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Select item 111999131.

High sugar diet–induced fatty acid oxidation potentiates cytokine-dependent cardiac ECM remodeling

Jayati Gera, Dheeraj Kumar, Gunjan Chauhan, Adarsh Choudhary, Lavi Rani, Lolitika Mandal, Sudip Mandal

J Cell Biol. 2024 Sep 2; 223(9): e202306087. Published online 2024 Jun 25. doi: 10.1083/jcb.202306087

PMCID:: PMC11199913

Abstract Article PDF–8.6M

Select item 111720852.

Cholesterol Dietary Intake and Tumor Cell Homeostasis Drive Early Epithelial Tumorigenesis: A Potential Modelization of Early Prostate Tumorigenesis

Marine Vialat, Elissa Baabdaty, Amalia Trousson, Ayhan Kocer, Jean-Marc A. Lobaccaro, Silvère Baron, Laurent Morel, Cyrille de Joussineau

Cancers (Basel) 2024 Jun; 16(11): 2153. Published online 2024 Jun 6. doi: 10.3390/cancers16112153

PMCID:: PMC11172085

Abstract Article PDF–11M

Select item 111165283.

A nutrient responsive lipase mediates gut-brain communication to regulate insulin secretion in Drosophila

Alka Singh, Kandahalli Venkataranganayaka Abhilasha, Kathya R. Acharya, Haibo Liu, Niraj K. Nirala, Velayoudame Parthibane, Govind Kunduri, Thiruvaimozhi Abimannan, Jacob Tantalla, Lihua Julie Zhu, Jairaj K. Acharya, Usha R. Acharya

Nat Commun. 2024; 15: 4410. Published online 2024 May 23. doi: 10.1038/s41467-024-48851-8

PMCID:: PMC11116528

Abstract Article PDF–8.0M

Select item 107635324.

Lipophorin receptors genetically modulate neurodegeneration caused by reduction of Psn expression in the aging Drosophila brain

Jongkyun Kang, Chen Zhang, Yuhao Wang, Jian Peng, Bonnie Berger, Norbert Perrimon, Jie Shen

Genetics. 2024 Jan; 226(1): iyad202. Published online 2023 Nov 23. doi: 10.1093/genetics/iyad202

PMCID:: PMC10763532

Abstract Article PDF–1.5M

Select item 105756295.

Chromatin and gene expression changes during female Drosophila germline stem cell development illuminate the biology of highly potent stem cells

Liang-Yu Pang, Steven DeLuca, Haolong Zhu, John M Urban, Allan C Spradling

eLife. 2023; 12: RP90509. Published online 2023 Oct 13. doi: 10.7554/eLife.90509

PMCID:: PMC10575629

Abstract Article PDF–6.3M

Select item 104491646.

Drosophila embryos allocate lipid droplets to specific lineages to ensure punctual development and redox homeostasis

Marcus D. Kilwein, T. Kim Dao, Michael A. Welte

PLoS Genet. 2023 Aug; 19(8): e1010875. Published online 2023 Aug 14. doi: 10.1371/journal.pgen.1010875

PMCID:: PMC10449164

Abstract Article PDF–5.1M

Select item 99749367.

From Worms to Humans: Understanding Intestinal Lipid Metabolism via Model Organisms

Darby W. Kozan, Joshua T. Derrick, William B. Ludington, Steven A. Farber

Biochim Biophys Acta Mol Cell Biol Lipids. Author manuscript; available in PMC 2024 Apr 1.

Published in final edited form as: Biochim Biophys Acta Mol Cell Biol Lipids. 2023 Apr; 1868(4): 159290. Published online 2023 Feb 3. doi: 10.1016/j.bbalip.2023.159290

PMCID:: PMC9974936

Abstract Article PDF–1.5M

Select item 94541258.

Lipophorin receptors regulate mushroom body development and complex behaviors in Drosophila

Francisca Rojo-Cortés, Nicolás Fuenzalida-Uribe, Victoria Tapia-Valladares, Candy B. Roa, Sergio Hidalgo, María-Constanza González-Ramírez, Carlos Oliva, Jorge M. Campusano, María-Paz Marzolo

BMC Biol. 2022; 20: 198. Published online 2022 Sep 7. doi: 10.1186/s12915-022-01393-1

PMCID:: PMC9454125

Abstract Article PDF–5.7M

Select item 92396809.

An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR-mediated homologous recombination

Oguz Kanca, Jonathan Zirin, Yanhui Hu, Burak Tepe, Debdeep Dutta, Wen-Wen Lin, Liwen Ma, Ming Ge, Zhongyuan Zuo, Lu-Ping Liu, Robert W Levis, Norbert Perrimon, Hugo J Bellen

eLife. 2022; 11: e76077. Published online 2022 Jun 20. doi: 10.7554/eLife.76077

PMCID:: PMC9239680

Abstract Article PDF–1.2M

Select item 920864810.

microRNA-252 and FoxO repress inflammaging by a dual inhibitory mechanism on Dawdle-mediated TGF-β pathway in Drosophila

Xiaofen Wu, Kongyan Niu, Xiaofan Wang, Jing Zhao, Han Wang, Dean Li, Hui Wang, Ting Miao, Yun Yang, Huanhuan Ma, Yaoyang Zhang, Lei Pan, Rui Liu, Hua Bai, Nan Liu

Genetics. 2022 Mar; 220(3): iyab234. Published online 2021 Dec 21. doi: 10.1093/genetics/iyab234

PMCID:: PMC9208648

Abstract Article PDF–1.5M

Select item 871988511.

Neuronal ROS-induced glial lipid droplet formation is altered by loss of Alzheimer’s disease–associated genes

Matthew J. Moulton, Scott Barish, Isha Ralhan, Jinlan Chang, Lindsey D. Goodman, Jake G. Harland, Paul C. Marcogliese, Jan O. Johansson, Maria S. Ioannou, Hugo J. Bellen

Proc Natl Acad Sci U S A. 2021 Dec 28; 118(52): e2112095118. Published online 2021 Dec 23. doi: 10.1073/pnas.2112095118

PMCID:: PMC8719885

Abstract Article PDF–2.8M

Select item 866448612.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 846882713.

Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders

Stefano Sechi, Angela Karimpour-Ghahnavieh, Anna Frappaolo, Laura Di Francesco, Roberto Piergentili, Eugenia Schininà, Pier Paolo D’Avino, Maria Grazia Giansanti

Cells. 2021 Sep; 10(9): 2336. Published online 2021 Sep 6. doi: 10.3390/cells10092336

PMCID:: PMC8468827

Abstract Article PDF–4.1M

Select item 788512014.

Wolbachia and Virus Alter the Host Transcriptome at the Interface of Nucleotide Metabolism Pathways

Amelia R. I. Lindsey, Tamanash Bhattacharya, Richard W. Hardy, Irene L. G. Newton

mBio. 2021 Jan-Feb; 12(1): e03472-20. Published online 2021 Feb 9. doi: 10.1128/mBio.03472-20

PMCID:: PMC7885120

Abstract Article PDF–3.5M

Select item 770463415.

An original infection model identifies host lipoprotein import as a route for blood-brain barrier crossing

Billel Benmimoun, Florentia Papastefanaki, Bruno Périchon, Katerina Segklia, Nicolas Roby, Vivi Miriagou, Christine Schmitt, Shaynoor Dramsi, Rebecca Matsas, Pauline Spéder

Nat Commun. 2020; 11: 6106. Published online 2020 Nov 30. doi: 10.1038/s41467-020-19826-2

PMCID:: PMC7704634

Abstract Article PDF–5.3M

Select item 761084116.

Glypicans shield the Wnt lipid moiety to enable signalling at a distance

Ian J. McGough, Luca Vecchia, Benjamin Bishop, Tomas Malinauskas, Karen Beckett, Dhira Joshi, Nicola O'Reilly, Christian Siebold, E. Yvonne Jones, Jean-Paul Vincent

Nature. Author manuscript; available in PMC 2021 May 25.

Published in final edited form as: Nature. 2020 Sep 1; 585(7823): 85–90. Published online 2020 Jul 22. doi: 10.1038/s41586-020-2498-z

PMCID:: PMC7610841

Abstract Article PDF–6.7M

Select item 747962017.

Single-cell transcriptome maps of myeloid blood cell lineages in Drosophila

Bumsik Cho, Sang-Ho Yoon, Daewon Lee, Ferdinand Koranteng, Sudhir Gopal Tattikota, Nuri Cha, Mingyu Shin, Hobin Do, Yanhui Hu, Sue Young Oh, Daehan Lee, A. Vipin Menon, Seok Jun Moon, Norbert Perrimon, Jin-Wu Nam, Jiwon Shim

Nat Commun. 2020; 11: 4483. Published online 2020 Sep 8. doi: 10.1038/s41467-020-18135-y

PMCID:: PMC7479620

Abstract Article PDF–11M

Select item 732192418.

Single-cell RNA sequencing identifies novel cell types in Drosophila blood

Yulong Fu, Xiaohu Huang, Peng Zhang, Joyce van de Leemput, Zhe Han

J Genet Genomics. Author manuscript; available in PMC 2021 Apr 20.

Published in final edited form as: J Genet Genomics. 2020 Apr 20; 47(4): 175–186. Published online 2020 Mar 9. doi: 10.1016/j.jgg.2020.02.004

PMCID:: PMC7321924

Abstract Article PDF–2.6M

Select item 696157819.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 695530420.

An in vivo RNAi screen uncovers the role of AdoR signaling and adenosine deaminase in controlling intestinal stem cell activity

Chiwei Xu, Brian Franklin, Hong-Wen Tang, Yannik Regimbald-Dumas, Yanhui Hu, Justine Ramos, Justin A. Bosch, Christians Villalta, Xi He, Norbert Perrimon

Proc Natl Acad Sci U S A. 2020 Jan 7; 117(1): 464–471. Published online 2019 Dec 18. doi: 10.1073/pnas.1900103117