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Select item 108415441.

Lysine 117 on ataxin-3 modulates toxicity in Drosophila models of Spinocerebellar Ataxia Type 3

Jessica R. Blount, Nikhil C. Patel, Kozeta Libohova, Autumn L. Harris, Wei-Ling Tsou, Alyson Sujkowski, Sokol V. Todi

J Neurol Sci. Author manuscript; available in PMC 2024 Nov 15.

Published in final edited form as: J Neurol Sci. 2023 Nov 15; 454: 120828. Published online 2023 Oct 5. doi: 10.1016/j.jns.2023.120828

PMCID:: PMC10841544

Abstract Article PDF–1.2M

Select item 101057362.

Next-generation large-scale binary protein interaction network for Drosophila melanogaster

Hong-Wen Tang, Kerstin Spirohn, Yanhui Hu, Tong Hao, István A. Kovács, Yue Gao, Richard Binari, Donghui Yang-Zhou, Kenneth H. Wan, Joel S. Bader, Dawit Balcha, Wenting Bian, Benjamin W. Booth, Atina G. Coté, Steffi de Rouck, Alice Desbuleux, Kah Yong Goh, Dae-Kyum Kim, Jennifer J. Knapp, Wen Xing Lee, Irma Lemmens, Cathleen Li, Mian Li, Roujia Li, Hyobin Julianne Lim, Yifang Liu, Katja Luck, Dylan Markey, Carl Pollis, Sudharshan Rangarajan, Jonathan Rodiger, Sadie Schlabach, Yun Shen, Dayag Sheykhkarimli, Bridget TeeKing, Frederick P. Roth, Jan Tavernier, Michael A. Calderwood, David E. Hill, Susan E. Celniker, Marc Vidal, Norbert Perrimon, Stephanie E. Mohr

Nat Commun. 2023; 14: 2162. Published online 2023 Apr 15. doi: 10.1038/s41467-023-37876-0

PMCID:: PMC10105736

Abstract Article PDF–3.2M

Select item 99304363.

Identification of potential pathways and biomarkers linked to progression in ALS

Roland G. Huber, Swapnil Pandey, Deepak Chhangani, Diego E. Rincon‐Limas, Nathan P. Staff, Crystal Jing Jing Yeo

Ann Clin Transl Neurol. 2023 Feb; 10(2): 150–165. Published online 2022 Dec 19. doi: 10.1002/acn3.51697

PMCID:: PMC9930436

Abstract Article PDF–2.5M

Select item 92738684.

Identification of Therapeutic Targets for Amyotrophic Lateral Sclerosis Using PandaOmics – An AI-Enabled Biological Target Discovery Platform

Frank W. Pun, Bonnie Hei Man Liu, Xi Long, Hoi Wing Leung, Geoffrey Ho Duen Leung, Quinlan T. Mewborne, Junli Gao, Anastasia Shneyderman, Ivan V. Ozerov, Ju Wang, Feng Ren, Alexander Aliper, Evelyne Bischof, Evgeny Izumchenko, Xiaoming Guan, Ke Zhang, Bai Lu, Jeffrey D. Rothstein, Merit E. Cudkowicz, Alex Zhavoronkov

Front Aging Neurosci. 2022; 14: 914017. Published online 2022 Jun 28. doi: 10.3389/fnagi.2022.914017

PMCID:: PMC9273868

Abstract Article PDF–3.6M

Select item 86644865.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 84688276.

Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders

Stefano Sechi, Angela Karimpour-Ghahnavieh, Anna Frappaolo, Laura Di Francesco, Roberto Piergentili, Eugenia Schininà, Pier Paolo D’Avino, Maria Grazia Giansanti

Cells. 2021 Sep; 10(9): 2336. Published online 2021 Sep 6. doi: 10.3390/cells10092336

PMCID:: PMC8468827

Abstract Article PDF–4.1M

Select item 81725647.

UBE4B, a microRNA-9 target gene, promotes autophagy-mediated Tau degradation

Manivannan Subramanian, Seung Jae Hyeon, Tanuza Das, Yoon Seok Suh, Yun Kyung Kim, Jeong-Soo Lee, Eun Joo Song, Hoon Ryu, Kweon Yu

Nat Commun. 2021; 12: 3291. Published online 2021 Jun 2. doi: 10.1038/s41467-021-23597-9

Correction in:: Nat Commun. 2021; 12: 4257.

PMCID:: PMC8172564

Abstract Article PDF–4.3M

Select item 72895958.

FoxO suppresses endoplasmic reticulum stress to inhibit growth of Tsc1-deficient tissues under nutrient restriction

Avantika Gupta, Hugo Stocker

eLife. 2020; 9: e53159. Published online 2020 Jun 11. doi: 10.7554/eLife.53159

PMCID:: PMC7289595

Abstract Article PDF–3.5M

Select item 71760959.

Drosophila NUAK functions with Starvin/BAG3 in autophagic protein turnover

David Brooks, Fawwaz Naeem, Marta Stetsiv, Samantha C. Goetting, Simranjot Bawa, Nicole Green, Cheryl Clark, Arash Bashirullah, Erika R. Geisbrecht

PLoS Genet. 2020 Apr; 16(4): e1008700. Published online 2020 Apr 22. doi: 10.1371/journal.pgen.1008700

PMCID:: PMC7176095

Abstract Article PDF–6.9M

Select item 699694310.

CHIP modulates APP‐induced autophagy‐dependent pathological symptoms in Drosophila

Luming Zhuang, Fei Peng, Yuanyuan Huang, Wenzhe Li, Jiuhong Huang, Yunqiang Chu, Pu Ren, Ying Sun, Yan Zhang, Elleen Xue, Xiaowei Guo, Xiafeng Shen, Lei Xue

Aging Cell. 2020 Feb; 19(2): e13070. Published online 2019 Nov 28. doi: 10.1111/acel.13070

PMCID:: PMC6996943

Abstract Article PDF–2.6M

Select item 696157811.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 693289012.

Identification of novel genes associated with longevity in Drosophila melanogaster - a computational approach

Bethany S. Hall, Yvonne A. Barnett, Jonathan J. Crofts, Nadia Chuzhanova

Aging (Albany NY) 2019 Dec 15; 11(23): 11244–11267. Published online 2019 Dec 3. doi: 10.18632/aging.102527

PMCID:: PMC6932890

Abstract Article PDF–1.2M

Select item 650653913.

Tissue-specific (ts)CRISPR as an efficient strategy for in vivo screening in Drosophila

Hagar Meltzer, Efrat Marom, Idan Alyagor, Oded Mayseless, Victoria Berkun, Netta Segal-Gilboa, Tamar Unger, David Luginbuhl, Oren Schuldiner

Nat Commun. 2019; 10: 2113. Published online 2019 May 8. doi: 10.1038/s41467-019-10140-0

PMCID:: PMC6506539

Abstract Article PDF–6.5M

Select item 609569214.

An expanded toolkit for gene tagging based on MiMIC and scarless CRISPR tagging in Drosophila

David Li-Kroeger, Oguz Kanca, Pei-Tseng Lee, Sierra Cowan, Michael T Lee, Manish Jaiswal, Jose Luis Salazar, Yuchun He, Zhongyuan Zuo, Hugo J Bellen

eLife. 2018; 7: e38709. Published online 2018 Aug 9. doi: 10.7554/eLife.38709

PMCID:: PMC6095692

Abstract Article PDF–5.2M

Select item 570780515.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 568900216.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 542957017.

High-content behavioral profiling reveals neuronal genetic network modulating Drosophila larval locomotor program

Boanerges Aleman-Meza, Mario Loeza-Cabrera, Omar Peña-Ramos, Michael Stern, Weiwei Zhong

BMC Genet. 2017; 18: 40. Published online 2017 May 12. doi: 10.1186/s12863-017-0513-7

PMCID:: PMC5429570

Abstract Article PDF–919K

Select item 540638618.

The Ubiquitin Ligase CHIP Integrates Proteostasis and Aging by Regulation of Insulin Receptor Turnover

Riga Tawo, Wojciech Pokrzywa, Éva Kevei, Melek E. Akyuz, Vishnu Balaji, Svenja Adrian, Jörg Höhfeld, Thorsten Hoppe

Cell. 2017 Apr 20; 169(3): 470–482.e13. doi: 10.1016/j.cell.2017.04.003

PMCID:: PMC5406386

Abstract Article

Select item 488965819.

mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster

Gildas Lepennetier, Francesco Catania

G3 (Bethesda) 2016 Jun; 6(6): 1617–1626. Published online 2016 Mar 28. doi: 10.1534/g3.116.029231

PMCID:: PMC4889658

Abstract Article PDF–1.5M

Select item 473800520.

Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes

Sadhna Phanse, Cuihong Wan, Blake Borgeson, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Bezginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, W. Brent Derry, Elisabeth R. Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili

Data Brief. 2016 Mar; 6: 715–721. Published online 2015 Dec 12. doi: 10.1016/j.dib.2015.11.062

PMCID:: PMC4738005

Abstract Article PDF–205K

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