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Items: 1 to 20 of 119

1.
Protein translation rate determines neocortical neuron fate
Ekaterina Borisova, Andrew G. Newman, Marta Couce Iglesias, Rike Dannenberg, Theres Schaub, Bo Qin, Alexandra Rusanova, Marisa Brockmann, Janina Koch, Marieatou Daniels, Paul Turko, Olaf Jahn, David R. Kaplan, Marta Rosário, Takao Iwawaki, Christian M. T. Spahn, Christian Rosenmund, David Meierhofer, Matthew L. Kraushar, Victor Tarabykin, Mateusz C. Ambrozkiewicz
Nat Commun. 2024; 15: 4879. Published online 2024 Jun 7. doi: 10.1038/s41467-024-49198-w
PMCID:
PMC11161512
AbstractArticlePDF–17M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
USP14 governs CYP2E1 to promote nonalcoholic fatty liver disease through deubiquitination and stabilization of HSP90AA1
Dongqin Wei, Xin Tian, Longbo Zhu, Han Wang, Chao Sun
Cell Death Dis. 2023 Aug; 14(8): 566. Published online 2023 Aug 26. doi: 10.1038/s41419-023-06091-6
PMCID:
PMC10460448
AbstractArticlePDF–15M
4.
HSP90α is needed for the survival of rod photoreceptors and regulates the expression of rod PDE6 subunits
Daniella Munezero, Hunter Aliff, Ezequiel Salido, Thamaraiselvi Saravanan, Urikhan Sanzhaeva, Tongju Guan, Visvanathan Ramamurthy
J Biol Chem. 2023 Jun; 299(6): 104809. Published online 2023 May 11. doi: 10.1016/j.jbc.2023.104809
PMCID:
PMC10250166
AbstractArticlePDF–5.3M
5.
The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3
Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany
Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527
PMCID:
PMC9603860
AbstractArticlePDF–3.4M
6.
Translational reprogramming in response to accumulating stressors ensures critical threshold levels of Hsp90 for mammalian life
Kaushik Bhattacharya, Samarpan Maiti, Szabolcs Zahoran, Lorenz Weidenauer, Dina Hany, Diana Wider, Lilia Bernasconi, Manfredo Quadroni, Martine Collart, Didier Picard
Nat Commun. 2022; 13: 6271. Published online 2022 Oct 21. doi: 10.1038/s41467-022-33916-3
PMCID:
PMC9587034
AbstractArticlePDF–1.7M
7.
A STUB1 ubiquitin ligase/CHIC2 protein complex negatively regulates the IL-3, IL-5, and GM-CSF cytokine receptor common β chain (CSF2RB) protein stability
Sebastian H.J. Koochaki, Mikołaj Słabicki, Ryan Lumpkin, Charles Zou, Roger Belizaire, Eric S. Fischer, Benjamin L. Ebert
J Biol Chem. 2022 Oct; 298(10): 102484. Published online 2022 Sep 13. doi: 10.1016/j.jbc.2022.102484
PMCID:
PMC9574515
AbstractArticlePDF–1.8M
8.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
9.
Heat Shock Protein (HSP) 90’s Mechanistic Role in Contact Hypersensitivity
Seong-Min Kim, Bradley Studnitzer, Aaron Esser-Kahn
J Immunol. Author manuscript; available in PMC 2023 Jun 15.
Published in final edited form as: J Immunol. 2022 Jun 15; 208(12): 2622–2631. Published online 2022 Jun 8. doi: 10.4049/jimmunol.2101023
PMCID:
PMC9308677
AbstractArticlePDF–1.0M
10.
The long noncoding RNA Synage regulates synapse stability and neuronal function in the cerebellum
Fei Wang, Qianqian Wang, Baowei Liu, Lisheng Mei, Sisi Ma, Shujuan Wang, Ruoyu Wang, Yan Zhang, Chaoshi Niu, Zhiqi Xiong, Yong Zheng, Zhi Zhang, Juan Shi, Xiaoyuan Song
Cell Death Differ. 2021 Sep; 28(9): 2634–2650. Published online 2021 Mar 24. doi: 10.1038/s41418-021-00774-3
PMCID:
PMC8408218
AbstractArticlePDF–7.1M
11.
Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins
Benjamin Lang, Jae-Seong Yang, Mireia Garriga-Canut, Silvia Speroni, Moritz Aschern, Maria Gili, Tobias Hoffmann, Gian Gaetano Tartaglia, Sebastian P Maurer
Nucleic Acids Res. 2021 Jul 9; 49(12): 6702–6721. Published online 2021 Jun 16. doi: 10.1093/nar/gkab490
PMCID:
PMC8266617
AbstractArticlePDF–4.0M
12.
MARK2 phosphorylates eIF2α in response to proteotoxic stress
Yu-Ning Lu, Sarah Kavianpour, Tao Zhang, Xumei Zhang, Dao Nguyen, Ravi Thombre, Lu He, Jiou Wang
PLoS Biol. 2021 Mar; 19(3): e3001096. Published online 2021 Mar 11. doi: 10.1371/journal.pbio.3001096
PMCID:
PMC7951919
AbstractArticlePDF–3.7M
13.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
14.
Autophagy Is Required for Maturation of Surfactant-Containing Lamellar Bodies in the Lung and Swim Bladder
Hideaki Morishita, Yuki Kanda, Takeshi Kaizuka, Haruka Chino, Kazuki Nakao, Yoshimi Miki, Yoshitaka Taketomi, Jun-Lin Guan, Makoto Murakami, Atsu Aiba, Noboru Mizushima
Cell Rep. Author manuscript; available in PMC 2020 Dec 29.
Published in final edited form as: Cell Rep. 2020 Dec 8; 33(10): 108477. doi: 10.1016/j.celrep.2020.108477
PMCID:
PMC7770497
AbstractArticlePDF–1.1M
15.
Low dose Hsp90 inhibitor selectively radiosensitizes HNSCC and Pancreatic xenografts
Ranjit K Mehta, Sanjima Pal, Koushik Kondapi, Merna Sitto, Cuyler Dewar, Theresa Devasia, Matthew J Schipper, Dafydd G Thomas, Venkatesha Basrur, Manjunath P. Pai, Yoshihiro Morishima, Yoichi Osawa, William B Pratt, Theodore S Lawrence, Mukesh K Nyati
Clin Cancer Res. Author manuscript; available in PMC 2021 Apr 1.
Published in final edited form as: Clin Cancer Res. 2020 Oct 1; 26(19): 5246–5257. Published online 2020 Jul 27. doi: 10.1158/1078-0432.CCR-19-3102
PMCID:
PMC7541797
AbstractArticlePDF–1.8M
16.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
17.
Inhibition of HSP90 and activation of HSF1 diminishes macrophage NLRP3 inflammasome activity in alcoholic liver injury
Asmita Choudhury, Daniel Bullock, Arlene Lim, Josepmaria Argemi, Pontus Orning, Egil Lien, Ramon Bataller, Pranoti Mandrekar
Alcohol Clin Exp Res. Author manuscript; available in PMC 2021 Jun 1.
Published in final edited form as: Alcohol Clin Exp Res. 2020 Jun; 44(6): 1300–1311. Published online 2020 May 18. doi: 10.1111/acer.14338
PMCID:
PMC7328660
AbstractArticlePDF–908K
18.
A Genome-Wide Screen in Mice To Identify Cell-Extrinsic Regulators of Pulmonary Metastatic Colonisation
Louise van der Weyden, Agnieszka Swiatkowska, Vivek Iyer, Anneliese O. Speak, David J. Adams
G3 (Bethesda) 2020 Jun; 10(6): 1869–1877. Published online 2020 Apr 3. doi: 10.1534/g3.120.401128
PMCID:
PMC7263671
AbstractArticlePDF–1.0M
19.
Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss
Gayle B. Collin, Navdeep Gogna, Bo Chang, Nattaya Damkham, Jai Pinkney, Lillian F. Hyde, Lisa Stone, Jürgen K. Naggert, Patsy M. Nishina, Mark P. Krebs
Cells. 2020 Apr; 9(4): 931. Published online 2020 Apr 10. doi: 10.3390/cells9040931
PMCID:
PMC7227028
AbstractArticlePDF–5.4M
20.
The molecular chaperone Hsp90α deficiency causes retinal degeneration by disrupting Golgi organization and vesicle transportation in photoreceptors
Yuan Wu, Xiudan Zheng, Yubo Ding, Min Zhou, Zhuang Wei, Tao Liu, Kan Liao
J Mol Cell Biol. 2020 Mar; 12(3): 216–229. Published online 2019 Aug 13. doi: 10.1093/jmcb/mjz048
PMCID:
PMC7181719
AbstractArticlePDF–2.6M

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