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Items: 1 to 20 of 53

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Distinct physiological characteristics and altered glucagon signaling in GHRH knockout mice: Implications for longevity
A. Tate Lasher, Liou Y. Sun
Aging Cell. 2023 Dec; 22(12): e13985. Published online 2023 Sep 4. doi: 10.1111/acel.13985
PMCID:
PMC10726877
AbstractArticlePDF–2.6M
3.
Effects of GHRH Deficiency and GHRH Antagonism on Emotional Disorders in Mice
Lucia Recinella, Maria Loreta Libero, Serena Veschi, Anna Piro, Guya Diletta Marconi, Francesca Diomede, Annalisa Chiavaroli, Giustino Orlando, Claudio Ferrante, Rosalba Florio, Alessia Lamolinara, Renzhi Cai, Wei Sha, Andrew V. Schally, Roberto Salvatori, Luigi Brunetti, Sheila Leone
Cells. 2023 Nov; 12(22): 2615. Published online 2023 Nov 12. doi: 10.3390/cells12222615
PMCID:
PMC10670114
AbstractArticlePDF–2.1M
4.
FOXO Transcription Factors Are Required for Normal Somatotrope Function and Growth
Caitlin E Stallings, Jyoti Kapali, Brian W Evans, Stacey R McGee, Buffy S Ellsworth
Endocrinology. 2022 Feb; 163(2): bqab263. Published online 2021 Dec 31. doi: 10.1210/endocr/bqab263
PMCID:
PMC8782608
AbstractArticle
5.
Agonistic analog of growth hormone–releasing hormone promotes neurofunctional recovery and neural regeneration in ischemic stroke
Yueyang Liu, Jingyu Yang, Xiaohang Che, Jianhua Huang, Xianyang Zhang, Xiaoxiao Fu, Jialing Cai, Yang Yao, Haotian Zhang, Ruiping Cai, Xiaomin Su, Qian Xu, Fu Ren, Renzhi Cai, Andrew V. Schally, Ming-Sheng Zhou
Proc Natl Acad Sci U S A. 2021 Nov 23; 118(47): e2109600118. Published online 2021 Nov 15. doi: 10.1073/pnas.2109600118
PMCID:
PMC8617525
AbstractArticlePDF–2.4M
6.
Satb2 regulates the development of dopaminergic neurons in the arcuate nucleus by Dlx1
Qiong Zhang, Lei Zhang, Ying Huang, Pengcheng Ma, Bingyu Mao, Yu-Qiang Ding, Ning-Ning Song
Cell Death Dis. 2021 Oct; 12(10): 879. Published online 2021 Sep 25. doi: 10.1038/s41419-021-04175-9
PMCID:
PMC8464595
AbstractArticlePDF–5.6M
7.
Functional identity of hypothalamic melanocortin neurons depends on Tbx3
Carmelo Quarta, Alexandre Fisette, Yanjun Xu, Gustav Colldén, Beata Legutko, Yu-Ting Tseng, Alexander Reim, Michael Wierer, Maria C. De Rosa, Valentina Klaus, Rick Rausch, Vidhu V. Thaker, Elisabeth Graf, Tim M. Strom, Anne-Laure Poher, Tim Gruber, Ophélia Le Thuc, Alberto Cebrian-Serrano, Dhiraj Kabra, Luigi Bellocchio, Stephen C. Woods, Gert O. Pflugfelder, Rubén Nogueiras, Lori Zeltser, Ilona C. Grunwald Kadow, Anne Moon, Cristina García-Cáceres, Matthias Mann, Mathias Treier, Claudia A. Doege, Matthias H. Tschöp
Nat Metab. Author manuscript; available in PMC 2021 Jul 20.
Published in final edited form as: Nat Metab. 2019 Feb; 1(2): 222–235. Published online 2019 Jan 28. doi: 10.1038/s42255-018-0028-1
PMCID:
PMC8291379
AbstractArticlePDF–2.4M
8.
ARCGHR Neurons Regulate Muscle Glucose Uptake
Juliana Bezerra Medeiros de Lima, Lucas Kniess Debarba, Alan C. Rupp, Nathan Qi, Chidera Ubah, Manal Khan, Olesya Didyuk, Iven Ayyar, Madelynn Koch, Darleen A. Sandoval, Marianna Sadagurski
Cells. 2021 May; 10(5): 1093. Published online 2021 May 3. doi: 10.3390/cells10051093
PMCID:
PMC8147615
AbstractArticlePDF–3.1M
9.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
10.
The histone H3-lysine 4-methyltransferase Mll4 regulates the development of growth hormone-releasing hormone-producing neurons in the mouse hypothalamus
Christian Huisman, Young A. Kim, Shin Jeon, Bongjin Shin, Jeonghoon Choi, Su Jeong Lim, Sung Min Youn, Younjung Park, Medha K. C., Sangsoo Kim, Soo-Kyung Lee, Seunghee Lee, Jae W. Lee
Nat Commun. 2021; 12: 256. Published online 2021 Jan 11. doi: 10.1038/s41467-020-20511-7
PMCID:
PMC7801453
AbstractArticlePDF–5.6M
11.
ERα Signaling in GHRH/Kiss1 Dual-Phenotype Neurons Plays Sex-Specific Roles in Growth and Puberty
David Garcia-Galiano, Alexandra L. Cara, Zachary Tata, Susan J. Allen, Martin G. Myers, Jr, Ernestina Schipani, Carol F. Elias
J Neurosci. 2020 Dec 2; 40(49): 9455–9466. doi: 10.1523/JNEUROSCI.2069-20.2020
PMCID:
PMC7724138
AbstractArticlePDF–5.3M
12.
Tyrosine Hydroxylase Neurons Regulate Growth Hormone Secretion via Short-Loop Negative Feedback
Frederick Wasinski, João A.B. Pedroso, Willian O. dos Santos, Isadora C. Furigo, David Garcia-Galiano, Carol F. Elias, Edward O. List, John J. Kopchick, Raphael E. Szawka, Jose Donato, Jr
J Neurosci. 2020 May 27; 40(22): 4309–4322. doi: 10.1523/JNEUROSCI.2531-19.2020
PMCID:
PMC7252485
AbstractArticlePDF–5.7M
13.
Transcriptomic and metabolomic profiling of long-lived growth hormone releasing hormone knock-out mice: evidence for altered mitochondrial function and amino acid metabolism
Jessica M. Hoffman, Aliza Poonawalla, Mert Icyuz, William R. Swindell, Landon Wilson, Stephen Barnes, Liou Y. Sun
Aging (Albany NY) 2020 Feb 29; 12(4): 3473–3485. Published online 2020 Feb 23. doi: 10.18632/aging.102822
PMCID:
PMC7066919
AbstractArticlePDF–1.3M
14.
Single cell transcriptome analysis of developing arcuate nucleus neurons uncovers their key developmental regulators
Christian Huisman, Hyeyoung Cho, Olivier Brock, Su Jeong Lim, Sung Min Youn, Younjung Park, Sangsoo Kim, Soo-Kyung Lee, Alessio Delogu, Jae W. Lee
Nat Commun. 2019; 10: 3696. Published online 2019 Aug 16. doi: 10.1038/s41467-019-11667-y
Correction in:
Nat Commun. 2020; 11: 1359.
PMCID:
PMC6697706
AbstractArticlePDF–2.8M
15.
Growth Hormone (GH) Deficient Mice With GHRH Gene Ablation Are Severely Deficient in Vaccine and Immune Responses Against Streptococcus pneumoniae
Khalil Farhat, Gwennaëlle Bodart, Chantal Charlet-Renard, Christophe J. Desmet, Michel Moutschen, Yves Beguin, Frédéric Baron, Pierrette Melin, Pascale Quatresooz, Anne-Simone Parent, Daniel Desmecht, Jean-Claude Sirard, Roberto Salvatori, Henri Martens, Vincent G. Geenen
Front Immunol. 2018; 9: 2175. Published online 2018 Oct 2. doi: 10.3389/fimmu.2018.02175
PMCID:
PMC6176084
AbstractArticlePDF–4.6M
16.
Specific subpopulations of hypothalamic leptin receptor-expressing neurons mediate the effects of early developmental leptin receptor deletion on energy balance
Alan C. Rupp, Margaret B. Allison, Justin C. Jones, Christa M. Patterson, Chelsea L. Faber, Nadejda Bozadjieva, Lora K. Heisler, Randy J. Seeley, David P. Olson, Martin G. Myers, Jr.
Mol Metab. 2018 Aug; 14: 130–138. Published online 2018 Jun 6. doi: 10.1016/j.molmet.2018.06.001
PMCID:
PMC6034096
AbstractArticlePDF–1.9M
17.
The Severe Deficiency of the Somatotrope GH-Releasing Hormone/Growth Hormone/Insulin-Like Growth Factor 1 Axis of Ghrh−/− Mice Is Associated With an Important Splenic Atrophy and Relative B Lymphopenia
Gwennaelle Bodart, Khalil Farhat, Chantal Renard-Charlet, Guillaume Becker, Alain Plenevaux, Roberto Salvatori, Vincent Geenen, Henri Martens
Front Endocrinol (Lausanne) 2018; 9: 296. Published online 2018 Jun 6. doi: 10.3389/fendo.2018.00296
PMCID:
PMC5997896
AbstractArticlePDF–1.6M
18.
Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons
Bora Lee, Janghyun Kim, Taekyeong An, Sangsoo Kim, Esha M. Patel, Jacob Raber, Soo-Kyung Lee, Seunghee Lee, Jae W. Lee
Nat Commun. 2018; 9: 2026. Published online 2018 May 23. doi: 10.1038/s41467-018-04377-4
PMCID:
PMC5966420
AbstractArticlePDF–4.9M
19.
Hypothalamic sonic hedgehog is required for cell specification and proliferation of LHX3/LHX4 pituitary embryonic precursors
Gabriela Carreno, John R. Apps, Emily J. Lodge, Leonidas Panousopoulos, Scott Haston, Jose Mario Gonzalez-Meljem, Heidi Hahn, Cynthia L. Andoniadou, Juan Pedro Martinez-Barbera
Development. 2017 Sep 15; 144(18): 3289–3302. doi: 10.1242/dev.153387
PMCID:
PMC5612255
AbstractArticle
20.
Brown Adipose Tissue Function Is Enhanced in Long-Lived, Male Ames Dwarf Mice
Justin Darcy, Samuel McFadden, Yimin Fang, Joshua A. Huber, Chi Zhang, Liou Y. Sun, Andrzej Bartke
Endocrinology. 2016 Dec; 157(12): 4744–4753. Published online 2016 Oct 14. doi: 10.1210/en.2016-1593
PMCID:
PMC5133358
AbstractArticle

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