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Select item 108764401.

IFT88 maintains sensory function by localising signalling proteins along Drosophila cilia

Sascha Werner, Pilar Okenve-Ramos, Philip Hehlert, Sihem Zitouni, Pranjali Priya, Susana Mendonça, Anje Sporbert, Christian Spalthoff, Martin C Göpfert, Swadhin Chandra Jana, Mónica Bettencourt-Dias

Life Sci Alliance. 2024 May; 7(5): e202302289. Published online 2024 Feb 19. doi: 10.26508/lsa.202302289

PMCID:: PMC10876440

Abstract Article PDF–2.8M

Select item 87105502.

cGMP signaling pathway that modulates NF-κB activation in innate immune responses

Hirotaka Kanoh, Shinzo Iwashita, Takayuki Kuraishi, Akira Goto, Naoyuki Fuse, Haruna Ueno, Mariko Nimura, Tomohito Oyama, Chang Tang, Ryo Watanabe, Aki Hori, Yoshiki Momiuchi, Hiroki Ishikawa, Hiroaki Suzuki, Kumiko Nabe, Takeshi Takagaki, Masataka Fukuzaki, Li-Li Tong, Sinya Yamada, Yoshiteru Oshima, Toshiro Aigaki, Julian A.T. Dow, Shireen-Anne Davies, Shoichiro Kurata

iScience. 2021 Dec 17; 24(12): 103473. Published online 2021 Nov 18. doi: 10.1016/j.isci.2021.103473

PMCID:: PMC8710550

Abstract Article PDF–2.6M

Select item 67297153.

The Drosophila Receptor Guanylyl Cyclase Gyc76C Is Required for Semaphorin-1a-Plexin A-Mediated Axonal Repulsion

Joseph C. Ayoob, Hung-Hsiang Yu, Jonathan R. Terman, Alex L. Kolodkin

J Neurosci. 2004 Jul 28; 24(30): 6639–6649. doi: 10.1523/JNEUROSCI.1104-04.2004

PMCID:: PMC6729715

Abstract Article PDF–997K

Select item 60786044.

Human R1441C LRRK2 regulates the synaptic vesicle proteome and phosphoproteome in a Drosophila model of Parkinson’s disease

Md Shariful Islam, Hendrik Nolte, Wright Jacob, Anna B. Ziegler, Stefanie Pütz, Yael Grosjean, Karolina Szczepanowska, Aleksandra Trifunovic, Thomas Braun, Hermann Heumann, Rolf Heumann, Bernhard Hovemann, Darren J. Moore, Marcus Krüger

Hum Mol Genet. 2016 Dec 15; 25(24): 5365–5382. Published online 2016 Oct 29. doi: 10.1093/hmg/ddw352

PMCID:: PMC6078604

Abstract Article PDF–1.9M

Select item 59313695.

A Whole Animal Platform to Advance A Clinical Kinase Inhibitor Into New Disease Space

Masahiro Sonoshita, Alex P. Scopton, Peter M-U. Ung, Matthew A. Murray, Lisa Silber, Andres Y. Maldonado, Alexander Real, Avner Schlessinger, Ross L. Cagan, Arvin C. Dar

Nat Chem Biol. Author manuscript; available in PMC 2018 Jul 22.

Published in final edited form as: Nat Chem Biol. 2018 Mar; 14(3): 291–298. Published online 2018 Jan 22. doi: 10.1038/nchembio.2556

PMCID:: PMC5931369

Abstract Article PDF–2.9M

Select item 57078056.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 56890027.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 49280478.

Cold acclimation wholly reorganizes the Drosophila melanogaster transcriptome and metabolome

Heath A. MacMillan, Jose M. Knee, Alice B. Dennis, Hiroko Udaka, Katie E. Marshall, Thomas J. S. Merritt, Brent J. Sinclair

Sci Rep. 2016; 6: 28999. Published online 2016 Jun 30. doi: 10.1038/srep28999

PMCID:: PMC4928047

Abstract Article PDF–3.1M

Select item 45327769.

The Hippo pathway promotes cell survival in response to chemical stress

F Di Cara, T M Maile, B D Parsons, A Magico, S Basu, N Tapon, K King-Jones

Cell Death Differ. 2015 Sep; 22(9): 1526–1539. Published online 2015 Mar 13. doi: 10.1038/cdd.2015.10

PMCID:: PMC4532776

Abstract Article PDF–2.5M

Select item 452833010.

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders

Madeline A. Crosby, L. Sian Gramates, Gilberto dos Santos, Beverley B. Matthews, Susan E. St. Pierre, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, David B. Emmert, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1737–1749. Published online 2015 Jun 24. doi: 10.1534/g3.115.018937

PMCID:: PMC4528330

Abstract Article PDF–2.2M

Select item 452832911.

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data

Beverley B. Matthews, Gilberto dos Santos, Madeline A. Crosby, David B. Emmert, Susan E. St. Pierre, L. Sian Gramates, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, Victor Strelets, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1721–1736. Published online 2015 Jun 24. doi: 10.1534/g3.115.018929

PMCID:: PMC4528329

Abstract Article PDF–4.9M

Select item 435288712.

The Release 6 reference sequence of the Drosophila melanogaster genome

Roger A. Hoskins, Joseph W. Carlson, Kenneth H. Wan, Soo Park, Ivonne Mendez, Samuel E. Galle, Benjamin W. Booth, Barret D. Pfeiffer, Reed A. George, Robert Svirskas, Martin Krzywinski, Jacqueline Schein, Maria Carmela Accardo, Elisabetta Damia, Giovanni Messina, María Méndez-Lago, Beatriz de Pablos, Olga V. Demakova, Evgeniya N. Andreyeva, Lidiya V. Boldyreva, Marco Marra, A. Bernardo Carvalho, Patrizio Dimitri, Alfredo Villasante, Igor F. Zhimulev, Gerald M. Rubin, Gary H. Karpen, Susan E. Celniker

Genome Res. 2015 Mar; 25(3): 445–458. doi: 10.1101/gr.185579.114

PMCID:: PMC4352887

Abstract Article PDF–1022K

Select item 432874513.

The RNA-binding protein Arrest (Bruno) regulates alternative splicing to enable myofibril maturation in Drosophila flight muscle

Maria L Spletter, Christiane Barz, Assa Yeroslaviz, Cornelia Schönbauer, Irene R S Ferreira, Mihail Sarov, Daniel Gerlach, Alexander Stark, Bianca H Habermann, Frank Schnorrer

EMBO Rep. 2015 Feb; 16(2): 178–191. Published online 2014 Dec 22. doi: 10.15252/embr.201439791

PMCID:: PMC4328745

Abstract Article PDF–4.8M

Select item 419771014.

Analysis of the expression patterns, subcellular localisations and interaction partners of Drosophila proteins using a pigP protein trap library

Nick Lowe, Johanna S. Rees, John Roote, Ed Ryder, Irina M. Armean, Glynnis Johnson, Emma Drummond, Helen Spriggs, Jenny Drummond, Jose P. Magbanua, Huw Naylor, Bénédicte Sanson, Rebecca Bastock, Sven Huelsmann, Vitor Trovisco, Matthias Landgraf, Seymour Knowles-Barley, J. Douglas Armstrong, Helen White-Cooper, Celia Hansen, Roger G. Phillips, The UK Drosophila Protein Trap Screening Consortium, Kathryn S. Lilley, Steven Russell, Daniel St Johnston

Development. 2014 Oct; 141(20): 3994–4005. doi: 10.1242/dev.111054

PMCID:: PMC4197710

Abstract Article

Select item 386394915.

Phylogenetic Investigation of Peptide Hormone and Growth Factor Receptors in Five Dipteran Genomes

Kevin J. Vogel, Mark R. Brown, Michael R. Strand

Front Endocrinol (Lausanne) 2013; 4: 193. Prepublished online 2013 Nov 25. Published online 2013 Dec 16. doi: 10.3389/fendo.2013.00193

PMCID:: PMC3863949

Abstract Article PDF–4.7M

Select item 353067716.

High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression

Philippe Batut, Alexander Dobin, Charles Plessy, Piero Carninci, Thomas R. Gingeras

Genome Res. 2013 Jan; 23(1): 169–180. doi: 10.1101/gr.139618.112

PMCID:: PMC3530677

Abstract Article PDF–1.5M

Select item 346946717.

The Many Landscapes of Recombination in Drosophila melanogaster

Josep M. Comeron, Ramesh Ratnappan, Samuel Bailin

PLoS Genet. 2012 Oct; 8(10): e1002905. Published online 2012 Oct 11. doi: 10.1371/journal.pgen.1002905

PMCID:: PMC3469467

Abstract Article PDF–1.6M

Select item 310883018.

In Vivo Analysis of Proteomes and Interactomes Using Parallel Affinity Capture (iPAC) Coupled to Mass Spectrometry

Johanna S. Rees, Nick Lowe, Irina M. Armean, John Roote, Glynnis Johnson, Emma Drummond, Helen Spriggs, Edward Ryder, Steven Russell, Daniel St Johnston, Kathryn S. Lilley

Mol Cell Proteomics. 2011 Jun; 10(6): M110.002386. Published online 2011 Mar 29. doi: 10.1074/mcp.M110.002386

PMCID:: PMC3108830

Abstract Article PDF–1.4M

Select item 304044119.

A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionary-conserved pain gene

G. Gregory Neely, Andreas Hess, Michael Costigan, Alex C. Keene, Spyros Goulas, Michiel Langeslag, Robert S Griffin, Inna Belfer, Feng Dai, Shad Smith, Luda Diatchenko, Vaijayanti Gupta, Cui-ping Xia, Sabina Amann, Silke Kreitz, Cornelia Heindl-Erdmann, Susanne Wolz, Cindy V. Ly, Suchir Arora, Rinku Sarangi, Debasis Dan, Maria Novatchkova, Mark Rosenzweig, Dustin Gibson, Darwin Truong, Daniel Schramek, Tamara Zoranovic, Shane J. F. Cronin, Belinda Angjeli, Kay Brune, Georg Dietzl, William Maixner, Arabella Meixner, Winston Thomas, J. Andrew Pospisilik, Mattias Alenius, Michaela Kress, Sai Subramaniam, Paul A. Garrity, Hugo J. Bellen, Clifford J. Woolf, Josef M. Penninger

Cell. Author manuscript; available in PMC 2011 Nov 12.

Published in final edited form as: Cell. 2010 Nov 12; 143(4): 628–638. doi: 10.1016/j.cell.2010.09.047

PMCID:: PMC3040441

Abstract Article PDF–2.0M

Select item 282505320.

Sequence Finishing and Mapping of Drosophila melanogaster Heterochromatin

Roger A. Hoskins, Joseph W. Carlson, Cameron Kennedy, David Acevedo, Martha Evans-Holm, Erwin Frise, Kenneth H. Wan, Soo Park, Maria Mendez-Lago, Fabrizio Rossi, Alfredo Villasante, Patrizio Dimitri, Gary H. Karpen, Susan E. Celniker

Science. Author manuscript; available in PMC 2010 Feb 19.

Published in final edited form as: Science. 2007 Jun 15; 316(5831): 1625–1628. doi: 10.1126/science.1139816

PMCID:: PMC2825053

Abstract Article PDF–858K

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