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Select item 114023111.

Adaptation of STIM1 structure-function relationships for optogenetic control of calcium signaling

Zirui Zhuang, Yuxin Meng, Yu Xue, Yan Wang, Xiangdong Cheng, Ji Jing

J Biol Chem. 2024 Sep; 300(9): 107636. Published online 2024 Aug 8. doi: 10.1016/j.jbc.2024.107636

PMCID:: PMC11402311

Abstract Article PDF–1.8M

Select item 113735992.

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway

Elena Prosdocimi, Veronica Carpanese, Luca Matteo Todesca, Tatiana Varanita, Magdalena Bachmann, Margherita Festa, Daniele Bonesso, Mireia Perez-Verdaguer, Andrea Carrer, Angelo Velle, Roberta Peruzzo, Silvia Muccioli, Davide Doni, Luigi Leanza, Paola Costantini, Frank Stein, Mandy Rettel, Antonio Felipe, Michael J. Edwards, Erich Gulbins, Laura Cendron, Chiara Romualdi, Vanessa Checchetto, Ildiko Szabo

Sci Adv. 2024 Sep 6; 10(36): eadn9361. Published online 2024 Sep 4. doi: 10.1126/sciadv.adn9361

PMCID:: PMC11373599

Abstract Article PDF–11M

Select item 112099353.

Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability

Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson

Cell. Author manuscript; available in PMC 2024 Oct 26.

Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008

PMCID:: PMC11209935

Abstract Article PDF–3.0M

Select item 111270104.

Essential role of N-terminal SAM regions in STIM1 multimerization and function

Matthias Sallinger, Christina Humer, Hwei Ling Ong, Sasirekha Narayanasamy, Qi Tong Lin, Marc Fahrner, Herwig Grabmayr, Sascha Berlansky, Sean Choi, Tony Schmidt, Lena Maltan, Lara Atzgerstorfer, Martin Niederwieser, Irene Frischauf, Christoph Romanin, Peter B. Stathopulos, Indu Ambudkar, Romana Leitner, Daniel Bonhenry, Rainer Schindl

Proc Natl Acad Sci U S A. 2024 May 21; 121(21): e2318874121. Published online 2024 May 16. doi: 10.1073/pnas.2318874121

PMCID:: PMC11127010

Abstract Article PDF–1.4M

Select item 110988095.

The miR-641-STIM1 and SATB1 axes play important roles in the regulation of the Th17/Treg balance in ITP

Hongkai Zhu, Xueqin Ruan, Kexin Zhao, Wenyong Kuang, Sufang Liu, Wenzhe Yan, Xianming Fu, Zhao Cheng, Ruijuan Li, Hongling Peng

Sci Rep. 2024; 14: 11243. Published online 2024 May 16. doi: 10.1038/s41598-024-61660-9

PMCID:: PMC11098809

Abstract Article PDF–3.7M

Select item 109902776.

ER-export and ARFRP1/AP-1–dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication

Guy J. Pearson, Harriet V. Mears, Malgorzata Broncel, Ambrosius P. Snijders, David L. V. Bauer, Jeremy G. Carlton

Sci Adv. 2024 Apr 5; 10(14): eadl5012. Published online 2024 Apr 3. doi: 10.1126/sciadv.adl5012

PMCID:: PMC10990277

Abstract Article PDF–3.9M

Select item 109544857.

STIM1 translocation to the nucleus protects cells from DNA damage

Irene Sanchez-Lopez, Yolanda Orantos-Aguilera, Eulalia Pozo-Guisado, Alberto Alvarez-Barrientos, Sergio Lilla, Sara Zanivan, Christophe Lachaud, Francisco Javier Martin-Romero

Nucleic Acids Res. 2024 Mar 21; 52(5): 2389–2415. Published online 2024 Jan 15. doi: 10.1093/nar/gkae001

Correction in:: Nucleic Acids Res. 2024 May 22; 52(9): 5420.

PMCID:: PMC10954485

Abstract Article PDF–3.5M

Select item 106415248.

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis

Robert S. Kiss, Jarred Chicoine, Youssef Khalil, Robert Sladek, He Chen, Alessandro Pisaturo, Cyril Martin, Jessica D. Dale, Tegan A. Brudenell, Archith Kamath, Jeffrey Kyei-Boahen, Anouar Hafiane, Girija Daliah, Célia Alecki, Tayah S. Hopes, Martin Heier, Irene A. Aligianis, Jean-Jacques Lebrun, Julie Aspden, Emanuele Paci, Anja Kerksiek, Dieter Lütjohann, Peter Clayton, Jimi C. Wills, Alex von Kriegsheim, Tommy Nilsson, Eamonn Sheridan, Mark T. Handley

J Biol Chem. 2023 Nov; 299(11): 105295. Published online 2023 Sep 28. doi: 10.1016/j.jbc.2023.105295

PMCID:: PMC10641524

Abstract Article PDF–3.8M

Select item 106277869.

ESYT1 tethers the ER to mitochondria and is required for mitochondrial lipid and calcium homeostasis

Alexandre Janer, Jordan L Morris, Michiel Krols, Hana Antonicka, Mari J Aaltonen, Zhen-Yuan Lin, Hanish Anand, Anne-Claude Gingras, Julien Prudent, Eric A Shoubridge

Life Sci Alliance. 2024 Jan; 7(1): e202302335. Published online 2023 Nov 6. doi: 10.26508/lsa.202302335

PMCID:: PMC10627786

Abstract Article PDF–5.2M

Select item 1061746710.

The REEP5/TRAM1 complex binds SARS-CoV-2 NSP3 and promotes virus replication

Jie Li, Qi Gui, Feng-Xia Liang, Joseph Sall, Qingyue Zhang, Yatong Duan, Avantika Dhabaria, Manor Askenazi, Beatrix Ueberheide, Kenneth A. Stapleford, Michele Pagano

J Virol. 2023 Oct; 97(10): e00507-23. Published online 2023 Sep 28. doi: 10.1128/jvi.00507-23

PMCID:: PMC10617467

Abstract Article PDF–3.2M

Select item 1048755511.

Role of STIM1 in the Regulation of Cardiac Energy Substrate Preference

Panpan Liu, Zhuli Yang, Youjun Wang, Aomin Sun

Int J Mol Sci. 2023 Sep; 24(17): 13188. Published online 2023 Aug 25. doi: 10.3390/ijms241713188

PMCID:: PMC10487555

Abstract Article PDF–5.1M

Select item 1040091712.

Molecular dynamics simulations reveal the hidden EF-hand of EF-SAM as a possible key thermal sensor for STIM1 activation by temperature

Andrei Neamtu, Dragomir N. Serban, Greg J. Barritt, Dragos Lucian Isac, Tudor Vasiliu, Aatto Laaksonen, Ionela Lacramioara Serban

J Biol Chem. 2023 Aug; 299(8): 104970. Published online 2023 Jun 27. doi: 10.1016/j.jbc.2023.104970

PMCID:: PMC10400917

Abstract Article PDF–3.6M

Select item 1034596313.

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2–Bispecific Antibody for Combination Cancer Therapy

Amr El Zawily, Frederick S. Vizeacoumar, Renuka Dahiya, Sara L. Banerjee, Kalpana K. Bhanumathy, Hussain Elhasasna, Glinton Hanover, Jessica C. Sharpe, Malkon G. Sanchez, Paul Greidanus, R. Greg Stacey, Kyung-Mee Moon, Ilya Alexandrov, Juha P. Himanen, Dimitar B. Nikolov, Humphrey Fonge, Aaron P. White, Leonard J. Foster, Bingcheng Wang, Behzad M. Toosi, Nicolas Bisson, Tajib A. Mirzabekov, Franco J. Vizeacoumar, Andrew Freywald

Clin Cancer Res. 2023 Jul 14; 29(14): 2686–2701. Published online 2023 Mar 28. doi: 10.1158/1078-0432.CCR-22-2535

PMCID:: PMC10345963

Abstract Article PDF–13M

Select item 1023742214.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1007290615.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 997974316.

Knockdown of Stromal Interaction Molecule 1 (STIM1) Suppresses Acute Myeloblastic Leukemia-M5 Cell Line Survival Through Inhibition of Reactive Oxygen Species Activities

Eman Salem Algariri, Rabiatul Basria S.M.N. Mydin, Emmanuel Jairaj Moses, Simon Imakwu Okekpa, Nur Arzuar Abdul Rahim, Narzah Mohd Yusoff

Turk J Haematol. 2023 Mar; 40(1): 11–17. Published online 2023 Feb 28. doi: 10.4274/tjh.galenos.2022.2022.0246

PMCID:: PMC9979743

Abstract Article PDF–909K

Select item 997294517.

Transferrin Receptor Protein 1 Cooperates with mGluR2 To Mediate the Internalization of Rabies Virus and SARS-CoV-2

Xinxin Wang, Zhiyuan Wen, Huizhen Cao, Jie Luo, Lei Shuai, Chong Wang, Jinying Ge, Xijun Wang, Zhigao Bu, Jinliang Wang

J Virol. 2023 Feb; 97(2): e01611-22. Published online 2023 Feb 13. doi: 10.1128/jvi.01611-22

PMCID:: PMC9972945

Abstract Article PDF–3.0M

Select item 992973718.

Swing‐out opening of stromal interaction molecule 1

Ferdinand Horvath, Sascha Berlansky, Lena Maltan, Herwig Grabmayr, Marc Fahrner, Isabella Derler, Christoph Romanin, Thomas Renger, Heinrich Krobath

Protein Sci. 2023 Mar; 32(3): e4571. Published online 2023 Feb 15. doi: 10.1002/pro.4571

PMCID:: PMC9929737

Abstract Article PDF–2.8M

Select item 989023219.

STIM1 and ORAI1 form a novel cold transduction mechanism in sensory and sympathetic neurons

Tamara J Buijs, Bruno Vilar, Chun‐Hsiang Tan, Peter A McNaughton

EMBO J. 2023 Feb; 42(3): e111348. Published online 2022 Dec 16. doi: 10.15252/embj.2022111348

PMCID:: PMC9890232

Abstract Article PDF–1.5M

Select item 986429320.

The miRNA-185-5p/STIM1 Axis Regulates the Invasiveness of Nasopharyngeal Carcinoma Cell Lines by Modulating EGFR Activation-Stimulated Switch from E- to N-Cadherin

Yue Luo, Jiaxiang Ye, Yayan Deng, Yujuan Huang, Xue Liu, Qian He, Yong Chen, Qiuyun Li, Yan Lin, Rong Liang, Yongqiang Li, Jiazhang Wei, Jinyan Zhang

Molecules. 2023 Jan; 28(2): 818. Published online 2023 Jan 13. doi: 10.3390/molecules28020818

PMCID:: PMC9864293

Abstract Article PDF–4.7M

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