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Select item 113624591.

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation

Lisa Kofler, Lorenz Grundmann, Magdalena Gerhalter, Michael Prattes, Juliane Merl-Pham, Gertrude Zisser, Irina Grishkovskaya, Victor-Valentin Hodirnau, Martin Vareka, Rolf Breinbauer, Stefanie M. Hauck, David Haselbach, Helmut Bergler

Nat Commun. 2024; 15: 7511. Published online 2024 Aug 29. doi: 10.1038/s41467-024-51754-3

PMCID:: PMC11362459

Abstract Article PDF–3.5M

Select item 108997792.

The RNA helicase Dbp10 coordinates assembly factor association with PTC maturation during ribosome biogenesis

Valentin Mitterer, Hussein Hamze, Natalia Kunowska, Ulrich Stelzl, Anthony K Henras, Ed Hurt

Nucleic Acids Res. 2024 Feb 28; 52(4): 1975–1987. Published online 2023 Dec 19. doi: 10.1093/nar/gkad1206

PMCID:: PMC10899779

Abstract Article PDF–1.6M

Select item 108724773.

Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle

Michael J. O’Brien, Athar Ansari

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968

PMCID:: PMC10872477

Abstract Article PDF–1.7M

Select item 107988584.

Fast-evolving cofactors regulate the role of HEATR5 complexes in intra-Golgi trafficking

Lucas J. Marmorale, Huan Jin, Thomas G. Reidy, Brandon Palomino-Alonso, Christopher J. Zysnarski, Fatima Jordan-Javed, Sagar Lahiri, Mara C. Duncan

J Cell Biol. 2024 Mar 4; 223(3): e202309047. Published online 2024 Jan 19. doi: 10.1083/jcb.202309047

PMCID:: PMC10798858

Abstract Article PDF–6.4M

Select item 107001385.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 106390616.

Yeast ribosome biogenesis factors Puf6 and Nog2 and ribosomal proteins uL2 and eL43 act in concert to facilitate the release of nascent large ribosomal subunits from the nucleolus

Amber J LaPeruta, Stefanie Hedayati, Jelena Micic, Fiona Fitzgerald, David Kim, Grace Oualline, John L Woolford

Nucleic Acids Res. 2023 Nov 10; 51(20): 11277–11290. Published online 2023 Oct 9. doi: 10.1093/nar/gkad794

PMCID:: PMC10639061

Abstract Article PDF–3.7M

Select item 102333687.

A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Nir Cohen, Naama Aviram, Maya Schuldiner

EMBO J. 2023 Jun; 42(11): e113385. Published online 2023 Apr 19. doi: 10.15252/embj.2022113385

PMCID:: PMC10233368

Abstract Article PDF–1.2M

Select item 101540288.

Concurrent remodelling of nucleolar 60S subunit precursors by the Rea1 ATPase and Spb4 RNA helicase

Valentin Mitterer, Matthias Thoms, Robert Buschauer, Otto Berninghausen, Ed Hurt, Roland Beckmann

eLife. 2023; 12: e84877. Published online 2023 Mar 17. doi: 10.7554/eLife.84877

PMCID:: PMC10154028

Abstract Article PDF–9.4M

Select item 98363489.

A synthetic genetic array screen for interactions with the RNA helicase DED1 during cell stress in budding yeast

Sara B Carey, Hannah M List, Ashwin Siby, Paolo Guerra, Timothy A Bolger

G3 (Bethesda) 2023 Jan; 13(1): jkac296. Published online 2022 Nov 21. doi: 10.1093/g3journal/jkac296

PMCID:: PMC9836348

Abstract Article PDF–857K

Select item 950796910.

Visualizing maturation factor extraction from the nascent ribosome by the AAA-ATPase Drg1

Michael Prattes, Irina Grishkovskaya, Victor-Valentin Hodirnau, Christina Hetzmannseder, Gertrude Zisser, Carolin Sailer, Vasileios Kargas, Mathias Loibl, Magdalena Gerhalter, Lisa Kofler, Alan J. Warren, Florian Stengel, David Haselbach, Helmut Bergler

Nat Struct Mol Biol. 2022; 29(9): 942–953. Published online 2022 Sep 12. doi: 10.1038/s41594-022-00832-5

PMCID:: PMC9507969

Abstract Article PDF–9.4M

Select item 920981111.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 851195012.

The histone chaperone Spt6 is required for normal recruitment of the capping enzyme Abd1 to transcribed regions

Rajaraman Gopalakrishnan, Fred Winston

J Biol Chem. 2021 Oct; 297(4): 101205. Published online 2021 Sep 17. doi: 10.1016/j.jbc.2021.101205

PMCID:: PMC8511950

Abstract Article PDF–3.1M

Select item 833894113.

Puf6 primes 60S pre-ribosome nuclear export at low temperature

Stefan Gerhardy, Michaela Oborská-Oplová, Ludovic Gillet, Richard Börner, Rob van Nues, Alexander Leitner, Erich Michel, Janusz J. Petkowski, Sander Granneman, Roland K. O. Sigel, Ruedi Aebersold, Vikram Govind Panse

Nat Commun. 2021; 12: 4696. Published online 2021 Aug 4. doi: 10.1038/s41467-021-24964-2

PMCID:: PMC8338941

Abstract Article PDF–5.7M

Select item 773068714.

Mutational Analysis of the Nsa2 N-Terminus Reveals Its Essential Role in Ribosomal 60S Subunit Assembly

Helge Paternoga, Alexander Früh, Ruth Kunze, Bettina Bradatsch, Jochen Baßler, Ed Hurt

Int J Mol Sci. 2020 Dec; 21(23): 9108. Published online 2020 Nov 30. doi: 10.3390/ijms21239108

PMCID:: PMC7730687

Abstract Article PDF–3.1M

Select item 768298815.

The deubiquitylase Ubp15 couples transcription to mRNA export

Fanny Eyboulet, Célia Jeronimo, Jacques Côté, François Robert

eLife. 2020; 9: e61264. Published online 2020 Nov 23. doi: 10.7554/eLife.61264

PMCID:: PMC7682988

Abstract Article PDF–1.4M

Select item 754769016.

Structural insights into assembly of the ribosomal nascent polypeptide exit tunnel

Daniel M. Wilson, Yu Li, Amber LaPeruta, Michael Gamalinda, Ning Gao, John L. Woolford, Jr

Nat Commun. 2020; 11: 5111. Published online 2020 Oct 9. doi: 10.1038/s41467-020-18878-8

PMCID:: PMC7547690

Abstract Article PDF–3.4M

Select item 738508417.

Coupling of 5S RNP rotation with maturation of functional centers during large ribosomal subunit assembly

Jelena Micic, Yu Li, Shan Wu, Daniel Wilson, Beril Tutuncuoglu, Ning Gao, John L. Woolford, Jr.

Nat Commun. 2020; 11: 3751. Published online 2020 Jul 27. doi: 10.1038/s41467-020-17534-5

PMCID:: PMC7385084

Abstract Article PDF–4.6M

Select item 729303918.

The ribotoxin α-sarcin can cleave the sarcin/ricin loop on late 60S pre-ribosomes

Miriam Olombrada, Cohue Peña, Olga Rodríguez-Galán, Purnima Klingauf-Nerurkar, Daniela Portugal-Calisto, Michaela Oborská-Oplová, Martin Altvater, José G Gavilanes, Álvaro Martínez-del-Pozo, Jesús de la Cruz, Lucía García-Ortega, Vikram Govind Panse

Nucleic Acids Res. 2020 Jun 19; 48(11): 6210–6222. Published online 2020 May 4. doi: 10.1093/nar/gkaa315

PMCID:: PMC7293039

Abstract Article PDF–12M

Select item 679513819.

The L1 stalk is required for efficient export of nascent large ribosomal subunits in yeast

Sharmishtha Musalgaonkar, Joshua J. Black, Arlen W. Johnson

RNA. 2019 Nov; 25(11): 1549–1560. doi: 10.1261/rna.071811.119

PMCID:: PMC6795138

Abstract Article PDF–5.2M

Select item 664889520.

Tsr4 and Nap1, two novel members of the ribosomal protein chaperOME

Ingrid Rössler, Julia Embacher, Benjamin Pillet, Guillaume Murat, Laura Liesinger, Jutta Hafner, Julia Judith Unterluggauer, Ruth Birner-Gruenberger, Dieter Kressler, Brigitte Pertschy

Nucleic Acids Res. 2019 Jul 26; 47(13): 6984–7002. Published online 2019 May 7. doi: 10.1093/nar/gkz317