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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 102333812.

Dosage sensitivity to Pumilio1 variants in the mouse brain reflects distinct molecular mechanisms

Salvatore Botta, Nicola de Prisco, Alexei Chemiakine, Vicky Brandt, Maximilian Cabaj, Purvi Patel, Ella Doron‐Mandel, Colton J Treadway, Marko Jovanovic, Nicholas G Brown, Rajesh K Soni, Vincenzo A Gennarino

EMBO J. 2023 Jun; 42(11): e112721. Published online 2023 Apr 18. doi: 10.15252/embj.2022112721

PMCID:: PMC10233381

Abstract Article PDF–26M

Select item 89565813.

PUMILIO proteins promote colorectal cancer growth via suppressing p21

Yuanyuan Gong, Zukai Liu, Yihang Yuan, Zhenzhen Yang, Jiawei Zhang, Qin Lu, Wei Wang, Chao Fang, Haifan Lin, Sanhong Liu

Nat Commun. 2022; 13: 1627. Published online 2022 Mar 25. doi: 10.1038/s41467-022-29309-1

PMCID:: PMC8956581

Abstract Article PDF–7.7M

Select item 74159914.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 71485645.

Pumilio proteins utilize distinct regulatory mechanisms to achieve complementary functions required for pluripotency and embryogenesis

Katherine E. Uyhazi, Yiying Yang, Na Liu, Hongying Qi, Xiao A. Huang, Winifred Mak, Scott D. Weatherbee, Nicola de Prisco, Vincenzo A. Gennarino, Xiaoling Song, Haifan Lin

Proc Natl Acad Sci U S A. 2020 Apr 7; 117(14): 7851–7862. Published online 2020 Mar 20. doi: 10.1073/pnas.1916471117

Correction in:: Proc Natl Acad Sci U S A. 2020 Apr 28; 117(17): 9643.

PMCID:: PMC7148564

Abstract Article PDF–2.9M

Select item 64449396.

Mammalian Pum1 and Pum2 Control Body Size via Translational Regulation of the Cell Cycle Inhibitor Cdkn1b

Kaibo Lin, Wenan Qiang, Mengyi Zhu, Yan Ding, Qinghua Shi, Xia Chen, Emese Zsiros, Kun Wang, Xiaodi Yang, Takeshi Kurita, Eugene Yujun Xu

Cell Rep. Author manuscript; available in PMC 2019 Apr 2.

Published in final edited form as: Cell Rep. 2019 Feb 26; 26(9): 2434–2450.e6. doi: 10.1016/j.celrep.2019.01.111

PMCID:: PMC6444939

Abstract Article PDF–2.9M

Select item 63299137.

Essential requirement of mammalian Pumilio family in embryonic development

Kaibo Lin, Shikun Zhang, Qinghua Shi, Mengyi Zhu, Liuze Gao, Wenjuan Xia, Baobao Geng, Zimeng Zheng, Eugene Yujun Xu

Mol Biol Cell. 2018 Nov 26; 29(24): 2922–2932. doi: 10.1091/mbc.E18-06-0369

PMCID:: PMC6329913

Abstract Article PDF–2.2M

Select item 61946048.

A role of Pumilio 1 in mammalian oocyte maturation and maternal phase of embryogenesis

Winifred Mak, Jing Xia, Ee-Chun Cheng, Katie Lowther, Haifan Lin

Cell Biosci. 2018; 8: 54. Published online 2018 Oct 19. doi: 10.1186/s13578-018-0251-1

PMCID:: PMC6194604

Abstract Article PDF–2.4M

Select item 58320589.

A mild PUM1 mutation is associated with adult-onset ataxia, whereas haploinsufficiency causes developmental delay and seizures

Vincenzo A. Gennarino, Elizabeth E. Palmer, Laura M. McDonell, Li Wang, Carolyn J. Adamski, Amanda Koire, Lauren See, Chun-An Chen, Christian P. Schaaf, Jill A. Rosenfeld, Jessica A. Panzer, Ute Moog, Shuang Hao, Ann Bye, Edwin P. Kirk, Pawel Stankiewicz, Amy M. Breman, Arran McBride, Tejaswi Kandula, Holly A. Dubbs, Rebecca Macintosh, Michael Cardamone, Ying Zhu, Kevin Ying, Kerith-Rae Dias, Megan T. Cho, Lindsay B. Henderson, Berivan Baskin, Paula Morris, Jiang Tao, Mark J. Cowley, Marcel E. Dinger, Tony Roscioli, Oana Caluseriu, Oksana Suchowersky, Rani K. Sachdev, Olivier Lichtarge, Jianrong Tang, Kym M. Boycott, J. Lloyd Holder, Jr., Huda Y. Zoghbi

Cell. Author manuscript; available in PMC 2019 Feb 22.

Published in final edited form as: Cell. 2018 Feb 22; 172(5): 924–936.e11. doi: 10.1016/j.cell.2018.02.006

PMCID:: PMC5832058

Abstract Article PDF–1.9M

Select item 562931210.

Do Gametes Woo? Evidence for Their Nonrandom Union at Fertilization

Joseph H. Nadeau

Genetics. 2017 Oct; 207(2): 369–387. Published online 2017 Sep 29. doi: 10.1534/genetics.117.300109

PMCID:: PMC5629312

Abstract Article PDF–957K

Select item 558065611.

Post-transcriptional regulation of mouse neurogenesis by Pumilio proteins

Meng Zhang, Dong Chen, Jing Xia, Wenqi Han, Xiekui Cui, Nils Neuenkirchen, Gretchen Hermes, Nenad Sestan, Haifan Lin

Genes Dev. 2017 Jul 1; 31(13): 1354–1369. doi: 10.1101/gad.298752.117

PMCID:: PMC5580656

Abstract Article PDF–695K

Select item 538122612.

Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function

Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang

Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626

PMCID:: PMC5381226

Abstract Article PDF–1.4M

Select item 494680513.

An Important Role of Pumilio 1 in Regulating the Development of the Mammalian Female Germline

Winifred Mak, Caodi Fang, Tobias Holden, Milana Bockhur Dratver, Haifan Lin

Biol Reprod. 2016 Jun; 94(6): 134. Published online 2016 May 11. doi: 10.1095/biolreprod.115.137497

PMCID:: PMC4946805

Abstract Article PDF–3.3M

Select item 471841414.

Dead end1 is an essential partner of NANOS2 for selective binding of target RNAs in male germ cell development

Atsushi Suzuki, Yuki Niimi, Kaori Shinmyozu, Zhi Zhou, Makoto Kiso, Yumiko Saga

EMBO Rep. 2016 Jan; 17(1): 37–46. Published online 2015 Nov 20. doi: 10.15252/embr.201540828

PMCID:: PMC4718414

Abstract Article PDF–2.0M

Select item 438304615.

Pumilio1 Haploinsufficiency Leads to SCA1-like Neurodegeneration by Increasing Wild-Type Ataxin1 Levels

Vincenzo A. Gennarino, Ravi K. Singh, Joshua J. White, Antonia De Maio, Kihoon Han, Ji-Yoen Kim, Paymaan Jafar-Nejad, Alberto di Ronza, Hyojin Kang, Layal S. Sayegh, Thomas A. Cooper, Harry T. Orr, Roy V. Sillitoe, Huda Y. Zoghbi

Cell. Author manuscript; available in PMC 2016 Mar 12.

Published in final edited form as: Cell. 2015 Mar 12; 160(6): 1087–1098. doi: 10.1016/j.cell.2015.02.012