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Items: 1 to 20 of 424

1.
RUNX1/EVI1, which blocks myeloid differentiation, inhibits CCAAT–enhancer binding protein α function
Katsuya Tokita, Kazuhiro Maki, Kinuko Mitani
Cancer Sci. 2007 Nov; 98(11): 1752–1757. Published online 2007 Aug 23. doi: 10.1111/j.1349-7006.2007.00597.x
PMCID:
PMC11158720
AbstractArticlePDF–197K
2.
RUNX1-induced upregulation of PTGS2 enhances cell growth, migration and invasion in colorectal cancer cells
Weiwei Zheng, Yingchang Guo, Aihemaiti Kahar, Junwei Bai, Qinhui Zhu, Xinli Huang, Yuan Li, Bingyi Xu, Xueshan Jia, Gang Wu, Chao Zhang, Yuanzeng Zhu
Sci Rep. 2024; 14: 11670. Published online 2024 May 22. doi: 10.1038/s41598-024-60296-z
PMCID:
PMC11111780
AbstractArticlePDF–6.6M
3.
The role of RUNX1/NF-κB in regulating PVAT inflammation in aortic dissection
Ao Wang, Shengjun Dong, Baohui Liu, Dianxiao Liu, Mingrui Zou, Yuexin Han, Lijuan Yang, Yujiu Wang
Sci Rep. 2024; 14: 9960. Published online 2024 Apr 30. doi: 10.1038/s41598-024-60737-9
PMCID:
PMC11063189
AbstractArticlePDF–4.8M
4.
RUNX1-BMP2 promotes vasculogenic mimicry in laryngeal squamous cell carcinoma via activation of the PI3K-AKT signaling pathway
Qingwen Zhu, Xinyu Zhang, Fei Lu, Siyu Miao, Chunyang Zhang, Zhenzhen Liu, Zejun Gao, Meihao Qi, Xiaogang An, Panling Geng, Sufang Wang, Hongbo Ren, Fugen Han, Ruyue Zhang, DingJun Zha
Cell Commun Signal. 2024; 22: 227. Published online 2024 Apr 12. doi: 10.1186/s12964-024-01605-x
PMCID:
PMC11010429
AbstractArticlePDF–8.2M
5.
RUNX1 mutations mitigate quiescence to promote transformation of hematopoietic progenitors in Fanconi anemia
William Marion, Tiago Koppe, Chun-Chin Chen, Dahai Wang, Katie Frenis, Sara Fierstein, Prerana Sensharma, Olivia Aumais, Michael Peters, Sonya Ruiz-Torres, Tafadzwa Chihanga, Steffen Boettcher, Akiko Shimamura, Daniel E. Bauer, Thorsten Schlaeger, Susanne I. Wells, Benjamin L. Ebert, Daniel Starczynowski, Edroaldo Lummertz da Rocha, R. Grant Rowe
Leukemia. Author manuscript; available in PMC 2024 Jun 1.
Published in final edited form as: Leukemia. 2023 Aug; 37(8): 1698–1708. Published online 2023 Jun 30. doi: 10.1038/s41375-023-01945-6
PMCID:
PMC11009868
AbstractArticlePDF–1.0M
6.
Altered platelet-megakaryocyte endocytosis and trafficking of albumin and fibrinogen in RUNX1 haplodeficiency
Fabiola Del Carpio-Cano, Guangfen Mao, Lawrence E. Goldfinger, Jeremy Wurtzel, Liying Guan, Mohammad Afaque Alam, Kiwon Lee, Mortimer Poncz, A. Koneti Rao
Blood Adv. 2024 Apr 9; 8(7): 1699–1714. Published online 2024 Feb 10. doi: 10.1182/bloodadvances.2023011098
PMCID:
PMC10997914
AbstractArticlePDF–4.8M
7.
Runt-related transcription factor-1 ameliorates bile acid–induced hepatic inflammation in cholestasis through JAK/STAT3 signaling
Liangjun Zhang, Qiong Pan, Lu Zhang, Haihan Xia, Junwei Liao, Xiaoxun Zhang, Nan Zhao, Qiaoling Xie, Min Liao, Ya Tan, Qiao Li, Jinfei Zhu, Ling Li, Shijun Fan, Jianwei Li, Chengcheng Zhang, Shi-Ying Cai, James L. Boyer, Jin Chai
Hepatology. Author manuscript; available in PMC 2024 Mar 8.
Published in final edited form as: Hepatology. 2023 Jun 1; 77(6): 1866–1881. Published online 2023 Jan 3. doi: 10.1097/HEP.0000000000000041
PMCID:
PMC10921919
AbstractArticlePDF–3.1M
8.
Genomic landscape of patients with germline RUNX1 variants and familial platelet disorder with myeloid malignancy
Kai Yu, Natalie Deuitch, Matthew Merguerian, Lea Cunningham, Joie Davis, Erica Bresciani, Jamie Diemer, Elizabeth Andrews, Alice Young, Frank Donovan, Raman Sood, Kathleen Craft, Shawn Chong, Settara Chandrasekharappa, Jim Mullikin, Paul P. Liu
Blood Adv. 2024 Jan 23; 8(2): 497–511. Published online 2023 Nov 29. doi: 10.1182/bloodadvances.2023011165
PMCID:
PMC10837196
AbstractArticlePDF–2.7M
9.
Hematopoietic Transcription Factor RUNX1 is Essential for Promoting Macrophage–Myofibroblast Transition in Non‐Small‐Cell Lung Carcinoma
Philip Chiu‐Tsun Tang, Max Kam‐Kwan Chan, Jeff Yat‐Fai Chung, Alex Siu‐Wing Chan, Dongmei Zhang, Chunjie Li, Kam‐Tong Leung, Calvin Sze‐Hang Ng, Yi Wu, Ka‐Fai To, Hui‐Yao Lan, Patrick Ming‐Kuen Tang
Adv Sci (Weinh) 2024 Jan; 11(1): 2302203. Published online 2023 Nov 15. doi: 10.1002/advs.202302203
PMCID:
PMC10767400
AbstractArticlePDF–27M
10.
MYCT1 inhibits hematopoiesis in diffuse large B-cell lymphoma by suppressing RUNX1 transcription
Ying Liang, Xin Wei, Peng-Jie Yue, He-Cheng Zhang, Zhen-Ning Li, Xiao-Xue Wang, Yuan-Yuan Sun, Wei-Neng Fu
Cell Mol Biol Lett. 2024; 29: 5. Published online 2024 Jan 3. doi: 10.1186/s11658-023-00522-0
PMCID:
PMC10763471
AbstractArticlePDF–3.0M
11.
RUNX1 knockdown induced apoptosis and impaired EMT in high-grade serous ovarian cancer cells
Yuanzhi Chen, Zhicheng He, Shuting Yang, Cheng Chen, Wenyong Xiong, YingYing He, Shubai Liu
J Transl Med. 2023; 21: 886. Published online 2023 Dec 6. doi: 10.1186/s12967-023-04762-8
PMCID:
PMC10702124
AbstractArticlePDF–4.3M
12.
Hereditary platelet disorders associated with germ line variants in RUNX1, ETV6, and ANKRD26
Claire C. Homan, Hamish S. Scott, Anna L. Brown
Blood. 2023 Mar 30; 141(13): 1533–1543. Published online 2023 Jan 13. doi: 10.1182/blood.2022017735
PMCID:
PMC10651873
AbstractArticle
13.
Somatic mutational landscape of hereditary hematopoietic malignancies caused by germline variants in RUNX1, GATA2, and DDX41
Claire C. Homan, Michael W. Drazer, Kai Yu, David M. Lawrence, Jinghua Feng, Luis Arriola-Martinez, Matthew J. Pozsgai, Kelsey E. McNeely, Thuong Ha, Parvathy Venugopal, Peer Arts, Sarah L. King-Smith, Jesse Cheah, Mark Armstrong, Paul Wang, Csaba Bödör, Alan B. Cantor, Mario Cazzola, Erin Degelman, Courtney D. DiNardo, Nicolas Duployez, Remi Favier, Stefan Fröhling, Ana Rio-Machin, Jeffery M. Klco, Alwin Krämer, Mineo Kurokawa, Joanne Lee, Luca Malcovati, Neil V. Morgan, Georges Natsoulis, Carolyn Owen, Keyur P. Patel, Claude Preudhomme, Hana Raslova, Hugh Rienhoff, Tim Ripperger, Rachael Schulte, Kiran Tawana, Elvira Velloso, Benedict Yan, Erika Kim, Raman Sood, NISC Comparative Sequencing Program, Amy P. Hsu, Steven M. Holland, Kerry Phillips, Nicola K. Poplawski, Milena Babic, Andrew H. Wei, Cecily Forsyth, Helen Mar Fan, Ian D. Lewis, Julian Cooney, Rachel Susman, Lucy C. Fox, Piers Blombery, Deepak Singhal, Devendra Hiwase, Belinda Phipson, Andreas W. Schreiber, Christopher N. Hahn, Hamish S. Scott, Paul Liu, Lucy A. Godley, Anna L. Brown
Blood Adv. 2023 Oct 24; 7(20): 6092–6107. Published online 2023 Jul 7. doi: 10.1182/bloodadvances.2023010045
PMCID:
PMC10582382
AbstractArticlePDF–1.6M
14.
Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates
Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert
Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644
PMCID:
PMC10565876
AbstractArticlePDF–3.7M
15.
RUN(X) out of blood: emerging RUNX1 functions beyond hematopoiesis and links to Down syndrome
Esteban J. Rozen, Christopher D. Ozeroff, Mary Ann Allen
Hum Genomics. 2023; 17: 83. Published online 2023 Sep 5. doi: 10.1186/s40246-023-00531-2
PMCID:
PMC10481493
AbstractArticlePDF–4.6M
16.
Runx1/3-driven adaptive endoplasmic reticulum stress pathways contribute to neurofibromagenesis
Youjin Na, Ashley Hall, Yanan Yu, Liang Hu, Kwangmin Choi, Jake A. Burgard, Sara Szabo, Gang Huang, Nancy Ratner, Jianqiang Wu
Oncogene. Author manuscript; available in PMC 2023 May 18.
Published in final edited form as: Oncogene. 2023 Mar; 42(13): 1038–1047. Published online 2023 Feb 9. doi: 10.1038/s41388-023-02620-x
PMCID:
PMC10194627
AbstractArticlePDF–1.8M
17.
RUNX1 Ameliorates Rheumatoid Arthritis Progression through Epigenetic Inhibition of LRRC15
Hao Ding, Xiaoliang Mei, Lintao Li, Peng Fang, Ting Guo, Jianning Zhao
Mol Cells. 2023 Apr 30; 46(4): 231–244. Published online 2023 Jan 10. doi: 10.14348/molcells.2023.2136
PMCID:
PMC10086557
AbstractArticlePDF–41M
18.
RUNX1 Upregulation Causes Mitochondrial Dysfunction via Regulating the PI3K-Akt Pathway in iPSC from Patients with Down Syndrome
Yanna Liu, Yuehua Zhang, Zhaorui Ren, Fanyi Zeng, Jingbin Yan
Mol Cells. 2023 Apr 30; 46(4): 219–230. Published online 2023 Feb 10. doi: 10.14348/molcells.2023.2095
PMCID:
PMC10086551
AbstractArticlePDF–136M
19.
USP10 deubiquitinates RUNX1 and promotes proneural-to-mesenchymal transition in glioblastoma
Wenjin Qiu, Zumu Xiao, Yushi Yang, Lishi Jiang, Shibin Song, Xiaolan Qi, Yimin Chen, Hua Yang, Jian Liu, Liangzhao Chu
Cell Death Dis. 2023 Mar; 14(3): 207. Published online 2023 Mar 22. doi: 10.1038/s41419-023-05734-y
PMCID:
PMC10033651
AbstractArticlePDF–4.4M
20.
RUNX1 isoform disequilibrium promotes the development of trisomy 21–associated myeloid leukemia
Sofia Gialesaki, Daniela Bräuer-Hartmann, Hasan Issa, Raj Bhayadia, Oriol Alejo-Valle, Lonneke Verboon, Anna-Lena Schmell, Stephanie Laszig, Enikő Regényi, Konstantin Schuschel, Maurice Labuhn, Michelle Ng, Robert Winkler, Christian Ihling, Andrea Sinz, Markus Glaß, Stefan Hüttelmaier, Sören Matzk, Lena Schmid, Farina Josepha Strüwe, Sofie-Katrin Kadel, Dirk Reinhardt, Marie-Laure Yaspo, Dirk Heckl, Jan-Henning Klusmann
Blood. 2023 Mar 9; 141(10): 1105–1118. Published online 2022 Dec 13. doi: 10.1182/blood.2022017619
PMCID:
PMC10023736
AbstractArticle

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