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Items: 1 to 20 of 29

1.
E3 ubiquitin ligase NEDD4L negatively regulates inflammation by promoting ubiquitination of MEKK2
Hui Li, Ning Wang, Yu Jiang, Haofei Wang, Zengfeng Xin, Huazhang An, Hao Pan, Wangqian Ma, Ting Zhang, Xiaojian Wang, Wenlong Lin
EMBO Rep. 2022 Nov; 23(11): e54603. Published online 2022 Sep 26. doi: 10.15252/embr.202254603
PMCID:
PMC9638856
AbstractArticlePDF–4.2M
2.
MiR-20a-5p facilitates cartilage repair in osteoarthritis via suppressing mitogen-activated protein kinase kinase kinase 2
Jiazhi Liu, Guo Tang, Wenjun Liu, Yi Zhou, Cunyi Fan, Wei Zhang
Bioengineered. 2022; 13(5): 13801–13814. Published online 2022 Jun 15. doi: 10.1080/21655979.2022.2084270
PMCID:
PMC9276018
AbstractArticlePDF–3.5M
3.
Comments on ‘MAP3K2-regulated intestinal stromal cells define a distinct stem cell niche’
Ningbo Wu, Hongxiang Sun, Jianmei Tan, Yao Zhang, Bing Su
J Mol Cell Biol. 2021 Jun; 13(6): 458–459. Published online 2021 May 19. doi: 10.1093/jmcb/mjab026
PMCID:
PMC8436688
ArticlePDF–152K
4.
MEKK2 mediates aberrant ERK activation in neurofibromatosis type I
Seoyeon Bok, Dong Yeon Shin, Alisha R. Yallowitz, Mark Eiseman, Michelle Cung, Ren Xu, Na Li, Jun Sun, Alfred L. Williams, John E. Scott, Bing Su, Jae-Hyuck Shim, Matthew B. Greenblatt
Nat Commun. 2020; 11: 5704. Published online 2020 Nov 11. doi: 10.1038/s41467-020-19555-6
PMCID:
PMC7658220
AbstractArticlePDF–3.2M
5.
Upregulation of μ3A Drives Homeostatic Plasticity by Re-Routing AMPAR into the Recycling Endosomal Pathway
Celine C. Steinmetz, Vedakumar Tatavarty, Ken Sugino, Yasuyuki Shima, Anne Joseph, Heather Lin, Michael Rutlin, Mary Lambo, Chris M. Hempel, Benjamin W. Okaty, Suzanne Paradis, Sacha B. Nelson, Gina G. Turrigiano
Cell Rep. Author manuscript; available in PMC 2017 Jan 11.
Published in final edited form as: Cell Rep. 2016 Sep 6; 16(10): 2711–2722. Published online 2016 Aug 25. doi: 10.1016/j.celrep.2016.08.009
PMCID:
PMC5226429
AbstractArticlePDF–2.1M
6.
MEKK2 mediates an alternative β-catenin pathway that promotes bone formation
Matthew Blake Greenblatt, Dong Yeon Shin, Hwanhee Oh, Ki-Young Lee, Bo Zhai, Steven P. Gygi, Sutada Lotinun, Roland Baron, Dou Liu, Bing Su, Laurie H. Glimcher, Jae-Hyuck Shim
Proc Natl Acad Sci U S A. 2016 Mar 1; 113(9): E1226–E1235. Published online 2016 Feb 16. doi: 10.1073/pnas.1600813113
PMCID:
PMC4780654
AbstractArticlePDF–1.7M
7.
MEKK2 Regulates Paxillin Ubiquitylation and Localization in MDA-MB 231 Breast Cancer Cells
Magdalene Ameka, Michael P. Kahle, Mathew Perez-Neut, Saverio Gentile, Ahmed A. Mirza, Bruce D. Cuevas
Biochem J. Author manuscript; available in PMC 2015 Nov 15.
Published in final edited form as: Biochem J. 2014 Nov 15; 464(1): 99–108. doi: 10.1042/BJ20140420
PMCID:
PMC4467534
AbstractArticlePDF–1.8M
8.
SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer
Pawel K. Mazur, Nicolas Reynoird, Purvesh Khatri, Pascal W.T.C. Jansen, Alex Wilkinson, Shichong Liu, Olena Barbash, Glenn S. Van Aller, Michael Huddleston, Dashyant Dhanak, Peter J. Tummino, Ryan G. Kruger, Benjamin Garcia, Atul J. Butte, Michiel Vermeulen, Julien Sage, Or Gozani
Nature. Author manuscript; available in PMC 2014 Dec 12.
Published in final edited form as: Nature. 2014 Jun 12; 510(7504): 283–287. Published online 2014 May 21. doi: 10.1038/nature13320
PMCID:
PMC4122675
AbstractArticlePDF–1.4M
9.
MEKK2 Kinase Association with 14-3-3 Protein Regulates Activation of c-Jun N-terminal Kinase
Adi E. Matitau, Timothy V. Gabor, R. Montgomery Gill, Michael P. Scheid
J Biol Chem. 2013 Sep 27; 288(39): 28293–28302. Published online 2013 Aug 20. doi: 10.1074/jbc.M113.511352
PMCID:
PMC3784737
AbstractArticlePDF–1.6M
10.
MAP kinase kinase kinase-2 (MEKK2) regulates hypertrophic remodeling of the right ventricle in hypoxia-induced pulmonary hypertension
R. Dale Brown, S. Kelly Ambler, Min Li, Timothy M. Sullivan, Lauren N. Henry, Joseph T. Crossno, Jr., Carlin S. Long, Timothy P. Garrington, Kurt R. Stenmark
Am J Physiol Heart Circ Physiol. 2013 Jan 15; 304(2): H269–H281. Published online 2012 Nov 2. doi: 10.1152/ajpheart.00158.2012
PMCID:
PMC3543664
AbstractArticle
11.
A direct HDAC4-MAP kinase crosstalk activates muscle atrophy program
Moon-Chang Choi, Todd J. Cohen, Tomasa Barrientos, Bin Wang, Ming Li, Bryan J. Simmons, Jeong Soo Yang, Gregory A. Cox, Ying-Ming Zhao, Tso-Pang Yao
Mol Cell. Author manuscript; available in PMC 2013 Jul 13.
Published in final edited form as: Mol Cell. 2012 Jul 13; 47(1): 122–132. Published online 2012 May 31. doi: 10.1016/j.molcel.2012.04.025
PMCID:
PMC3398192
AbstractArticlePDF–2.8M
12.
Ubiquitin Ligase Smurf1 Controls Osteoblast Activity and Bone Homeostasis by Targeting MEKK2 for Degradation
Motozo Yamashita, Sai-Xia Ying, Gen-mu Zhang, Cuiling Li, Steven Y. Cheng, Chu-xia Deng, Ying E. Zhang
Cell. Author manuscript; available in PMC 2012 Mar 28.
Published in final edited form as: Cell. 2005 Apr 8; 121(1): 101–113. doi: 10.1016/j.cell.2005.01.035
PMCID:
PMC3314294
AbstractArticlePDF–3.6M
13.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
14.
The kinases MEKK2 and MEKK3 regulate Transforming Growth Factor-β-mediated helper T cell differentiation
Xing Chang, Fang Liu, Xiaofang Wang, Aiping Lin, Hongyu Zhao, Bing Su
Immunity. Author manuscript; available in PMC 2012 Feb 25.
Published in final edited form as: Immunity. 2011 Feb 25; 34(2): 201–212. Published online 2011 Feb 17. doi: 10.1016/j.immuni.2011.01.017
PMCID:
PMC3073014
AbstractArticlePDF–631K
15.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
16.
CHIP-dependent termination of MEKK2 regulates temporal ERK activation required for proper hyperosmotic response
Takeshi Maruyama, Hisae Kadowaki, Noriaki Okamoto, Atsushi Nagai, Isao Naguro, Atsushi Matsuzawa, Hiroshi Shibuya, Keiji Tanaka, Shigeo Murata, Kohsuke Takeda, Hideki Nishitoh, Hidenori Ichijo
EMBO J. 2010 Aug 4; 29(15): 2501–2514. Published online 2010 Jun 29. doi: 10.1038/emboj.2010.141
PMCID:
PMC2928693
AbstractArticlePDF–815K
17.
Mitogen-activated Protein Kinase Kinase Kinase 1 Protects against Nickel-induced Acute Lung Injury
Maureen Mongan, Zongqing Tan, Liang Chen, Zhimin Peng, Maggie Dietsch, Bing Su, George Leikauf, Ying Xia
Toxicol Sci. 2008 Aug; 104(2): 405–411. Published online 2008 May 7. doi: 10.1093/toxsci/kfn089
PMCID:
PMC2734296
AbstractArticlePDF–571K
18.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
AbstractArticlePDF–493K
19.
Noncanonical Function of MEKK2 and MEK5 PB1 Domains for Coordinated Extracellular Signal-Regulated Kinase 5 and c-Jun N-Terminal Kinase Signaling
Kazuhiro Nakamura, Gary L. Johnson
Mol Cell Biol. 2007 Jun; 27(12): 4566–4577. Published online 2007 Apr 23. doi: 10.1128/MCB.00125-07
PMCID:
PMC1900063
AbstractArticlePDF–630K
20.
BGEM: An In Situ Hybridization Database of Gene Expression in the Embryonic and Adult Mouse Nervous System
Susan Magdaleno, Patricia Jensen, Craig L Brumwell, Anna Seal, Karen Lehman, Andrew Asbury, Tony Cheung, Tommie Cornelius, Diana M Batten, Christopher Eden, Shannon M Norland, Dennis S Rice, Nilesh Dosooye, Sundeep Shakya, Perdeep Mehta, Tom Curran
PLoS Biol. 2006 Apr; 4(4): e86. Published online 2006 Mar 28. doi: 10.1371/journal.pbio.0040086
PMCID:
PMC1413568
ArticlePDF–99K

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