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Select item 113624591.

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation

Lisa Kofler, Lorenz Grundmann, Magdalena Gerhalter, Michael Prattes, Juliane Merl-Pham, Gertrude Zisser, Irina Grishkovskaya, Victor-Valentin Hodirnau, Martin Vareka, Rolf Breinbauer, Stefanie M. Hauck, David Haselbach, Helmut Bergler

Nat Commun. 2024; 15: 7511. Published online 2024 Aug 29. doi: 10.1038/s41467-024-51754-3

PMCID:: PMC11362459

Abstract Article PDF–3.5M

Select item 112946052.

Receptor-mediated cargo hitchhiking on bulk autophagy

Eigo Takeda, Takahiro Isoda, Sachiko Hosokawa, Yu Oikawa, Shukun Hotta-Ren, Alexander I May, Yoshinori Ohsumi

EMBO J. 2024 Aug; 43(15): 3116–3140. Published online 2024 May 16. doi: 10.1038/s44318-024-00091-8

PMCID:: PMC11294605

Abstract Article PDF–5.6M

Select item 110241853.

The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis

Victor E. Cruz, Christine S. Weirich, Nagesh Peddada, Jan P. Erzberger

Nat Commun. 2024; 15: 3296. Published online 2024 Apr 17. doi: 10.1038/s41467-024-47616-7

PMCID:: PMC11024185

Abstract Article PDF–7.4M

Select item 108687274.

Adaptive preservation of orphan ribosomal proteins in chaperone-dispersed condensates

Asif Ali, Rania Garde, Olivia C. Schaffer, Jared A. M. Bard, Kabir Husain, Samantha Keyport Kik, Kathleen A. Davis, Sofia Luengo-Woods, Maya G. Igarashi, D. Allan Drummond, Allison H. Squires, David Pincus

Nat Cell Biol. Author manuscript; available in PMC 2024 Feb 15.

Published in final edited form as: Nat Cell Biol. 2023 Nov; 25(11): 1691–1703. Published online 2023 Oct 16. doi: 10.1038/s41556-023-01253-2

PMCID:: PMC10868727

Abstract Article PDF–7.0M

Select item 107988585.

Fast-evolving cofactors regulate the role of HEATR5 complexes in intra-Golgi trafficking

Lucas J. Marmorale, Huan Jin, Thomas G. Reidy, Brandon Palomino-Alonso, Christopher J. Zysnarski, Fatima Jordan-Javed, Sagar Lahiri, Mara C. Duncan

J Cell Biol. 2024 Mar 4; 223(3): e202309047. Published online 2024 Jan 19. doi: 10.1083/jcb.202309047

PMCID:: PMC10798858

Abstract Article PDF–6.4M

Select item 107001386.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 102333687.

A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Nir Cohen, Naama Aviram, Maya Schuldiner

EMBO J. 2023 Jun; 42(11): e113385. Published online 2023 Apr 19. doi: 10.15252/embj.2022113385

PMCID:: PMC10233368

Abstract Article PDF–1.2M

Select item 92098118.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 80919819.

Essential histone chaperones collaborate to regulate transcription and chromatin integrity

Olga Viktorovskaya, James Chuang, Dhawal Jain, Natalia I. Reim, Francheska López-Rivera, Magdalena Murawska, Dan Spatt, L. Stirling Churchman, Peter J. Park, Fred Winston

Genes Dev. 2021 May 1; 35(9-10): 698–712. doi: 10.1101/gad.348431.121

PMCID:: PMC8091981

Abstract Article PDF–6.4M

Select item 775804910.

Bud23 promotes the final disassembly of the small subunit Processome in Saccharomyces cerevisiae

Joshua J. Black, Richa Sardana, Ezzeddine W. Elmir, Arlen W. Johnson

PLoS Genet. 2020 Dec; 16(12): e1009215. Published online 2020 Dec 11. doi: 10.1371/journal.pgen.1009215

PMCID:: PMC7758049

Abstract Article PDF–4.9M

Select item 768298811.

The deubiquitylase Ubp15 couples transcription to mRNA export

Fanny Eyboulet, Célia Jeronimo, Jacques Côté, François Robert

eLife. 2020; 9: e61264. Published online 2020 Nov 23. doi: 10.7554/eLife.61264

PMCID:: PMC7682988

Abstract Article PDF–1.4M

Select item 766412212.

The Capture of a Disabled Proteasome Identifies Erg25 as a Substrate for Endoplasmic Reticulum Associated Degradation

Teresa M. Buck, Xuemei Zeng, Pamela S. Cantrell, Richard T. Cattley, Zikri Hasanbasri, Megan E. Yates, Diep Nguyen, Nathan A. Yates, Jeffrey L. Brodsky

Mol Cell Proteomics. 2020 Nov; 19(11): 1896–1909. Published online 2020 Aug 31. doi: 10.1074/mcp.RA120.002050

PMCID:: PMC7664122

Abstract Article PDF–1.2M

Select item 738508413.

Coupling of 5S RNP rotation with maturation of functional centers during large ribosomal subunit assembly

Jelena Micic, Yu Li, Shan Wu, Daniel Wilson, Beril Tutuncuoglu, Ning Gao, John L. Woolford, Jr.

Nat Commun. 2020; 11: 3751. Published online 2020 Jul 27. doi: 10.1038/s41467-020-17534-5

PMCID:: PMC7385084

Abstract Article PDF–4.6M

Select item 727317714.

Chaperone-Mediated Protein Disaggregation Triggers Proteolytic Clearance of Intra-nuclear Protein Inclusions

Fabian den Brave, Lucas V. Cairo, Chandhuru Jagadeesan, Carmen Ruger-Herreros, Axel Mogk, Bernd Bukau, Stefan Jentsch

Cell Rep. 2020 Jun 2; 31(9): 107680. Published online 2020 Jun 2. doi: 10.1016/j.celrep.2020.107680

PMCID:: PMC7273177

Abstract Article

Select item 668908615.

The Hsp90 isoforms from S. cerevisiae differ in structure, function and client range

Hannah Girstmair, Franziska Tippel, Abraham Lopez, Katarzyna Tych, Frank Stein, Per Haberkant, Philipp Werner Norbert Schmid, Dominic Helm, Matthias Rief, Michael Sattler, Johannes Buchner

Nat Commun. 2019; 10: 3626. Published online 2019 Aug 9. doi: 10.1038/s41467-019-11518-w

PMCID:: PMC6689086

Abstract Article PDF–2.3M

Select item 664889516.

Tsr4 and Nap1, two novel members of the ribosomal protein chaperOME

Ingrid Rössler, Julia Embacher, Benjamin Pillet, Guillaume Murat, Laura Liesinger, Jutta Hafner, Julia Judith Unterluggauer, Ruth Birner-Gruenberger, Dieter Kressler, Brigitte Pertschy

Nucleic Acids Res. 2019 Jul 26; 47(13): 6984–7002. Published online 2019 May 7. doi: 10.1093/nar/gkz317

PMCID:: PMC6648895

Abstract Article PDF–14M

Select item 657951817.

Mechanism of completion of peptidyltransferase centre assembly in eukaryotes

Vasileios Kargas, Pablo Castro-Hartmann, Norberto Escudero-Urquijo, Kyle Dent, Christine Hilcenko, Carolin Sailer, Gertrude Zisser, Maria J Marques-Carvalho, Simone Pellegrino, Leszek Wawiórka, Stefan MV Freund, Jane L Wagstaff, Antonina Andreeva, Alexandre Faille, Edwin Chen, Florian Stengel, Helmut Bergler, Alan John Warren

eLife. 2019; 8: e44904. Published online 2019 May 22. doi: 10.7554/eLife.44904

PMCID:: PMC6579518

Abstract Article PDF–7.9M

Select item 634089618.

Cryo-EM structure of an early precursor of large ribosomal subunit reveals a half-assembled intermediate

Dejian Zhou, Xing Zhu, Sanduo Zheng, Dan Tan, Meng-Qiu Dong, Keqiong Ye

Protein Cell. 2019 Feb; 10(2): 120–130. Published online 2018 Mar 19. doi: 10.1007/s13238-018-0526-7

PMCID:: PMC6340896

Abstract Article PDF–2.8M

Select item 621627719.

A role for Mog1 in H2Bub1 and H3K4me3 regulation affecting RNAPII transcription and mRNA export

Paula Oliete‐Calvo, Joan Serrano‐Quílez, Carme Nuño‐Cabanes, María E Pérez‐Martínez, Luis M Soares, Bernhard Dichtl, Stephen Buratowski, José E Pérez‐Ortín, Susana Rodríguez‐Navarro

EMBO Rep. 2018 Nov; 19(11): e45992. Published online 2018 Sep 24. doi: 10.15252/embr.201845992