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Select item 112138711.

A fluorescent perilipin 2 knock-in mouse model reveals a high abundance of lipid droplets in the developing and adult brain

Sofia Madsen, Ana C. Delgado, Christelle Cadilhac, Vanille Maillard, Fabrice Battiston, Carla Marie Igelbüscher, Simon De Neck, Elia Magrinelli, Denis Jabaudon, Ludovic Telley, Fiona Doetsch, Marlen Knobloch

Nat Commun. 2024; 15: 5489. Published online 2024 Jun 28. doi: 10.1038/s41467-024-49449-w

PMCID:: PMC11213871

Abstract Article PDF–7.1M

Select item 110884652.

SLC25A28 Overexpression Promotes Adipogenesis by Reducing ATGL

Hua Guan, Lin Xiao, Kaikai Hao, Qiang Zhang, Dongliang Wu, Zhanyi Geng, Bowen Duan, Hui Dai, Ruifen Xu, Xuyang Feng

J Diabetes Res. 2024; 2024: 5511454. Published online 2024 May 4. doi: 10.1155/2024/5511454

PMCID:: PMC11088465

Abstract Article PDF–1.9M

Select item 110211973.

Glucose controls lipolysis through Golgi PtdIns4P-mediated regulation of ATGL

Lianggong Ding, Florian Huwyler, Fen Long, Wu Yang, Jonas Binz, Kendra Wernlé, Matthias Pfister, Manuel Klug, Miroslav Balaz, Barbara Ukropcova, Jozef Ukropec, Chunyan Wu, Tongtong Wang, Min Gao, Pierre-Alain Clavien, Philipp Dutkowski, Mark W. Tibbitt, Christian Wolfrum

Nat Cell Biol. 2024; 26(4): 552–566. Published online 2024 Apr 1. doi: 10.1038/s41556-024-01386-y

PMCID:: PMC11021197

Abstract Article PDF–31M

Select item 108509714.

Renal tubule-specific Atgl deletion links kidney lipid metabolism to glucagon-like peptide 1 and insulin secretion independent of renal inflammation or lipotoxicity

Maria F. Fernandes, Juan J. Aristizabal-Henao, Phillip M. Marvyn, Iman M'Hiri, Meghan A. Wiens, Monica Hoang, Manuel Sebastian, Renato Nachbar, Philippe St-Pierre, Kalsha Diaguarachchige De Silva, Geoffrey A. Wood, Jamie W. Joseph, Christine A. Doucette, André Marette, Ken D. Stark, Robin E. Duncan

Mol Metab. 2024 Mar; 81: 101887. Published online 2024 Jan 26. doi: 10.1016/j.molmet.2024.101887

PMCID:: PMC10850971

Abstract Article PDF–2.5M

Select item 108285865.

Unmasking crucial residues in adipose triglyceride lipase for coactivation with comparative gene identification-58

Natalia Kulminskaya, Carlos Francisco Rodriguez Gamez, Peter Hofer, Ines Kathrin Cerk, Noopur Dubey, Roland Viertlmayr, Theo Sagmeister, Tea Pavkov-Keller, Rudolf Zechner, Monika Oberer

J Lipid Res. 2024 Jan; 65(1): 100491. Published online 2023 Dec 20. doi: 10.1016/j.jlr.2023.100491

Correction in:: J Lipid Res. 2024 Aug; 65(8): 100613.

PMCID:: PMC10828586

Abstract Article PDF–4.1M

Select item 108092236.

Epinephrine inhibits PI3Kα via the Hippo kinases

Ting-Yu Lin, Shakti Ramsamooj, Tiffany Perrier, Katarina Liberatore, Louise Lantier, Neil Vasan, Kannan Karukurichi, Seo-Kyoung Hwang, Edward A. Kesicki, Edward R. Kastenhuber, Thorsten Wiederhold, Tomer M. Yaron, Emily M. Huntsman, Mengmeng Zhu, Yilun Ma, Marcia N. Paddock, Guoan Zhang, Benjamin D. Hopkins, Owen McGuinness, Robert E. Schwartz, Baran A. Ersoy, Lewis C. Cantley, Jared L. Johnson, Marcus D. Goncalves

Cell Rep. Author manuscript; available in PMC 2024 Jan 25.

Published in final edited form as: Cell Rep. 2023 Dec 26; 42(12): 113535. Published online 2023 Dec 4. doi: 10.1016/j.celrep.2023.113535

PMCID:: PMC10809223

Abstract Article PDF–2.3M

Select item 105908667.

Sympathetic overdrive and unrestrained adipose lipolysis drive alcohol-induced hepatic steatosis in rodents

Chunxue Zhou, Henry H. Ruiz, Li Ling, Giulia Maurizi, Kenichi Sakamoto, Claudia G. Liberini, Ling Wang, Adrien Stanley, Hale E. Egritag, Sofia M. Sanz, Claudia Lindtner, Mary A. Butera, Christoph Buettner

Mol Metab. 2023 Dec; 78: 101813. Published online 2023 Sep 29. doi: 10.1016/j.molmet.2023.101813

PMCID:: PMC10590866

Abstract Article PDF–2.5M

Select item 104069768.

PNPLA2 mobilizes retinyl esters from retinosomes and promotes the generation of 11-cis-retinal in the visual cycle

Miwa Hara, Wenjing Wu, Volha V. Malechka, Yusuke Takahashi, Jian-Xing Ma, Gennadiy Moiseyev

Cell Rep. Author manuscript; available in PMC 2023 Oct 23.

Published in final edited form as: Cell Rep. 2023 Feb 28; 42(2): 112091. Published online 2023 Feb 8. doi: 10.1016/j.celrep.2023.112091

PMCID:: PMC10406976

Abstract Article PDF–2.1M

Select item 103986729.

PRMT5 links lipid metabolism to contractile function of skeletal muscles

Kun Ho Kim, Zhihao Jia, Madigan Snyder, Jingjuan Chen, Jiamin Qiu, Stephanie N Oprescu, Xiyue Chen, Sabriya A Syed, Feng Yue, Bruno T Roseguini, Anthony N Imbalzano, Changdeng Hu, Shihuan Kuang

EMBO Rep. 2023 Aug; 24(8): e57306. Published online 2023 Jun 19. doi: 10.15252/embr.202357306

PMCID:: PMC10398672

Abstract Article PDF–4.0M

Select item 1023321010.

Ablation of pigment epithelium-derived factor receptor (PEDF-R/Pnpla2) causes photoreceptor degeneration

Alexandra Bernardo-Colón, Lijin Dong, Mones Abu-Asab, Richard S. Brush, Martin-Paul Agbaga, S. Patricia Becerra

J Lipid Res. 2023 May; 64(5): 100358. Published online 2023 Mar 17. doi: 10.1016/j.jlr.2023.100358

PMCID:: PMC10233210

Abstract Article PDF–3.4M

Select item 987505211.

Lipolysis-derived linoleic acid drives beige fat progenitor cell proliferation

Ichitaro Abe, Yasuo Oguri, Anthony R.P. Verkerke, Lauar B. Monteiro, Carly M. Knuth, Christopher Auger, Yunping Qiu, Gregory P. Westcott, Saverio Cinti, Kosaku Shinoda, Marc G. Jeschke, Shingo Kajimura

Dev Cell. Author manuscript; available in PMC 2023 Jan 25.

Published in final edited form as: Dev Cell. 2022 Dec 5; 57(23): 2623–2637.e8. doi: 10.1016/j.devcel.2022.11.007

PMCID:: PMC9875052

Abstract Article PDF–3.6M

Select item 987119712.

N-end Rule–Mediated Proteasomal Degradation of ATGL Promotes Lipid Storage

Jiesi Xu, Zhenglong Liu, Jianxin Zhang, Siyu Chen, Wei Wang, Xuefan Zhao, Mei Zhen, Xun Huang

Diabetes. 2023 Feb; 72(2): 210–222. Published online 2022 Nov 8. doi: 10.2337/db22-0362

PMCID:: PMC9871197

Abstract Article PDF–67M

Select item 981919713.

Lipid-Laden Lung Mesenchymal Cells Foster Breast Cancer Metastasis via Metabolic Reprogramming of Tumor Cells and Natural Killer Cells

Zheng Gong, Qing Li, Jiayuan Shi, Edison T. Liu, Leonard D. Shultz, Guangwen Ren

Cell Metab. Author manuscript; available in PMC 2023 Dec 6.

Published in final edited form as: Cell Metab. 2022 Dec 6; 34(12): 1960–1976.e9. doi: 10.1016/j.cmet.2022.11.003

PMCID:: PMC9819197

Abstract Article PDF–3.2M

Select item 961883714.

Blocking Lipid Uptake Pathways Does not Prevent Toxicity in Adipose Triglyceride Lipase (ATGL) Deficiency

Jide Oluwadare, Ainara G. Cabodevilla, Ni-Huiping Son, Yunying Hu, Adam E. Mullick, Michael Verano, Jose O. Alemán, Ravichandran Ramasamy, Ira J. Goldberg

J Lipid Res. 2022 Nov; 63(11): 100274. Published online 2022 Sep 15. doi: 10.1016/j.jlr.2022.100274

PMCID:: PMC9618837

Abstract Article PDF–4.7M

Select item 957451515.

A STUB1 ubiquitin ligase/CHIC2 protein complex negatively regulates the IL-3, IL-5, and GM-CSF cytokine receptor common β chain (CSF2RB) protein stability

Sebastian H.J. Koochaki, Mikołaj Słabicki, Ryan Lumpkin, Charles Zou, Roger Belizaire, Eric S. Fischer, Benjamin L. Ebert

J Biol Chem. 2022 Oct; 298(10): 102484. Published online 2022 Sep 13. doi: 10.1016/j.jbc.2022.102484

PMCID:: PMC9574515

Abstract Article PDF–1.8M

Select item 956117716.

Chronic intake of high dietary sucrose induces sexually dimorphic metabolic adaptations in mouse liver and adipose tissue

Erin J. Stephenson, Amanda S. Stayton, Aarti Sethuraman, Prahlad K. Rao, Alice Meyer, Charles Klazer Gomes, Molly C. Mulcahy, Liam McAllan, Michelle A. Puchowicz, Joseph F. Pierre, Dave Bridges, Joan C. Han

Nat Commun. 2022; 13: 6062. Published online 2022 Oct 13. doi: 10.1038/s41467-022-33840-6

PMCID:: PMC9561177

Abstract Article PDF–4.8M

Select item 938646417.

The conserved Mediator subunit cyclin C (CCNC) is required for brown adipocyte development and lipid accumulation

Ziyi Song, Alus M. Xiaoli, Youlei Li, Gerile Siqin, Tian Wu, Randy Strich, Jeffrey E. Pessin, Fajun Yang

Mol Metab. 2022 Oct; 64: 101548. Published online 2022 Jul 19. doi: 10.1016/j.molmet.2022.101548

PMCID:: PMC9386464

Abstract Article PDF–6.6M

Select item 927321718.

Lipolysis of bone marrow adipocytes is required to fuel bone and the marrow niche during energy deficits

Ziru Li, Emily Bowers, Junxiong Zhu, Hui Yu, Julie Hardij, Devika P Bagchi, Hiroyuki Mori, Kenneth T Lewis, Katrina Granger, Rebecca L Schill, Steven M Romanelli, Simin Abrishami, Kurt D Hankenson, Kanakadurga Singer, Clifford J Rosen, Ormond A MacDougald

eLife. 2022; 11: e78496. Published online 2022 Jun 22. doi: 10.7554/eLife.78496

PMCID:: PMC9273217

Abstract Article PDF–7.8M

Select item 924285419.

ATGL is a biosynthetic enzyme for fatty acid esters of hydroxy fatty acids

Rucha Patel, Anna Santoro, Peter Hofer, Dan Tan, Monika Oberer, Andrew T. Nelson, Srihari Konduri, Dionicio Siegel, Rudolf Zechner, Alan Saghatelian, Barbara B. Kahn

Nature. 2022; 606(7916): 968–975. Published online 2022 Jun 8. doi: 10.1038/s41586-022-04787-x

PMCID:: PMC9242854

Abstract Article PDF–12M

Select item 920741320.

The Effects of Maternal Intake of EPA and DHA Enriched Diet During Pregnancy and Lactation on Offspring’s Muscle Development and Energy Homeostasis

Saeed Ghnaimawi, Shilei Zhang, Jamie I. Baum, Yan Huang

Front Physiol. 2022; 13: 881624. Published online 2022 Jun 6. doi: 10.3389/fphys.2022.881624

PMCID:: PMC9207413

Abstract Article PDF–6.0M

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