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Select item 108724771.

Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle

Michael J. O’Brien, Athar Ansari

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968

PMCID:: PMC10872477

Abstract Article PDF–1.7M

Select item 107001382.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 102977003.

The Hsp90 molecular chaperone governs client proteins by targeting intrinsically disordered regions

Janhavi A. Kolhe, Neethu L. Babu, Brian C. Freeman

Mol Cell. Author manuscript; available in PMC 2024 Jun 15.

Published in final edited form as: Mol Cell. 2023 Jun 15; 83(12): 2035–2044.e7. Published online 2023 Jun 8. doi: 10.1016/j.molcel.2023.05.021

PMCID:: PMC10297700

Abstract Article PDF–2.0M

Select item 98363484.

A synthetic genetic array screen for interactions with the RNA helicase DED1 during cell stress in budding yeast

Sara B Carey, Hannah M List, Ashwin Siby, Paolo Guerra, Timothy A Bolger

G3 (Bethesda) 2023 Jan; 13(1): jkac296. Published online 2022 Nov 21. doi: 10.1093/g3journal/jkac296

PMCID:: PMC9836348

Abstract Article PDF–857K

Select item 96380285.

Yeast Smy2 and its human homologs GIGYF1 and -2 regulate Cdc48/VCP function during transcription stress

Michelle Harreman Lehner, Jane Walker, Kotryna Temcinaite, Anna Herlihy, Michael Taschner, Adam C. Berger, Anita H. Corbett, A. Barbara Dirac Svejstrup, Jesper Q. Svejstrup

Cell Rep. 2022 Oct 25; 41(4): 111536. Published online 2022 Oct 25. doi: 10.1016/j.celrep.2022.111536

PMCID:: PMC9638028

Abstract Article

Select item 92860236.

Mediator recruits the cohesin loader Scc2 to RNA Pol II-transcribed genes and promotes sister chromatid cohesion

Mark Mattingly, Chris Seidel, Sofía Muñoz, Yan Hao, Ying Zhang, Zhihui Wen, Laurence Florens, Frank Uhlmann, Jennifer L. Gerton

Curr Biol. 2022 Jul 11; 32(13): 2884–2896.e6. doi: 10.1016/j.cub.2022.05.019

PMCID:: PMC9286023

Abstract Article

Select item 92098117.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 81913328.

The Cdk8 kinase module regulates interaction of the mediator complex with RNA polymerase II

Sara Osman, Eusra Mohammad, Michael Lidschreiber, Alexandra Stuetzer, Fanni Laura Bazsó, Kerstin C. Maier, Henning Urlaub, Patrick Cramer

J Biol Chem. 2021 Jan-Jun; 296: 100734. Published online 2021 Apr 30. doi: 10.1016/j.jbc.2021.100734

PMCID:: PMC8191332

Abstract Article PDF–2.6M

Select item 78103849.

Structure and noncanonical Cdk8 activation mechanism within an Argonaute-containing Mediator kinase module

Yi-Chuan Li, Ti-Chun Chao, Hee Jong Kim, Timothy Cholko, Shin-Fu Chen, Guojie Li, Laura Snyder, Kotaro Nakanishi, Chia-en Chang, Kenji Murakami, Benjamin A. Garcia, Thomas G. Boyer, Kuang-Lei Tsai

Sci Adv. 2021 Jan; 7(3): eabd4484. Published online 2021 Jan 15. doi: 10.1126/sciadv.abd4484

PMCID:: PMC7810384

Abstract Article PDF–4.3M

Select item 766412210.

The Capture of a Disabled Proteasome Identifies Erg25 as a Substrate for Endoplasmic Reticulum Associated Degradation

Teresa M. Buck, Xuemei Zeng, Pamela S. Cantrell, Richard T. Cattley, Zikri Hasanbasri, Megan E. Yates, Diep Nguyen, Nathan A. Yates, Jeffrey L. Brodsky

Mol Cell Proteomics. 2020 Nov; 19(11): 1896–1909. Published online 2020 Aug 31. doi: 10.1074/mcp.RA120.002050

PMCID:: PMC7664122

Abstract Article PDF–1.2M

Select item 750740211.

Systematic analysis of bypass suppression of essential genes

Jolanda van Leeuwen, Carles Pons, Guihong Tan, Zi Yang Wang, Jing Hou, Jochen Weile, Marinella Gebbia, Wendy Liang, Ermira Shuteriqi, Zhijian Li, Maykel Lopes, Matej Ušaj, Andreia Dos Santos Lopes, Natascha van Lieshout, Chad L Myers, Frederick P Roth, Patrick Aloy, Brenda J Andrews, Charles Boone

Mol Syst Biol. 2020 Sep; 16(9): e9828. Published online 2020 Sep 17. doi: 10.15252/msb.20209828

PMCID:: PMC7507402

Abstract Article PDF–1.9M

Select item 666992212.

Endosome and Golgi‐associated degradation (EGAD) of membrane proteins regulates sphingolipid metabolism

Oliver Schmidt, Yannick Weyer, Verena Baumann, Michael A Widerin, Sebastian Eising, Mihaela Angelova, Alexander Schleiffer, Leopold Kremser, Herbert Lindner, Matthias Peter, Florian Fröhlich, David Teis

EMBO J. 2019 Aug 1; 38(15): e101433. Published online 2019 May 27. doi: 10.15252/embj.2018101433

PMCID:: PMC6669922

Abstract Article PDF–2.8M

Select item 576535913.

Genome-Wide Mapping of Decay Factor–mRNA Interactions in Yeast Identifies Nutrient-Responsive Transcripts as Targets of the Deadenylase Ccr4

Jason E. Miller, Liye Zhang, Haoyang Jiang, Yunfei Li, B. Franklin Pugh, Joseph C. Reese

G3 (Bethesda) 2018 Jan; 8(1): 315–330. Published online 2017 Nov 20. doi: 10.1534/g3.117.300415

PMCID:: PMC5765359

Abstract Article PDF–2.2M

Select item 505508314.

Functional Metabolomics Describes the Yeast Biosynthetic Regulome

Michael Mülleder, Enrica Calvani, Mohammad Tauqeer Alam, Richard Kangda Wang, Florian Eckerstorfer, Aleksej Zelezniak, Markus Ralser

Cell. 2016 Oct 6; 167(2): 553–565.e12. doi: 10.1016/j.cell.2016.09.007

PMCID:: PMC5055083

Abstract Article PDF–3.9M

Select item 493606215.

Evidence for Multiple Mediator Complexes in Yeast Independently Recruited by Activated Heat Shock Factor

Jayamani Anandhakumar, Yara W. Moustafa, Surabhi Chowdhary, Amoldeep S. Kainth, David S. Gross

Mol Cell Biol. 2016 Jul 15; 36(14): 1943–1960. Prepublished online 2016 May 16. Published online 2016 Jun 29. doi: 10.1128/MCB.00005-16

PMCID:: PMC4936062

Abstract Article PDF–3.9M

Select item 487539816.

Structural flexibility and functional interaction of mediator Cdk8 module

Xuejuan Wang, Jianye Wang, Zhenrui Ding, Jinhua Ji, Qianqian Sun, Gang Cai

Protein Cell. 2013 Dec; 4(12): 911–920. Published online 2013 Sep 16. doi: 10.1007/s13238-013-3069-y

PMCID:: PMC4875398

Abstract Article PDF–2.0M

Select item 464423517.

The Nuclear Pore-Associated TREX-2 Complex Employs Mediator to Regulate Gene Expression

Maren Schneider, Doris Hellerschmied, Tobias Schubert, Stefan Amlacher, Vinesh Vinayachandran, Rohit Reja, B. Franklin Pugh, Tim Clausen, Alwin Köhler

Cell. 2015 Aug 27; 162(5): 1016–1028. doi: 10.1016/j.cell.2015.07.059

PMCID:: PMC4644235

Abstract Article

Select item 462706618.

Mediator independently orchestrates multiple steps of preinitiation complex assembly in vivo

Fanny Eyboulet, Sandra Wydau-Dematteis, Thomas Eychenne, Olivier Alibert, Helen Neil, Claire Boschiero, Marie-Claire Nevers, Hervé Volland, David Cornu, Virginie Redeker, Michel Werner, Julie Soutourina

Nucleic Acids Res. 2015 Oct 30; 43(19): 9214–9231. Published online 2015 Aug 3. doi: 10.1093/nar/gkv782

PMCID:: PMC4627066

Abstract Article PDF–594K

Select item 453851119.

Identification and Characterization of a Novel Family of Selective Antifungal Compounds (CANBEFs) That Interfere with Fungal Protein Synthesis

Gabriel Mircus, Nathaniel Albert, Dafna Ben-Yaakov, Dodo Chikvashvili, Yona Shadkchan, Dimitrios P. Kontoyiannis, Nir Osherov

Antimicrob Agents Chemother. 2015 Sep; 59(9): 5631–5640. Prepublished online 2015 Jul 6. Published online 2015 Aug 14. doi: 10.1128/AAC.00850-15

PMCID:: PMC4538511

Abstract Article PDF–686K

Select item 443181020.

The 4E-BP Caf20p Mediates Both eIF4E-Dependent and Independent Repression of Translation

Lydia M. Castelli, David Talavera, Christopher J. Kershaw, Sarah S. Mohammad-Qureshi, Joseph L. Costello, William Rowe, Paul F. G. Sims, Christopher M. Grant, Simon J. Hubbard, Mark P. Ashe, Graham D. Pavitt

PLoS Genet. 2015 May; 11(5): e1005233. Published online 2015 May 14. doi: 10.1371/journal.pgen.1005233