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Select item 98363481.

A synthetic genetic array screen for interactions with the RNA helicase DED1 during cell stress in budding yeast

Sara B Carey, Hannah M List, Ashwin Siby, Paolo Guerra, Timothy A Bolger

G3 (Bethesda) 2023 Jan; 13(1): jkac296. Published online 2022 Nov 21. doi: 10.1093/g3journal/jkac296

PMCID:: PMC9836348

Abstract Article PDF–857K

Select item 92098112.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 90408313.

Coexistence of Ammonium Transporter and Channel Mechanisms in Amt-Mep-Rh Twin-His Variants Impairs the Filamentation Signaling Capacity of Fungal Mep2 Transceptors

Gordon Williamson, Ana Sofia Brito, Adriana Bizior, Giulia Tamburrino, Gaëtan Dias Mirandela, Thomas Harris, Paul A. Hoskisson, Ulrich Zachariae, Anna Maria Marini, Mélanie Boeckstaens, Arnaud Javelle

mBio. 2022 Mar-Apr; 13(2): e02913-21. Published online 2022 Mar 1. doi: 10.1128/mbio.02913-21

PMCID:: PMC9040831

Abstract Article PDF–3.9M

Select item 84696924.

Regulation of Copper Metabolism by Nitrogen Utilization in Saccharomyces cerevisiae

Suzie Kang, Hyewon Seo, Min-Gyu Lee, Cheol-Won Yun

J Fungi (Basel) 2021 Sep; 7(9): 756. Published online 2021 Sep 14. doi: 10.3390/jof7090756

PMCID:: PMC8469692

Abstract Article PDF–1.3M

Select item 78508995.

Nutrient transceptors physically interact with the yeast S6/protein kinase B homolog, Sch9, a TOR kinase target

Zhiqiang Zhang, Ines Cottignie, Griet Van Zeebroeck, Johan M. Thevelein

Biochem J. 2021 Jan 29; 478(2): 357–375. Prepublished online 2021 Jan 4. Published online 2021 Jan 27. doi: 10.1042/BCJ20200722

PMCID:: PMC7850899

Abstract Article PDF–6.2M

Select item 77187516.

Comprehensive Synthetic Genetic Array Analysis of Alleles That Interact with Mutation of the Saccharomyces cerevisiae RecQ Helicases Hrq1 and Sgs1

Elsbeth Sanders, Phoebe A. Nguyen, Cody M. Rogers, Matthew L. Bochman

G3 (Bethesda) 2020 Dec; 10(12): 4359–4368. Published online 2020 Oct 28. doi: 10.1534/g3.120.401709

PMCID:: PMC7718751

Abstract Article PDF–1.2M

Select item 70483167.

Yeast filamentation signaling is connected to a specific substrate translocation mechanism of the Mep2 transceptor

Ana Sofia Brito, Benjamin Neuhäuser, René Wintjens, Anna Maria Marini, Mélanie Boeckstaens

PLoS Genet. 2020 Feb; 16(2): e1008634. Published online 2020 Feb 18. doi: 10.1371/journal.pgen.1008634

PMCID:: PMC7048316

Abstract Article PDF–5.7M

Select item 61355478.

Nitrogen isotope signature evidences ammonium deprotonation as a common transport mechanism for the AMT-Mep-Rh protein superfamily

Idoia Ariz, Mélanie Boeckstaens, Catarina Gouveia, Ana Paula Martins, Emanuel Sanz-Luque, Emilio Fernández, Graça Soveral, Nicolaus von Wirén, Anna M. Marini, Pedro M. Aparicio-Tejo, Cristina Cruz

Sci Adv. 2018 Sep; 4(9): eaar3599. Published online 2018 Sep 12. doi: 10.1126/sciadv.aar3599

PMCID:: PMC6135547

Abstract Article PDF–1.0M

Select item 59038639.

An incoherent feedforward loop facilitates adaptive tuning of gene expression

Jungeui Hong, Nathan Brandt, Farah Abdul-Rahman, Ally Yang, Tim Hughes, David Gresham

eLife. 2018; 7: e32323. Published online 2018 Apr 5. doi: 10.7554/eLife.32323

PMCID:: PMC5903863

Abstract Article PDF–2.4M

Select item 576535910.

Genome-Wide Mapping of Decay Factor–mRNA Interactions in Yeast Identifies Nutrient-Responsive Transcripts as Targets of the Deadenylase Ccr4

Jason E. Miller, Liye Zhang, Haoyang Jiang, Yunfei Li, B. Franklin Pugh, Joseph C. Reese

G3 (Bethesda) 2018 Jan; 8(1): 315–330. Published online 2017 Nov 20. doi: 10.1534/g3.117.300415

PMCID:: PMC5765359

Abstract Article PDF–2.2M

Select item 566188511.

A global interaction network maps a wiring diagram of cellular function

Michael Costanzo, Benjamin VanderSluis, Elizabeth N. Koch, Anastasia Baryshnikova, Carles Pons, Guihong Tan, Wen Wang, Matej Usaj, Julia Hanchard, Susan D. Lee, Vicent Pelechano, Erin B. Styles, Maximilian Billmann, Jolanda van Leeuwen, Nydia van Dyk, Zhen-Yuan Lin, Elena Kuzmin, Justin Nelson, Jeff S. Piotrowski, Tharan Srikumar, Sondra Bahr, Yiqun Chen, Raamesh Deshpande, Christoph F. Kurat, Sheena C. Li, Zhijian Li, Mojca Mattiazzi Usaj, Hiroki Okada, Natasha Pascoe, Bryan-Joseph San Luis, Sara Sharifpoor, Emira Shuteriqi, Scott W. Simpkins, Jamie Snider, Harsha Garadi Suresh, Yizhao Tan, Hongwei Zhu, Noel Malod-Dognin, Vuk Janjic, Natasa Przulj, Olga G. Troyanskaya, Igor Stagljar, Tian Xia, Yoshikazu Ohya, Anne-Claude Gingras, Brian Raught, Michael Boutros, Lars M. Steinmetz, Claire L. Moore, Adam P. Rosebrock, Amy A. Caudy, Chad L. Myers, Brenda Andrews, Charles Boone

Science. Author manuscript; available in PMC 2017 Oct 30.

Published in final edited form as: Science. 2016 Sep 23; 353(6306): aaf1420. doi: 10.1126/science.aaf1420

PMCID:: PMC5661885

Abstract Article PDF–2.6M

Select item 560025412.

The Genetic Landscape of a Cell

Michael Costanzo, Anastasia Baryshnikova, Jeremy Bellay, Yungil Kim, Eric D. Spear, Carolyn S. Sevier, Huiming Ding, Judice L.Y. Koh, Kiana Toufighi, Sara Mostafavi, Jeany Prinz, Robert P. St. Onge, Benjamin VanderSluis, Taras Makhnevych, Franco J. Vizeacoumar, Solmaz Alizadeh, Sondra Bahr, Renee L. Brost, Yiqun Chen, Murat Cokol, Raamesh Deshpande, Zhijian Li, Zhen-Yuan Lin, Wendy Liang, Michaela Marback, Jadine Paw, Bryan-Joseph San Luis, Ermira Shuteriqi, Amy Hin Yan Tong, Nydia van Dyk, Iain M. Wallace, Joseph A. Whitney, Matthew T. Weirauch, Guoqing Zhong, Hongwei Zhu, Walid A. Houry, Michael Brudno, Sasan Ragibizadeh, Balázs Papp, Csaba Pál, Frederick P. Roth, Guri Giaever, Corey Nislow, Olga G. Troyanskaya, Howard Bussey, Gary D. Bader, Anne-Claude Gingras, Quaid D. Morris, Philip M. Kim, Chris A. Kaiser, Chad L. Myers, Brenda J. Andrews, Charles Boone

Science. Author manuscript; available in PMC 2017 Sep 15.

Published in final edited form as: Science. 2010 Jan 22; 327(5964): 425–431. doi: 10.1126/science.1180823

PMCID:: PMC5600254

Abstract Article PDF–2.4M

Select item 486274013.

A comprehensive analysis of replicative lifespan in 4,698 single-gene deletion strains uncovers conserved mechanisms of aging

Mark A. McCormick, Joe R. Delaney, Mitsuhiro Tsuchiya, Scott Tsuchiyama, Anna Shemorry, Sylvia Sim, Annie Chia-Zong Chou, Umema Ahmed, Daniel Carr, Christopher J. Murakami, Jennifer Schleit, George L. Sutphin, Brian M. Wasko, Christopher F. Bennett, Adrienne M. Wang, Brady Olsen, Richard P. Beyer, Theodor K. Bammler, Donna Prunkard, Simon C. Johnson, Juniper K. Pennypacker, Elroy An, Arieanna Anies, Anthony S. Castanza, Eunice Choi, Nick Dang, Shiena Enerio, Marissa Fletcher, Lindsay Fox, Sarani Goswami, Sean A. Higgins, Molly A. Holmberg, Di Hu, Jessica Hui, Monika Jelic, Ki-Soo Jeong, Elijah Johnston, Emily O. Kerr, Jin Kim, Diana Kim, Katie Kirkland, Shannon Klum, Soumya Kotireddy, Eric Liao, Michael Lim, Michael S. Lin, Winston C. Lo, Dan Lockshon, Hillary A. Miller, Richard M. Moller, Brian Muller, Jonathan Oakes, Diana N. Pak, Zhao Jun Peng, Kim M. Pham, Tom G. Pollard, Prarthana Pradeep, Dillon Pruett, Dilreet Rai, Brett Robison, Ariana A. Rodriguez, Bopharoth Ros, Michael Sage, Manpreet K. Singh, Erica D. Smith, Katie Snead, Amrita Solanky, Benjamin L. Spector, Kristan K. Steffen, Bie Nga Tchao, Marc K. Ting, Helen Vander Wende, Dennis Wang, K. Linnea Welton, Eric A. Westman, Rachel B. Brem, Xin-guang Liu, Yousin Suh, Zhongjun Zhou, Matt Kaeberlein, Brian K. Kennedy

Cell Metab. Author manuscript; available in PMC 2016 Nov 3.

Published in final edited form as: Cell Metab. 2015 Nov 3; 22(5): 895–906. Published online 2015 Oct 8. doi: 10.1016/j.cmet.2015.09.008

PMCID:: PMC4862740

Abstract Article PDF–1.6M

Select item 485259814.

Structural basis for Mep2 ammonium transceptor activation by phosphorylation

Bert van den Berg, Anupama Chembath, Damien Jefferies, Arnaud Basle, Syma Khalid, Julian C. Rutherford

Nat Commun. 2016; 7: 11337. Published online 2016 Apr 18. doi: 10.1038/ncomms11337

PMCID:: PMC4852598

Abstract Article PDF–1.8M

Select item 450175015.

Identification of a Novel Regulatory Mechanism of Nutrient Transport Controlled by TORC1-Npr1-Amu1/Par32

Mélanie Boeckstaens, Ahmad Merhi, Elisa Llinares, Pascale Van Vooren, Jean-Yves Springael, René Wintjens, Anna Maria Marini

PLoS Genet. 2015 Jul; 11(7): e1005382. Published online 2015 Jul 14. doi: 10.1371/journal.pgen.1005382

PMCID:: PMC4501750

Abstract Article PDF–7.9M

Select item 438445916.

Ammonia Regulates VID30 Expression and Vid30p Function Shifts Nitrogen Metabolism toward Glutamate Formation Especially when Saccharomyces cerevisiae Is Grown in Low Concentrations of Ammonia

George K. van der Merwe, Terrance G. Cooper, Hennie J. J. van Vuuren

J Biol Chem. Author manuscript; available in PMC 2015 Apr 3.

Published in final edited form as: J Biol Chem. 2001 Aug 3; 276(31): 28659–28666. Published online 2001 May 16. doi: 10.1074/jbc.M102280200

PMCID:: PMC4384459

Abstract Article PDF–1.2M

Select item 388690317.

Molecular Specificity, Convergence and Constraint Shape Adaptive Evolution in Nutrient-Poor Environments

Jungeui Hong, David Gresham

PLoS Genet. 2014 Jan; 10(1): e1004041. Published online 2014 Jan 9. doi: 10.1371/journal.pgen.1004041

PMCID:: PMC3886903

Abstract Article PDF–1.1M

Select item 379073718.

Saccharomyces cerevisiae–Based Platform for Rapid Production and Evaluation of Eukaryotic Nutrient Transporters and Transceptors for Biochemical Studies and Crystallography

Peter Scharff-Poulsen, Per Amstrup Pedersen

PLoS One. 2013; 8(10): e76851. Published online 2013 Oct 4. doi: 10.1371/journal.pone.0076851

PMCID:: PMC3790737

Abstract Article PDF–1.7M

Select item 374276219.

SNPs Altering Ammonium Transport Activity of Human Rhesus Factors Characterized by a Yeast-Based Functional Assay

Aude Deschuyteneer, Mélanie Boeckstaens, Christelle De Mees, Pascale Van Vooren, René Wintjens, Anna Maria Marini

PLoS One. 2013; 8(8): e71092. Published online 2013 Aug 13. doi: 10.1371/journal.pone.0071092

PMCID:: PMC3742762

Abstract Article PDF–6.5M

Select item 364705820.

Ammonium Transport Proteins with Changes in One of the Conserved Pore Histidines Have Different Performance in Ammonia and Methylamine Conduction

Jinan Wang, Tim Fulford, Qiang Shao, Arnaud Javelle, Huaiyu Yang, Weiliang Zhu, Mike Merrick

PLoS One. 2013; 8(5): e62745. Published online 2013 May 7. doi: 10.1371/journal.pone.0062745

PMCID:: PMC3647058

Abstract Article PDF–2.7M

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