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Items: 1 to 20 of 292

1.
Tgfbr1 controls developmental plasticity between the hindlimb and external genitalia by remodeling their regulatory landscape
Anastasiia Lozovska, Artemis G. Korovesi, André Dias, Alexandre Lopes, Donald A. Fowler, Gabriel G. Martins, Ana Nóvoa, Moisés Mallo
Nat Commun. 2024; 15: 2509. Published online 2024 Mar 20. doi: 10.1038/s41467-024-46870-z
PMCID:
PMC10954616
AbstractArticlePDF–9.6M
2.
Nigral transcriptomic profiles in Engrailed-1 hemizygous mouse models of Parkinson’s disease reveal upregulation of oxidative phosphorylation-related genes associated with delayed dopaminergic neurodegeneration
Lautaro Francisco Belfiori, Alfredo Dueñas Rey, Dorottya Mária Ralbovszki, Itzia Jimenez-Ferrer, Filip Fredlund, Sagar Shivayogi Balikai, Dag Ahrén, Kajsa Atterling Brolin, Maria Swanberg
Front Aging Neurosci. 2024; 16: 1337365. Published online 2024 Feb 5. doi: 10.3389/fnagi.2024.1337365
PMCID:
PMC10875038
AbstractArticlePDF–4.6M
3.
Neuronal DSCAM regulates the peri-synaptic localization of GLAST in Bergmann glia for functional synapse formation
Ken-ichi Dewa, Nariko Arimura, Wataru Kakegawa, Masayuki Itoh, Toma Adachi, Satoshi Miyashita, Yukiko U. Inoue, Kento Hizawa, Kei Hori, Natsumi Honjoya, Haruya Yagishita, Shinichiro Taya, Taisuke Miyazaki, Chika Usui, Shoji Tatsumoto, Akiko Tsuzuki, Hirotomo Uetake, Kazuhisa Sakai, Kazuhiro Yamakawa, Takuya Sasaki, Jun Nagai, Yoshiya Kawaguchi, Masaki Sone, Takayoshi Inoue, Yasuhiro Go, Noritaka Ichinohe, Kozo Kaibuchi, Masahiko Watanabe, Schuichi Koizumi, Michisuke Yuzaki, Mikio Hoshino
Nat Commun. 2024; 15: 458. Published online 2024 Feb 1. doi: 10.1038/s41467-023-44579-z
PMCID:
PMC10834496
AbstractArticlePDF–4.3M
4.
Brn3b regulates the formation of fear-related midbrain circuits and defensive responses to visual threat
Hyoseo Lee, Hannah Weinberg-Wolf, Hae-Lim Lee, Tracy Lee, Joseph Conte, Carlos Godoy-Parejo, Jonathan B. Demb, Andrii Rudenko, In-Jung Kim
PLoS Biol. 2023 Nov; 21(11): e3002386. Published online 2023 Nov 20. doi: 10.1371/journal.pbio.3002386
PMCID:
PMC10695396
AbstractArticlePDF–4.2M
5.
Prdm12 represses the expression of the visceral neuron determinants Phox2a/b in developing somatosensory ganglia
Simon Vermeiren, Pauline Cabochette, Maya Dannawi, Simon Desiderio, Alba Sabaté San José, Younes Achouri, Sadia Kricha, Maren Sitte, Gabriela Salinas-Riester, Benoit Vanhollebeke, Jean-François Brunet, Eric J. Bellefroid
iScience. 2023 Dec 15; 26(12): 108364. Published online 2023 Oct 31. doi: 10.1016/j.isci.2023.108364
PMCID:
PMC10663820
AbstractArticlePDF–5.8M
6.
Attenuated cerebellar phenotypes in Inpp4a truncation mutants with preserved phosphatase activity
Dang Minh Tran, Nozomu Yoshioka, Norihisa Bizen, Yukiko Mori-Ochiai, Masato Yano, Shogo Yanai, Junya Hasegawa, Satoshi Miyashita, Mikio Hoshino, Junko Sasaki, Takehiko Sasaki, Hirohide Takebayashi
Dis Model Mech. 2023 Jul 1; 16(7): dmm050169. Published online 2023 Jul 28. doi: 10.1242/dmm.050169
PMCID:
PMC10399444
AbstractArticle
7.
ENGRAILED‐1 transcription factor has a paracrine neurotrophic activity on adult spinal α‐motoneurons
Mélanie Lebœuf, Stephanie E Vargas‐Abonce, Eugénie Pezé‐Hedsieck, Edmond Dupont, Lucia Jimenez‐Alonso, Kenneth L Moya, Alain Prochiantz
EMBO Rep. 2023 Aug; 24(8): e56525. Published online 2023 Jul 6. doi: 10.15252/embr.202256525
PMCID:
PMC10398658
AbstractArticlePDF–6.3M
8.
The Midbrain Preisthmus: A Poorly Known Effect of the Isthmic Organizer
Luis Puelles, Matias Hidalgo-Sánchez
Int J Mol Sci. 2023 Jun; 24(11): 9769. Published online 2023 Jun 5. doi: 10.3390/ijms24119769
PMCID:
PMC10253667
AbstractArticlePDF–6.8M
9.
Disruption of the ATXN1-CIC complex reveals the role of additional nuclear ATXN1 interactors in spinocerebellar ataxia type 1
Stephanie L. Coffin, Mark A. Durham, Larissa Nitschke, Eder Xhako, Amanda M. Brown, Jean-Pierre Revelli, Esmeralda Villavicencio Gonzalez, Tao Lin, Hillary P. Handler, Yanwan Dai, Alexander J. Trostle, Ying-Wooi Wan, Zhandong Liu, Roy V. Sillitoe, Harry T. Orr, Huda Y. Zoghbi
Neuron. Author manuscript; available in PMC 2023 Feb 25.
Published in final edited form as: Neuron. 2023 Feb 15; 111(4): 481–492.e8. Published online 2022 Dec 27. doi: 10.1016/j.neuron.2022.11.016
Correction in:
Neuron. 2023 Mar 15; 111(6): 915.
PMCID:
PMC9957872
AbstractArticlePDF–1.7M
10.
Differential modularity of the mammalian Engrailed 1 enhancer network directs sweat gland development
Daniel Aldea, Blerina Kokalari, Yuji Atsuta, Heather L. Dingwall, Ying Zheng, Arben Nace, George Cotsarelis, Yana G. Kamberov
PLoS Genet. 2023 Feb; 19(2): e1010614. Published online 2023 Feb 6. doi: 10.1371/journal.pgen.1010614
PMCID:
PMC9934363
AbstractArticlePDF–1.9M
11.
Continuous cholinergic-dopaminergic updating in the nucleus accumbens underlies approaches to reward-predicting cues
Miguel Skirzewski, Oren Princz-Lebel, Liliana German-Castelan, Alycia M. Crooks, Gerard Kyungwook Kim, Sophie Henke Tarnow, Amy Reichelt, Sara Memar, Daniel Palmer, Yulong Li, R. Jane Rylett, Lisa M. Saksida, Vania F. Prado, Marco A. M. Prado, Timothy J. Bussey
Nat Commun. 2022; 13: 7924. Published online 2022 Dec 24. doi: 10.1038/s41467-022-35601-x
PMCID:
PMC9789106
AbstractArticlePDF–4.3M
12.
En1 and Lmx1b do not recapitulate embryonic dorsal-ventral limb patterning functions during mouse digit tip regeneration
Gemma L. Johnson, Morgan B. Glasser, Julia F. Charles, Jeffrey Duryea, Jessica A. Lehoczky
Cell Rep. Author manuscript; available in PMC 2022 Dec 7.
Published in final edited form as: Cell Rep. 2022 Nov 22; 41(8): 111701. doi: 10.1016/j.celrep.2022.111701
PMCID:
PMC9727699
AbstractArticlePDF–1.7M
13.
Embryo model completes gastrulation to neurulation and organogenesis
Gianluca Amadei, Charlotte E. Handford, Chengxiang Qiu, Joachim De Jonghe, Hannah Greenfeld, Martin Tran, Beth K. Martin, Dong-Yuan Chen, Alejandro Aguilera-Castrejon, Jacob H. Hanna, Michael B. Elowitz, Florian Hollfelder, Jay Shendure, David M. Glover, Magdalena Zernicka-Goetz
Nature. 2022; 610(7930): 143–153. Published online 2022 Aug 25. doi: 10.1038/s41586-022-05246-3
PMCID:
PMC9534772
AbstractArticlePDF–29M
14.
Transcriptional profiling reveals roles of intercellular Fgf9 signaling in astrocyte maturation and synaptic refinement during brainstem development
Ashley N. Brandebura, Douglas R. Kolson, Emily M. Amick, Jad Ramadan, Matthew C. Kersting, Robert H. Nichol, Paul S. Holcomb, Peter H. Mathers, Peter Stoilov, George A. Spirou
J Biol Chem. 2022 Aug; 298(8): 102176. Published online 2022 Jun 23. doi: 10.1016/j.jbc.2022.102176
PMCID:
PMC9304775
AbstractArticlePDF–5.5M
15.
Human midbrain dopaminergic neuronal differentiation markers predict cell therapy outcomes in a Parkinson’s disease model
Peibo Xu, Hui He, Qinqin Gao, Yingying Zhou, Ziyan Wu, Xiao Zhang, Linyu Sun, Gang Hu, Qian Guan, Zhiwen You, Xinyue Zhang, Wenping Zheng, Man Xiong, Yuejun Chen
J Clin Invest. 2022 Jul 15; 132(14): e156768. Published online 2022 Jul 15. doi: 10.1172/JCI156768
PMCID:
PMC9282930
AbstractArticlePDF–19M
16.
Mafa-dependent GABAergic activity promotes mouse neonatal apneas
Laure Lecoin, Bowen Dempsey, Alexandra Garancher, Steeve Bourane, Pierre-Louis Ruffault, Marie-Pierre Morin-Surun, Nathalie Rocques, Martyn Goulding, Alain Eychène, Celio Pouponnot, Gilles Fortin, Jean Champagnat
Nat Commun. 2022; 13: 3284. Published online 2022 Jun 7. doi: 10.1038/s41467-022-30825-3
PMCID:
PMC9174494
AbstractArticlePDF–3.2M
17.
Skin fibrosis and recovery is dependent on Wnt activation via DPP4
Anna R. Jussila, Brian Zhang, Elizabeth Caves, Sakin Kirti, Miarasa Steele, Emily Hamburg-Shields, John Lydon, Yan Ying, Robert Lafyatis, Sanjay Rajagopalan, Valerie Horsley, Radhika P. Atit
J Invest Dermatol. Author manuscript; available in PMC 2023 Jun 1.
Published in final edited form as: J Invest Dermatol. 2022 Jun; 142(6): 1597–1606.e9. Published online 2021 Nov 20. doi: 10.1016/j.jid.2021.10.025
PMCID:
PMC9120259
AbstractArticlePDF–2.3M
18.
Preventing Engrailed-1 activation in fibroblasts yields wound regeneration without scarring
Shamik Mascharak, Heather E. des Jardins-Park, Michael F. Davitt, Michelle Griffin, Mimi R. Borrelli, Alessandra L. Moore, Kellen Chen, Bryan Duoto, Malini Chinta, Deshka S. Foster, Abra H. Shen, Michael Januszyk, Sun Hyung Kwon, Gerlinde Wernig, Derrick C. Wan, H. Peter Lorenz, Geoffrey C. Gurtner, Michael T. Longaker
Science. Author manuscript; available in PMC 2022 Apr 14.
Published in final edited form as: Science. 2021 Apr 23; 372(6540): eaba2374. doi: 10.1126/science.aba2374
PMCID:
PMC9008875
AbstractArticlePDF–4.2M
19.
Multi-omic analysis reveals divergent molecular events in scarring and regenerative wound healing
Shamik Mascharak, Heather E. Talbott, Michael Januszyk, Michelle Griffin, Kellen Chen, Michael F. Davitt, Janos Demeter, Dominic Henn, Clark A. Bonham, Deshka S. Foster, Nancie Mooney, Ran Cheng, Peter K. Jackson, Derrick C. Wan, Geoffrey C. Gurtner, Michael T. Longaker
Cell Stem Cell. Author manuscript; available in PMC 2022 Apr 7.
Published in final edited form as: Cell Stem Cell. 2022 Feb 3; 29(2): 315–327.e6. Published online 2022 Jan 24. doi: 10.1016/j.stem.2021.12.011
PMCID:
PMC8988390
AbstractArticlePDF–3.9M
20.
Rnf220 is Implicated in the Dorsoventral Patterning of the Hindbrain Neural Tube in Mice
Yu-Bing Wang, Ning-Ning Song, Lei Zhang, Pengcheng Ma, Jia-Yin Chen, Ying Huang, Ling Hu, Bingyu Mao, Yu-Qiang Ding
Front Cell Dev Biol. 2022; 10: 831365. Published online 2022 Mar 24. doi: 10.3389/fcell.2022.831365
PMCID:
PMC8988044
AbstractArticlePDF–3.2M

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