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Select item 110185261.

Enhancer–promoter interactions become more instructive in the transition from cell-fate specification to tissue differentiation

Tim Pollex, Adam Rabinowitz, Maria Cristina Gambetta, Raquel Marco-Ferreres, Rebecca R. Viales, Aleksander Jankowski, Christoph Schaub, Eileen E. M. Furlong

Nat Genet. 2024; 56(4): 686–696. Published online 2024 Mar 11. doi: 10.1038/s41588-024-01678-x

PMCID:: PMC11018526

Abstract Article PDF–7.7M

Select item 103916752.

The tardigrade Dsup protein enhances radioresistance in Drosophila melanogaster and acts as an unspecific repressor of transcription

Mikhail Zarubin, Talyana Azorskaya, Olga Kuldoshina, Sergey Alekseev, Semen Mitrofanov, Elena Kravchenko

iScience. 2023 Jul 21; 26(7): 106998. Published online 2023 May 29. doi: 10.1016/j.isci.2023.106998

PMCID:: PMC10391675

Abstract Article PDF–3.0M

Select item 96683343.

Genetic architecture of natural variation of cardiac performance from flies to humans

Saswati Saha, Lionel Spinelli, Jaime A Castro Mondragon, Anaïs Kervadec, Michaela Lynott, Laurent Kremmer, Laurence Roder, Sallouha Krifa, Magali Torres, Christine Brun, Georg Vogler, Rolf Bodmer, Alexandre R Colas, Karen Ocorr, Laurent Perrin

eLife. 2022; 11: e82459. Published online 2022 Nov 16. doi: 10.7554/eLife.82459

PMCID:: PMC9668334

Abstract Article PDF–4.8M

Select item 96356444.

Enteric bacterial infection in Drosophila induces whole-body alterations in metabolic gene expression independently of the immune deficiency signaling pathway

Rujuta Deshpande, Byoungchun Lee, Savraj S Grewal

G3 (Bethesda) 2022 Nov; 12(11): jkac163. Published online 2022 Jul 4. doi: 10.1093/g3journal/jkac163

PMCID:: PMC9635644

Abstract Article PDF–2.2M

Select item 90183825.

Thermodynamics-based modeling reveals regulatory effects of indirect transcription factor-DNA binding

Shounak Bhogale, Saurabh Sinha

iScience. 2022 May 20; 25(5): 104152. Published online 2022 Mar 24. doi: 10.1016/j.isci.2022.104152

PMCID:: PMC9018382

Abstract Article PDF–2.0M

Select item 88933216.

Simultaneous cellular and molecular phenotyping of embryonic mutants using single-cell regulatory trajectories

Stefano Secchia, Mattia Forneris, Tobias Heinen, Oliver Stegle, Eileen E.M. Furlong

Dev Cell. 2022 Feb 28; 57(4): 496–511.e8. doi: 10.1016/j.devcel.2022.01.016

PMCID:: PMC8893321

Abstract Article

Select item 86865237.

Quantitative-enhancer-FACS-seq (QeFS) reveals epistatic interactions among motifs within transcriptional enhancers in developing Drosophila tissue

Colin T. Waters, Stephen S. Gisselbrecht, Yuliya A. Sytnikova, Tiziana M. Cafarelli, David E. Hill, Martha L. Bulyk

Genome Biol. 2021; 22: 348. Published online 2021 Dec 20. doi: 10.1186/s13059-021-02574-x

PMCID:: PMC8686523

Abstract Article PDF–1.7M

Select item 83870268.

Extremely rapid and reversible optogenetic perturbation of nuclear proteins in living embryos

Anna C. Kögler, Yacine Kherdjemil, Katharina Bender, Adam Rabinowitz, Raquel Marco-Ferreres, Eileen E.M. Furlong

Dev Cell. 2021 Aug 23; 56(16): 2348–2363.e8. doi: 10.1016/j.devcel.2021.07.011

PMCID:: PMC8387026

Abstract Article

Select item 78006059.

Polycomb and Trithorax Group Proteins: The Long Road from Mutations in Drosophila to Use in Medicine

D. A. Chetverina, D. V. Lomaev, M. M. Erokhin

Acta Naturae. 2020 Oct-Dec; 12(4): 66–85. doi: 10.32607/actanaturae.11090

PMCID:: PMC7800605

Abstract Article PDF–2.9M

Select item 726899710.

Collective Migrations of Drosophila Embryonic Trunk and Caudal Mesoderm-Derived Muscle Precursor Cells

Jingjing Sun, Frank Macabenta, Zsuzsa Akos, Angelike Stathopoulos

Genetics. 2020 Jun; 215(2): 297–322. Published online 2020 Apr 22. doi: 10.1534/genetics.120.303258

PMCID:: PMC7268997

Abstract Article PDF–2.3M

Select item 726440311.

Dynamics of Gene Co-expression Networks in Time-Series Data: A Case Study in Drosophila melanogaster Embryogenesis

Li Yieng Lau, Antonio Reverter, Nicholas J. Hudson, Marina Naval-Sanchez, Marina R. S. Fortes, Pâmela A. Alexandre

Front Genet. 2020; 11: 517. Published online 2020 May 26. doi: 10.3389/fgene.2020.00517

PMCID:: PMC7264403

Abstract Article PDF–2.4M

Select item 696157812.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 660186813.

The Role of Chromatin Accessibility in cis-Regulatory Evolution

Pei-Chen Peng, Pierre Khoueiry, Charles Girardot, James P Reddington, David A Garfield, Eileen E M Furlong, Saurabh Sinha

Genome Biol Evol. 2019 Jul; 11(7): 1813–1828. Published online 2019 May 22. doi: 10.1093/gbe/evz103

PMCID:: PMC6601868

Abstract Article PDF–951K

Select item 648595614.

A Comprehensive Drosophila melanogaster Transcription Factor Interactome

Leila Shokri, Sachi Inukai, Antonina Hafner, Kathryn Weinand, Korneel Hens, Anastasia Vedenko, Stephen S. Gisselbrecht, Riccardo Dainese, Johannes Bischof, Edy Furger, Jean-Daniel Feuz, Konrad Basler, Bart Deplancke, Martha L. Bulyk

Cell Rep. Author manuscript; available in PMC 2019 Apr 26.

Published in final edited form as: Cell Rep. 2019 Apr 16; 27(3): 955–970.e7. doi: 10.1016/j.celrep.2019.03.071

PMCID:: PMC6485956

Abstract Article PDF–1.6M

Select item 617725715.

Generation of a versatile BiFC ORFeome library for analyzing protein–protein interactions in live Drosophila

Johannes Bischof, Marilyne Duffraisse, Edy Furger, Leiore Ajuria, Guillaume Giraud, Solene Vanderperre, Rachel Paul, Mikael Björklund, Damien Ahr, Alexis W Ahmed, Lionel Spinelli, Christine Brun, Konrad Basler, Samir Merabet

eLife. 2018; 7: e38853. Published online 2018 Sep 24. doi: 10.7554/eLife.38853

PMCID:: PMC6177257

Abstract Article PDF–4.9M

Select item 570780516.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 568900217.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 555027618.

Uncoupling evolutionary changes in DNA sequence, transcription factor occupancy and enhancer activity

Pierre Khoueiry, Charles Girardot, Lucia Ciglar, Pei-Chen Peng, E Hilary Gustafson, Saurabh Sinha, Eileen EM Furlong

eLife. 2017; 6: e28440. Published online 2017 Aug 9. doi: 10.7554/eLife.28440

PMCID:: PMC5550276

Abstract Article PDF–2.7M

Select item 539363319.

The Zic family homologue Odd-paired regulates Alk expression in Drosophila

Patricia Mendoza-García, Fredrik Hugosson, Mahsa Fallah, Michael L. Higgins, Yasuno Iwasaki, Kathrin Pfeifer, Georg Wolfstetter, Gaurav Varshney, Dmitry Popichenko, J. Peter Gergen, Korneel Hens, Bart Deplancke, Ruth H. Palmer

PLoS Genet. 2017 Apr; 13(4): e1006617. Published online 2017 Apr 3. doi: 10.1371/journal.pgen.1006617

PMCID:: PMC5393633

Abstract Article PDF–6.4M

Select item 501270120.

Qualitative Dynamical Modelling Can Formally Explain Mesoderm Specification and Predict Novel Developmental Phenotypes

Abibatou Mbodj, E. Hilary Gustafson, Lucia Ciglar, Guillaume Junion, Aitor Gonzalez, Charles Girardot, Laurent Perrin, Eileen E. M. Furlong, Denis Thieffry

PLoS Comput Biol. 2016 Sep; 12(9): e1005073. Published online 2016 Sep 6. doi: 10.1371/journal.pcbi.1005073