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Select item 109062171.

Glycolysis-Mediated Activation of v-ATPase by Nicotinamide Mononucleotide Ameliorates Lipid-Induced Cardiomyopathy by Repressing the CD36-TLR4 Axis

Shujin Wang, Yinying Han, Ruimin Liu, Mengqian Hou, Dietbert Neumann, Jun Zhang, Fang Wang, Yumeng Li, Xueya Zhao, Francesco Schianchi, Chao Dai, Lizhong Liu, Miranda Nabben, Jan F.C. Glatz, Xin Wu, Xifeng Lu, Xi Li, Joost J.F.P. Luiken

Circ Res. 2024 Mar 1; 134(5): 505–525. Published online 2024 Feb 7. doi: 10.1161/CIRCRESAHA.123.322910

PMCID:: PMC10906217

Abstract Article PDF–15M

Select item 108645492.

Upregulation of ATP6V0D2 benefits intracellular survival of Leishmania donovani in erythrocytes-engulfing macrophages

Jing Hong, Budhaditya Mukherjee, Chizu Sanjoba, Junya Yamagishi, Yasuyuki Goto

Front Cell Infect Microbiol. 2024; 14: 1332381. Published online 2024 Jan 31. doi: 10.3389/fcimb.2024.1332381

PMCID:: PMC10864549

Abstract Article PDF–1.4M

Select item 103710273.

Lysosomal dysfunction in Down syndrome and Alzheimer mouse models is caused by v-ATPase inhibition by Tyr⁶⁸²-phosphorylated APP βCTF

Eunju Im, Ying Jiang, Philip H. Stavrides, Sandipkumar Darji, Hediye Erdjument-Bromage, Thomas A. Neubert, Jun Yong Choi, Jerzy Wegiel, Ju-Hyun Lee, Ralph A. Nixon

Sci Adv. 2023 Jul; 9(30): eadg1925. Published online 2023 Jul 26. doi: 10.1126/sciadv.adg1925

PMCID:: PMC10371027

Abstract Article PDF–2.6M

Select item 96742174.

SOX9 and SOX10 control fluid homeostasis in the inner ear for hearing through independent and cooperative mechanisms

Irene Y. Y. Szeto, Daniel K. H. Chu, Peikai Chen, Ka Chi Chu, Tiffany Y. K. Au, Keith K. H. Leung, Yong-Heng Huang, Sarah L. Wynn, Angel C. Y. Mak, Ying-Shing Chan, Wood Yee Chan, Ralf Jauch, Bernd Fritzsch, Mai Har Sham, Robin Lovell-Badge, Kathryn S. E. Cheah

Proc Natl Acad Sci U S A. 2022 Nov 15; 119(46): e2122121119. Published online 2022 Nov 7. doi: 10.1073/pnas.2122121119

PMCID:: PMC9674217

Abstract Article PDF–2.7M

Select item 95397565.

Leishmania infection-induced multinucleated giant cell formation via upregulation of ATP6V0D2 expression

Jing Hong, Chizu Sanjoba, Wataru Fujii, Junya Yamagishi, Yasuyuki Goto

Front Cell Infect Microbiol. 2022; 12: 953785. Published online 2022 Sep 23. doi: 10.3389/fcimb.2022.953785

PMCID:: PMC9539756

Abstract Article PDF–10M

Select item 80240716.

Inhibiting ATP6V0D2 Aggravates Liver Ischemia-Reperfusion Injury by Promoting NLRP3 Activation via Impairing Autophagic Flux Independent of Notch1/Hes1

Ziyi Wang, Hao Wang, Xuejiao Chen, Sheng Han, Yulin Zhu, Hanhua Wang, Feng Cheng, Liyong Pu

J Immunol Res. 2021; 2021: 6670495. Published online 2021 Mar 29. doi: 10.1155/2021/6670495

PMCID:: PMC8024071

Abstract Article PDF–3.7M

Select item 69385007.

Innate immune responses through Toll-like receptor 3 require human-antigen-R-mediated Atp6v0d2 mRNA stabilization

Mohd Izwan Bin Zainol, Takumi Kawasaki, Warunthorn Monwan, Motoya Murase, Takuya Sueyoshi, Taro Kawai

Sci Rep. 2019; 9: 20406. Published online 2019 Dec 31. doi: 10.1038/s41598-019-56914-w

PMCID:: PMC6938500

Abstract Article PDF–2.8M

Select item 66555518.

WDFY4 is required for cross-presentation in response to viral and tumor antigens

Derek J. Theisen, Jesse T. Davidson, IV, Carlos G. Briseño, Marco Gargaro, Elvin J. Lauron, Qiuling Wang, Pritesh Desai, Vivek Durai, Prachi Bagadia, Joshua R. Brickner, Wandy L. Beatty, Herbert W. Virgin, William E. Gillanders, Nima Mosammaparast, Michael S. Diamond, L. David Sibley, Wayne Yokoyama, Robert D. Schreiber, Theresa L. Murphy, Kenneth M. Murphy

Science. Author manuscript; available in PMC 2019 Jul 24.

Published in final edited form as: Science. 2018 Nov 9; 362(6415): 694–699. doi: 10.1126/science.aat5030

PMCID:: PMC6655551

Abstract Article PDF–1020K

Select item 66265929.

ATP6V0d2 mediates leucine-induced mTORC1 activation and polarization of macrophages

Pingfei Li, Xiaofei Deng, Jing Luo, Yufei Chen, Guoyu Bi, Feili Gong, Zhengping Wei, Na Liu, Huabin Li, Arian Laurence, Xiang-Ping Yang

Protein Cell. 2019 Aug; 10(8): 615–619. Published online 2019 May 27. doi: 10.1007/s13238-019-0636-x

PMCID:: PMC6626592

Article PDF–868K

Select item 659465610.

ATP6V₀d2 controls Leishmania parasitophorous vacuole biogenesis via cholesterol homeostasis

Carina Carraro Pessoa, Luiza Campos Reis, Eduardo Milton Ramos-Sanchez, Cristina Mary Orikaza, Cristian Cortez, Erica Valadares de Castro Levatti, Ana Carolina Benites Badaró, Joyce Umbelino da Silva Yamamoto, Vânia D’Almeida, Hiro Goto, Renato Arruda Mortara, Fernando Real

PLoS Pathog. 2019 Jun; 15(6): e1007834. Published online 2019 Jun 14. doi: 10.1371/journal.ppat.1007834

PMCID:: PMC6594656

Abstract Article PDF–4.6M

Select item 652682711.

The macrophage-specific V-ATPase subunit ATP6V0D2 restricts inflammasome activation and bacterial infection by facilitating autophagosome-lysosome fusion

Yu Xia, Na Liu, Xiuxiu Xie, Guoyu Bi, Hongping Ba, Lin Li, Jinxia Zhang, Xiaofei Deng, Yao Yao, Zhaohui Tang, Binjiao Yin, Jing Wang, Kan Jiang, Zhuoya Li, Yongwon Choi, Feili Gong, Xiang Cheng, John J O’Shea, Jae Jin Chae, Arian Laurence, Xiang-Ping Yang

Autophagy. 2019; 15(6): 960–975. Published online 2019 Jan 29. doi: 10.1080/15548627.2019.1569916

PMCID:: PMC6526827

Abstract Article PDF–3.5M

Select item 635522612.

Lactate inhibits ATP6V0d2 expression in tumor-associated macrophages to promote HIF-2α–mediated tumor progression

Na Liu, Jing Luo, Dong Kuang, Sanpeng Xu, Yaqi Duan, Yu Xia, Zhengping Wei, Xiuxiu Xie, Bingjiao Yin, Fang Chen, Shunqun Luo, Huicheng Liu, Jing Wang, Kan Jiang, Feili Gong, Zhao-hui Tang, Xiang Cheng, Huabin Li, Zhuoya Li, Arian Laurence, Guoping Wang, Xiang-Ping Yang

J Clin Invest. 2019 Feb 1; 129(2): 631–646. Published online 2019 Jan 7. doi: 10.1172/JCI123027

PMCID:: PMC6355226

Abstract Article PDF–17M

Select item 580377113.

Acidification of uterine epithelium during embryo implantation in mice

Shuo Xiao, Rong Li, Ahmed E. El Zowalaty, Honglu Diao, Fei Zhao, Yongwon Choi, Xiaoqin Ye

Biol Reprod. 2017 Jan; 96(1): 232–243. Published online 2016 Dec 23. doi: 10.1095/biolreprod.116.144451

PMCID:: PMC5803771

Abstract Article PDF–1.6M

Select item 563478714.

Molecular architecture underlying fluid absorption by the developing inner ear

Keiji Honda, Sung Huhn Kim, Michael C Kelly, Joseph C Burns, Laura Constance, Xiangming Li, Fei Zhou, Michael Hoa, Matthew W Kelley, Philine Wangemann, Robert J Morell, Andrew J Griffith

eLife. 2017; 6: e26851. Published online 2017 Oct 10. doi: 10.7554/eLife.26851

PMCID:: PMC5634787

Abstract Article PDF–6.3M

Select item 561195515.

Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development

Elisabeth A. Rutledge, Jean-Denis Benazet, Andrew P. McMahon

Development. 2017 Sep 1; 144(17): 3177–3188. doi: 10.1242/dev.149112

PMCID:: PMC5611955

Abstract Article

Select item 535500016.

Bone pain induced by multiple myeloma is reduced by targeting V-ATPase and ASIC3

Masahiro Hiasa, Tatsuo Okui, Yohance M Allette, Matthew S Ripsch, Ge-Hong Sun-Wada, Hiroki Wakabayashi, G David Roodman, Fletcher A. White, Toshiyuki Yoneda

Cancer Res. Author manuscript; available in PMC 2017 Sep 15.

Published in final edited form as: Cancer Res. 2017 Mar 15; 77(6): 1283–1295. Published online 2017 Mar 2. doi: 10.1158/0008-5472.CAN-15-3545

PMCID:: PMC5355000

Abstract Article PDF–2.6M

Select item 493062017.

Extra-renal locations of the a4 subunit of H⁺ATPase

Zoe J. Golder, Fiona E. Karet Frankl

BMC Cell Biol. 2016; 17: 27. Published online 2016 Jul 2. doi: 10.1186/s12860-016-0106-8

PMCID:: PMC4930620

Abstract Article PDF–1.4M

Select item 491601918.

Parallel Mechanisms Suppress Cochlear Bone Remodeling to Protect Hearing

Emmanuel J. Jáuregui, Omar Akil, Claire Acevedo, Faith Hall-Glenn, Betty S. Tsai, Hrishikesh A. Bale, Ellen Liebenberg, Mary Beth Humphrey, Robert O. Ritchie, Lawrence R. Lustig, Tamara Alliston

Bone. Author manuscript; available in PMC 2017 Aug 1.

Published in final edited form as: Bone. 2016 Aug; 89: 7–15. Published online 2016 Apr 13. doi: 10.1016/j.bone.2016.04.010

PMCID:: PMC4916019

Abstract Article PDF–2.0M

Select item 471679519.

Bovine parathyroid hormone enhances osteoclast bone resorption by modulating V-ATPase through PTH1R

SHUANGXIN LIU, WEIPING ZHU, SIJIA LI, JIANCHAO MA, HUITAO ZHANG, ZHONGHE LI, LI ZHANG, BIN ZHANG, ZHUO LI, XINLING LIANG, WEI SHI

Int J Mol Med. 2016 Feb; 37(2): 284–292. Published online 2015 Dec 7. doi: 10.3892/ijmm.2015.2423

PMCID:: PMC4716795

Abstract Article PDF–1.2M

Select item 356974220.

Tmem64 modulates calcium signaling during RANKL-mediated osteoclast differentiation

Hyunsoo Kim, Taesoo Kim, Byung-Chul Jeong, Il-Taeg Cho, Daehee Han, Noriko Takegahara, Takako Negishi-Koga, Hiroshi Takayanagi, Jae Hee Lee, Jai-Yoon Sul, Vikram Prasad, Seoung-Hoon Lee, Yongwon Choi

Cell Metab. Author manuscript; available in PMC 2014 Feb 5.

Published in final edited form as: Cell Metab. 2013 Feb 5; 17(2): 249–260. doi: 10.1016/j.cmet.2013.01.002

PMCID:: PMC3569742

Abstract Article PDF–2.8M

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