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Select item 113624591.

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation

Lisa Kofler, Lorenz Grundmann, Magdalena Gerhalter, Michael Prattes, Juliane Merl-Pham, Gertrude Zisser, Irina Grishkovskaya, Victor-Valentin Hodirnau, Martin Vareka, Rolf Breinbauer, Stefanie M. Hauck, David Haselbach, Helmut Bergler

Nat Commun. 2024; 15: 7511. Published online 2024 Aug 29. doi: 10.1038/s41467-024-51754-3

PMCID:: PMC11362459

Abstract Article PDF–3.5M

Select item 112945832.

Multi-signal regulation of the GSK-3β homolog Rim11 controls meiosis entry in budding yeast

Johanna Kociemba, Andreas Christ Sølvsten Jørgensen, Nika Tadić, Anthony Harris, Theodora Sideri, Wei Yee Chan, Fairouz Ibrahim, Elçin Ünal, Mark Skehel, Vahid Shahrezaei, Orlando Argüello-Miranda, Folkert Jacobus van Werven

EMBO J. 2024 Aug; 43(15): 3256–3286. Published online 2024 Jun 17. doi: 10.1038/s44318-024-00149-7

PMCID:: PMC11294583

Abstract Article PDF–5.1M

Select item 111394783.

Dual engagement of the nucleosomal acidic patches is essential for deposition of histone H2A.Z by SWR1C

Alexander S Baier, Nathan Gioacchini, Priit Eek, Erik M Leith, Song Tan, Craig L Peterson

eLife. 2024; 13: RP94869. Published online 2024 May 29. doi: 10.7554/eLife.94869

PMCID:: PMC11139478

Abstract Article PDF–3.6M

Select item 110241854.

The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis

Victor E. Cruz, Christine S. Weirich, Nagesh Peddada, Jan P. Erzberger

Nat Commun. 2024; 15: 3296. Published online 2024 Apr 17. doi: 10.1038/s41467-024-47616-7

PMCID:: PMC11024185

Abstract Article PDF–7.4M

Select item 108724775.

Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle

Michael J. O’Brien, Athar Ansari

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968

PMCID:: PMC10872477

Abstract Article PDF–1.7M

Select item 107988586.

Fast-evolving cofactors regulate the role of HEATR5 complexes in intra-Golgi trafficking

Lucas J. Marmorale, Huan Jin, Thomas G. Reidy, Brandon Palomino-Alonso, Christopher J. Zysnarski, Fatima Jordan-Javed, Sagar Lahiri, Mara C. Duncan

J Cell Biol. 2024 Mar 4; 223(3): e202309047. Published online 2024 Jan 19. doi: 10.1083/jcb.202309047

PMCID:: PMC10798858

Abstract Article PDF–6.4M

Select item 107001387.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 105509748.

Structure–function analysis of histone H2B and PCNA ubiquitination dynamics using deubiquitinase-deficient strains

Kaitlin S. Radmall, Prakash K. Shukla, Andrew M. Leng, Mahesh B. Chandrasekharan

Sci Rep. 2023; 13: 16731. Published online 2023 Oct 4. doi: 10.1038/s41598-023-43969-z

PMCID:: PMC10550974

Abstract Article PDF–1.7M

Select item 103819659.

Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere

Tom Dendooven, Ziguo Zhang, Jing Yang, Stephen H. McLaughlin, Johannes Schwab, Sjors H. W. Scheres, Stanislau Yatskevich, David Barford

Sci Adv. 2023 Jul; 9(30): eadg7480. Published online 2023 Jul 28. doi: 10.1126/sciadv.adg7480

PMCID:: PMC10381965

Abstract Article PDF–2.1M

Select item 1032590510.

The ribosome quality control factor Asc1 determines the fate of HSP70 mRNA on and off the ribosome

Lokha R Alagar Boopathy, Emma Beadle, Alan RuoChen Xiao, Aitana Garcia-Bueno Rico, Celia Alecki, Irene Garcia de-Andres, Kyla Edelmeier, Luca Lazzari, Mehdi Amiri, Maria Vera

Nucleic Acids Res. 2023 Jul 7; 51(12): 6370–6388. Published online 2023 May 9. doi: 10.1093/nar/gkad338

PMCID:: PMC10325905

Abstract Article PDF–2.9M

Select item 1028770611.

The histone H2B Arg95 residue efficiently recruits the transcription factor Spt16 to mediate Ste5 expression of the pheromone response pathway

Abdallah Alhaj Sulaiman, Reem Ali, Dindial Ramotar

Sci Rep. 2023; 13: 10189. Published online 2023 Jun 22. doi: 10.1038/s41598-023-37339-y

PMCID:: PMC10287706

Abstract Article PDF–1.9M

Select item 1023336812.

A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Nir Cohen, Naama Aviram, Maya Schuldiner

EMBO J. 2023 Jun; 42(11): e113385. Published online 2023 Apr 19. doi: 10.15252/embj.2022113385

PMCID:: PMC10233368

Abstract Article PDF–1.2M

Select item 1022661913.

The SAGA HAT module is tethered by its SWIRM domain and modulates activity of the SAGA DUB module

Sara T. Haile, Sanim Rahman, James K. Fields, Benjamin C. Orsburn, Namandjé N. Bumpus, Cynthia Wolberger

Biochim Biophys Acta Gene Regul Mech. Author manuscript; available in PMC 2023 Jun 1.

Published in final edited form as: Biochim Biophys Acta Gene Regul Mech. 2023 Jun; 1866(2): 194929. Published online 2023 Mar 24. doi: 10.1016/j.bbagrm.2023.194929

PMCID:: PMC10226619

Abstract Article PDF–1.8M

Select item 1021305014.

Bre1/RNF20 promotes Rad51-mediated strand exchange and antagonizes the Srs2/FBH1 helicases

Guangxue Liu, Jimin Li, Boxue He, Jiaqi Yan, Jingyu Zhao, Xuejie Wang, Xiaocong Zhao, Jingyan Xu, Yeyao Wu, Simin Zhang, Xiaoli Gan, Chun Zhou, Xiangpan Li, Xinghua Zhang, Xuefeng Chen

Nat Commun. 2023; 14: 3024. Published online 2023 May 25. doi: 10.1038/s41467-023-38617-z

PMCID:: PMC10213050

Abstract Article PDF–1.3M

Select item 1008580615.

Functional tug of war between kinases, phosphatases, and the Gcn5 acetyltransferase in chromatin and cell cycle checkpoint controls

Qihao Liu, Lorraine Pillus, Emily L Petty

G3 (Bethesda) 2023 Apr; 13(4): jkad021. Published online 2023 Feb 6. doi: 10.1093/g3journal/jkad021

PMCID:: PMC10085806

Abstract Article PDF–1003K

Select item 1008124616.

Mechanism of histone H2B monoubiquitination by Bre1

Fan Zhao, Chad W. Hicks, Cynthia Wolberger

Version 2. bioRxiv. Preprint. 2023 Mar 29 [revised 2023 Aug 28]. doi: 10.1101/2023.03.27.534461

Published in:: Nat Struct Mol Biol. 2023 Oct 23

PMCID:: PMC10081246

Abstract Article PDF–12M

Select item 1001834317.

Structure and functional determinants of Rad6–Bre1 subunits in the histone H2B ubiquitin-conjugating complex

Prakash K Shukla, Jesse E Bissell, Sanjit Kumar, Srijana Pokhrel, Sowmiya Palani, Kaitlin S Radmall, Onyeka Obidi, Timothy J Parnell, Julia Brasch, Dennis C Shrieve, Mahesh B Chandrasekharan

Nucleic Acids Res. 2023 Mar 21; 51(5): 2117–2136. Published online 2023 Jan 30. doi: 10.1093/nar/gkad012

PMCID:: PMC10018343

Abstract Article PDF–8.3M

Select item 935157018.

A hexasome is the preferred substrate for the INO80 chromatin remodeling complex, allowing versatility of function

Laura J. Hsieh, Muryam A. Gourdet, Camille M. Moore, Elise N. Muñoz, Nathan Gamarra, Vijay Ramani, Geeta J. Narlikar

Mol Cell. Author manuscript; available in PMC 2023 Jun 2.

Published in final edited form as: Mol Cell. 2022 Jun 2; 82(11): 2098–2112.e4. Published online 2022 May 20. doi: 10.1016/j.molcel.2022.04.026

PMCID:: PMC9351570

Abstract Article PDF–2.2M

Select item 920981119.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224