensor for Microbial Proteolytic Activities Upstream of the Drosophila Toll Pathway

Najwa Issa, Nina Guillaumot, Emilie Lauret, Nicolas Matt, Christine Schaeffer-Reiss, Alain Van Dorsselaer, Jean-Marc Reichhart, Florian Veillard

Mol Cell. 2018 Feb 15; 69(4): 539–550.e6. doi: 10.1016/j.molcel.2018.01.029

PMCID:: PMC5823974

Abstract Article

Select item 574897416.

Molecular mechanisms of developmentally programmed crinophagy in Drosophila

Tamás Csizmadia, Péter Lőrincz, Krisztina Hegedűs, Szilvia Széplaki, Péter Lőw, Gábor Juhász

J Cell Biol. 2018 Jan 2; 217(1): 361–374. doi: 10.1083/jcb.201702145

PMCID:: PMC5748974

Abstract Article PDF–4.1M

Select item 570780517.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 568900218.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 485564619.

The hnRNP-Htt axis regulates necrotic cell death induced by transcriptional repression through impaired RNA splicing

Y Mao, T Tamura, Y Yuki, D Abe, Y Tamada, S Imoto, H Tanaka, H Homma, K Tagawa, S Miyano, H Okazawa

Cell Death Dis. 2016 Apr; 7(4): e2207. Published online 2016 Apr 28. doi: 10.1038/cddis.2016.101

PMCID:: PMC4855646

Abstract Article PDF–5.5M

Select item 483595820.

Drosophila Mitf regulates the V-ATPase and the lysosomal-autophagic pathway

Valentina Bouché, Alma Perez Espinosa, Luigi Leone, Marco Sardiello, Andrea Ballabio, Juan Botas

Autophagy. 2016 Mar; 12(3): 484–498. Published online 2016 Jan 13. doi: 10.1080/15548627.2015.1134081

PMCID:: PMC4835958

Abstract Article PDF–2.2M

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