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Items: 1 to 20 of 39

1.
Characterization of the dimeric CMG/pre-initiation complex and its transition into DNA replication forks
Lu Liu, Yue Zhang, Jingjing Zhang, Jian-Hua Wang, Qinhong Cao, Zhen Li, Judith L. Campbell, Meng-Qiu Dong, Huiqiang Lou
Cell Mol Life Sci. 2020 Aug; 77(15): 3041–3058. Published online 2019 Nov 15. doi: 10.1007/s00018-019-03333-9
PMCID:
PMC11104849
AbstractArticlePDF–9.1M
2.
The social and structural architecture of the yeast protein interactome
André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann
Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5
PMCID:
PMC10700138
AbstractArticlePDF–20M
3.
Synergism between CMG helicase and leading strand DNA polymerase at replication fork
Zhichun Xu, Jianrong Feng, Daqi Yu, Yunjing Huo, Xiaohui Ma, Wai Hei Lam, Zheng Liu, Xiang David Li, Toyotaka Ishibashi, Shangyu Dang, Yuanliang Zhai
Nat Commun. 2023; 14: 5849. Published online 2023 Sep 20. doi: 10.1038/s41467-023-41506-0
PMCID:
PMC10511561
AbstractArticlePDF–5.3M
4.
New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources
Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry
Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224
PMCID:
PMC9209811
AbstractArticlePDF–818K
5.
CMG helicase disassembly is controlled by replication fork DNA, replisome components and a ubiquitin threshold
Tom D Deegan, Progya P Mukherjee, Ryo Fujisawa, Cristian Polo Rivera, Karim Labib
eLife. 2020; 9: e60371. Published online 2020 Aug 17. doi: 10.7554/eLife.60371
PMCID:
PMC7462611
AbstractArticlePDF–4.9M
6.
In Vitro Reconstitution Defines the Minimal Requirements for Cdc48-Dependent Disassembly of the CMG Helicase in Budding Yeast
Progya P. Mukherjee, Karim P.M. Labib
Cell Rep. 2019 Sep 10; 28(11): 2777–2783.e4. Published online 2019 Sep 10. doi: 10.1016/j.celrep.2019.08.026
PMCID:
PMC6899518
AbstractArticle
7.
Ctf4 organizes sister replisomes and Pol α into a replication factory
Zuanning Yuan, Roxana Georgescu, Ruda de Luna Almeida Santos, Daniel Zhang, Lin Bai, Nina Y Yao, Gongpu Zhao, Michael E O'Donnell, Huilin Li
eLife. 2019; 8: e47405. Published online 2019 Oct 7. doi: 10.7554/eLife.47405
PMCID:
PMC6800005
AbstractArticlePDF–7.0M
8.
Replication Fork Activation Is Enabled by a Single-Stranded DNA Gate in CMG Helicase
Michael R. Wasserman, Grant D. Schauer, Michael E. O’Donnell, Shixin Liu
Cell. Author manuscript; available in PMC 2020 Jul 25.
Published in final edited form as: Cell. 2019 Jul 25; 178(3): 600–611.e16. doi: 10.1016/j.cell.2019.06.032
PMCID:
PMC6705614
AbstractArticlePDF–1.6M
9.
Mcm10 has potent strand-annealing activity and limits translocase-mediated fork regression
Ryan Mayle, Lance Langston, Kelly R. Molloy, Dan Zhang, Brian T. Chait, Michael E. O’Donnell
Proc Natl Acad Sci U S A. 2019 Jan 15; 116(3): 798–803. Published online 2018 Dec 31. doi: 10.1073/pnas.1819107116
PMCID:
PMC6338834
AbstractArticlePDF–1.3M
10.
DNA polymerase ε-dependent modulation of the pausing property of the CMG helicase at the barrier
Kohji Hizume, Shizuko Endo, Sachiko Muramatsu, Takehiko Kobayashi, Hiroyuki Araki
Genes Dev. 2018 Oct 1; 32(19-20): 1315–1320. doi: 10.1101/gad.317073.118
PMCID:
PMC6169835
AbstractArticlePDF–1.3M
11.
Histone H2A‐H2B binding by Pol α in the eukaryotic replisome contributes to the maintenance of repressive chromatin
Cecile Evrin, Joseph D Maman, Aurora Diamante, Luca Pellegrini, Karim Labib
EMBO J. 2018 Oct 1; 37(19): e99021. Published online 2018 Aug 13. doi: 10.15252/embj.201899021
PMCID:
PMC6166128
AbstractArticlePDF–1.5M
12.
A global interaction network maps a wiring diagram of cellular function
Michael Costanzo, Benjamin VanderSluis, Elizabeth N. Koch, Anastasia Baryshnikova, Carles Pons, Guihong Tan, Wen Wang, Matej Usaj, Julia Hanchard, Susan D. Lee, Vicent Pelechano, Erin B. Styles, Maximilian Billmann, Jolanda van Leeuwen, Nydia van Dyk, Zhen-Yuan Lin, Elena Kuzmin, Justin Nelson, Jeff S. Piotrowski, Tharan Srikumar, Sondra Bahr, Yiqun Chen, Raamesh Deshpande, Christoph F. Kurat, Sheena C. Li, Zhijian Li, Mojca Mattiazzi Usaj, Hiroki Okada, Natasha Pascoe, Bryan-Joseph San Luis, Sara Sharifpoor, Emira Shuteriqi, Scott W. Simpkins, Jamie Snider, Harsha Garadi Suresh, Yizhao Tan, Hongwei Zhu, Noel Malod-Dognin, Vuk Janjic, Natasa Przulj, Olga G. Troyanskaya, Igor Stagljar, Tian Xia, Yoshikazu Ohya, Anne-Claude Gingras, Brian Raught, Michael Boutros, Lars M. Steinmetz, Claire L. Moore, Adam P. Rosebrock, Amy A. Caudy, Chad L. Myers, Brenda Andrews, Charles Boone
Science. Author manuscript; available in PMC 2017 Oct 30.
Published in final edited form as: Science. 2016 Sep 23; 353(6306): aaf1420. doi: 10.1126/science.aaf1420
PMCID:
PMC5661885
AbstractArticlePDF–2.6M
13.
Mcm10 promotes rapid isomerization of CMG-DNA for replisome bypass of lagging strand DNA blocks
Lance D Langston, Ryan Mayle, Grant D Schauer, Olga Yurieva, Daniel Zhang, Nina Y Yao, Roxana E Georgescu, Mike E O'Donnell
eLife. 2017; 6: e29118. Published online 2017 Sep 4. doi: 10.7554/eLife.29118
PMCID:
PMC5599239
AbstractArticlePDF–3.8M
14.
An intact Mcm10 coiled-coil interaction surface is important for origin melting, helicase assembly and the recruitment of Pol-α to Mcm2–7
Patricia Perez-Arnaiz, Irina Bruck, Max K. Colbert, Daniel L. Kaplan
Nucleic Acids Res. 2017 Jul 7; 45(12): 7261–7275. Published online 2017 May 16. doi: 10.1093/nar/gkx438
PMCID:
PMC5499591
AbstractArticlePDF–3.7M
15.
CMG–Pol epsilon dynamics suggests a mechanism for the establishment of leading-strand synthesis in the eukaryotic replisome
Jin Chuan Zhou, Agnieszka Janska, Panchali Goswami, Ludovic Renault, Ferdos Abid Ali, Abhay Kotecha, John F. X. Diffley, Alessandro Costa
Proc Natl Acad Sci U S A. 2017 Apr 18; 114(16): 4141–4146. Published online 2017 Apr 3. doi: 10.1073/pnas.1700530114
PMCID:
PMC5402455
AbstractArticlePDF–1.3M
16.
Ufd1-Npl4 Recruit Cdc48 for Disassembly of Ubiquitylated CMG Helicase at the End of Chromosome Replication
Marija Maric, Progya Mukherjee, Michael H. Tatham, Ronald Hay, Karim Labib
Cell Rep. 2017 Mar 28; 18(13): 3033–3042. Published online 2017 Mar 28. doi: 10.1016/j.celrep.2017.03.020
PMCID:
PMC5382235
AbstractArticle
17.
Ctf4 Is a Hub in the Eukaryotic Replisome that Links Multiple CIP-Box Proteins to the CMG Helicase
Fabrizio Villa, Aline C. Simon, Maria Angeles Ortiz Bazan, Mairi L. Kilkenny, David Wirthensohn, Mel Wightman, Dijana Matak-Vinkovíc, Luca Pellegrini, Karim Labib
Mol Cell. 2016 Aug 4; 63(3): 385–396. doi: 10.1016/j.molcel.2016.06.009
PMCID:
PMC4980431
AbstractArticlePDF–4.9M
18.
Ctf4 Links DNA Replication with Sister Chromatid Cohesion Establishment by Recruiting the Chl1 Helicase to the Replisome
Catarina P. Samora, Julie Saksouk, Panchali Goswami, Ben O. Wade, Martin R. Singleton, Paul A. Bates, Armelle Lengronne, Alessandro Costa, Frank Uhlmann
Mol Cell. 2016 Aug 4; 63(3): 371–384. doi: 10.1016/j.molcel.2016.05.036
PMCID:
PMC4980427
AbstractArticle
19.
The Architecture of a Eukaryotic Replisome
Jingchuan Sun, Yi Shi, Roxana E. Georgescu, Zuanning Yuan, Brian T. Chait, Huilin Li, Michael E. O’Donnell
Nat Struct Mol Biol. Author manuscript; available in PMC 2016 Jun 1.
Published in final edited form as: Nat Struct Mol Biol. 2015 Dec; 22(12): 976–982. Published online 2015 Nov 2. doi: 10.1038/nsmb.3113
PMCID:
PMC4849863
AbstractArticlePDF–2.4M
20.
Structure of the eukaryotic replicative CMG helicase and pumpjack motion
Zuanning Yuan, Lin Bai, Jingchuan Sun, Roxana Georgescu, Jun Liu, Michael E. O’Donnell, Huilin Li
Nat Struct Mol Biol. Author manuscript; available in PMC 2016 Aug 8.
Published in final edited form as: Nat Struct Mol Biol. 2016 Mar; 23(3): 217–224. Published online 2016 Feb 8. doi: 10.1038/nsmb.3170
PMCID:
PMC4812828
AbstractArticlePDF–4.2M

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