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Select item 113992611.

Replication licensing regulated by a short linear motif within an intrinsically disordered region of origin recognition complex

Yue Wu, Qiongdan Zhang, Yuhan Lin, Wai Hei Lam, Yuanliang Zhai

Nat Commun. 2024; 15: 8039. Published online 2024 Sep 13. doi: 10.1038/s41467-024-52408-0

PMCID:: PMC11399261

Abstract Article PDF–1.5M

Select item 108724772.

Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle

Michael J. O’Brien, Athar Ansari

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968

PMCID:: PMC10872477

Abstract Article PDF–1.7M

Select item 107001383.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 106295574.

Regulation of replication origin licensing by ORC phosphorylation reveals a two-step mechanism for Mcm2-7 ring closing

Audra L. Amasino, Shalini Gupta, Larry J. Friedman, Jeff Gelles, Stephen P. Bell

Proc Natl Acad Sci U S A. 2023 Jul 18; 120(29): e2221484120. Published online 2023 Jul 10. doi: 10.1073/pnas.2221484120

PMCID:: PMC10629557

Abstract Article PDF–2.3M

Select item 102922105.

Nuclear pore complexes mediate subtelomeric gene silencing by regulating PCNA levels on chromatin

Sanjeev Kumar Choudhry, Maxwell L. Neal, Song Li, Arti T. Navare, Trevor Van Eeuwen, Richard W. Wozniak, Fred D. Mast, Michael P. Rout, John D. Aitchison

J Cell Biol. 2023 Sep 4; 222(9): e202207060. Published online 2023 Jun 26. doi: 10.1083/jcb.202207060

PMCID:: PMC10292210

Abstract Article PDF–5.9M

Select item 102333686.

A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Nir Cohen, Naama Aviram, Maya Schuldiner

EMBO J. 2023 Jun; 42(11): e113385. Published online 2023 Apr 19. doi: 10.15252/embj.2022113385

PMCID:: PMC10233368

Abstract Article PDF–1.2M

Select item 98133927.

An essential Noc3p dimerization cycle mediates ORC double-hexamer formation in replication licensing

Aftab Amin, Rentian Wu, Muhammad Ajmal Khan, Man Hei Cheung, Yanting Liang, Changdong Liu, Guang Zhu, Zhi-Ling Yu, Chun Liang

Life Sci Alliance. 2023 Mar; 6(3): e202201594. Published online 2023 Jan 4. doi: 10.26508/lsa.202201594

PMCID:: PMC9813392

Abstract Article PDF–4.3M

Select item 93392938.

Complex mutation profiles in mismatch repair and ribonucleotide reductase mutants reveal novel repair substrate specificity of MutS homolog (MSH) complexes

Natalie A Lamb, Jonathan E Bard, Raphael Loll-Krippleber, Grant W Brown, Jennifer A Surtees

Genetics. 2022 Aug; 221(4): iyac092. Published online 2022 Jun 10. doi: 10.1093/genetics/iyac092

PMCID:: PMC9339293

Abstract Article PDF–7.9M

Select item 92098119.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 888161110.

A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6

Jan Marten Schmidt, Ran Yang, Ashish Kumar, Olivia Hunker, Jan Seebacher, Franziska Bleichert

Nat Commun. 2022; 13: 1059. Published online 2022 Feb 25. doi: 10.1038/s41467-022-28695-w

PMCID:: PMC8881611

Abstract Article PDF–4.5M

Select item 857106311.

Systems-level effects of allosteric perturbations to a model molecular switch

Tina Perica, Christopher J. P. Mathy, Jiewei Xu, Gwendolyn M. Jang, Yang Zhang, Robyn Kaake, Noah Ollikainen, Hannes Braberg, Danielle L. Swaney, David G. Lambright, Mark J. S. Kelly, Nevan J. Krogan, Tanja Kortemme

Nature. Author manuscript; available in PMC 2022 May 1.

Published in final edited form as: Nature. 2021 Nov; 599(7883): 152–157. Published online 2021 Oct 13. doi: 10.1038/s41586-021-03982-6

PMCID:: PMC8571063

Abstract Article PDF–2.7M

Select item 822235712.

The structure of ORC–Cdc6 on an origin DNA reveals the mechanism of ORC activation by the replication initiator Cdc6

Xiang Feng, Yasunori Noguchi, Marta Barbon, Bruce Stillman, Christian Speck, Huilin Li

Nat Commun. 2021; 12: 3883. Published online 2021 Jun 23. doi: 10.1038/s41467-021-24199-1

PMCID:: PMC8222357

Abstract Article PDF–4.9M

Select item 804568713.

Interaction of replication factor Sld3 and histone acetyl transferase Esa1 alleviates gene silencing and promotes the activation of late and dormant replication origins

Seiji Tanaka

Genetics. 2021 Jan; 217(1): iyaa001. Published online 2020 Nov 11. doi: 10.1093/genetics/iyaa001

PMCID:: PMC8045687

Abstract Article PDF–873K

Select item 771875114.

Comprehensive Synthetic Genetic Array Analysis of Alleles That Interact with Mutation of the Saccharomyces cerevisiae RecQ Helicases Hrq1 and Sgs1

Elsbeth Sanders, Phoebe A. Nguyen, Cody M. Rogers, Matthew L. Bochman

G3 (Bethesda) 2020 Dec; 10(12): 4359–4368. Published online 2020 Oct 28. doi: 10.1534/g3.120.401709

PMCID:: PMC7718751

Abstract Article PDF–1.2M

Select item 756090215.

Evolution of DNA replication origin specification and gene silencing mechanisms

Y. Hu, A. Tareen, Y-J. Sheu, W. T. Ireland, C. Speck, H. Li, L. Joshua-Tor, J. B. Kinney, B. Stillman

Nat Commun. 2020; 11: 5175. Published online 2020 Oct 14. doi: 10.1038/s41467-020-18964-x

PMCID:: PMC7560902

Abstract Article PDF–2.4M

Select item 754073016.

INO80C Remodeler Maintains Genomic Stability by Preventing Promiscuous Transcription at Replication Origins

Salih Topal, Christopher Van, Yong Xue, Michael F. Carey, Craig L. Peterson

Cell Rep. Author manuscript; available in PMC 2020 Oct 7.

Published in final edited form as: Cell Rep. 2020 Sep 8; 32(10): 108106. doi: 10.1016/j.celrep.2020.108106

PMCID:: PMC7540730

Abstract Article PDF–1.1M

Select item 744295517.

Biochemical and functional characterization of a meiosis-specific Pch2/ORC AAA+ assembly

María Ascensión Villar-Fernández, Richard Cardoso da Silva, Magdalena Firlej, Dongqing Pan, Elisabeth Weir, Annika Sarembe, Vivek B Raina, Tanja Bange, John R Weir, Gerben Vader

Life Sci Alliance. 2020 Nov; 3(11): e201900630. Published online 2020 Aug 21. doi: 10.26508/lsa.201900630

PMCID:: PMC7442955

Abstract Article PDF–3.2M

Select item 738643318.

Dosage suppression genetic interaction networks enhance functional wiring diagrams of the cell

Leslie Magtanong, Cheuk Hei Ho, Sarah L Barker, Wei Jiao, Anastasia Baryshnikova, Sondra Bahr, Andrew M Smith, Lawrence E Heisler, John S Choy, Elena Kuzmin, Kerry Andrusiak, Anna Kobylianski, Zhijian Li, Michael Costanzo, Munira A Basrai, Guri Giaever, Corey Nislow, Brenda Andrewa, Charles Boone

Nat Biotechnol. Author manuscript; available in PMC 2020 Jul 28.

Published in final edited form as: Nat Biotechnol. 2011 May 15; 29(6): 505–511. Published online 2011 May 15. doi: 10.1038/nbt.1855

PMCID:: PMC7386433

Abstract Article PDF–1.0M

Select item 727317719.

Chaperone-Mediated Protein Disaggregation Triggers Proteolytic Clearance of Intra-nuclear Protein Inclusions

Fabian den Brave, Lucas V. Cairo, Chandhuru Jagadeesan, Carmen Ruger-Herreros, Axel Mogk, Bernd Bukau, Stefan Jentsch

Cell Rep. 2020 Jun 2; 31(9): 107680. Published online 2020 Jun 2. doi: 10.1016/j.celrep.2020.107680

PMCID:: PMC7273177

Abstract Article

Select item 612066820.

Rtt105 functions as a chaperone for replication protein A to preserve genome stability

Shuqi Li, Zhiyun Xu, Jiawei Xu, Linyu Zuo, Chuanhe Yu, Pu Zheng, Haiyun Gan, Xuezheng Wang, Longtu Li, Sushma Sharma, Andrei Chabes, Di Li, Sheng Wang, Sihao Zheng, Jinbao Li, Xuefeng Chen, Yujie Sun, Dongyi Xu, Junhong Han, Kuiming Chan, Zhi Qi, Jianxun Feng, Qing Li

EMBO J. 2018 Sep 3; 37(17): e99154. Published online 2018 Jul 31. doi: 10.15252/embj.201899154

PMCID:: PMC6120668

Abstract Article PDF–2.3M

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