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Select item 113624591.

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation

Lisa Kofler, Lorenz Grundmann, Magdalena Gerhalter, Michael Prattes, Juliane Merl-Pham, Gertrude Zisser, Irina Grishkovskaya, Victor-Valentin Hodirnau, Martin Vareka, Rolf Breinbauer, Stefanie M. Hauck, David Haselbach, Helmut Bergler

Nat Commun. 2024; 15: 7511. Published online 2024 Aug 29. doi: 10.1038/s41467-024-51754-3

PMCID:: PMC11362459

Abstract Article PDF–3.5M

Select item 108724772.

Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle

Michael J. O’Brien, Athar Ansari

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968

PMCID:: PMC10872477

Abstract Article PDF–1.7M

Select item 108687273.

Adaptive preservation of orphan ribosomal proteins in chaperone-dispersed condensates

Asif Ali, Rania Garde, Olivia C. Schaffer, Jared A. M. Bard, Kabir Husain, Samantha Keyport Kik, Kathleen A. Davis, Sofia Luengo-Woods, Maya G. Igarashi, D. Allan Drummond, Allison H. Squires, David Pincus

Nat Cell Biol. Author manuscript; available in PMC 2024 Feb 15.

Published in final edited form as: Nat Cell Biol. 2023 Nov; 25(11): 1691–1703. Published online 2023 Oct 16. doi: 10.1038/s41556-023-01253-2

PMCID:: PMC10868727

Abstract Article PDF–7.0M

Select item 107988584.

Fast-evolving cofactors regulate the role of HEATR5 complexes in intra-Golgi trafficking

Lucas J. Marmorale, Huan Jin, Thomas G. Reidy, Brandon Palomino-Alonso, Christopher J. Zysnarski, Fatima Jordan-Javed, Sagar Lahiri, Mara C. Duncan

J Cell Biol. 2024 Mar 4; 223(3): e202309047. Published online 2024 Jan 19. doi: 10.1083/jcb.202309047

PMCID:: PMC10798858

Abstract Article PDF–6.4M

Select item 107001385.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 102977006.

The Hsp90 molecular chaperone governs client proteins by targeting intrinsically disordered regions

Janhavi A. Kolhe, Neethu L. Babu, Brian C. Freeman

Mol Cell. Author manuscript; available in PMC 2024 Jun 15.

Published in final edited form as: Mol Cell. 2023 Jun 15; 83(12): 2035–2044.e7. Published online 2023 Jun 8. doi: 10.1016/j.molcel.2023.05.021

PMCID:: PMC10297700

Abstract Article PDF–2.0M

Select item 102922107.

Nuclear pore complexes mediate subtelomeric gene silencing by regulating PCNA levels on chromatin

Sanjeev Kumar Choudhry, Maxwell L. Neal, Song Li, Arti T. Navare, Trevor Van Eeuwen, Richard W. Wozniak, Fred D. Mast, Michael P. Rout, John D. Aitchison

J Cell Biol. 2023 Sep 4; 222(9): e202207060. Published online 2023 Jun 26. doi: 10.1083/jcb.202207060

PMCID:: PMC10292210

Abstract Article PDF–5.9M

Select item 102333688.

A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Nir Cohen, Naama Aviram, Maya Schuldiner

EMBO J. 2023 Jun; 42(11): e113385. Published online 2023 Apr 19. doi: 10.15252/embj.2022113385

PMCID:: PMC10233368

Abstract Article PDF–1.2M

Select item 98363489.

A synthetic genetic array screen for interactions with the RNA helicase DED1 during cell stress in budding yeast

Sara B Carey, Hannah M List, Ashwin Siby, Paolo Guerra, Timothy A Bolger

G3 (Bethesda) 2023 Jan; 13(1): jkac296. Published online 2022 Nov 21. doi: 10.1093/g3journal/jkac296

PMCID:: PMC9836348

Abstract Article PDF–857K

Select item 963098610.

A balancing act: interactions within NuA4/TIP60 regulate picNuA4 function in Saccharomyces cerevisiae and humans

Phoebe Y T Lu, Alyssa C Kirlin, Maria J Aristizabal, Hilary T Brewis, Nancy Lévesque, Dheva T Setiaputra, Nikita Avvakumov, Joris J Benschop, Marian Groot Koerkamp, Frank C P Holstege, Nevan J Krogan, Calvin K Yip, Jacques Côté, Michael S Kobor

Genetics. 2022 Nov; 222(3): iyac136. Published online 2022 Sep 6. doi: 10.1093/genetics/iyac136

PMCID:: PMC9630986

Abstract Article PDF–2.2M

Select item 920981111.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 916991312.

The ubiquitin–proteasome system regulates meiotic chromosome organization

Xiao Yang, Meihui Song, Ying Wang, Taicong Tan, Zhongyu Tian, Binyuan Zhai, Xuan Yang, Yingjin Tan, Yanding Cao, Shaojun Dai, Shunxin Wang, Liangran Zhang

Proc Natl Acad Sci U S A. 2022 Apr 26; 119(17): e2106902119. Published online 2022 Apr 19. doi: 10.1073/pnas.2106902119

PMCID:: PMC9169913

Abstract Article PDF–2.1M

Select item 900791713.

Identification of 14-3-3 Proteins, Polo kinase, and RNA-binding protein Pes4 as Key Regulators of Meiotic Commitment in Budding Yeast

Janardan N. Gavade, Chris M. Puccia, S. Grace Herod, Jonathan C. Trinidad, Luke E. Berchowitz, Soni Lacefield

Curr Biol. Author manuscript; available in PMC 2023 Apr 11.

Published in final edited form as: Curr Biol. 2022 Apr 11; 32(7): 1534–1547.e9. Published online 2022 Mar 2. doi: 10.1016/j.cub.2022.02.022

PMCID:: PMC9007917

Abstract Article PDF–2.2M

Select item 829842414.

Harmful R-loops are prevented via different cell cycle-specific mechanisms

Marta San Martin-Alonso, María E. Soler-Oliva, María García-Rubio, Tatiana García-Muse, Andrés Aguilera

Nat Commun. 2021; 12: 4451. Published online 2021 Jul 22. doi: 10.1038/s41467-021-24737-x

PMCID:: PMC8298424

Abstract Article PDF–2.2M

Select item 805335515.

The endoplasmic reticulum P5A-ATPase is a transmembrane helix dislocase

Michael J. McKenna, Sue Im Sim, Alban Ordureau, Lianjie Wei, J. Wade Harper, Sichen Shao, Eunyong Park

Science. Author manuscript; available in PMC 2021 Apr 18.

Published in final edited form as: Science. 2020 Sep 25; 369(6511): eabc5809. doi: 10.1126/science.abc5809

PMCID:: PMC8053355

Abstract Article PDF–1.7M

Select item 784292716.

Highly exposed segment of the Spf1p P5A-ATPase near transmembrane M5 detected by limited proteolysis

Guido D. Petrovich, Gerardo R. Corradi, Carlos H. Pavan, Sofia Noli Truant, Hugo P. Adamo

PLoS One. 2021; 16(1): e0245679. Published online 2021 Jan 28. doi: 10.1371/journal.pone.0245679

Correction in:: PLoS One. 2021; 16(8): e0256945.

PMCID:: PMC7842927

Abstract Article PDF–2.7M

Select item 719238817.

Reduction of the P5A-ATPase Spf1p phosphoenzyme by a Ca²⁺-dependent phosphatase

Gerardo R. Corradi, Luciana R. Mazzitelli, Guido D. Petrovich, Paula Grenon, Danny M. Sørensen, Michael Palmgren, Felicitas de Tezanos Pinto, Hugo P. Adamo

PLoS One. 2020; 15(4): e0232476. Published online 2020 Apr 30. doi: 10.1371/journal.pone.0232476

PMCID:: PMC7192388

Abstract Article PDF–1.9M

Select item 694080418.

Translational Regulation of Pmt1 and Pmt2 by Bfr1 Affects Unfolded Protein O-Mannosylation

Joan Castells-Ballester, Natalie Rinis, Ilgin Kotan, Lihi Gal, Daniela Bausewein, Ilia Kats, Ewa Zatorska, Günter Kramer, Bernd Bukau, Maya Schuldiner, Sabine Strahl

Int J Mol Sci. 2019 Dec; 20(24): 6220. Published online 2019 Dec 10. doi: 10.3390/ijms20246220

PMCID:: PMC6940804

Abstract Article PDF–2.9M

Select item 672451019.

The P5A ATPase Spf1p is stimulated by phosphatidylinositol 4-phosphate and influences cellular sterol homeostasis

Danny Mollerup Sørensen, Henrik Waldal Holen, Jesper Torbøl Pedersen, Helle Juel Martens, Daniele Silvestro, Lyubomir Dimitrov Stanchev, Sara Rute Costa, Thomas Günther Pomorski, Rosa Laura López-Marqués, Michael Palmgren

Mol Biol Cell. 2019 Apr 15; 30(9): 1069–1084. doi: 10.1091/mbc.E18-06-0365

PMCID:: PMC6724510

Abstract Article PDF–2.3M

Select item 668908620.

The Hsp90 isoforms from S. cerevisiae differ in structure, function and client range

Hannah Girstmair, Franziska Tippel, Abraham Lopez, Katarzyna Tych, Frank Stein, Per Haberkant, Philipp Werner Norbert Schmid, Dominic Helm, Matthias Rief, Michael Sattler, Johannes Buchner

Nat Commun. 2019; 10: 3626. Published online 2019 Aug 9. doi: 10.1038/s41467-019-11518-w